| 1 | DUOX1, DUOX2, DUOXA1, DUOXA2
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| The Dual Oxidase Duox2 stabilized with DuoxA2 in an enzymatic complex at the surface of the cell produces extracellular H2O2 able to induce DNA damage in an inducible cellular model.
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| Poncelet L, Dumont JE, Miot F, De Deken X.
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| Exp Cell Res 384(1):111620. doi: 10.1016/j.yexcr.2019.111620. Epub 2019 Sep 9.
2019
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| 2 | DUOX1, DUOXA1, HTDI3
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| Identification of Two Missense Mutations in DUOX1 (p.R1307Q) and DUOXA1 (p.R56W) That Can Cause Congenital Hypothyroidism Through Impairing H2O2 Generation.
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| Liu S, Han W, Zang Y, Zang H, Wang F, Jiang P, Wei H, Liu X, Wang Y, Ma X, Ge Y.
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| Front Endocrinol (Lausanne) 10:526. doi: 10.3389/fendo.2019.00526. eCollection 2019. 2019
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| 3 | DUOX1, DUOX2, DUOXA1, DUOXA2
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| Conformation of the N-Terminal Ectodomain Elicits Different Effects on DUOX Function: A Potential Impact on Congenital Hypothyroidism Caused by a H2O2 Production Defect.
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| Louzada RA, Corre R, Ameziane-El-Hassani R, Hecht F, Cazarin J, Buffet C, Carvalho DP, Dupuy C.
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| Thyroid 28(8):1052-1062. doi: 10.1089/thy.2017.0596. Epub 2018 Jul 24.
2018
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| 4 | DUOX1, DUOX2, DUOXA1, DUOXA2, IL13, IL4
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| Thyroid hydrogen peroxide production is enhanced by the Th2 cytokines, IL-4 and IL-13, through increased expression of the dual oxidase 2 and its maturation factor DUOXA2.
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| Raad H, Eskalli Z, Corvilain B, Miot F, De Deken X.
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| Free Radic Biol Med 56:216-25. doi: 10.1016/j.freeradbiomed.2012.09.003. Epub 2012 Sep 23.
2013
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| 5 | DUOX1, DUOX2, DUOXA1
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| Conserved cysteine residues provide a protein-protein interaction surface in dual oxidase (DUOX) proteins.
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| Meitzler JL, Hinde S, Bánfi B, Nauseef WM, Ortiz de Montellano PR.
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| J Biol Chem 288(10):7147-57. doi: 10.1074/jbc.M112.414797. Epub 2013 Jan 28.
2013
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| 6 | DUOX1, DUOX2, DUOXA1, DUOXA2
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| Heterodimerization controls localization of Duox-DuoxA NADPH oxidases in airway cells.
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| Luxen S, Noack D, Frausto M, Davanture S, Torbett BE, Knaus UG.
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| J Cell Sci 122(Pt 8):1238-47. doi: 10.1242/jcs.044123.
2009
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| 7 | DUOX1, DUOX2, DUOXA1, DUOXA2
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| Identification of the maturation factor for dual oxidase. Evolution of an eukaryotic operon equivalent.
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| Grasberger H, Refetoff S.
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| J Biol Chem 281(27):18269-72. Epub 2006 May 1. 2006
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