1 | DROSHA, SUN1
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| The mammalian LINC complex component SUN1 regulates muscle regeneration by modulating drosha activity.
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| Loo TH, Ye X, Chai RJ, Ito M, Bonne G, Ferguson-Smith AC, Stewart CL.
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| Elife 8. pii: e49485. doi: 10.7554/eLife.49485.
2019
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2 | DGCR8, DROSHA
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| DROSHA targets its own transcript to modulate alternative splicing.
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| Lee D, Nam JW, Shin C.
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| RNA NA. 2017 Apr 11. pii: rna.059808.116. doi: 10.1261/rna.059808.116. [Epub ahead of print]
2017
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3 | DGCR8, DICER1, DROSHA
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| Deficiency in DGCR8-dependent canonical microRNAs causes infertility due to multiple abnormalities during uterine development in mice.
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| Kim YS, Kim HR, Kim H, Yang SC, Park M, Yoon JA, Lim HJ, Hong SH, DeMayo FJ, Lydon JP, Choi Y, Lee DR, Song H.
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| Sci Rep 6:20242. doi: 10.1038/srep20242.
2016
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4 | DGCR8, DROSHA
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| Drosha-independent DGCR8/Pasha pathway regulates neuronal morphogenesis.
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| Luhur A, Chawla G, Wu YC, Li J, Sokol NS.
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| Proc Natl Acad Sci U S A 111(4):1421-6. doi: 10.1073/pnas.1318445111. Epub 2014 Jan 13.
2014
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5 | DROSHA, EIF4H
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| Drosha promotes splicing of a pre-microRNA-like alternative exon.
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| Havens MA, Reich AA, Hastings ML.
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| PLoS Genet 10(5):e1004312. doi: 10.1371/journal.pgen.1004312. eCollection 2014 May.
2014
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6 | DROSHA
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| Drosha regulates gene expression independently of RNA cleavage function.
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| Gromak N, Dienstbier M, Macias S, Plass M, Eyras E, Cáceres JF, Proudfoot NJ.
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| Cell Rep 5(6):1499-510. doi: 10.1016/j.celrep.2013.11.032. Epub 2013 Dec 19.
2013
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7 | DROSHA
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| miRNA biogenesis enzyme Drosha is required for vascular smooth muscle cell survival.
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| Fan P, Chen Z, Tian P, Liu W, Jiao Y, Xue Y, Bhattacharya A, Wu J, Lu M, Guo Y, Cui Y, Gu W, Gu W, Yue J.
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| PLoS One 8(4):e60888. doi: 10.1371/journal.pone.0060888. Print 2013.
2013
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8 | DROSHA
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| The microRNA maturation regulator Drosha is an independent predictor of outcome in breast cancer patients.
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| Khoshnaw SM, Rakha EA, Abdel-Fatah T, Nolan CC, Hodi Z, Macmillan RD, Ellis IO, Green AR.
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| Breast Cancer Res Treat 137(1):139-53. doi: 10.1007/s10549-012-2358-0. Epub 2012 Dec 6.
2013
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9 | DGCR8, DROSHA
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| The core microprocessor component DiGeorge syndrome critical region 8 (DGCR8) is a nonspecific RNA-binding protein.
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| Roth BM, Ishimaru D, Hennig M.
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| J Biol Chem 288(37):26785-99. doi: 10.1074/jbc.M112.446880. Epub 2013 Jul 26.
2013
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10 | DROSHA, LIN28A
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| Drosha mediates destabilization of Lin28 mRNA targets.
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| Qiao C, Ma J, Xu J, Xie M, Ma W, Huang Y.
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| Cell Cycle 11(19):3590-8. doi: 10.4161/cc.21871. Epub 2012 Aug 30.
2012
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11 | DROSHA
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| Drosha regulates neurogenesis by controlling neurogenin 2 expression independent of microRNAs.
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| Knuckles P, Vogt MA, Lugert S, Milo M, Chong MM, Hautbergue GM, Wilson SA, Littman DR, Taylor V.
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| Nat Neurosci 15(7):962-9. doi: 10.1038/nn.3139.
2012
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12 | DICER1, DROSHA
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| The RNase III enzyme DROSHA is essential for microRNA production and spermatogenesis.
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| Wu Q, Song R, Ortogero N, Zheng H, Evanoff R, Small CL, Griswold MD, Namekawa SH, Royo H, Turner JM, Yan W.
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| J Biol Chem 287(30):25173-90. doi: 10.1074/jbc.M112.362053. Epub 2012 Jun 4.
2012
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13 | DICER1, DROSHA
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| Inducible deletion of epidermal Dicer and Drosha reveals multiple functions for miRNAs in postnatal skin.
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| Teta M, Choi YS, Okegbe T, Wong G, Tam OH, Chong MM, Seykora JT, Nagy A, Littman DR, Andl T, Millar SE.
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| Development 139(8):1405-16. doi: 10.1242/dev.070920.
2012
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14 | DICER1, DROSHA
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| Site-specific DICER and DROSHA RNA products control the DNA-damage response.
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| Francia S, Michelini F, Saxena A, Tang D, de Hoon M, Anelli V, Mione M, Carninci P, d'Adda di Fagagna F.
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| Nature 488(7410):231-5. doi: 10.1038/nature11179.
2012
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15 | DROSHA
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| Expanding the role of Drosha to the regulation of viral gene expression.
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| Lin YT, Sullivan CS.
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| Proc Natl Acad Sci U S A 108(27):11229-34. doi: 10.1073/pnas.1105799108. Epub 2011 Jun 20.
2011
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16 | DICER1, DROSHA
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| Expression levels of the microRNA processing enzymes Drosha and dicer in epithelial skin cancer.
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| Sand M, Gambichler T, Skrygan M, Sand D, Scola N, Altmeyer P, Bechara FG.
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| Cancer Invest 28(6):649-53. doi: 10.3109/07357901003630918.
2010
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17 | DGCR8, DROSHA
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| Posttranscriptional crossregulation between Drosha and DGCR8.
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| Han J, Pedersen JS, Kwon SC, Belair CD, Kim YK, Yeom KH, Yang WY, Haussler D, Blelloch R, Kim VN.
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| Cell 136(1):75-84. 2009
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18 | DGCR8, DROSHA
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| Genome-wide identification of targets of the drosha-pasha/DGCR8 complex.
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| Kadener S, Rodriguez J, Abruzzi KC, Khodor YL, Sugino K, Marr MT 2nd, Nelson S, Rosbash M.
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| RNA 15(4):537-45. Epub 2009 Feb 17. 2009
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19 | BASP1, BRD9, DROSHA, NDUFS6, NNT, OSMR, PAIP1, PAPD7, RAD1, SDHA, SKP2, TARS
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| Integrative genomics analysis of chromosome 5p gain in cervical cancer reveals target over-expressed genes, including Drosha.
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| Scotto L, Narayan G, Nandula SV, Subramaniyam S, Kaufmann AM, Wright JD, Pothuri B, Mansukhani M, Schneider A, Arias-Pulido H, Murty VV.
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| Mol Cancer 7:58. 2008
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20 | DICER1, DROSHA
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| Evolutionary conservation of a unique amino acid sequence in human DICER protein essential for binding to Argonaute family proteins.
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| Sasaki T, Shimizu N.
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| Gene 396(2):312-20. Epub 2007 Apr 6. 2007
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21 | DICER1, DROSHA
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| Role of Dicer and Drosha for endothelial microRNA expression and angiogenesis.
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| Kuehbacher A, Urbich C, Zeiher AM, Dimmeler S.
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| Circ Res 101(1):59-68. Epub 2007 May 31. 2007
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22 | DGCR8, DICER1, DROSHA
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| MicroRNA biogenesis: isolation and characterization of the microprocessor complex.
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| Gregory RI, Chendrimada TP, Shiekhattar R.
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| Methods Mol Biol 342:33-47. Review. 2006
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23 | DICER1, DROSHA
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| RNASEN regulates cell proliferation and affects survival in esophageal cancer patients.
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| Sugito N, Ishiguro H, Kuwabara Y, Kimura M, Mitsui A, Kurehara H, Ando T, Mori R, Takashima N, Ogawa R, Fujii Y.
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| Clin Cancer Res 12(24):7322-8. Epub 2006 Nov 22. 2006
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24 | DROSHA
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| Efficient processing of primary microRNA hairpins by Drosha requires flanking nonstructured RNA sequences.
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| Zeng Y, Cullen BR.
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| J Biol Chem 280(30):27595-603. Epub 2005 Jun 1. 2005
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25 | DROSHA
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| The nuclear RNase III Drosha initiates microRNA processing.
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| Lee Y, Ahn C, Han J, Choi H, Kim J, Yim J, Lee J, Provost P, Radmark O, Kim S, Kim VN.
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| Nature 425(6956):415-9. 2003
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26 | DROSHA
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| Human RNase III is a 160-kDa protein involved in preribosomal RNA processing.
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| Wu H, Xu H, Miraglia LJ, Crooke ST.
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| J Biol Chem 275(47):36957-65. 2000
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