Citations for
1DROSHA, SUN1
The mammalian LINC complex component SUN1 regulates muscle regeneration by modulating drosha activity.
Loo TH, Ye X, Chai RJ, Ito M, Bonne G, Ferguson-Smith AC, Stewart CL.
Elife 8. pii: e49485. doi: 10.7554/eLife.49485. 2019
2DGCR8, DROSHA
DROSHA targets its own transcript to modulate alternative splicing.
Lee D, Nam JW, Shin C.
RNA NA. 2017 Apr 11. pii: rna.059808.116. doi: 10.1261/rna.059808.116. [Epub ahead of print] 2017
3DGCR8, DICER1, DROSHA
Deficiency in DGCR8-dependent canonical microRNAs causes infertility due to multiple abnormalities during uterine development in mice.
Kim YS, Kim HR, Kim H, Yang SC, Park M, Yoon JA, Lim HJ, Hong SH, DeMayo FJ, Lydon JP, Choi Y, Lee DR, Song H.
Sci Rep 6:20242. doi: 10.1038/srep20242. 2016
4DGCR8, DROSHA
Drosha-independent DGCR8/Pasha pathway regulates neuronal morphogenesis.
Luhur A, Chawla G, Wu YC, Li J, Sokol NS.
Proc Natl Acad Sci U S A 111(4):1421-6. doi: 10.1073/pnas.1318445111. Epub 2014 Jan 13. 2014
5DROSHA, EIF4H
Drosha promotes splicing of a pre-microRNA-like alternative exon.
Havens MA, Reich AA, Hastings ML.
PLoS Genet 10(5):e1004312. doi: 10.1371/journal.pgen.1004312. eCollection 2014 May. 2014
6DROSHA
Drosha regulates gene expression independently of RNA cleavage function.
Gromak N, Dienstbier M, Macias S, Plass M, Eyras E, Cáceres JF, Proudfoot NJ.
Cell Rep 5(6):1499-510. doi: 10.1016/j.celrep.2013.11.032. Epub 2013 Dec 19. 2013
7DROSHA
miRNA biogenesis enzyme Drosha is required for vascular smooth muscle cell survival.
Fan P, Chen Z, Tian P, Liu W, Jiao Y, Xue Y, Bhattacharya A, Wu J, Lu M, Guo Y, Cui Y, Gu W, Gu W, Yue J.
PLoS One 8(4):e60888. doi: 10.1371/journal.pone.0060888. Print 2013. 2013
8DROSHA
The microRNA maturation regulator Drosha is an independent predictor of outcome in breast cancer patients.
Khoshnaw SM, Rakha EA, Abdel-Fatah T, Nolan CC, Hodi Z, Macmillan RD, Ellis IO, Green AR.
Breast Cancer Res Treat 137(1):139-53. doi: 10.1007/s10549-012-2358-0. Epub 2012 Dec 6. 2013
9DGCR8, DROSHA
The core microprocessor component DiGeorge syndrome critical region 8 (DGCR8) is a nonspecific RNA-binding protein.
Roth BM, Ishimaru D, Hennig M.
J Biol Chem 288(37):26785-99. doi: 10.1074/jbc.M112.446880. Epub 2013 Jul 26. 2013
10DROSHA, LIN28A
Drosha mediates destabilization of Lin28 mRNA targets.
Qiao C, Ma J, Xu J, Xie M, Ma W, Huang Y.
Cell Cycle 11(19):3590-8. doi: 10.4161/cc.21871. Epub 2012 Aug 30. 2012
11DROSHA
Drosha regulates neurogenesis by controlling neurogenin 2 expression independent of microRNAs.
Knuckles P, Vogt MA, Lugert S, Milo M, Chong MM, Hautbergue GM, Wilson SA, Littman DR, Taylor V.
Nat Neurosci 15(7):962-9. doi: 10.1038/nn.3139. 2012
12DICER1, DROSHA
The RNase III enzyme DROSHA is essential for microRNA production and spermatogenesis.
Wu Q, Song R, Ortogero N, Zheng H, Evanoff R, Small CL, Griswold MD, Namekawa SH, Royo H, Turner JM, Yan W.
J Biol Chem 287(30):25173-90. doi: 10.1074/jbc.M112.362053. Epub 2012 Jun 4. 2012
13DICER1, DROSHA
Inducible deletion of epidermal Dicer and Drosha reveals multiple functions for miRNAs in postnatal skin.
Teta M, Choi YS, Okegbe T, Wong G, Tam OH, Chong MM, Seykora JT, Nagy A, Littman DR, Andl T, Millar SE.
Development 139(8):1405-16. doi: 10.1242/dev.070920. 2012
14DICER1, DROSHA
Site-specific DICER and DROSHA RNA products control the DNA-damage response.
Francia S, Michelini F, Saxena A, Tang D, de Hoon M, Anelli V, Mione M, Carninci P, d'Adda di Fagagna F.
Nature 488(7410):231-5. doi: 10.1038/nature11179. 2012
15DROSHA
Expanding the role of Drosha to the regulation of viral gene expression.
Lin YT, Sullivan CS.
Proc Natl Acad Sci U S A 108(27):11229-34. doi: 10.1073/pnas.1105799108. Epub 2011 Jun 20. 2011
16DICER1, DROSHA
Expression levels of the microRNA processing enzymes Drosha and dicer in epithelial skin cancer.
Sand M, Gambichler T, Skrygan M, Sand D, Scola N, Altmeyer P, Bechara FG.
Cancer Invest 28(6):649-53. doi: 10.3109/07357901003630918. 2010
17DGCR8, DROSHA
Posttranscriptional crossregulation between Drosha and DGCR8.
Han J, Pedersen JS, Kwon SC, Belair CD, Kim YK, Yeom KH, Yang WY, Haussler D, Blelloch R, Kim VN.
Cell 136(1):75-84. 2009
18DGCR8, DROSHA
Genome-wide identification of targets of the drosha-pasha/DGCR8 complex.
Kadener S, Rodriguez J, Abruzzi KC, Khodor YL, Sugino K, Marr MT 2nd, Nelson S, Rosbash M.
RNA 15(4):537-45. Epub 2009 Feb 17. 2009
19BASP1, BRD9, DROSHA, NDUFS6, NNT, OSMR, PAIP1, PAPD7, RAD1, SDHA, SKP2, TARS
Integrative genomics analysis of chromosome 5p gain in cervical cancer reveals target over-expressed genes, including Drosha.
Scotto L, Narayan G, Nandula SV, Subramaniyam S, Kaufmann AM, Wright JD, Pothuri B, Mansukhani M, Schneider A, Arias-Pulido H, Murty VV.
Mol Cancer 7:58. 2008
20DICER1, DROSHA
Evolutionary conservation of a unique amino acid sequence in human DICER protein essential for binding to Argonaute family proteins.
Sasaki T, Shimizu N.
Gene 396(2):312-20. Epub 2007 Apr 6. 2007
21DICER1, DROSHA
Role of Dicer and Drosha for endothelial microRNA expression and angiogenesis.
Kuehbacher A, Urbich C, Zeiher AM, Dimmeler S.
Circ Res 101(1):59-68. Epub 2007 May 31. 2007
22DGCR8, DICER1, DROSHA
MicroRNA biogenesis: isolation and characterization of the microprocessor complex.
Gregory RI, Chendrimada TP, Shiekhattar R.
Methods Mol Biol 342:33-47. Review. 2006
23DICER1, DROSHA
RNASEN regulates cell proliferation and affects survival in esophageal cancer patients.
Sugito N, Ishiguro H, Kuwabara Y, Kimura M, Mitsui A, Kurehara H, Ando T, Mori R, Takashima N, Ogawa R, Fujii Y.
Clin Cancer Res 12(24):7322-8. Epub 2006 Nov 22. 2006
24DROSHA
Efficient processing of primary microRNA hairpins by Drosha requires flanking nonstructured RNA sequences.
Zeng Y, Cullen BR.
J Biol Chem 280(30):27595-603. Epub 2005 Jun 1. 2005
25DROSHA
The nuclear RNase III Drosha initiates microRNA processing.
Lee Y, Ahn C, Han J, Choi H, Kim J, Yim J, Lee J, Provost P, Radmark O, Kim S, Kim VN.
Nature 425(6956):415-9. 2003
26DROSHA
Human RNase III is a 160-kDa protein involved in preribosomal RNA processing.
Wu H, Xu H, Miraglia LJ, Crooke ST.
J Biol Chem 275(47):36957-65. 2000