Citations for
1ANKK1, DRD2, TTC12
A neurobiological pathway to smoking in adolescence: TTC12-ANKK1-DRD2 variants and reward response.
Macare C, Ducci F, Zhang Y, Ruggeri B, Jia T, Kaakinen M, Kalsi G, Charoen P, Casoni F, Peters J, Bromberg U, Hill M, Buxton J, Blakemore A, Veijola J, Büchel C, Banaschewski T, Bokde ALW, Conrod P, Flor H, Frouin V, Gallinat J, Garavan H, Gowland PA, Heinz A, Ittermann B, Lathrop M, Martinot JL, Paus T, Desrivières S, Munafò M, Järvelin MR, Schumann G; IMAGEN Consortium.
Eur Neuropsychopharmacol 28(10):1103-1114. doi: 10.1016/j.euroneuro.2018.07.101. Epub 2018 Aug 11. 2018
2DRD2, TSPAN7
Functional expression of dopamine D2 receptor is regulated by tetraspanin 7-mediated postendocytic trafficking.
Lee SA, Suh Y, Lee S, Jeong J, Kim SJ, Kim SJ, Park SK.
FASEB J 31(6):2301-2313. doi: 10.1096/fj.201600755RR. Epub 2017 Feb 21. 2017
3DRD1, DRD2
Adolescent Maturation of Dopamine D1 and D2 Receptor Function and Interactions in Rodents.
Dwyer JB, Leslie FM.
PLoS One 11(1):e0146966. doi: 10.1371/journal.pone.0146966. eCollection 2016. 2016
4DRD2
Receptor, Ligand and Transducer Contributions to Dopamine D2 Receptor Functional Selectivity.
Peterson SM, Pack TF, Caron MG.
PLoS One 10(10):e0141637. doi: 10.1371/journal.pone.0141637. eCollection 2015. 2015
5DRD1, DRD2
Differential roles of dopamine D1 and D2 receptor-containing neurons of the nucleus accumbens shell in behavioral sensitization.
Kai N, Nishizawa K, Tsutsui Y, Ueda S, Kobayashi K.
J Neurochem 135(6):1232-41. doi: 10.1111/jnc.13380. Epub 2015 Oct 28. 2015
6DRD2
Distinct regulation of dopamine D2S and D2L autoreceptor signaling by calcium.
Gantz SC, Robinson BG, Buck DC, Bunzow JR, Neve RL, Williams JT, Neve KA.
Elife 4. doi: 10.7554/eLife.09358. 2015
7DRD2
De novo expression of dopamine D2 receptors on microglia after stroke.
Huck JH, Freyer D, Böttcher C, Mladinov M, Muselmann-Genschow C, Thielke M, Gladow N, Bloomquist D, Mergenthaler P, Priller J.
J Cereb Blood Flow Metab 35(11):1804-11. doi: 10.1038/jcbfm.2015.128. Epub 2015 Jun 24. 2015
8DRD2
Elucidation of G-protein and β-arrestin functional selectivity at the dopamine D2 receptor.
Peterson SM, Pack TF, Wilkins AD, Urs NM, Urban DJ, Bass CE, Lichtarge O, Caron MG.
Proc Natl Acad Sci U S A 112(22):7097-102. doi: 10.1073/pnas.1502742112. Epub 2015 May 11. 2015
9DRD2
Evidence for limited D1 and D2 receptor coexpression and colocalization within the dorsal striatum of the neonatal mouse.
Biezonski DK, Trifilieff P, Meszaros J, Javitch JA, Kellendonk C.
J Comp Neurol 523(8):1175-89. doi: 10.1002/cne.23730. Epub 2015 Feb 17. 2015
10DRD2
Dopamine D2 receptors preferentially regulate the development of light responses of the inner retina.
Tian N, Xu HP, Wang P.
Eur J Neurosci 41(1):17-30. doi: 10.1111/ejn.12783. Epub 2014 Nov 13. 2015
11ANKK1, DRD2
Updated findings of the association and functional studies of DRD2/ANKK1 variants with addictions.
Ma Y, Yuan W, Jiang X, Cui WY, Li MD.
Mol Neurobiol 51(1):281-99. doi: 10.1007/s12035-014-8826-2. Epub 2014 Aug 20. 2015
12DRD2, SSTR3
Dopamine 2 and somatostatin 1-5 receptors coexpression in clinically non-functioning pituitary adenomas.
Gabalec F, Drastikova M, Cesak T, Netuka D, Masopust V, Machac J, Marek J, Cap J, Beranek M.
Physiol Res 64(3):369-77. Epub 2014 Dec 22. 2015
13ADBRK1, DRD2, GRK1, NCS1
Neuronal Calcium Sensor-1 Binds the D2 Dopamine Receptor and G-protein-coupled Receptor Kinase 1 (GRK1) Peptides Using Different Modes of Interactions.
Pandalaneni S, Karuppiah V, Saleem M, Haynes LP, Burgoyne RD, Mayans O, Derrick JP, Lian LY.
J Biol Chem 290(30):18744-56. doi: 10.1074/jbc.M114.627059. Epub 2015 May 15. 2015
14DRD2, SESN2
Sestrin2 decreases renal oxidative stress, lowers blood pressure, and mediates dopamine D2 receptor-induced inhibition of reactive oxygen species production.
Yang Y, Cuevas S, Yang S, Villar VA, Escano C, Asico L, Yu P, Jiang X, Weinman EJ, Armando I, Jose PA.
Hypertension 64(4):825-32. doi: 10.1161/HYPERTENSIONAHA.114.03840. Epub 2014 Jul 14. 2014
15DRD2, GNB5, RGS7
G protein beta 5 is targeted to D2-dopamine receptor-containing biochemical compartments and blocks dopamine-dependent receptor internalization.
Octeau JC, Schrader JM, Masuho I, Sharma M, Aiudi C, Chen CK, Kovoor A, Celver J.
PLoS One 9(8):e105791. doi: 10.1371/journal.pone.0105791. eCollection 2014. 2014
16DRD2
Dopamine D2 receptors regulate the anatomical and functional balance of basal ganglia circuitry.
Cazorla M, de Carvalho FD, Chohan MO, Shegda M, Chuhma N, Rayport S, Ahmari SE, Moore H, Kellendonk C.
Neuron 81(1):153-64. doi: 10.1016/j.neuron.2013.10.041. 2014
17CDK5, DRD2
Cdk5 phosphorylates dopamine D2 receptor and attenuates downstream signaling.
Jeong J, Park YU, Kim DK, Lee S, Kwak Y, Lee SA, Lee H, Suh YH, Gho YS, Hwang D, Park SK.
PLoS One 8(12):e84482. doi: 10.1371/journal.pone.0084482. eCollection 2013. 2013
18DRD2
Age-dependent regulation of synaptic connections by dopamine D2 receptors.
Jia JM, Zhao J, Hu Z, Lindberg D, Li Z.
Nat Neurosci 16(11):1627-36. doi: 10.1038/nn.3542. Epub 2013 Oct 13. 2013
19DRD2
Loss of D2 dopamine receptor function modulates cocaine-induced glutamatergic synaptic potentiation in the ventral tegmental area.
Madhavan A, Argilli E, Bonci A, Whistler JL.
J Neurosci 33(30):12329-36. doi: 10.1523/JNEUROSCI.0809-13.2013. 2013
20DRD2
Increasing dopamine D2 receptor expression in the adult nucleus accumbens enhances motivation.
Trifilieff P, Feng B, Urizar E, Winiger V, Ward RD, Taylor KM, Martinez D, Moore H, Balsam PD, Simpson EH, Javitch JA.
Mol Psychiatry 18(9):1025-33. doi: 10.1038/mp.2013.57. Epub 2013 May 28. 2013
21DRD2
Dopamine D2-like receptor signaling suppresses human osteoclastogenesis.
Hanami K, Nakano K, Saito K, Okada Y, Yamaoka K, Kubo S, Kondo M, Tanaka Y.
Bone 56(1):1-8. doi: 10.1016/j.bone.2013.04.019. Epub 2013 Apr 28. 2013
22DRD2
Dopamine facilitates dendritic spine formation by cultured striatal medium spiny neurons through both D1 and D2 dopamine receptors.
Fasano C, Bourque MJ, Lapointe G, Leo D, Thibault D, Haber M, Kortleven C, Desgroseillers L, Murai KK, Trudeau LÉ.
Neuropharmacology 67:432-43. doi: 10.1016/j.neuropharm.2012.11.030. Epub 2012 Dec 8. 2013
23ANKK1, DRD2
Associations of prenatal nicotine exposure and the dopamine related genes ANKK1 and DRD2 to verbal language.
Eicher JD, Powers NR, Cho K, Miller LL, Mueller KL, Ring SM, Tomblin JB, Gruen JR.
PLoS One 8(5):e63762. doi: 10.1371/journal.pone.0063762. Print 2013. 2013
24DRD2, PDE4B, ZNF804A
ZNF804a regulates expression of the schizophrenia-associated genes PRSS16, COMT, PDE4B, and DRD2.
Girgenti MJ, LoTurco JJ, Maher BJ.
PLoS One 7(2):e32404. doi: 10.1371/journal.pone.0032404. Epub 2012 Feb 27. 2012
25DRD2
Altered dendritic distribution of dopamine D2 receptors and reduction in mitochondrial number in parvalbumin-containing interneurons in the medial prefrontal cortex of cannabinoid-1 (CB1) receptor knockout mice.
Fitzgerald ML, Chan J, Mackie K, Lupica CR, Pickel VM.
J Comp Neurol 520(17):4013-31. doi: 10.1002/cne.23141. 2012
26DRD2, TAAR1
Functional interaction between trace amine-associated receptor 1 and dopamine D2 receptor.
Espinoza S, Salahpour A, Masri B, Sotnikova TD, Messa M, Barak LS, Caron MG, Gainetdinov RR.
Mol Pharmacol 80(3):416-25. Epub 2011 Jun 13. 2011
27DRD2, HNRNPM, NOVA1
Regulatory roles of heterogeneous nuclear ribonucleoprotein M and Nova-1 protein in alternative splicing of dopamine D2 receptor pre-mRNA.
Park E, Iaccarino C, Lee J, Kwon I, Baik SM, Kim M, Seong JY, Son GH, Borrelli E, Kim K.
J Biol Chem 286(28):25301-8. doi: 10.1074/jbc.M110.206540. Epub 2011 May 26. 2011
28DRD2
Dopamine D2 receptor gene polymorphisms are associated with suicide attempt in the Japanese population.
Suda A, Kawanishi C, Kishida I, Sato R, Yamada T, Nakagawa M, Hasegawa H, Kato D, Furuno T, Hirayasu Y.
Neuropsychobiology 59(2):130-4. Epub 2009 Apr 22. 2009
29DRD2
C957T polymorphism of the human dopamine D2 receptor gene predicts extrastriatal dopamine receptor availability in vivo.
Hirvonen MM, Lumme V, Hirvonen J, Pesonen U, Någren K, Vahlberg T, Scheinin H, Hietala J.
Prog Neuropsychopharmacol Biol Psychiatry 33(4):630-6. Epub 2009 Mar 11. 2009
30ADRBK1, ADRBK2, DRD2
G protein-coupled receptor kinase-mediated phosphorylation regulates post-endocytic trafficking of the D2 dopamine receptor.
Namkung Y, Dipace C, Javitch JA, Sibley DR.
J Biol Chem 284(22):15038-51. Epub 2009 Mar 30. 2009
31DRD2
Association between dopaminergic genes (SLC6A3 and DRD2) and stuttering among Han Chinese.
Lan J, Song M, Pan C, Zhuang G, Wang Y, Ma W, Chu Q, Lai Q, Xu F, Li Y, Liu L, Wang W.
J Hum Genet 54(8):457-60. Epub 2009 Jul 10.PMID: 19590515 2009
32APOE, COMT, DAO, DRD1, DRD2, DRD4, DTNBP1, GABRB2, GRIN2B, HP, IL1B, MTHFR, PLXNA2, SCZD23, SLC6A4, TP53, TPH1
Systematic meta-analyses and field synopsis of genetic association studies in schizophrenia: the SzGene database.
Allen NC, Bagade S, McQueen MB, Ioannidis JP, Kavvoura FK, Khoury MJ, Tanzi RE, Bertram L.
Nat Genet 40(7):827-34. 2008
33DRD2, S100B
Novel interaction of the dopamine D2 receptor and the Ca2+ binding protein S100B: role in D2 receptor function.
Liu Y, Buck DC, Neve KA.
Mol Pharmacol 74(2):371-8. Epub 2008 Apr 29. 2008
34DRD1, DRD2
D1 and D2 dopamine receptor expression is regulated by direct interaction with the chaperone protein calnexin.
Free RB, Hazelwood LA, Cabrera DM, Spalding HN, Namkung Y, Rankin ML, Sibley DR.
J Biol Chem 282(29):21285-300. Epub 2007 Mar 29. 2007
35DRD2
The Cys allele of the DRD2 Ser311Cys polymorphism has a dominant effect on risk for schizophrenia: evidence from fixed- and random-effects meta-analyses.
Glatt SJ, Jonsson EG.
Am J Med Genet B Neuropsychiatr Genet 141(2):149-54. 2006
36DRD2
Association between the DRD2 A1 allele and opium addiction in the Iranian population.
Shahmoradgoli Najafabadi M, Ohadi M, Joghataie MT, Valaie F, Riazalhosseini Y, Mostafavi H, Mohammadbeigi F, Najmabadi H.
Am J Med Genet B Neuropsychiatr Genet 134(1):39-41. 2005
37COMT, HT2A, DRD2, DRD4, SLC6A3
Genetics and epigenetics in major psychiatric disorders: dilemmas, achievements, applications, and future scope.
Abdolmaleky HM, Thiagalingam S, Wilcox M.
Am J Pharmacogenomics 5(3):149-60. Review. 2005
38ANKK1, DRD2
Identification and characterization of ANKK1: a novel kinase gene closely linked to DRD2 on chromosome band 11q23.1.
Neville MJ, Johnstone EC, Walton RT.
Hum Mutat 23(6):540-5. 2004
39DRD2
Synonymous mutations in the human dopamine receptor D2 (DRD2) affect mRNA stability and synthesis of the receptor
Duan J, Wainwright MS, Comeron JM, Saitou N, Sanders AR, Gelernter J, Gejman PV.
Hum Mol Genet 12(3):205-16. 2003
40CLIC6, DRD2, DRD3, DRD4, MPDZ
CLIC6, a member of the intracellular chloride channel family, interacts with dopamine D(2)-like receptors.
Griffon N, Jeanneteau F, Prieur F, Diaz J, Sokoloff P.
Brain Res Mol Brain Res 117(1):47-57. 2003
41DRD2
Association analysis between two functional dopamine D2 receptor gene polymorphisms and schizophrenia.
Hori H, Ohmori O, Shinkai T, Kojima H, Nakamura J.
Am J Med Genet 105(2):176-8. 2001
42DRD2
Distinct functions of the two isoforms of dopamine D2 receptors.
Usiello A, Baik JH, Rougé-Pont F, Picetti R, Dierich A, LeMeur M, Piazza PV, Borrelli E.
Nature 408(6809):199-203. 2000
43DRD2, MD
Association of a missense change in the D2 dopamine receptor with myoclonus dystonia.
Klein C, et al.
Proc Natl Acad Sci U S A 96(9):5173-6. 1999
44DRD2
DNA methylation at the putative promoter region of the human dopamine D2 receptor gene.
Popendikyte V, et al.
Neuroreport 10(6):1249-55. 1999
45DRD2
Supportive evidence for contribution of the dopamine D2 receptor gene to heritability of stature : linkage and association studies.
Arinami T, Iijima Y, Yamakawa-Kobayashi K, Ishiguro H, Ohtsuki T, Yanagi H, Shimakura Y, Ishikawa H Hamaguchi H.
Ann Hum Genet 63:147-151 1999
46DRD2, DRD3
European multicentre association study of schizophrenia : a study of the DRD2 Ser311cys and DRD3 Ser9Gly polymorphisms.
Spurlock G, Williams J, McGuffin P, Aschauer HN, Lenzinger E, Fuchs K, Sieghart WC, Meszaros K, Fathi N, Laurent C, Mallet J, Macciardi F, Pedrini S, Gill M, Hawi Z, Gibson S, Jazin EE, Yang HT, Adolfsson R, Pato CN, Dourado AM, Owen MJ.
Am J Med Genet 81(1):24-8. 1998
47DRD2
A global survey of haplotype frequencies and linkage disequilibrium at the DRD2 locus.
Kidd KK, et al.
Hum Genet 103 : 211-227. 1998
48DRD2
Dopamine receptors: from structure to function.
Missale C, et al.
Physiol Rev 78(1):189-225. Review. 1998
49DRD2
A functional polymorphism in the promoter region of the dopamine D2 receptor gene is associated with schizophrenia.
Arinami T, et al.
Hum Mol Genet 6 : 577-582. 1997
50DRD2
Further association study on dopamine D2 receptor variant S311C in schizophrenia and affective disorders.
Arinami T, et al.
Am J Med Genet 67 : 133-138. 1996
51DRD2
Lack of association between dopamine D2 receptor gene Cys311 vairant andschizophrenia.
Tanaka T, et al.
Am J Med Genet 67 : 208-211. 1996
52DRD2, DRD3, SLC6A3, TH
Association study of bipolar disorder with candidate genes involved in catecholamine neurotransmission : DRD2,DRD3,DAT1, and TH genes.
Souery D, et al.
Am J Med Genet 67 : 551-555. 1996
53NCAM1, DRD2
New localization of NCAM, proximal to DRD2 at chromosome 11q23.
Telatar M, et al.
Mamm Genome 6 : 59-60. 1995
54DRD2
A new polymorphism in the gene for the dopamine D2 receptor.
Poduslo SE, et al.
Hum Genet 95 : 603-604. 1995
55DRD2
PCR detection of the TaqA RFLP at the DRD2 locus.
Grandy DK, et al.
Hum Mol Genet 2 : 2197. 1993
56DRD2
Linkage map of eight human chromosome 11q markers, including DRD2, spanning 60cM.
Gelernter J, et al.
Cytogenet Cell Genet 60 : 26-28. 1992
57DRD2
A rare FokI RFLP in the human dopamine D2 receptor gene (DRD2).
Lu CY, et al.
Hum Genet 89 : 360. 1992
58DRD2
Structure and linkage of the D2 dopamine receptor and neural cell adhesion molecule genes on human chromosome 11q23.
Eubanks JH, et al.
Genomics 14 : 1010-1018. 1992
59DRD2
Use of polymerase chain reaction nad denaturing gradient gel electrophoresis to identify polymorphisms in three exons of dopamine D2 receptor gene in schizophrenic and delusional patients.
Catalano M, et al.
Neuropsychobiology 26 : 1-3. 1992
60DRD2
Detection and characterization of additional DNA polymorphisms in the dopamine D2 receptor gene.
Hauge XY, et al.
Genomics 10 : 527-530. 1991
61GABRB1, FCGR3B, CD247, DRD2, CD4, IGF1R
Genetic mapping of six human genes.
Dean M, et al.
(HGM11) Cytogenet Cell Genet 58 : 1853. 1991
62D11S144, D11S351, D11S385, MMP3, NCAM1, DRD2
Improved maximum separation of 3 pairs of markers on chromosome 11q22-23.
Formstone CJ, et al.
(HGM11) Cytogenet Cell Genet 58 : 1959. 1991
63DRD2
A new TaqI RFLP within intron 2 of human dopamine D2 receptor gene (DRD2).
Parsian A, et al.
Nucleic Acids Res 19 : 6977. 1991
64MMP3, NCAM1, DRD2, D11S35, D11S385, D11S144, D11S351
Fine mapping of the chromosome 11q22-23 region using PFGE, linkage and haplotype analysis; localization of the gene for ataxia telangiectasia to a 5cM region flanked by NCAM/DRD2 and STMY/CJ52.75, phi 2.22.
McConville CM, et al.
Nucleic Acids Res 18 : 4335-4343. 1990
65DRD2
D2 dopamine receptor locus (probe hD2G1) maps close to D11S29 (probe L7) and is also linked to PBGD (probe PBGD0.0) and D11S84 (probe p-2-7-ID6) on 11q.
Gelernter J, et al.
(HGM10) Cytogenet Cell Genet 51 : 1002. 1989
66DRD2
Dopamine D2 receptor gene maps to human chromosome 11q22-q23 and identifies a TaqI RFLP.
Grandy DK, et al.
(HGM10) Cytogenet Cell Genet 51 : 1007. 1989
67DRD2
The human dopamine D2 receptor gene is located on chromosome 11 at q22-q23 and identifies a TaqI RFLP.
Grandy DK, et al.
Am J Hum Genet 45 : 778-785. 1989
68DRD2
The dopamine D2 receptor : two molecular forms generated by alternative splicing.
Toso RD, et al.
EMBO J 8 : 4025-4034. 1989