Citations for
1DPP8, DPP8, NLRP1
DPP8/9 inhibitors are universal activators of functional NLRP1 alleles.
Gai K, Okondo MC, Rao SD, Chui AJ, Ball DP, Johnson DC, Bachovchin DA.
Cell Death Dis 10(8):587. doi: 10.1038/s41419-019-1817-5. 2019
2CARD8, DPP8, DPP9, NLRP1
DPP8/DPP9 inhibition elicits canonical Nlrp1b inflammasome hallmarks in murine macrophages.
de Vasconcelos NM, Vliegen G, Gonçalves A, De Hert E, Martín-Pérez R, Van Opdenbosch N, Jallapally A, Geiss-Friedlander R, Lambeir AM, Augustyns K, Van Der Veken P, De Meester I, Lamkanfi M.
Life Sci Alliance 2(1). pii: e201900313. doi: 10.26508/lsa.201900313. Print 2019 Feb. 2019
3DPP4, DPP8, DPP9
Structures and mechanism of dipeptidyl peptidases 8 and 9, important players in cellular homeostasis and cancer.
Ross B, Krapp S, Augustin M, Kierfersauer R, Arciniega M, Geiss-Friedlander R, Huber R.
Proc Natl Acad Sci U S A 115(7):E1437-E1445. doi: 10.1073/pnas.1717565115. Epub 2018 Jan 30. 2018
4DPP8
Targeting dipeptidyl peptidase 8 genes inhibits proliferation, migration and invasion by inhibition of cyclin D1 and MMP2MMP9 signal pathway in cervical cancer.
Chen Y, Liu F, Wu K, Wu W, Wu H, Zhang W.
J Gene Med 20(12):e3056. doi: 10.1002/jgm.3056. Epub 2018 Nov 8. 2018
5DPP8, DPP9
Inhibition of dipeptidyl peptidase 8/9 impairs preadipocyte differentiation.
Han R, Wang X, Bachovchin W, Zukowska Z, Osborn JW.
Sci Rep 5:12348. doi: 10.1038/srep12348. 2015
6DPP8, DPP9
Regulation of dipeptidyl peptidase 8 and 9 expression in activated lymphocytes and injured liver.
Chowdhury S, Chen Y, Yao TW, Ajami K, Wang XM, Popov Y, Schuppan D, Bertolino P, McCaughan GW, Yu DM, Gorrell MD.
World J Gastroenterol 19(19):2883-93. doi: 10.3748/wjg.v19.i19.2883. 2013
7DPP8, DPP9
The SUMO1-E67 interacting loop peptide is an allosteric inhibitor of the dipeptidyl peptidases 8 and 9.
Pilla E, Kilisch M, Lenz C, Urlaub H, Geiss-Friedlander R.
J Biol Chem 288(45):32787-96. doi: 10.1074/jbc.M113.489179. Epub 2013 Sep 26. 2013
8DPP8, DPP9, SUMO1, SUMO2, UBA2
A novel SUMO1-specific interacting motif in dipeptidyl peptidase 9 (DPP9) that is important for enzymatic regulation.
Pilla E, Möller U, Sauer G, Mattiroli F, Melchior F, Geiss-Friedlander R.
J Biol Chem 287(53):44320-9. doi: 10.1074/jbc.M112.397224. Epub 2012 Nov 14. 2012
9DPP8, DPP9
Role of a propeller loop in the quaternary structure and enzymatic activity of prolyl dipeptidases DPP-IV and DPP9.
Tang HK, Chen KC, Liou GG, Cheng SC, Chien CH, Tang HY, Huang LH, Chang HP, Chou CY, Chen X.
FEBS Lett 585(21):3409-14. doi: 10.1016/j.febslet.2011.10.009. Epub 2011 Oct 10. 2011
10DPP8, DPP9, HRAS
A novel role of dipeptidyl peptidase 9 in epidermal growth factor signaling.
Yao TW, Kim WS, Yu DM, Sharbeen G, McCaughan GW, Choi KY, Xia P, Gorrell MD.
Mol Cancer Res 9(7):948-59. doi: 10.1158/1541-7786.MCR-10-0272. Epub 2011 May 26. 2011
11DPP8, DPP9
Enzyme activity and immunohistochemical localization of dipeptidyl peptidase 8 and 9 in male reproductive tissues.
Dubois V, Van Ginneken C, De Cock H, Lambeir AM, Van der Veken P, Augustyns K, Chen X, Scharpé S, De Meester I.
J Histochem Cytochem 57(6):531-41. doi: 10.1369/jhc.2009.952739. Epub 2009 Feb 2. 2009
12CXCL10, CXCL11, CXCL12, DPP8
Stromal cell-derived factors 1alpha and 1beta, inflammatory protein-10 and interferon-inducible T cell chemo-attractant are novel substrates of dipeptidyl peptidase 8.
Ajami K, Pitman MR, Wilson CH, Park J, Menz RI, Starr AE, Cox JH, Abbott CA, Overall CM, Gorrell MD.
FEBS Lett 582(5):819-25. Epub 2008 Feb 12. Erratum in: FEBS Lett. 2008 Apr 2;582(7):1168. 2008
13DPP8
Investigation of the dimer interface and substrate specificity of prolyl dipeptidase DPP8.
Lee HJ, Chen YS, Chou CY, Chien CH, Lin CH, Chang GG, Chen X.
J Biol Chem 281(50):38653-62. Epub 2006 Oct 13. 2006
14DPP8, DPP9
Extraenzymatic functions of the dipeptidyl peptidase IV-related proteins DP8 and DP9 in cell adhesion, migration and apoptosis.
Yu DM, Wang XM, McCaughan GW, Gorrell MD.
FEBS J 273(11):2447-60. 2006
15DPP8, DPP9
Dipeptidyl peptidases 8 and 9: specificity and molecular characterization compared with dipeptidyl peptidase IV.
Bjelke JR, Christensen J, Nielsen PF, Branner S, Kanstrup AB, Wagtmann N, Rasmussen HB.
Biochem J 396(2):391-9. 2006
16DPP10, DPP9, DPP8, DPP6
Cloning and characterization of dipeptidyl peptidase 10, a new member of an emerging subgroup of serine proteases.
Qi SY, Riviere PJ, Trojnar J, Junien JL, Akinsanya KO.
Biochem J 373(Pt 1):179-89. 2003
17DPP8, DPP9
Cloning, expression and chromosomal localization of a novel human dipeptidyl peptidase (DPP) IV homolog, DPP8.
Abbott CA, Yu DM, Woollatt E, Sutherland GR, McCaughan GW, Gorrell MD.
Eur J Biochem 267(20):6140-50. 2000