1 | ACE2, AGTR2, CLEC4G, DPP4, KREMEN1, LDLRAD3, NPR1, SLC4A1, TMEM30A
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| SARS-CoV-2 cell entry beyond the ACE2 receptor.
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| Alipoor SD, Mirsaeidi M.
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| Mol Biol Rep. Nov;49(11):10715-10727. doi: 10.1007/s11033-022-07700-x. Epub 2022 Jun 26 2022
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2 | ACE2, DPP4, EMILIN1, EMILIN2
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| Expression profiles of the SARS-CoV-2 host invasion genes in nasopharyngeal and oropharyngeal swabs of COVID-19 patients
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| Amati F, Vancheri C, Latini A, Colona VL, Grelli S, D'Apice MR, Balestrieri E, Passarelli C, Minutolo A, Loddo S, Di Lorenzo A, Rogliani P, Andreoni M, Novelli G.
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| Heliyon. Oct;6(10):e05143. doi: 10.1016/j.heliyon.2020.e05143. Epub 2020 Oct 1. 2020
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3 | DPP4, DPP8, DPP9
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| Structures and mechanism of dipeptidyl peptidases 8 and 9, important players in cellular homeostasis and cancer.
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| Ross B, Krapp S, Augustin M, Kierfersauer R, Arciniega M, Geiss-Friedlander R, Huber R.
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| Proc Natl Acad Sci U S A 115(7):E1437-E1445. doi: 10.1073/pnas.1717565115. Epub 2018 Jan 30.
2018
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4 | DPP4, TP53
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| The Tumor Suppressor p53 Limits Ferroptosis by Blocking DPP4 Activity.
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| Xie Y, Zhu S, Song X, Sun X, Fan Y, Liu J, Zhong M, Yuan H, Zhang L, Billiar TR, Lotze MT, Zeh HJ 3rd, Kang R, Kroemer G, Tang D.
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| Cell Rep 20(7):1692-1704. doi: 10.1016/j.celrep.2017.07.055.
2017
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5 | CSF2, DPP4
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| DPP4 truncated GM-CSF and IL-3 manifest distinct receptor-binding and regulatory functions compared with their full-length forms.
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| O'Leary HA, Capitano M, Cooper S, Mantel C, Boswell HS, Kapur R, Ramdas B, Chan R, Deng L, Qu CK, Broxmeyer HE.
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| Leukemia 31(11):2468-2478. doi: 10.1038/leu.2017.98. Epub 2017 Mar 27.
2017
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6 | DPP4, PLG
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| Plasminogen deficiency is associated with improved glucose tolerance, and lower DPP-4 activity.
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| Kanno Y, Sakai A, Miyashita M, Tsuchida K, Matsuo O.
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| Diabetes Res Clin Pract 120:190-3. doi: 10.1016/j.diabres.2016.08.007.
2016
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7 | DPP4, POL2RA
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| Nuclear localization of CD26 induced by a humanized monoclonal antibody inhibits tumor cell growth by modulating of POLR2A transcription.
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| Yamada K, Hayashi M, Madokoro H, Nishida H, Du W, Ohnuma K, Sakamoto M, Morimoto C, Yamada T.
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| PLoS One 8(4):e62304. doi: 10.1371/journal.pone.0062304. Print 2013.
2013
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8 | DPP4, ANPEP
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| Inhibitors of dipeptidyl peptidase IV and aminopeptidase N target major pathogenetic steps in acne initiation.
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| Thielitz A, Reinhold D, Vetter R, Bank U, Helmuth M, Hartig R, Wrenger S, Wiswedel I, Lendeckel U, Kahne T, Neubert K, Faust J, Zouboulis CC, Ansorge S, Gollnick H.
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| J Invest Dermatol 127(5):1042-51. Epub 2006 Jun 15. 2007
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9 | DPP4, GPC3, SGBS
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| The Simpson-Golabi-Behmel syndrome causative glypican-3, binds to and inhibits the dipeptidyl peptidase activity of CD26.
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| Davoodi J, Kelly J, Gendron NH, MacKenzie AE.
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| Proteomics 7(13):2300-10.
2007
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10 | HNF1A, HNF1B, DPP4
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| Mutant HNF-1alpha and mutant HNF-1beta identified in MODY3 and MODY5 downregulate DPP-IV gene expression in Caco-2 cells.
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| Gu N, Adachi T, Matsunaga T, Takeda J, Tsujimoto G, Ishihara A, Yasuda K, Tsuda K.
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| Biochem Biophys Res Commun 346(3):1016-23. Epub 2006 Jun 9. 2006
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11 | ADA, DPP4
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| CD26, adenosine deaminase, and adenosine receptors mediate costimulatory signals in the immunological synapse.
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| Pacheco R, Martinez-Navio JM, Lejeune M, Climent N, Oliva H, Gatell JM, Gallart T, Mallol J, Lluis C, Franco R.
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| Proc Natl Acad Sci U S A 102(27):9583-8. Epub 2005 Jun 27. 2005
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12 | HNF1A, HNF1B, DPP4, ACE2, SPP1
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| Identification of target genes of the transcription factor HNF1beta and HNF1alpha in a human embryonic kidney cell line.
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| Senkel S, Lucas B, Klein-Hitpass L, Ryffel GU.
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| Biochim Biophys Acta 1731(3):179-90. Epub 2005 Nov 2. 2005
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13 | DPP4, HNF1A
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| Regulation of the gene for human dipeptidyl peptidase IV by hepatocyte nuclear factor 1 alpha.
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| Erickson RH, et al.
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| Biochem J 338 ( Pt 1):91-7. 1999
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14 | APC, BRCA1, DPP4, MLH1, MSH2, MSH6, NF1, PMS2, RB1, TP53, VHL, WT1, FAP
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| Tumour suppressor gene mutations in humans and mice : parallels and contrasts.
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| Hooper ML.
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| EMBO J 17(23):6783-9. 1998
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15 | DPP4
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| Assignment of the DPP4 gene encoding adenosine deaminase binding protein (CD26/dipeptidylpeptidase IV) to 2q23.
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| Mathew S, et al.
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| Genomics 22 : 211-212. 1994
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16 | DPP4
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| Genomic organization, exact localization, and tissue expression of the human CD26 (dipeptidyl peptidase IV) gene.
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| Abbott CA, et al.
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| Immunogenetics 40 : 331-338. 1994
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17 | DPP4
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| Regional localization of DPP4 (alias CD26 and ADCP2) to chromosome 2q24.
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| Darmoul D, et al.
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| Somat Cell Mol Genet 20 : 345-351. 1994
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18 | DPP4
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| An EcoRI polymorphism within the dipeptidyl peptidase IV (DPPIV) gene.
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| Abbott CA, et al.
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| Hum Mol Genet 2 : 1507. 1993
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19 | DPP4
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| Isolation of a cDNA probe for the human intestinal dipeptidylpeptidase IV and assignment of the gene locus DPP4 to chromosome 2.
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| Darmoul D, et al.
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| Ann Hum Genet 54 : 191-197. 1990
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20 | MDH1, DPP4
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| Assignment of a structural gene for adenosine deaminase complexing protein (ADCP) to human chromosome 2 in interspecific somatic cell hybrids.
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| Herbschleb-Voogt E, et al.
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| Cytogenet Cell Genet 25 : 163-164. 1979
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21 | DPP4
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| Genes on human chromosomes 2 and 6 are required for expression of the adenosine deaminase complexing protein (ADCP) in humanXmouse somatic cell hybrids.
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| Koch GA, et al.
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| Cytogenet Cell Genet 25 : 174. 1979
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