| 1 | CALCRL, DOCK1, FCHO2, LRCH4, PLA2G4A
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| Identifying a novel 5-gene signature predicting clinical outcomes in acute myeloid leukemia. 2021 PMID:
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| Sha K, Lu Y, Zhang P, Pei R, Shi X, Fan Z, Chen L.
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| Clin Transl Oncol. Mar;23(3):648-656. doi: 10.1007/s12094-020-02460-1. Epub 2020 Aug 10. 2021
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| 2 | DOCK1, ELMO1, ELMO2, ELMO3, MACF1
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| ELMO recruits actin cross-linking family 7 (ACF7) at the cell membrane for microtubule capture and stabilization of cellular protrusions.
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| Margaron Y, Fradet N, Côté JF.
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| J Biol Chem 288(2):1184-99. doi: 10.1074/jbc.M112.431825. Epub 2012 Nov 26. 2013
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| 3 | CYTH2, DOCK1, GRASP
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| The scaffolding protein GRASP/Tamalin directly binds to Dock180 as well as to cytohesins facilitating GTPase crosstalk in epithelial cell migration.
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| Attar MA, Santy LC.
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| BMC Cell Biol 14:9. doi: 10.1186/1471-2121-14-9.
2013
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| 4 | DOCK1, DOCK5
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| The Rac-specific exchange factors Dock1 and Dock5 are dispensable for the establishment of the glomerular filtration barrier in vivo.
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| Laurin M, Dumouchel A, Fukui Y, Côté JF.
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| Small GTPases 4(4):221-30. doi: 10.4161/sgtp.27430.
2013
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| 5 | DOCK1, DOCK5
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| Phosphatidic acid-dependent recruitment and function of the Rac activator DOCK1 during dorsal ruffle formation.
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| Sanematsu F, Nishikimi A, Watanabe M, Hongu T, Tanaka Y, Kanaho Y, Côté JF, Fukui Y.
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| J Biol Chem 288(12):8092-100. doi: 10.1074/jbc.M112.410423.
2013
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| 6 | DOCK1
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| Rac-specific guanine nucleotide exchange factor DOCK1 is a critical regulator of HER2-mediated breast cancer metastasis.
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| Laurin M, Huber J, Pelletier A, Houalla T, Park M, Fukui Y, Haibe-Kains B, Muller WJ, Côté JF.
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| Proc Natl Acad Sci U S A 110(18):7434-9. doi: 10.1073/pnas.1213050110.
2013
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| 7 | CYTH2, DOCK1, GRASP
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| PDZ-scaffold protein, Tamalin promotes dendritic outgrowth and arborization in rat hippocampal neuron.
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| Mo J, Choi S, Ahn PG, Sun W, Lee HW, Kim H.
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| Biochem Biophys Res Commun 422(2):250-5. doi: 10.1016/j.bbrc.2012.04.136. Epub 2012 Apr 30.
2012
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| 8 | DOCK1, ELMO1, RHOG
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| The RhoG/ELMO1/Dock180 signaling module is required for spine morphogenesis in hippocampal neurons.
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| Kim JY, Oh MH, Bernard LP, Macara IG, Zhang H.
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| J Biol Chem 286(43):37615-24. doi: 10.1074/jbc.M111.268029. Epub 2011 Sep 7.
2011
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| 9 | DOCK1, DOCK2, DOCK3, DOCK4, WASF1
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| Dock3 induces axonal outgrowth by stimulating membrane recruitment of the WAVE complex.
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| Namekata K, Harada C, Taya C, Guo X, Kimura H, Parada LF, Harada T.
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| Proc Natl Acad Sci U S A 107(16):7586-91. Epub 2010 Apr 5.
2010
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| 10 | ADGRB1, DOCK1, ELMO1
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| Unexpected requirement for ELMO1 in clearance of apoptotic germ cells in vivo.
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| Elliott MR, Zheng S, Park D, Woodson RI, Reardon MA, Juncadella IJ, Kinchen JM, Zhang J, Lysiak JJ, Ravichandran KS.
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| Nature 467(7313):333-7.PMID: 20844538 2010
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| 11 | CYTH2, DOCK1, GRASP, IPCEF1
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| GRASP and IPCEF promote ARF-to-Rac signaling and cell migration by coordinating the association of ARNO/cytohesin 2 with Dock180.
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| White DT, McShea KM, Attar MA, Santy LC.
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| Mol Biol Cell 21(4):562-71. doi: 10.1091/mbc.E09-03-0217. Epub 2009 Dec 16. 2010
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| 12 | DEL10QD, DOCK1
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| Identification of critical regions for clinical features of distal 10q deletion syndrome.
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| Yatsenko SA, Kruer MC, Bader PI, Corzo D, Schuette J, Keegan CE, Nowakowska B, Peacock S, Cai WW, Peiffer DA, Gunderson KL, Ou Z, Chinault AC, Cheung SW.
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| Clin Genet 76(1):54-62. Epub 2009 Jun 22. 2009
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| 13 | DOCK1, DOCK2
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| Role of DOCK2 and DOCK180 in fetal thymus colonization.
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| Lei Y, Liu C, Saito F, Fukui Y, Takahama Y.
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| Eur J Immunol 39(10):2695-702. doi: 10.1002/eji.200939630.
2009
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| 14 | DOCK1, DOCK5
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| DOCK5 and DOCK1 regulate Caco-2 intestinal epithelial cell spreading and migration on collagen IV.
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| Sanders MA, Ampasala D, Basson MD.
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| J Biol Chem 284(1):27-35. doi: 10.1074/jbc.M808010200.
2009
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| 15 | DOCK1, NTN1
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| Netrin signal transduction and the guanine nucleotide exchange factor DOCK180 in attractive signaling.
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| Li X, Gao X, Liu G, Xiong W, Wu J, Rao Y.
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| Nat Neurosci 11(1):28-35. Epub 2007 Dec 9. 2008
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| 16 | DOCK1, ELMO1
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| An alpha-helical extension of the ELMO1 pleckstrin homology domain mediates direct interaction to DOCK180 and is critical in Rac signaling.
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| Komander D, Patel M, Laurin M, Fradet N, Pelletier A, Barford D, Côté JF.
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| Mol Biol Cell 19(11):4837-51. Epub 2008 Sep 3.
2008
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| 17 | DOCK1, SNX5
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| The DHR1 domain of DOCK180 binds to SNX5 and regulates cation-independent mannose 6-phosphate receptor transport.
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| Hara S, Kiyokawa E, Iemura S, Natsume T, Wassmer T, Cullen PJ, Hiai H, Matsuda M.
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| Mol Biol Cell 19(9):3823-35. Epub 2008 Jul 2.
2008
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| 18 | DOCK1, DOCK5
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| The atypical Rac activator Dock180 (Dock1) regulates myoblast fusion in vivo.
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| Laurin M, Fradet N, Blangy A, Hall A, Vuori K, Côté JF.
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| Proc Natl Acad Sci U S A 105(40):15446-51. doi: 10.1073/pnas.0805546105.
2008
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| 19 | ADGRB1, DOCK1, ELMO1
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| BAI1 is an engulfment receptor for apoptotic cells upstream of the ELMO/Dock180/Rac module.
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| Park D, Tosello-Trampont AC, Elliott MR, Lu M, Haney LB, Ma Z, Klibanov AL, Mandell JW, Ravichandran KS.
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| Nature 450(7168):430-4. 2007
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| 20 | DOCK1, DOCK10, DOCK11, DOCK9
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| CZH proteins: a new family of Rho-GEFs.
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| Meller N, Merlot S, Guda C.
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| J Cell Sci 118(Pt 21):4937-46. Review. 2005
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| 21 | DOCK1,ELMO1,ELMO2,RHOG
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| RhoG activates Rac1 by direct interaction with the Dock180-binding protein Elmo.
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| Katoh H, Negishi M.
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| Nature 424(6947):461-4. 2003
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| 22 | CRK, DOCK1, ELMO1, ELMO2, ELMO3, RAC1
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| CED-12/ELMO, a novel member of the CrkII/Dock180/Rac pathway, is required for phagocytosis and cell migration.
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| Gumienny TL, Brugnera E, Tosello-Trampont AC, Kinchen JM, Haney LB, Nishiwaki K, Walk SF, Nemergut ME, Macara IG, Francis R, Schedl T, Qin Y, Van Aelst L, Hengartner MO, Ravichandran KS.
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| Cell 107(1):27-41. 2001
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| 23 | DOCK1, RAPGEF1
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| Chromosomal mapping of the gene encoding DOCK180, a major Crk-binding protein, to 10q26.13-q26.3 by fluorescence in situ hybridization.
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| Takai S, et al.
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| Genomics 35 : 403-404. 1996
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