| 1 | DNMT3A, METTL4
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| Dissecting the role of RNA modification regulatory proteins in melanoma.
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| Malvi P, Wang B, Shah S, Gupta R.
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| Oncotarget 10(38):3745-3759. eCollection 2019 Jun 4.
2019
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| 2 | DNMT1, DNMT3A, MBD4
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| Epigenetic regulation of regulatory T cells in patients with abdominal aortic aneurysm.
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| Xia Q, Zhang J, Han Y, Zhang X, Jiang H, Lun Y, Wu X, Gang Q, Liu Z, Böckler D, Duan Z, Xin S.
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| FEBS Open Bio. Jun;9(6):1137-1143. doi: 10.1002/2211-5463.12643. Epub 2019 May 14. 2019
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| 3 | AKT3, BRWD3, CLOVES, DNMT3A, DNMT3OGS, EZH2, GPC3, HIST1H1E, MCAUTS, MPPH2, MRD35, MRX93, MSMR, MSMS, MTOR, NFIX, NSD1, OGID1, PIK3CA, PPP2R5D, PTEN, SGBS, STOL1, WVSS1, WVSS2
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| Mutations in Epigenetic Regulation Genes Are a Major Cause of Overgrowth with Intellectual Disability.
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| Tatton-Brown K, Loveday C, Yost S, Clarke M, Ramsay E, Zachariou A, Elliott A, Wylie H, Ardissone A, Rittinger O, Stewart F, Temple IK, Cole T; Childhood Overgrowth Collaboration, Mahamdallie S, Seal S, Ruark E, Rahman N.
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| Am J Hum Genet 100(5):725-736. doi: 10.1016/j.ajhg.2017.03.010. 2017
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| 4 | DNMT3A, EID3
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| EID3 directly associates with DNMT3A during transdifferentiation of human umbilical cord mesenchymal stem cells to NPC-like cells.
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| Luo L, Chen WJ, Yin JQ, Xu RX.
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| Sci Rep 7:40463. doi: 10.1038/srep40463.
2017
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| 5 | DNMT3A, GBX2
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| The epigenetic modifier DNMT3A is necessary for proper otic placode formation.
|
| Roellig D, Bronner ME.
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| Dev Biol 411(2):294-300. doi: 10.1016/j.ydbio.2016.01.034.
2016
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| 6 | DNMT3A
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| Dnmt3a in the Medial Prefrontal Cortex Regulates Anxiety-Like Behavior in Adult Mice.
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| Elliott E, Manashirov S, Zwang R, Gil S, Tsoory M, Shemesh Y, Chen A.
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| J Neurosci 36(3):730-40. doi: 10.1523/JNEUROSCI.0971-15.2016.
2016
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| 7 | DNMT3A
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| Clinicopathologic Effect of DNMT3A Mutation in Adult T-Cell Acute Lymphoblastic Leukemia.
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| Aref S, El Menshawy N, El-Ghonemy MS, Zeid TA, El-Baiomy MA.
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| Clin Lymphoma Myeloma Leuk 16(1):43-8. doi: 10.1016/j.clml.2015.11.003.
2016
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| 8 | DNMT3A
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| PML-RARA requires DNA methyltransferase 3A to initiate acute promyelocytic leukemia.
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| Cole CB, Verdoni AM, Ketkar S, Leight ER, Russler-Germain DA, Lamprecht TL, Demeter RT, Magrini V, Ley TJ.
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| J Clin Invest 126(1):85-98. doi: 10.1172/JCI82897.
2016
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| 9 | DNMT3A, TET2
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| DNMT3A and TET2 compete and cooperate to repress lineage-specific transcription factors in hematopoietic stem cells.
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| Zhang X, Su J, Jeong M, Ko M, Huang Y, Park HJ, Guzman A, Lei Y, Huang YH, Rao A, Li W, Goodell MA.
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| Nat Genet 48(9):1014-23. doi: 10.1038/ng.3610. Epub 2016 Jul 18.
2016
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| 10 | DNMT3A
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| High frequency of additional gene mutations in acute myeloid leukemia with MLL partial tandem duplication: DNMT3A mutation is associated with poor prognosis.
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| Kao HW, Liang DC, Kuo MC, Wu JH, Dunn P, Wang PN, Lin TL, Shih YS, Liang ST, Lin TH, Lai CY, Lin CH, Shih LY.
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| Oncotarget 6(32):33217-25. doi: 10.18632/oncotarget.5202.
2015
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| 11 | DNMT3A
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| DNMT3A intragenic hypomethylation is associated with adverse prognosis in acute myeloid leukemia.
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| Zhang YY, Yao DM, Zhu XW, Zhou JD, Ma JC, Yang J, Wen XM, Guo H, Lin J, Qian J.
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| Leuk Res 39(10):1041-7. doi: 10.1016/j.leukres.2015.06.015.
2015
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| 12 | DNMT3A
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| DNMT3A moderates cognitive decline in subjects with mild cognitive impairment: replicated evidence from two mild cognitive impairment cohorts.
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| Chouliaras L, Kenis G, Visser PJ, Scheltens P, Tsolaki M, Jones RW, Kehoe PG, Graff C, Girtler NG, Wallin ÅK, Rikkert MO, Spiru L, Elias-Sonnenschein LS, Ramakers IH, Pishva E, van Os J, Steinbusch HW, Verhey FR, van den Hove DL, Rutten BP.
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| Epigenomics 7(4):533-7. doi: 10.2217/epi.15.22.
2015
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| 13 | DNMT3A, DNMT3B
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| De novo DNA Methyltransferases Dnmt3a and Dnmt3b regulate the onset of Igκ light chain rearrangement during early B-cell development.
|
| Manoharan A, Du Roure C, Rolink AG, Matthias P.
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| Eur J Immunol 45(8):2343-55. doi: 10.1002/eji.201445035.
2015
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| 14 | DNMT3A, DNMT3B
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| Targeted disruption of DNMT1, DNMT3A and DNMT3B in human embryonic stem cells.
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| Liao J, Karnik R, Gu H, Ziller MJ, Clement K, Tsankov AM, Akopian V, Gifford CA, Donaghey J, Galonska C, Pop R, Reyon D, Tsai SQ, Mallard W, Joung JK, Rinn JL, Gnirke A, Meissner A.
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| Nat Genet 47(5):469-78. doi: 10.1038/ng.3258.
2015
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| 15 | DNMT3A
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| DNA methyltransferase 3a regulates osteoclast differentiation by coupling to an S-adenosylmethionine-producing metabolic pathway.
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| Nishikawa K, Iwamoto Y, Kobayashi Y, Katsuoka F, Kawaguchi S, Tsujita T, Nakamura T, Kato S, Yamamoto M, Takayanagi H, Ishii M.
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| Nat Med 21(3):281-7. doi: 10.1038/nm.3774.
2015
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| 16 | DNMT3A, TBRS
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| Mutations in the DNA methyltransferase gene DNMT3A cause an overgrowth syndrome with intellectual disability.
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| Tatton-Brown K, Seal S, Ruark E, Harmer J, Ramsay E, Del Vecchio Duarte S, Zachariou A, Hanks S, O'Brien E, Aksglaede L, Baralle D, Dabir T, Gener B, Goudie D, Homfray T, Kumar A, Pilz DT, Selicorni A, Temple IK, Van Maldergem L, Yachelevich N; Childhood Overgrowth Consortium, van Montfort R, Rahman N.
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| Nat Genet 46(4):385-8. doi: 10.1038/ng.2917. Epub 2014 Mar 9. Erratum in: Nat Genet. 2014 Jun;46(6):657.
2014
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| 17 | DNMT3A, DNMT3B
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| Ontogeny of CpG island methylation and specificity of DNMT3 methyltransferases during embryonic development in the mouse.
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| Auclair G, Guibert S, Bender A, Weber M.
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| Genome Biol 15(12):545.
2014
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| 18 | DNMT3A
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| Dnmt3a in Sim1 neurons is necessary for normal energy homeostasis.
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| Kohno D, Lee S, Harper MJ, Kim KW, Sone H, Sasaki T, Kitamura T, Fan G, Elmquist JK.
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| J Neurosci 34(46):15288-96. doi: 10.1523/JNEUROSCI.1316-14.2014.
2014
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| 19 | DNMT3A, DNMT3B
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| Dnmt3a and Dnmt3b have overlapping and distinct functions in hematopoietic stem cells.
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| Challen GA, Sun D, Mayle A, Jeong M, Luo M, Rodriguez B, Mallaney C, Celik H, Yang L, Xia Z, Cullen S, Berg J, Zheng Y, Darlington GJ, Li W, Goodell MA.
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| Cell Stem Cell 15(3):350-64. doi: 10.1016/j.stem.2014.06.018.
2014
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| 20 | DNMT1, DNMT3A
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| Selective role for DNMT3a in learning and memory.
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| Morris MJ, Adachi M, Na ES, Monteggia LM.
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| Neurobiol Learn Mem 115:30-7. doi: 10.1016/j.nlm.2014.06.005.
2014
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| 21 | DNMT3A, DNMT3OGS
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| Mutations in the DNA methyltransferase gene DNMT3A cause an overgrowth syndrome with intellectual disability.
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| Tatton-Brown K, Seal S, Ruark E, Harmer J, Ramsay E, Del Vecchio Duarte S, Zachariou A, Hanks S, O'Brien E, Aksglaede L, Baralle D, Dabir T, Gener B, Goudie D, Homfray T, Kumar A, Pilz DT, Selicorni A, Temple IK, Van Maldergem L, Yachelevich N; Childhood Overgrowth Consortium.
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| Nat Genet 46(4):385-8. doi: 10.1038/ng.2917. Erratum in: Nat Genet. 2014 Jun;46(6):657.
2014
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| 22 | DNMT3A, DNMT3L
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| Forced expression of DNA methyltransferases during oocyte growth accelerates the establishment of methylation imprints but not functional genomic imprinting.
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| Hara S, Takano T, Fujikawa T, Yamada M, Wakai T, Kono T, Obata Y.
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| Hum Mol Genet 23(14):3853-64. doi: 10.1093/hmg/ddu100.
2014
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| 23 | DNMT3A, PADI4
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| Citrullination of DNMT3A by PADI4 regulates its stability and controls DNA methylation
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| Deplus R, Denis H, Putmans P, Calonne E, Fourrez M, Yamamoto K, Suzuki A, Fuks F.
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| Nucleic Acids Res. Jul;42(13):8285-96. doi: 10.1093/nar/gku522. Epub 2014 Jun 23. 2014
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| 24 | DNMT3A, STAT4
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| Opposing roles of STAT4 and Dnmt3a in Th1 gene regulation.
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| Pham D, Yu Q, Walline CC, Muthukrishnan R, Blum JS, Kaplan MH.
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| J Immunol 191(2):902-11. doi: 10.4049/jimmunol.1203229.
2013
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| 25 | DNMT1, DNMT3A, DNMT3B
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| DNA 5-methylcytosine demethylation activities of the mammalian DNA methyltransferases.
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| Chen CC, Wang KY, Shen CK.
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| J Biol Chem 288(13):9084-91. doi: 10.1074/jbc.M112.445585.
2013
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| 26 | DNMT3A, DNMT3B, TCL1A
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| Tcl1 protein functions as an inhibitor of de novo DNA methylation in B-cell chronic lymphocytic leukemia (CLL).
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| Palamarchuk A, Yan PS, Zanesi N, Wang L, Rodrigues B, Murphy M, Balatti V, Bottoni A, Nazaryan N, Alder H, Rassenti L, Kipps TJ, Freitas M, Croce CM, Pekarsky Y.
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| Proc Natl Acad Sci U S A 109(7):2555-60. doi: 10.1073/pnas.1200003109. Epub 2012 Jan 30.
2012
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| 27 | DNMT3A, DNMT3B
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| The mammalian de novo DNA methyltransferases DNMT3A and DNMT3B are also DNA 5-hydroxymethylcytosine dehydroxymethylases.
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| Chen CC, Wang KY, Shen CK.
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| J Biol Chem 287(40):33116-21.
2012
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| 28 | DNMT3A
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| Dnmt3a protects active chromosome domains against cancer-associated hypomethylation.
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| Raddatz G, Gao Q, Bender S, Jaenisch R, Lyko F.
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| PLoS Genet 8(12):e1003146. doi: 10.1371/journal.pgen.1003146. Epub 2012 Dec 20.
2012
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| 29 | DNMT3A, DNMT3B
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| Nucleosomes containing methylated DNA stabilize DNA methyltransferases 3A/3B and ensure faithful epigenetic inheritance.
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| Sharma S, De Carvalho DD, Jeong S, Jones PA, Liang G.
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| PLoS Genet 7(2):e1001286.
2011
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| 30 | DNMT3A
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| DNMT3A mutations in acute myeloid leukemia.
|
| Shah MY, Licht JD.
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| Nat Genet 43(4):289-90.
2011
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| 31 | DNMT3A
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| Exome sequencing identifies somatic mutations of DNA methyltransferase gene DNMT3A in acute monocytic leukemia.
|
| Yan XJ, Xu J, Gu ZH, Pan CM, Lu G, Shen Y, Shi JY, Zhu YM, Tang L, Zhang XW, Liang WX, Mi JQ, Song HD, Li KQ, Chen Z, Chen SJ.
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| Nat Genet 43(4):309-15.
2011
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| 32 | DNMT3A
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| Characterization of DNA-binding activity in the N-terminal domain of the DNA methyltransferase Dnmt3a.
|
| Suetake I, Mishima Y, Kimura H, Lee YH, Goto Y, Takeshima H, Ikegami T, Tajima S.
|
| Biochem J 437(1):141-8.
2011
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| 33 | DNMT3A, DNMT3B
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| Deletion of the de novo DNA methyltransferase Dnmt3a promotes lung tumor progression.
|
| Gao Q, Steine EJ, Barrasa MI, Hockemeyer D, Pawlak M, Fu D, Reddy S, Bell GW, Jaenisch R.
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| Proc Natl Acad Sci U S A 108(44):18061-6. doi: 10.1073/pnas.1114946108. Epub 2011 Oct 19.
2011
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| 34 | DNMT3A
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| Dnmt3a is essential for hematopoietic stem cell differentiation.
|
| Challen GA, Sun D, Jeong M, Luo M, Jelinek J, Berg JS, Bock C, Vasanthakumar A, Gu H, Xi Y, Liang S, Lu Y, Darlington GJ, Meissner A, Issa JP, Godley LA, Li W, Goodell MA.
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| Nat Genet 44(1):23-31. doi: 10.1038/ng.1009.
2011
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| 35 | DNMT3A, EZH2, KDM6A
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| Mutational spectrum analysis of chronic myelomonocytic leukemia includes genes associated with epigenetic regulation: UTX, EZH2, and DNMT3A.
|
| Jankowska AM, Makishima H, Tiu RV, Szpurka H, Huang Y, Traina F, Visconte V, Sugimoto Y, Prince C, O'Keefe C, Hsi ED, List A, Sekeres MA, Rao A, McDevitt MA, Maciejewski JP.
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| Blood 118(14):3932-41. doi: 10.1182/blood-2010-10-311019. Epub 2011 Aug 9.
2011
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| 36 | DNMT1, DNMT3A
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| Dnmt1 and Dnmt3a maintain DNA methylation and regulate synaptic function in adult forebrain neurons.
|
| Feng J, Zhou Y, Campbell SL, Le T, Li E, Sweatt JD, Silva AJ, Fan G.
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| Nat Neurosci. 13(4):423-30. 2010
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| 37 | DNMT3A
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| Chromatin methylation activity of Dnmt3a and Dnmt3a/3L is guided by interaction of the ADD domain with the histone H3 tail.
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| Zhang Y, Jurkowska R, Soeroes S, Rajavelu A, Dhayalan A, Bock I, Rathert P, Brandt O, Reinhardt R, Fischle W, Jeltsch A.
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| Nucleic Acids Res. 38(13):4246-53. 2010
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| 38 | DNMT3A
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| Dnmt3a-dependent nonpromoter DNA methylation facilitates transcription of neurogenic genes.
|
| Wu H, Coskun V, Tao J, Xie W, Ge W, Yoshikawa K, Li E, Zhang Y, Sun YE.
|
| Science. 329(5990):444-8. 2010
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| 39 | DNMT3A
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| Dnmt3a regulates emotional behavior and spine plasticity in the nucleus accumbens.
|
| LaPlant Q, Vialou V, Covington HE 3rd, Dumitriu D, Feng J, Warren BL, Maze I, Dietz DM, Watts EL, Iñiguez SD, Koo JW, Mouzon E, Renthal W, Hollis F, Wang H, Noonan MA, Ren Y, Eisch AJ, Bolaños CA, Kabbaj M, Xiao G, Neve RL, Hurd YL, Oosting RS, Fan G, Morrison JH, Nestler EJ.
|
| Nat Neurosci. 13(9):1137-43. 2010
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| 40 | CDH1, DNMT3A, EHMT1, MPHOSPH8, SETDB2
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| Methyl-H3K9-binding protein MPP8 mediates E-cadherin gene silencing and promotes tumour cell motility and invasion.
|
| Kokura K, Sun L, Bedford MT, Fang J.
|
| EMBO J 29(21):3673-87. Epub 2010 Sep 24.PMID: 20871592 2010
|
| 41 | CARD9, DNMT3A, ERAP2, FUT2, PTGER4, TNFSF11
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| Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.
|
| Franke A, McGovern DP, Barrett JC, Wang K, Radford-Smith GL, Ahmad T, Lees CW, Balschun T, Lee J, Roberts R, Anderson CA, Bis JC, Bumpstead S, Ellinghaus D, Festen EM, Georges M, Green T, Haritunians T, Jostins L, Latiano A, Mathew CG, Montgomery GW, Prescott NJ, Raychaudhuri S, Rotter JI, Schumm P, Sharma Y, Simms LA, Taylor KD, Whiteman D, Wijmenga C, Baldassano RN, Barclay M, Bayless TM, Brand S, Büning C, Cohen A, Colombel JF, Cottone M, Stronati L, Denson T, De Vos M, D'Inca R, Dubinsky M, Edwards C, Florin T, Franchimont D, Gearry R, Glas J, Van Gossum A, Guthery SL, Halfvarson J, Verspaget HW, Hugot JP, Karban A, Laukens D, Lawrance I, Lemann M, Levine A, Libioulle C, Louis E, Mowat C, Newman W, Panés J, Phillips A, Proctor DD, Regueiro M, Russell R, Rutgeerts P, Sanderson J, Sans M, Seibold F, Steinhart AH, Stokkers PC, Torkvist L, Kullak-Ublick G, Wilson D, Walters T, Targan SR, Brant SR, Rioux JD, D'Amato M, Weersma RK, Kugathasan S, Griffiths AM, Mansfield JC, Vermeire S, Duerr RH, Silverberg MS, Satsangi J, Schreiber S, Cho JH, Annese V, Hakonarson H, Daly MJ, Parkes M.
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| Nat Genet 42(12):1118-25.
2010
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| 42 | DNMT3A, DNMT3B
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| DNA methyltransferase DNMT3b protein overexpression as a prognostic factor in patients with diffuse large B-cell lymphomas.
|
| Amara K, Ziadi S, Hachana M, Soltani N, Korbi S, Trimeche M.
|
| Cancer Sci 101(7):1722-30. Epub 2010 Mar 19.
2010
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| 43 | DNMT3A
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| SALL3 interacts with DNMT3A and shows the ability to inhibit CpG island methylation in hepatocellular carcinoma
|
| Shikauchi Y, Saiura A, Kubo T, Niwa Y, Yamamoto J, Murase Y, Yoshikawa H.
|
| Mol Cell Biol. 29(7):1944-58 2009
|
| 44 | DNMT3A, PRMT5
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| PRMT5-mediated methylation of histone H4R3 recruits DNMT3A, coupling histone and DNA methylation in gene silencing.
|
| Zhao Q, Rank G, Tan YT, Li H, Moritz RL, Simpson RJ, Cerruti L, Curtis DJ, Patel DJ, Allis CD, Cunningham JM, Jane SM.
|
| Nat Struct Mol Biol 16(3):304-11. Epub 2009 Feb 22.
2009
|
| 45 | DNMT3A, DNMT3B
|
| Selective anchoring of DNA methyltransferases 3A and 3B to nucleosomes containing methylated DNA.
|
| Jeong S, Liang G, Sharma S, Lin JC, Choi SH, Han H, Yoo CB, Egger G, Yang AS, Jones PA.
|
| Mol Cell Biol 29(19):5366-76. Epub 2009 Jul 20.
2009
|
| 46 | DNMT3A, TSIX, XIST
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| Enhanced reprogramming of Xist by induced upregulation of Tsix and Dnmt3a.
|
| Do JT, Han DW, Gentile L, Sobek-Klocke I, Stehling M, Schöler HR.
|
| Stem Cells 26(11):2821-31. Epub 2008 Aug 28.
2008
|
| 47 | DNMT3A
|
| MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B
|
| Fabbri, M.; Garzon, R.; Cimmino, A.; Liu, Z.; Zanesi, N.; Callegari, E.; Liu, S.; Alder, H.; Costinean, S.; Fernandez-Cymering, C.; Volinia, S.; Guler, G.; Morrison, C. D.; Chan, K. K.; Marcucci, G.; Calin, G. A.; Huebner, K.; Croce, C. M.
|
| Proc. Nat. Acad. Sci 104: 15805-15810 2007
|
| 48 | DNMT3A
|
| Structure of Dnmt3a bound to Dnmt3L suggests a model for de novo DNA methylation
|
| Jia, D.; Jurkowska, R. Z.; Zhang, X.; Jeltsch, A.; Cheng, X.
|
| Nature 449: 248-251 2007
|
| 49 | CBX4, DNMT3A
|
| Polycomb protein Cbx4 promotes SUMO modification of de novo DNA methyltransferase Dnmt3a.
|
| Li B, Zhou J, Liu P, Hu J, Jin H, Shimono Y, Takahashi M, Xu G.
|
| Biochem J 405(2):369-78.
2007
|
| 50 | DNMT3A
|
| The histone methyltransferase SETDB1 and the DNA methyltransferase DNMT3A interact directly and localize to promoters silenced in cancer cells.
|
| Li H, Rauch T, Chen ZX, Szabó PE, Riggs AD, Pfeifer GP.
|
| J Biol Chem. 281(28):19489-500. 2006
|
| 51 | DNMT3A
|
| Myc represses transcription through recruitment of DNA methyltransferase corepressor.
|
| Brenner C, Deplus R, Didelot C, Loriot A, Viré E, De Smet C, Gutierrez A, Danovi D, Bernard D, Boon T, Pelicci PG, Amati B, Kouzarides T, de Launoit Y, Di Croce L, Fuks F.
|
| EMBO J. 24(2):336-46. 2005
|
| 52 | DNMT3L, DNMT3A
|
| Essential role for de novo DNA methyltransferase Dnmt3a in paternal and maternal imprinting.
|
| Kaneda M, Okano M, Hata K, Sado T, Tsujimoto N, Li E, Sasaki H.
|
| Nature 429(6994):900-3. 2004
|
| 53 | DNMT3A, DNMT3B
|
| Chromatin targeting of de novo DNA methyltransferases by the PWWP domain.
|
| Ge YZ, Pu MT, Gowher H, Wu HP, Ding JP, Jeltsch A, Xu GL.
|
| J Biol Chem 279(24):25447-54. Epub 2004 Mar 3. 2004
|
| 54 | DNMT1, DNMT3B, DNMT3A
|
| Effects of chromatin structure on the enzymatic and DNA binding functions of DNA methyltransferases DNMT1 and Dnmt3a in vitro.
|
| Robertson AK, Geiman TM, Sankpal UT, Hager GL, Robertson KD.
|
| Biochem Biophys Res Commun 322(1):110-8. 2004
|
| 55 | DNMT3A
|
| DNMT3L stimulates the DNA methylation activity of Dnmt3a and Dnmt3b through a direct interaction.
|
| Suetake I, Shinozaki F, Miyagawa J, Takeshima H, Tajima S.
|
| J Biol Chem. 279(26):27816-23. 2004
|
| 56 | DNMT3A
|
| Modification of de novo DNA methyltransferase 3a (Dnmt3a) by SUMO-1 modulates its interaction with histone deacetylases (HDACs) and its capacity to repress transcription.
|
| Ling Y, Sankpal UT, Robertson AK, McNally JG, Karpova T, Robertson KD.
|
| Nucleic Acids Res. 32(2):598-610. 2004
|
| 57 | DNMT3A
|
| Over-expression of DNA methyltransferases and CDKN2A gene methylation status in squamous cell carcinoma of the oral cavity.
|
| Yakushiji T, Uzawa K, Shibahara T, Noma H, Tanzawa H.
|
| Int J Oncol 22(6):1201-7. 2003
|
| 58 | DNMT3A
|
| Interactions within the mammalian DNA methyltransferase family.
|
| Margot JB, Ehrenhofer-Murray AE, Leonhardt H.
|
| BMC Mol Biol. 30;4:7. 2003
|
| 59 | DNMT1, DNMT3A
|
| Dnmt3a and Dnmt1 functionally cooperate during de novo methylation of DNA.
|
| Fatemi M, Hermann A, Gowher H, Jeltsch A.
|
| Eur J Biochem 269(20):4981-4. 2002
|
| 60 | DNMT3A ,DNMT3B
|
| The human DNA methyltransferases DNMT3A and DNMT3B have two types of promoters with different CpG contents.
|
| Yanagisawa Y, Ito E, Yuasa Y, Maruyama K.
|
| Biochim Biophys Acta 1577(3):457-65. 2002
|
| 61 | DNMT3A
|
| A novel Dnmt3a isoform produced from an alternative promoter localizes to euchromatin and its expression correlates with active de novo methylation.
|
| Chen T, Ueda Y, Xie S, Li E.
|
| J Biol Chem 277(41):38746-54. Epub 2002 Jul 22. 2002
|
| 62 | DNMT3A
|
| Identification and characterization of alternatively spliced variants of DNA methyltransferase 3a in mammalian cells.
|
| Weisenberger DJ, Velicescu M, Preciado-Lopez MA, Gonzales FA, Tsai YC, Liang G, Jones PA.
|
| Gene 298(1):91-9. 2002
|
| 63 | DNMT3A
|
| Co-operation and communication between the human maintenance and de novo DNA (cytosine-5) methyltransferases
|
| Kim, G.-D.; Ni, J.; Kelesoglu, N.; Roberts, R. J.; Pradhan, S.
|
| EMBO J. 21: 4183-4195 2002
|
| 64 | DNMT3A
|
| Dnmt3L cooperates with the Dnmt3 family of de novo DNA methyltransferases to establish maternal imprints in mice.
|
| Hata K, Okano M, Lei H, Li E.
|
| Development. 129(8):1983-93. 2002
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| 65 | DNMT3A, HDAC1, ZBTB18
|
| Dnmt3a binds deacetylases and is recruited by a sequence-specific repressor to silence transcription.
|
| Fuks F, Burgers WA, Godin N, Kasai M, Kouzarides T.
|
| EMBO J 20(10):2536-2544. 2001
|
| 66 | DNMT3A, DNMT3B
|
| Cloning, expression and chromosome locations of the human DNMT3 gene family.
|
| Xie S, et al.
|
| Gene 236(1):87-95 1999
|
| 67 | DNMT1, DNMT3A, DNMT3B
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