| 1 | ASH2L, DNMT1, MT1A, UHRF1, YWHAE, ZNF479
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| ZNF479 downregulates metallothionein-1 expression by regulating ASH2L and DNMT1 in hepatocellular carcinoma
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| Wu YJ, Ko BS, Liang SM, Lu YJ, Jan YJ, Jiang SS, Shyue SK, Chen L, Liou JY.
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| Cell Death Dis. May 28;10(6):408. doi: 10.1038/s41419-019-1651-9. 2019
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| 2 | DNMT1, DNMT3A, MBD4
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| Epigenetic regulation of regulatory T cells in patients with abdominal aortic aneurysm.
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| Xia Q, Zhang J, Han Y, Zhang X, Jiang H, Lun Y, Wu X, Gang Q, Liu Z, Böckler D, Duan Z, Xin S.
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| FEBS Open Bio. Jun;9(6):1137-1143. doi: 10.1002/2211-5463.12643. Epub 2019 May 14. 2019
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| 3 | DNMT1, MBD4, TNFRSF18
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| DNMT1 cooperates with MBD4 to inhibit the expression of Glucocorticoid-induced TNFR-related protein in human T cells
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| Wang S, Li Y, Zhu F, Lin F, Luo X, Zhao B, Zhang P, Li D, Gao Y, Liang R, Liu L, Tsun A, Yuan X, Wu K, Li B.
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| FEBS Lett. Jul;591(13):1929-1939. doi: 10.1002/1873-3468.12690. Epub 2017 Jun 10. 2017
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| 4 | DNMT1
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| Crystal Structure of Human DNA Methyltransferase 1.
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| Zhang ZM, Liu S, Lin K, Luo Y, Perry JJ, Wang Y, Song J.
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| J Mol Biol 427(15):2520-31. doi: 10.1016/j.jmb.2015.06.001. Epub 2015 Jun 10.
2015
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| 5 | DNMT1
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| Dnmt1 is essential to maintain progenitors in the perinatal intestinal epithelium.
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| Elliott EN, Sheaffer KL, Schug J, Stappenbeck TS, Kaestner KH.
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| Development 142(12):2163-72. doi: 10.1242/dev.117341. Epub 2015 May 28.
2015
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| 6 | ADCADN, DNMT1, HSANDHL
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| Defects of mutant DNMT1 are linked to a spectrum of neurological disorders.
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| Baets J, Duan X, Wu Y, Smith G, Seeley WW, Mademan I, McGrath NM, Beadell NC, Khoury J, Botuyan MV, Mer G, Worrell GA, Hojo K, DeLeon J, Laura M, Liu YT, Senderek J, Weis J, Van den Bergh P, Merrill SL, Reilly MM, Houlden H, Grossman M, Scherer SS, De Jonghe P, Dyck PJ, Klein CJ.
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| Brain 138(Pt 4):845-61. doi: 10.1093/brain/awv010. Epub 2015 Feb 11.
2015
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| 7 | DNMT1, UHRF1
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| The UHRF1 protein stimulates the activity and specificity of the maintenance DNA methyltransferase DNMT1 by an allosteric mechanism.
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| Bashtrykov P, Jankevicius G, Jurkowska RZ, Ragozin S, Jeltsch A.
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| J Biol Chem 289(7):4106-15. doi: 10.1074/jbc.M113.528893. Epub 2013 Dec 24.
2014
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| 8 | DNMT1, RB1
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| RB maintains quiescence and prevents premature senescence through upregulation of DNMT1 in mesenchymal stromal cells.
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| Lin SP, Chiu FY, Wang Y, Yen ML, Kao SY, Hung SC.
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| Stem Cell Reports 3(6):975-86. doi: 10.1016/j.stemcr.2014.10.002. Epub 2014 Nov 6.
2014
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| 9 | DNMT1
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| A nucleolin-DNMT1 regulatory axis in acute myeloid leukemogenesis.
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| Shen N, Yan F, Pang J, Wu LC, Al-Kali A, Litzow MR, Liu S.
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| Oncotarget 5(14):5494-509.
2014
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| 10 | DNMT1
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| Efficient translation of Dnmt1 requires cytoplasmic polyadenylation and Musashi binding elements.
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| Rutledge CE, Lau HT, Mangan H, Hardy LL, Sunnotel O, Guo F, MacNicol AM, Walsh CP, Lees-Murdock DJ.
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| PLoS One 9(2):e88385. doi: 10.1371/journal.pone.0088385. eCollection 2014.
2014
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| 11 | DNMT1, MBD4
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| MBD4 cooperates with DNMT1 to mediate methyl-DNA repression and protects mammalian cells from oxidative stress.
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| Laget S, Miotto B, Chin HG, Estève PO, Roberts RJ, Pradhan S, Defossez PA.
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| Epigenetics 9(4):546-56. doi: 10.4161/epi.27695. Epub 2014 Jan 16.
2014
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| 12 | DNMT1
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| Regulation of protein stability of DNA methyltransferase 1 by post-translational modifications.
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| Scott A, Song J, Ewing R, Wang Z.
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| Acta Biochim Biophys Sin (Shanghai) 46(3):199-203. doi: 10.1093/abbs/gmt146. Epub 2014 Jan 3. Review.
2014
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| 13 | DNMT1, UHRF1
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| The DNA methyltransferase Dnmt1 directly interacts with the SET and RING finger-associated (SRA) domain of the multifunctional protein Uhrf1 to facilitate accession of the catalytic center to hemi-methylated DNA.
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| Berkyurek AC, Suetake I, Arita K, Takeshita K, Nakagawa A, Shirakawa M, Tajima S.
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| J Biol Chem 289(1):379-86. doi: 10.1074/jbc.M113.523209. Epub 2013 Nov 19.
2014
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| 14 | BCL11A, DNMT1, MYB
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| Transcriptional regulators Myb and BCL11A interplay with DNA methyltransferase 1 in developmental silencing of embryonic and fetal β-like globin genes.
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| Roosjen M, McColl B, Kao B, Gearing LJ, Blewitt ME, Vadolas J.
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| FASEB J 28(4):1610-20. doi: 10.1096/fj.13-242669.
2014
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| 15 | DNMT1, DNMT3A
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| Selective role for DNMT3a in learning and memory.
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| Morris MJ, Adachi M, Na ES, Monteggia LM.
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| Neurobiol Learn Mem 115:30-7. doi: 10.1016/j.nlm.2014.06.005.
2014
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| 16 | BCL11A, DNMT1, KDM1A, RCOR1
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| Corepressor-dependent silencing of fetal hemoglobin expression by BCL11A.
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| Xu J, Bauer DE, Kerenyi MA, Vo TD, Hou S, Hsu YJ, Yao H, Trowbridge JJ, Mandel G, Orkin SH.
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| Proc Natl Acad Sci U S A 110(16):6518-23. doi: 10.1073/pnas.1303976110. Epub 2013 Apr 1.
2013
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| 17 | DNMT1, UHRF1
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| UHRF1 targets DNMT1 for DNA methylation through cooperative binding of hemi-methylated DNA and methylated H3K9.
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| Liu X, Gao Q, Li P, Zhao Q, Zhang J, Li J, Koseki H, Wong J.
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| Nat Commun 4:1563. doi: 10.1038/ncomms2562.
2013
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| 18 | DNMT1
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| DNMT1 is regulated by ATP-citrate lyase and maintains methylation patterns during adipocyte differentiation.
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| Londoño Gentile T, Lu C, Lodato PM, Tse S, Olejniczak SH, Witze ES, Thompson CB, Wellen KE.
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| Mol Cell Biol 33(19):3864-78. doi: 10.1128/MCB.01495-12. Epub 2013 Jul 29.
2013
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| 19 | DNMT1, NBN
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| Regulatory interaction between NBS1 and DNMT1 responding to DNA damage.
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| Hayashi N, Kobayashi M, Shamma A, Morimura Y, Takahashi C, Yamamoto K.
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| J Biochem 154(5):429-35. doi: 10.1093/jb/mvt071. Epub 2013 Aug 5.
2013
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| 20 | AIM1, DNMT1
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| DNMT1 and AIM1 Imprinting in human placenta revealed through a genome-wide screen for allele-specific DNA methylation.
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| Das R, Lee YK, Strogantsev R, Jin S, Lim YC, Ng PY, Lin XM, Chng K, Yeo GSh, Ferguson-Smith AC, Ding C.
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| BMC Genomics 14:685. doi: 10.1186/1471-2164-14-685.
2013
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| 21 | DNMT1
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| Essential role for Dnmt1 in the prevention and maintenance of MYC-induced T-cell lymphomas.
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| Peters SL, Hlady RA, Opavska J, Klinkebiel D, Novakova S, Smith LM, Lewis RE, Karpf AR, Simpson MA, Wu L, Opavsky R.
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| Mol Cell Biol 33(21):4321-33. doi: 10.1128/MCB.00776-13. Epub 2013 Sep 3.
2013
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| 22 | DNMT1, DNMT3A, DNMT3B
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| DNA 5-methylcytosine demethylation activities of the mammalian DNA methyltransferases.
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| Chen CC, Wang KY, Shen CK.
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| J Biol Chem 288(13):9084-91. doi: 10.1074/jbc.M112.445585.
2013
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| 23 | DNMT1, DUP19P
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| 19p13.2 microduplication causes a Sotos syndrome-like phenotype and alters gene expression.
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| Lehman A, du Souich C, Chai D, Eydoux P, Huang J, Fok A, Avila L, Swingland J, Delaney A, McGillivray B, Goldowitz D, Argiropoulos B, Kobor M, Boerkoel C.
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| Clin Genet 81(1):56-63. doi: 10.1111/j.1399-0004.2010.01615.x. Epub 2011 Jan 19.
2012
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| 24 | DNMT1, DNMT3, POLR3A
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| Regulation of human RNA polymerase III transcription by DNMT1 and DNMT3a DNA methyltransferases.
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| Selvakumar T, Gjidoda A, Hovde SL, Henry RW.
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| J Biol Chem. 287(10):7039-50. 2012
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| 25 | DNMT1
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| Structure-based mechanistic insights into DNMT1-mediated maintenance DNA methylation.
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| Song J, Teplova M, Ishibe-Murakami S, Patel DJ.
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| Science 335(6069):709-12. doi: 10.1126/science.1214453.
2012
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| 26 | ADCADN, DNMT1
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| Mutations in DNMT1 cause autosomal dominant cerebellar ataxia, deafness and narcolepsy.
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| Winkelmann J, Lin L, Schormair B, Kornum BR, Faraco J, Plazzi G, Melberg A, Cornelio F, Urban AE, Pizza F, Poli F, Grubert F, Wieland T, Graf E, Hallmayer J, Strom TM, Mignot E.
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| Hum Mol Genet 21(10):2205-10. doi: 10.1093/hmg/dds035. Epub 2012 Feb 9.
2012
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| 27 | DNMT1, HSANDHL
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| Mutations in DNMT1 cause hereditary sensory neuropathy with dementia and hearing loss.
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| Klein CJ, Botuyan MV, Wu Y, Ward CJ, Nicholson GA, Hammans S, Hojo K, Yamanishi H, Karpf AR, Wallace DC, Simon M, Lander C, Boardman LA, Cunningham JM, Smith GE, Litchy WJ, Boes B, Atkinson EJ, Middha S, B Dyck PJ, Parisi JE, Mer G, Smith DI, Dyck PJ.
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| Nat Genet 43(6):595-600. Epub 2011 May 1. 2011
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| 28 | DNMT1, SETD7
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| A methylation and phosphorylation switch between an adjacent lysine and serine determines human DNMT1 stability.
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| Estève PO, Chang Y, Samaranayake M, Upadhyay AK, Horton JR, Feehery GR, Cheng X, Pradhan S.
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| Nat Struct Mol Biol 18(1):42-8. Epub 2010 Dec 12.
2011
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| 29 | DNMT1
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| Rapid and transient recruitment of DNMT1 to DNA double-strand breaks is mediated by its interaction with multiple components of the DNA damage response machinery.
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| Ha K, Lee GE, Palii SS, Brown KD, Takeda Y, Liu K, Bhalla KN, Robertson KD.
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| Hum Mol Genet 20(1):126-40. Epub 2010 Oct 11.
2011
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| 30 | DNMT1, UHRF1, USP7
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| Usp7 and Uhrf1 control ubiquitination and stability of the maintenance DNA methyltransferase Dnmt1.
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| Qin W, Leonhardt H, Spada F.
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| J Cell Biochem 112(2):439-44. doi: 10.1002/jcb.22998.
2011
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| 31 | DNMT1
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| DNA methyltransferase 1, cytosine methylation, and cytosine hydroxymethylation in mammalian mitochondria.
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| Shock LS, Thakkar PV, Peterson EJ, Moran RG, Taylor SM.
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| Proc Natl Acad Sci U S A 108(9):3630-5. Epub 2011 Feb 14.
2011
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| 32 | CDK1, CDK2, CDK5, DNMT1
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| Phosphorylation of human DNMT1: implication of cyclin-dependent kinases.
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| Lavoie G, St-Pierre Y.
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| Biochem Biophys Res Commun 409(2):187-92. Epub 2011 May 1.
2011
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| 33 | DNMT1
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| DNMT1 deficiency triggers mismatch repair defects in human cells through depletion of repair protein levels in a process involving the DNA damage response.
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| Loughery JE, Dunne PD, O'Neill KM, Meehan RR, McDaid JR, Walsh CP.
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| Hum Mol Genet 20(16):3241-55. Epub 2011 Jun 2.
2011
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| 34 | DNMT1, UHRF1, USP7
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| The USP7/Dnmt1 complex stimulates the DNA methylation activity of Dnmt1 and regulates the stability of UHRF1.
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| Felle M, Joppien S, Németh A, Diermeier S, Thalhammer V, Dobner T, Kremmer E, Kappler R, Längst G.
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| Nucleic Acids Res 39(19):8355-65. doi: 10.1093/nar/gkr528. Epub 2011 Jul 10.
2011
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| 35 | AR, DNMT1
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| Repression of androgen receptor transcription through the E2F1/DNMT1 axis.
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| Valdez CD, Davis JN, Odeh HM, Layfield TL, Cousineau CS, Berton TR, Johnson DG, Wojno KJ, Day ML.
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| PLoS One 6(9):e25187. doi: 10.1371/journal.pone.0025187. Epub 2011 Sep 26.
2011
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| 36 | DNMT1, SIRT1
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| SIRT1 deacetylates the DNA methyltransferase 1 (DNMT1) protein and alters its activities.
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| Peng L, Yuan Z, Ling H, Fukasawa K, Robertson K, Olashaw N, Koomen J, Chen J, Lane WS, Seto E.
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| Mol Cell Biol 31(23):4720-34. doi: 10.1128/MCB.06147-11. Epub 2011 Sep 26.
2011
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| 37 | DNMT1, UHRF1
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| DNMT1 maintains progenitor function in self-renewing somatic tissue.
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| Sen GL, Reuter JA, Webster DE, Zhu L, Khavari PA.
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| Nature 463(7280):563-7. Epub 2010 Jan 17.PMID: 20081831 2010
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| 38 | DNMT1, DNMT3L
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| DNA methylation-mediated down-regulation of DNA methyltransferase-1 (DNMT1) is coincident with, but not essential for, global hypomethylation in human placenta.
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| Novakovic B, Wong NC, Sibson M, Ng HK, Morley R, Manuelpillai U, Down T, Rakyan VK, Beck S, Hiendleder S, Roberts CT, Craig JM, Saffery R.
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| J Biol Chem 285(13):9583-93. Epub 2010 Jan 13. 2010
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| 39 | DNMT1, DNMT3A
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| Dnmt1 and Dnmt3a maintain DNA methylation and regulate synaptic function in adult forebrain neurons.
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| Feng J, Zhou Y, Campbell SL, Le T, Li E, Sweatt JD, Silva AJ, Fan G.
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| Nat Neurosci. 13(4):423-30. 2010
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| 40 | DDX53, DNMT1
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| Cancer/testis antigen CAGE exerts negative regulation on p53 expression through HDAC2 and confers resistance to anti-cancer drugs.
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| Kim Y, Park H, Park D, Lee YS, Choe J, Hahn JH, Lee H, Kim YM, Jeoung D.
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| J Biol Chem 285(34):25957-68. Epub 2010 Jun 8. 2010
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| 41 | DMAP1, DNMT1
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| DNA methyltransferase 1-associated protein (DMAP1) is a co-repressor that stimulates DNA methylation globally and locally at sites of double strand break repair.
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| Lee GE, Kim JH, Taylor M, Muller MT.
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| J Biol Chem 285(48):37630-40. Epub 2010 Sep 23. 2010
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| 42 | DNMT1, NAA10
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| hNaa10p contributes to tumorigenesis by facilitating DNMT1-mediated tumor suppressor gene silencing.
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| Lee CF, Ou DS, Lee SB, Chang LH, Lin RK, Li YS, Upadhyay AK, Cheng X, Wang YC, Hsu HS, Hsiao M, Wu CW, Juan LJ.
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| J Clin Invest 120(8):2920-30. doi: 10.1172/JCI42275. Epub 2010 Jul 1.
2010
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| 43 | DNMT1, KDM1A
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| The lysine demethylase LSD1 (KDM1) is required for maintenance of global DNA methylation.
|
| Wang J, Hevi S, Kurash JK, Lei H, Gay F, Bajko J, Su H, Sun W, Chang H, Xu G, Gaudet F, Li E, Chen T.
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| Nat Genet 41(1):125-9. Epub 2008 Dec 21. 2009
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| 44 | CDKN1A, DNMT1, EP300
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| p21(WAF1) negatively regulates DNMT1 expression in mammalian cells.
|
| Tan HH, Porter AG.
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| Biochem Biophys Res Commun 382(1):171-6. Epub 2009 Mar 9.
2009
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| 45 | DNMT1, HDAC1, KAT5, UHRF1
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| UHRF1 recruits the histone acetyltransferase Tip60 and controls its expression and activity.
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| Achour M, Fuhrmann G, Alhosin M, Rondé P, Chataigneau T, Mousli M, Schini-Kerth VB, Bronner C.
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| Biochem Biophys Res Commun 390(3):523-8. Epub 2009 Oct 2.PMID: 19800870 2009
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| 46 | DNMT1
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| SUMOylation enhances DNA methyltransferase 1 activity.
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| Lee B, Muller MT.
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| Biochem J. 421(3):449-61. 2009
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| 47 | DNMT1
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| DNA hypomethylation restricted to the murine forebrain induces cortical degeneration and impairs postnatal neuronal maturation.
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| Hutnick LK, Golshani P, Namihira M, Xue Z, Matynia A, Yang XW, Silva AJ, Schweizer FE, Fan G.
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| Hum Mol Genet. 18(15):2875-88. 2009
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| 48 | DNMT1
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| DNA (cytosine-5)-methyltransferase 1 as a mediator of mutant p53-determined p16(ink4A) down-regulation.
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| Guo Z, Tsai MH, Shiao YH, Chen LH, Wei ML, Lv X, Gius D, Little JB, Mitchell JB, Chuang EY.
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| J Biomed Sci 15(2):163-8. Epub 2007 Nov 24. 2008
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| 49 | DNMT1, HESX1
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| DNMT1 interacts with the developmental transcriptional repressor HESX1.
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| Sajedi E, Gaston-Massuet C, Andoniadou CL, Signore M, Hurd PJ, Dattani M, Martinez-Barbera JP.
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| Biochim Biophys Acta 1783(1):131-43. Epub 2007 Sep 7. 2008
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| 50 | CXXC1, DNMT1
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| CFP1 interacts with DNMT1 independently of association with the Setd1 Histone H3K4 methyltransferase complexes.
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| Butler JS, Lee JH, Skalnik DG.
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| DNA Cell Biol 27(10):533-43.PMID: 18680430 2008
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| 51 | DNMT1
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| The interaction of the SRA domain of ICBP90 with a novel domain of DNMT1 is involved in the regulation of VEGF gene expression.
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| Achour M, Jacq X, Rondé P, Alhosin M, Charlot C, Chataigneau T, Jeanblanc M, Macaluso M, Giordano A, Hughes AD, Schini-Kerth VB, Bronner C.
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| Oncogene. 27(15):2187-97. 2008
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| 52 | DNMT1
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| DNA methyltransferase 1 and 3B activate BAG-1 expression via recruitment of CTCFL/BORIS and modulation of promoter histone methylation.
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| Sun L, Huang L, Nguyen P, Bisht KS, Bar-Sela G, Ho AS, Bradbury CM, Yu W, Cui H, Lee S, Trepel JB, Feinberg AP, Gius D.
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| Cancer Res. 68(8):2726-35. 2008
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| 53 | DNMT1
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| CXXC domain of human DNMT1 is essential for enzymatic activity.
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| Pradhan M, Estève PO, Chin HG, Samaranayke M, Kim GD, Pradhan S.
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| Biochemistry 47(38):10000-9. Epub 2008 Aug 29.
2008
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| 54 | DNMT1
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| Complete inactivation of DNMT1 leads to mitotic catastrophe in human cancer cells.
|
| Chen T, Hevi S, Gay F, Tsujimoto N, He T, Zhang B, Ueda Y, Li E.
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| Nat Genet 39(3):391-6. Epub 2007 Feb 18. 2007
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| 55 | CBX5, DNMT1
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| Functional cooperation between HP1 and DNMT1 mediates gene silencing.
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| Smallwood A, Estève PO, Pradhan S, Carey M.
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| Genes Dev 21(10):1169-78. Epub 2007 Apr 30.PMID: 17470536 2007
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| 56 | DNMT1
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| Identification of DNMT1 (DNA methyltransferase 1) hypomorphs in somatic knockouts suggests an essential role for DNMT1 in cell survival.
|
| Egger G, Jeong S, Escobar SG, Cortez CC, Li TW, Saito Y, Yoo CB, Jones PA, Liang G.
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| Proc Natl Acad Sci U S A 103(38):14080-5. Epub 2006 Sep 8. 2006
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| 57 | HDAC1, STAT3, PTPN6, DNMT1
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| STAT3- and DNA methyltransferase 1-mediated epigenetic silencing of SHP-1 tyrosine phosphatase tumor suppressor gene in malignant T lymphocytes.
|
| Zhang Q, Wang HY, Marzec M, Raghunath PN, Nagasawa T, Wasik MA.
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| Proc Natl Acad Sci U S A 102(19):6948-53. Epub 2005 May 3. 2005
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| 58 | DNMT1, DNMT3B, XIST
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| XIST repression in the absence of DNMT1 and DNMT3B.
|
| Vasques LR, Stabellini R, Xue F, Tian XC, Soukoyan M, Pereira LV.
|
| DNA Res 12(5):373-8. Epub 2006 Jan 11.
2005
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| 59 | GAD1, DNMT1, RELN
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| DNA-methyltransferase 1 mRNA is selectively overexpressed in telencephalic GABAergic interneurons of schizophrenia brains.
|
| Veldic M, Caruncho HJ, Liu WS, Davis J, Satta R, Grayson DR, Guidotti A, Costa E.
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| Proc Natl Acad Sci U S A 101(1):348-53. Epub 2003 Dec 18. 2004
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| 60 | DNMT1
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| Mismatch repair genes identified using genetic screens in Blm-deficient embryonic stem cells.
|
| Guo G, Wang W, Bradley A.
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| Nature 429(6994):891-5. 2004
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| 61 | DNMT1
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| Human DNA methyltransferase 1 is required for maintenance of the histone H3 modification pattern.
|
| Espada J, Ballestar E, Fraga MF, Villar-Garea A, Juarranz A, Stockert JC, Robertson KD, Fuks F, Esteller M.
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| J Biol Chem 279(35):37175-84. Epub 2004 Jun 25. 2004
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| 62 | DNMT1, DNMT3B, DNMT3A
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| Effects of chromatin structure on the enzymatic and DNA binding functions of DNA methyltransferases DNMT1 and Dnmt3a in vitro.
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| Robertson AK, Geiman TM, Sankpal UT, Hager GL, Robertson KD.
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| Biochem Biophys Res Commun 322(1):110-8. 2004
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| 63 | DNMT1
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| Association analyses of DNA methyltransferase-1 (DNMT1) polymorphisms with systemic lupus erythematosus.
|
| Park BL, Kim LH, Shin HD, Park YW, Uhm WS, Bae SC.
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| J Hum Genet 49(11):642-6. Epub 2004 Sep 16. 2004
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| 64 | DNMT1
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| RGS6 interacts with DMAP1 and DNMT1 and inhibits DMAP1 transcriptional repressor activity.
|
| Liu Z, Fisher RA.
|
| J Biol Chem. 279(14):14120-8. 2004
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| 65 | DNMT1
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| DNMT1 is required to maintain CpG methylation and aberrant gene silencing in human cancer cells.
|
| Robert MF, Morin S, Beaulieu N, Gauthier F, Chute IC, Barsalou A, MacLeod AR.
|
| Nat Genet 33(1):61-5. 2003
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| 66 | ATRX, DNMT1, DNMT3B, HDAC1, HDAC2, KAT2B, KAT8, MBD1, MBD2, MECP2, SIN3A
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| Analysis of mammalian proteins involved in chromatin modification reveals new metaphase centromeric proteins and distinct chromosomal distribution patterns.
|
| Craig JM, Earle E, Canham P, Wong LH, Anderson M, Choo KH.
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| Hum Mol Genet 12(23):3109-21. Epub 2003 Sep 30. 2003
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| 67 | DNMT1
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| The DNA methyltransferases associate with HP1 and the SUV39H1 histone methyltransferase.
|
| Fuks F, Hurd PJ, Deplus R, Kouzarides T.
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| Nucleic Acids Res. 31(9):2305-12. 2003
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| 68 | DNMT1
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| Methyl-CpG-binding protein, MeCP2, is a target molecule for maintenance DNA methyltransferase, Dnmt1.
|
| Kimura H, Shiota K.
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| J Biol Chem. 278(7):4806-12. 2003
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| 69 | DNMT1
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| Induction of tumors in mice by genomic hypomethylation.
|
| Gaudet F, Hodgson JG, Eden A, Jackson-Grusby L, Dausman J, Gray JW, Leonhardt H, Jaenisch R.
|
| Science. 300(5618):489-92. 2003
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| 70 | DNMT1, DNMT3A
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| Dnmt3a and Dnmt1 functionally cooperate during de novo methylation of DNA.
|
| Fatemi M, Hermann A, Gowher H, Jeltsch A.
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| Eur J Biochem 269(20):4981-4. 2002
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| 71 | DNMT1
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| Co-operation and communication between the human maintenance and de novo DNA (cytosine-5) methyltransferases.
|
| Kim GD, Ni J, Kelesoglu N, Roberts RJ, Pradhan S.
|
| EMBO J. 21(15):4183-95. 2002
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| 72 | DNMT1, RB1
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| The retinoblastoma gene product interacts with maintenance human DNA (cytosine-5) methyltransferase and modulates its activity.
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| Pradhan S, Kim GD.
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| EMBO J. 21(4):779-88. 2002
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| 73 | DNMT1
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| DNA methyltransferase deficiency modifies cancer susceptibility in mice lacking DNA mismatch repair.
|
| Trinh BN, Long TI, Nickel AE, Shibata D, Laird PW.
|
| Mol Cell Biol. 22(9):2906-17. 2002
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| 74 | DNMT1
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| Dnmt1 overexpression causes genomic hypermethylation, loss of imprinting, and embryonic lethality.
|
| Biniszkiewicz D, Gribnau J, Ramsahoye B, Gaudet F, Eggan K, Humpherys D, Mastrangelo MA, Jun Z, Walter J, Jaenisch R.
|
| Mol Cell Biol. 22(7):2124-35. 2002
|
| 75 | DNMT1, DNMT3B
|
| Expression of DNA methyltransferases DNMT1, 3A, and 3B in normal hematopoiesis and in acute and chronic myelogenous leukemia.
|
| Mizuno S, Chijiwa T, Okamura T, Akashi K, Fukumaki Y, Niho Y, Sasaki H.
|
| Blood 97(5):1172-9. 2001
|
| 76 | DNMT1
|
| A critical role for Dnmt1 and DNA methylation in T cell development, function, and survival.
|
| Lee PP, Fitzpatrick DR, Beard C, Jessup HK, Lehar S, Makar KW, Pérez-Melgosa M, Sweetser MT, Schlissel MS, Nguyen S, Cherry SR, Tsai JH, Tucker SM, Weaver WM, Kelso A, Jaenisch R, Wilson CB.
|
| Immunity. 15(5):763-74. 2001
|
| 77 | DNMT1, TRDMT1
|
| Allele-specific variation in the gene copy number of human cytosine 5-methyltransferase.
|
| Franchina M, Kay PH.
|
| Hum Hered 50(2):112-7. 2000
|
| 78 | DNMT1
|
| Transcriptional regulation of the human DNA Methyltransferase (dnmt1) gene.
|
| Bigey P, Ramchandani S, Theberge J, Araujo FD, Szyf M.
|
| Gene 242(1-2):407-18. 2000
|
| 79 | DMAP1, DNMT1, HDAC2
|
| DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci.
|
| Rountree MR, Bachman KE, Baylin SB.
|
| Nat Genet 25(3):269-77. 2000
|
| 80 | DNMT1, E2F1
|
| DNMT1 forms a complex with Rb, E2F1 and HDAC1 and represses transcription from E2F-responsive promoters.
|
| Robertson KD, Ait-Si-Ali S, Yokochi T, Wade PA, Jones PL, Wolffe AP.
|
| Nat Genet 25(3):338-42. 2000
|
| 81 | DNMT1
|
| MBD2-MBD3 complex binds to hemi-methylated DNA and forms a complex containing DNMT1 at the replication foci in late S phase.
|
| Tatematsu KI, Yamazaki T, Ishikawa F.
|
| Genes Cells. 5(8):677-88. 2000
|
| 82 | DNMT1
|
| Identification of initiation sites for DNA replication in the human dnmt1 (DNA-methyltransferase) locus.
|
| Araujo FD, et al.
|
| J Biol Chem 274(14):9335-41. 1999
|
| 83 | DNMT1, DNMT3A, DNMT3B
|
| The human DNA methyltransferases (DNMTs) 1, 3a and 3b: coordinate mRNA expression in normal tissues and overexpression in tumors.
|
| Robertson KD, et al.
|
| Nucleic Acids Res 27(11):2291-8 1999
|
| 84 | DNMT1
|
| Two major forms of DNA (cytosine-5) methyltransferase in human somatic tissues.
|
| Hsu DW, et al.
|
| Proc Natl Acad Sci U S A 96(17):9751-6 1999
|
| 85 | DNMT1, DNMT3A, DNMT3B
|
| Cloning and characterization of a family of novel mammalian DNA (cytosine-5) methyltransferases.
|
| Okano, M.; Xie, S.; Li, E.
|
| Nat Genet 19(3):219-20. No abstract available 1998
|
| 86 | DNMT1
|
| Human DNA-(cytosine-5) methyltransferase-PCNA complex as a target for p21WAF1.
|
| Chuang LS, et al.
|
| Science 277(5334):1996-2000 1997
|
| 87 | DNMT1
|
| Human chromosome 19p : a fluorescence in situ hybridization map with genomic distance estimates for 79 intervals spanning 20 Mb.
|
| Brandriff BF, et al.
|
| Genomics 23 : 582-591. 1994
|
| 88 | DNMT1
|
| Isolation and characterization of the cDNA encoding human DNA methyltransferase.
|
| Yen RWC, et al.
|
| Nucleic Acids Res 20 : 2287-2291. 1992
|
| 89 | DNMT1
|
| A targeting sequence directs DNA methyltransferase to sites of DNA replication in mammalian nuclei.
|
| Leonhardt H, et al.
|
| Cell 71(5):865-73 1992
|
| 90 | DNMT1
|
| Targeted mutation of the DNA methyltransferase gene results in embryonic lethality.
|
| Li E, Bestor TH, Jaenisch R.
|
| Cell. 69(6):915-26. 1992
|
| 91 | DNMT1
|
| High expression of the DNA methyltransferase gene characterizes human neoplastic cells and progression stages of colon cancer.
|
| El-Deiry WS, et al.
|
| Proc Natl Acad Sci U S A 88 : 3470-3474. 1991
|
| 92 | DNMT1, TRDMT1, DNMT3A, DNMT3B
|
| Predictive motifs derived from cytosine methyltransferases.
|
| Posfai J, et al.
|
| Nucleic Acids Res 17(7):2421-35 1989
|
| 93 | DNMT1
|
| Cloning and sequencing of a cDNA encoding DNA methyltransferase of mouse cells. The carboxyl-terminal domain of the mammalian enzymes is related to bacterial restriction methyltransferases.
|
| Bestor T, et al.
|
| J Mol Biol 203 : 971-983. 1988
|