Citations for
1DNM2, NME1, NME2
Metastasis Suppressors NME1 and NME2 Promote Dynamin 2 Oligomerization and Regulate Tumor Cell Endocytosis, Motility, and Metastasis.
Khan I, Gril B, Steeg PS.
Cancer Res. Sep 15;79(18):4689-4702. doi: 10.1158/0008-5472.CAN-19-0492. Epub 2019 Jul 16. 2019
2ATG9A, DNM2, SNX18
SNX18 regulates ATG9A trafficking from recycling endosomes by recruiting Dynamin-2
Søreng K, Munson MJ, Lamb CA, Bjørndal GT, Pankiv S, Carlsson SR, Tooze SA, Simonsen A.
EMBO Rep. Apr;19(4):e44837. doi: 10.15252/embr.201744837. Epub 2018 Feb 7. 2018
3DNM2, IKZF1
Targeting High Dynamin-2 (DNM2) Expression by Restoring Ikaros Function in Acute Lymphoblastic Leukemia.
Ge Z, Gu Y, Han Q, Zhao G, Li M, Li J, Chen B, Sun T, Dovat S, Gale RP, Song C.
Sci Rep 6:38004. doi: 10.1038/srep38004. 2016
4CNM2, DNM2
Clinical, Electrophysiology, and Pathology Features of Dynamin Centronuclear Myopathy: A Case Report and Review of Literature.
Verma S, Balasubramanian SB.
J Clin Neuromuscul Dis 18(2):84-88. 2016
5DNM1, DNM2
Dynamin 2 is essential for mammalian spermatogenesis.
Redgrove KA, Bernstein IR, Pye VJ, Mihalas BP, Sutherland JM, Nixon B, McCluskey A, Robinson PJ, Holt JE, McLaughlin EA.
Sci Rep 6:35084. doi: 10.1038/srep35084. 2016
6CNM2, DNM2
Clinical, pathological and genetic characteristics of autosomal dominant inherited dynamin 2 centronuclear myopathy.
Liu X, Wu H, Gong J, Wang T, Yan C.
Mol Med Rep 13(5):4273-8. doi: 10.3892/mmr.2016.5047. 2016
7DNM2
Dynamin-2 is a novel NOS1β interacting protein and negative regulator in the collecting duct.
Hyndman KA, Arguello AM, Morsing SK, Pollock JS.
Am J Physiol Regul Integr Comp Physiol 310(7):R570-7. doi: 10.1152/ajpregu.00008.2015. 2016
8DNM2, MIB1, SNX18
Mib1 modulates dynamin 2 recruitment via Snx18 to promote Dll1 endocytosis for efficient Notch signaling.
Okano M, Matsuo H, Nishimura Y, Hozumi K, Yoshioka S, Tonoki A, Itoh M.
Genes Cells. May;21(5):425-41. doi: 10.1111/gtc.12350. Epub 2016 Feb 28. 2016
9DNM2, SPG69
Adult-onset autosomal dominant spastic paraplegia linked to a GTPase-effector domain mutation of dynamin 2.
Sambuughin N, Goldfarb LG, Sivtseva TM, Davydova TK, Vladimirtsev VA, Osakovskiy VL, Danilova AP, Nikitina RS, Ylakhova AN, Diachkovskaya MP, Sundborger AC, Renwick NM, Platonov FA, Hinshaw JE, Toro C.
BMC Neurol 15:223. doi: 10.1186/s12883-015-0481-3. 2015
10ARF6, DNM2, PSD3, PSD4
Activation of the Small G Protein Arf6 by Dynamin2 through Guanine Nucleotide Exchange Factors in Endocytosis.
Okada R, Yamauchi Y, Hongu T, Funakoshi Y, Ohbayashi N, Hasegawa H, Kanaho Y.
Sci Rep 5:14919. doi: 10.1038/srep14919. 2015
11DNM2
Dynamin 2 regulates biphasic insulin secretion and plasma glucose homeostasis.
Fan F, Ji C, Wu Y, Ferguson SM, Tamarina N, Philipson LH, Lou X.
J Clin Invest 125(11):4026-41. doi: 10.1172/JCI80652. 2015
12DNM2
Dynamin 2-dependent endocytosis is required for normal megakaryocyte development in mice.
Bender M, Giannini S, Grozovsky R, Jönsson T, Christensen H, Pluthero FG, Ko A, Mullally A, Kahr WH, Hoffmeister KM, Falet H.
Blood 125(6):1014-24. doi: 10.1182/blood-2014-07-587857. 2015
13DNM2, GJB2
Dynamin 2 interacts with connexin 26 to regulate its degradation and function in gap junction formation.
Xiao D, Chen S, Shao Q, Chen J, Bijian K, Laird DW, Alaoui-Jamali MA.
Int J Biochem Cell Biol 55:288-97. doi: 10.1016/j.biocel.2014.09.021. 2014
14DNM2
Reduction in dynamin-2 is implicated in ischaemic cardiac arrhythmias.
Shi D, Xie D, Zhang H, Zhao H, Huang J, Li C, Liu Y, Lv F, The E, Liu Y, Yuan T, Wang S, Chen J, Pan L, Yu Z, Liang D, Zhu W, Zhang Y, Li L, Peng L, Li J, Chen YH.
J Cell Mol Med 18(10):1992-9. doi: 10.1111/jcmm.12335. 2014
15DNM2, FGF1, FGF21, FGFR1
FGF21 promotes endothelial cell angiogenesis through a dynamin-2 and Rab5 dependent pathway.
Yaqoob U, Jagavelu K, Shergill U, de Assuncao T, Cao S, Shah VH.
PLoS One 9(5):e98130. doi: 10.1371/journal.pone.0098130. 2014
16DNM2
Dynamin2 organizes lamellipodial actin networks to orchestrate lamellar actomyosin.
Menon M, Askinazi OL, Schafer DA.
PLoS One 9(4):e94330. doi: 10.1371/journal.pone.0094330. 2014
17DNM1, DNM2, DNM3, TULP1
Protein partners of dynamin-1 in the retina.
Grossman GH, Ebke LA, Beight CD, Jang GF, Crabb JW, Hagstrom SA.
Vis Neurosci 30(4):129-39. doi: 10.1017/S0952523813000138. Epub 2013 Jun 10. 2013
18DNM1, DNM2, DNM3
Dynamin isoforms decode action potential firing for synaptic vesicle recycling.
Tanifuji S, Funakoshi-Tago M, Ueda F, Kasahara T, Mochida S.
J Biol Chem 288(26):19050-9. doi: 10.1074/jbc.M112.445874. Epub 2013 May 16. 2013
19DNM2, PQBP1
The XLID protein PQBP1 and the GTPase Dynamin 2 define a signaling link that orchestrates ciliary morphogenesis in postmitotic neurons.
Ikeuchi Y, de la Torre-Ubieta L, Matsuda T, Steen H, Okazawa H, Bonni A.
Cell Rep 4(5):879-89. doi: 10.1016/j.celrep.2013.07.042. Epub 2013 Aug 29. 2013
20AMPH, DNM2
Dual role of BAR domain-containing proteins in regulating vesicle release catalyzed by the GTPase, dynamin-2.
Neumann S, Schmid SL.
J Biol Chem 288(35):25119-28. doi: 10.1074/jbc.M113.490474. 2013
21CLTC, DNM2, SLC12A1
Dynamin2, clathrin, and lipid rafts mediate endocytosis of the apical Na/K/2Cl cotransporter NKCC2 in thick ascending limbs.
Ares GR, Ortiz PA.
J Biol Chem 287(45):37824-34. doi: 10.1074/jbc.M112.386425. Epub 2012 Sep 12. 2012
22CNM2, DNM2
Sporadic centronuclear myopathy with muscle pseudohypertrophy, neutropenia, and necklace fibres due to a DNM2 mutation.
Romero NB, Bevilacqua JA, Oldfors A, Fardeau M.
Neuromuscul Disord 21(2):148; author reply 148-9. No abstract available. 2011
23DNM2
The large GTPase dynamin2: a new player in connexin 43 gap junction endocytosis, recycling and degradation.
Gilleron J, Carette D, Fiorini C, Dompierre J, Macia E, Denizot JP, Segretain D, Pointis G.
Int J Biochem Cell Biol. 43(8):1208-17 2011
24DNM2, SH3KBP1
A Dyn2-CIN85 complex mediates degradative traffic of the EGFR by regulation of late endosomal budding.
Schroeder B, Weller SG, Chen J, Billadeau D, McNiven MA.
EMBO J 29(18):3039-53. Epub 2010 Aug 13.PMID: 20711168 2010
25CNM2, DNM2
Sporadic centronuclear myopathy with muscle pseudohypertrophy, neutropenia, and necklace fibers due to a DNM2 mutation.
Liewluck T, Lovell TL, Bite AV, Engel AG.
Neuromuscul Disord 20(12):801-4. 2010
26CNM2, DNM2
A centronuclear myopathy-dynamin 2 mutation impairs skeletal muscle structure and function in mice.
Durieux AC, Vignaud A, Prudhon B, Viou MT, Beuvin M, Vassilopoulos S, Fraysse B, Ferry A, Lainé J, Romero NB, Guicheney P, Bitoun M.
Hum Mol Genet 19(24):4820-36. Epub 2010 Sep 21. 2010
27DNM2
Dynamin 2 is required for actin assembly in phagocytosis in Sertoli cells.
Otsuka A, Abe T, Watanabe M, Yagisawa H, Takei K, Yamada H.
Biochem Biophys Res Commun 378(3):478-82. Epub 2008 Nov 24. 2009
28DNM2
Decrease of dynamin 2 levels in late-onset Alzheimer's disease alters Abeta metabolism.
Kamagata E, Kudo T, Kimura R, Tanimukai H, Morihara T, Sadik MG, Kamino K, Takeda M.
Biochem Biophys Res Commun 379(3):691-5. Epub 2009 Jan 4. 2009
29DNM2, FNBP1, WAS, WIPF1
FBP17 Mediates a Common Molecular Step in the Formation of Podosomes and Phagocytic Cups in Macrophages.
Tsuboi S, Takada H, Hara T, Mochizuki N, Funyu T, Saitoh H, Terayama Y, Yamaya K, Ohyama C, Nonoyama S, Ochs HD.
J Biol Chem 284(13):8548-56. Epub 2009 Jan 20. 2009
30DNM1, DNM2, DNM3
A possible effector role for the pleckstrin homology (PH) domain of dynamin.
Bethoney KA, King MC, Hinshaw JE, Ostap EM, Lemmon MA.
Proc Natl Acad Sci U S A 106(32):13359-64. Epub 2009 Aug 3.PMID: 19666604 2009
31CTTN, DNM2
Dynamin2 GTPase and cortactin remodel actin filaments.
Mooren OL, Kotova TI, Moore AJ, Schafer DA.
J Biol Chem 284(36):23995-4005. Epub 2009 Jul 15.PMID: 19605363 2009
32DNM2
Dynamin 2 gene is a novel susceptibility gene for late-onset Alzheimer disease in non-APOE-epsilon4 carriers.
Aidaralieva NJ, Kamino K, Kimura R, Yamamoto M, Morihara T, Kazui H, Hashimoto R, Tanaka T, Kudo T, Kida T, Okuda J, Uema T, Yamagata H, Miki T, Akatsu H, Kosaka K, Takeda M.
J Hum Genet 53(4):296-302. Epub 2008 Jan 31. 2008
33DICMT1, DNM2
Magnetic resonance imaging findings of leg musculature in Charcot-Marie-Tooth disease type 2 due to dynamin 2 mutation.
Gallardo E, Claeys KG, Nelis E, García A, Canga A, Combarros O, Timmerman V, De Jonghe P, Berciano J.
J Neurol 255(7):986-92. Epub 2008 Jun 17. 2008
34CPLX1, DNM2
Dynamin 2 associates with complexins and is found in the acrosomal region of mammalian sperm.
Zhao L, Shi X, Li L, Miller DJ.
Mol Reprod Dev 74(6):750-7. 2007
35DICMT1, DNM2
Two novel mutations in dynamin-2 cause axonal Charcot-Marie-Tooth disease.
Fabrizi GM, Ferrarini M, Cavallaro T, Cabrini I, Cerini R, Bertolasi L, Rizzuto N.
Neurology 69(3):291-5. 2007
36CNM2, DNM2
Dynamin 2 mutations cause sporadic centronuclear myopathy with neonatal onset.
Bitoun M, Bevilacqua JA, Prudhon B, Maugenre S, Taratuto AL, Monges S, Lubieniecki F, Cances C, Uro-Coste E, Mayer M, Fardeau M, Romero NB, Guicheney P.
Ann Neurol 62(6):666-70.PMID: 17932957 2007
37DNM2, FNBP1, SRGAP2,TRIP10
Coordination between the actin cytoskeleton and membrane deformation by a novel membrane tubulation domain of PCH proteins is involved in endocytosis.
Tsujita K, Suetsugu S, Sasaki N, Furutani M, Oikawa T, Takenawa T.
J Cell Biol 172(2):269-79. 2006
38DNM2
Complexes of syndapin II with dynamin II promote vesicle formation at the trans-Golgi network.
Kessels MM, Dong J, Leibig W, Westermann P, Qualmann B.
J Cell Sci 119(Pt 8):1504-16. Epub 2006 Mar 21. 2006
39DNM2
Differential regulation of interleukin 5-stimulated signaling pathways by dynamin.
Gorska MM, Cen O, Liang Q, Stafford SJ, Alam R.
J Biol Chem 281(20):14429-39. Epub 2006 Mar 23. 2006
40DNM1, DNM2
Domain requirements for an endocytosis-independent, isoform-specific function of dynamin-2.
Soulet F, Schmid SL, Damke H.
Exp Cell Res 312(18):3539-45. Epub 2006 Aug 1. 2006
41DNM2
Two mechanistically distinct forms of endocytosis in adrenal chromaffin cells: Differential effects of SH3 domains and amphiphysin antagonism.
Elhamdani A, Azizi F, Solomaha E, Palfrey HC, Artalejo CR.
FEBS Lett. 580(13):3263-9. 2006
42DICMT1, DNM2, ZSWIM4
Mutations in the pleckstrin homology domain of dynamin 2 cause dominant intermediate Charcot-Marie-Tooth disease.
Zuchner S, Noureddine M, Kennerson M, Verhoeven K, Claeys K, De Jonghe P, Merory J, Oliveira SA, Speer MC, Stenger JE, Walizada G, Zhu D, Pericak-Vance MA, Nicholson G, Timmerman V, Vance JM.
Nat Genet 37(3):289-94. Epub 2005 Jan 30. 2005
43DNM2, MYCN, CNM2
Mutations in dynamin 2 cause dominant centronuclear myopathy.
Bitoun M, Maugenre S, Jeannet PY, Lacene E, Ferrer X, Laforet P, Martin JJ, Laporte J, Lochmuller H, Beggs AH, Fardeau M, Eymard B, Romero NB, Guicheney P.
Nat Genet 37(11):1207-9. Epub 2005 Oct 16. 2005
44DNM2, VAV1
Dynamin 2 regulates T cell activation by controlling actin polymerization at the immunological synapse.
Gomez TS, Hamann MJ, McCarney S, Savoy DN, Lubking CM, Heldebrant MP, Labno CM, McKean DJ, McNiven MA, Burkhardt JK, Billadeau DD.
Nat Immunol 6(3):261-70. Epub 2005 Feb 6. 2005
45SNX9, DNM1, DNM2
SNX9 regulates dynamin assembly and is required for efficient clathrin-mediated endocytosis.
Soulet F, Yarar D, Leonard M, Schmid SL.
Mol Biol Cell 16(4):2058-67. Epub 2005 Feb 9. 2005
46DNM2
Regulated membrane recruitment of dynamin-2 mediated by sorting nexin 9.
Lundmark R, Carlsson SR.
J Biol Chem. 279(41):42694-702. 2004
47PFN1, DNM1, DNM2, CTTN
Dynamin2 and cortactin regulate actin assembly and filament organization.
Schafer DA, Weed SA, Binns D, Karginov AV, Parsons JT, Cooper JA.
Curr Biol 12(21):1852-7. 2002
48DNM2
Evidence that dynamin-2 functions as a signal-transducing GTPase.
Fish KN, Schmid SL, Damke H.
J Cell Biol. 150(1):145-54. 2000
49DNM2
Dynamin II is involved in endocytosis but not in the formation of transport vesicles from the trans-Golgi network.
Kasai K, Shin HW, Shinotsuka C, Murakami K, Nakayama K.
J Biochem. 125(4):780-9. 1999
50DNM2
Isolation of an ubiquitously expressed cDNA encoding human dynamin II, a member of the large GTP-binding protein family.
Diatloff-Zito C, Gordon AJ, Duchaud E, Merlin G.
Gene 163(2):301-6. 1995
51CNM1, MYF6, MTMR14, MTM1, DNM2
The myotubular myopathies: differential diagnosis of the X linked recessive, autosomal dominant, and autosomal recessive forms and present state of DNA studies.
Wallgren-Pettersson C, Clarke A, Samson F, Fardeau M, Dubowitz V, Moser H, Grimm T, Barohn RJ, Barth PG.
J Med Genet 32(9):673-9. Review. 1995