Citations for
1DNAJB6, HSPA4, SNCA
The molecular chaperones DNAJB6 and Hsp70 cooperate to suppress α-synuclein aggregation.
Aprile FA, Källstig E, Limorenko G, Vendruscolo M, Ron D, Hansen C.
Sci Rep 7(1):9039. doi: 10.1038/s41598-017-08324-z. 2017
2DNAJB6, LGMD1D
A novel DNAJB6 mutation causes dominantly inherited distal-onset myopathy and compromises DNAJB6 function.
Tsai PC, Tsai YS, Soong BW, Huang YH, Wu HT, Chen YH, Lin KP, Liao YC, Lee YC.
Clin Genet 92(2):150-157. doi: 10.1111/cge.13001. Epub 2017 Apr 12. 2017
3DNAJB6
The Short Isoform of DNAJB6 Protects against 1-Methyl-4-phenylpridinium Ion-Induced Apoptosis in LN18 Cells via Inhibiting Both ROS Formation and Mitochondrial Membrane Potential Loss.
Hong YM, Hong Y, Choi YG, Yeo S, Jin SH, Lee SW, Sung B, Lee SH, Jung H, Lim S.
Oxid Med Cell Longev 2017:7982389. doi: 10.1155/2017/7982389. Epub 2017 Feb 9. 2017
4DNAJB6
Emerging roles and underlying molecular mechanisms of DNAJB6 in cancer.
Meng E, Shevde LA, Samant RS.
Oncotarget 7(33):53984-53996. doi: 10.18632/oncotarget.9803. Review. 2016
5DNAJB6
The S/T-Rich Motif in the DNAJB6 Chaperone Delays Polyglutamine Aggregation and the Onset of Disease in a Mouse Model.
Kakkar V, Månsson C, de Mattos EP, Bergink S, van der Zwaag M, van Waarde MA, Kloosterhuis NJ, Melki R, van Cruchten RT, Al-Karadaghi S, Arosio P, Dobson CM, Knowles TP, Bates GP, van Deursen JM, Linse S, van de Sluis B, Emanuelsson C, Kampinga HH.
Mol Cell ol Cell. 2016 Apr 12. pii: S1097-2765(16)00227-6. doi: 10.1016/j.molcel.2016.03.017. [Epub ahead of print] 2016
6DNAJB6, LGMD1D
A novel mutation in DNAJB6, p.(Phe91Leu), in childhood-onset LGMD1D with a severe phenotype.
Nam TS, Li W, Heo SH, Lee KH, Cho A, Shin JH, Kim YO, Chae JH, Kim DS, Kim MK, Choi SY.
Neuromuscul Disord 25(11):843-51. doi: 10.1016/j.nmd.2015.08.002. Epub 2015 Aug 11. 2015
7DNAJB6
Nuclear Localization of DNAJB6 Is Associated With Survival of Patients With Esophageal Cancer and Reduces AKT Signaling and Proliferation of Cancer Cells.
Yu VZ, Wong VC, Dai W, Ko JM, Lam AK, Chan KW, Samant RS, Lung HL, Shuen WH, Law S, Chan YP, Lee NP, Tong DK, Law TT, Lee VH, Lung ML.
Gastroenterology 149(7):1825-1836.e5. doi: 10.1053/j.gastro.2015.08.025. Epub 2015 Aug 22. 2015
8DNAJB6, PLAUR
Heat shock proteins HSP70 and MRJ cooperatively regulate cell adhesion and migration through urokinase receptor.
Lin Y, Peng N, Zhuang H, Zhang D, Wang Y, Hua ZC.
BMC Cancer 14:639. doi: 10.1186/1471-2407-14-639. 2014
9DNAJB6
Myopathy-causing mutations in an HSP40 chaperone disrupt processing of specific client conformers.
Stein KC, Bengoechea R, Harms MB, Weihl CC, True HL.
J Biol Chem 289(30):21120-30. 2014
10DNAJB6
DNAJB6 is a peptide-binding chaperone which can suppress amyloid fibrillation of polyglutamine peptides at substoichiometric molar ratios.
Månsson C, Kakkar V, Monsellier E, Sourigues Y, Härmark J, Kampinga HH, Melki R, Emanuelsson C.
Cell Stress Chaperones 19(2):227-39. doi: 10.1007/s12192-013-0448-5. Epub 2013 Aug 1. 2014
11DNAJB6
DNAJB6 is a peptide-binding chaperone which can suppress amyloid fibrillation of polyglutamine peptides at substoichiometric molar ratios.
Månsson C, Kakkar V, Monsellier E, Sourigues Y, Härmark J, Kampinga HH, Melki R, Emanuelsson C.
Cell Stress Chaperones ell Stress Chaperones. 2013 Aug 1. [Epub ahead of print] 2013
12DNAJB6, LGMD1D
'Pathognomonic' muscle imaging findings in DNAJB6 mutated LGMD1D.
Sandell SM, Mahjneh I, Palmio J, Tasca G, Ricci E, Udd BA.
Eur J Neurol 20(12):1553-9. doi: 10.1111/ene.12239. Epub 2013 Jul 19. 2013
13DNAJB6, DNAJB8
The DNAJB6 and DNAJB8 protein chaperones prevent intracellular aggregation of polyglutamine peptides.
Gillis J, Schipper-Krom S, Juenemann K, Gruber A, Coolen S, van den Nieuwendijk R, van Veen H, Overkleeft H, Goedhart J, Kampinga HH, Reits EA.
J Biol Chem 288(24):17225-37. doi: 10.1074/jbc.M112.421685. Epub 2013 Apr 23. 2013
14DNAJB6, LGMD1D
DNAJB6 myopathy in an Asian cohort and cytoplasmic/nuclear inclusions.
Sato T, Hayashi YK, Oya Y, Kondo T, Sugie K, Kaneda D, Houzen H, Yabe I, Sasaki H, Noguchi S, Nonaka I, Osawa M, Nishino I.
Neuromuscul Disord 23(3):269-76. doi: 10.1016/j.nmd.2012.12.010. Epub 2013 Feb 6. 2013
15DKK1, DNAJB6, MSX1
DNAJB6 governs a novel regulatory loop determining Wnt/β-catenin signalling activity.
Menezes ME, Mitra A, Shevde LA, Samant RS.
Biochem J 444(3):573-80. doi: 10.1042/BJ20120205. 2012
16DNAJB6, LGMD1D
Exome sequencing reveals DNAJB6 mutations in dominantly-inherited myopathy.
Harms MB, Sommerville RB, Allred P, Bell S, Ma D, Cooper P, Lopate G, Pestronk A, Weihl CC, Baloh RH.
Ann Neurol 71(3):407-16. doi: 10.1002/ana.22683. Epub 2012 Feb 14. 2012
17DNAJB6, GSK3B, SPP1
DNAJB6 chaperones PP2A mediated dephosphorylation of GSK3β to downregulate β-catenin transcription target, osteopontin.
Mitra A, Menezes ME, Pannell LK, Mulekar MS, Honkanen RE, Shevde LA, Samant RS.
Oncogene 31(41):4472-83. doi: 10.1038/onc.2011.623. Epub 2012 Jan 23. 2012
18DNAJB6
Cell-cell adhesion defects in Mrj mutant trophoblast cells are associated with failure to pattern the chorion during early placental development.
Watson ED, Hughes M, Simmons DG, Natale DR, Sutherland AE, Cross JC.
Dev Dyn 240(11):2505-19. doi: 10.1002/dvdy.22755. Epub 2011 Oct 3. 2011
19DNAJB6, DNAJB8
A DNAJB chaperone subfamily with HDAC-dependent activities suppresses toxic protein aggregation.
Hageman J, Rujano MA, van Waarde MA, Kakkar V, Dirks RP, Govorukhina N, Oosterveld-Hut HM, Lubsen NH, Kampinga HH.
Mol Cell 37(3):355-69.PMID: 20159555 2010
20DNAJB6
DNAJB6 induces degradation of beta-catenin and causes partial reversal of mesenchymal phenotype.
Mitra A, Menezes ME, Shevde LA, Samant RS.
J Biol Chem 285(32):24686-94. Epub 2010 Jun 3.PMID: 20522561 2010
21DNAJB6
Cell cycle specific expression and nucleolar localization of human J-domain containing co-chaperone Mrj.
Dey S, Banerjee P, Saha P.
Mol Cell Biochem 322(1-2):137-42. Epub 2008 Nov 12.PMID: 19002655 2009
22DNAJB6
Structure of msj-1 gene in mice and humans: a possible role in the regulation of male reproduction.
Meccariello R, Berruti G, Chianese R, De Santis R, Di Cunto F, Scarpa D, Cobellis G, Zucchetti I, Pierantoni R, Altruda F, Fasano S.
Gen Comp Endocrinol 156(1):91-103. Epub 2007 Dec 4.PMID: 18184612 2008
23DNAJB6
The deubiquitinating enzyme mUBPy interacts with the sperm-specific molecular chaperone MSJ-1: the relation with the proteasome, acrosome, and centrosome in mouse male germ cells.
Berruti G, Martegani E.
Biol Reprod 72(1):14-21. Epub 2004 Sep 1.PMID: 15342353 2005
24DNAJB6
Characterization of a brain-enriched chaperone, MRJ, that inhibits Huntingtin aggregation and toxicity independently.
Chuang JZ, Zhou H, Zhu M, Li SH, Li XJ, Sung CH.
J Biol Chem 277(22):19831-8. 2002
25CFTR, CF, DNAJB6
The human DnaJ homologue (Hdj)-1/heat-shock protein (Hsp) 40 co-chaperone is required for the in vivo stabilization of the cystic fibrosis transmembrane conductance regulator by Hsp70.
Farinha CM, Nogueira P, Mendes F, Penque D, Amaral MD.
Biochem J 366(Pt 3):797-806. 2002
26DNAJA1, DNAJA2, DNAJA3, DNAJA4, DNAJB1, DNAJB11, DNAJB12, DNAJB2, DNAJB4, DNAJB5, DNAJB6, DNAJB8, DNAJB9, DNAJC1, DNAJC15, DNAJC17, DNAJC3, DNAJC4, DNAJC5, DNAJC6, DNAJC7, DNAJC8, DNAJC8P1, DNAJC9
Mammalian HSP40/DNAJ homologs: cloning of novel cDNAs and a proposal for their classification and nomenclature.
Ohtsuka K, Hata M.
Cell Stress Chaperones 5(2):98-112. 2000
27DNAJB6
Pituitary tumor-transforming gene protein associates with ribosomal protein S10and a novel human homologue of DnaJ in testicular cells.
Pei L.
J Biol Chem 274(5):3151-8. 1999
28DNAJB6
Cloning, tissue expression, and chromosomal assignment of human MRJ gene for amember of the DNAJ protein family.
Seki N, Hattori A, Hayashi A, Kozuma S, Miyajima N, Saito T.
J Hum Genet 44(3):185-9. 1999