1 | DNAJB6, HSPA4, SNCA
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| The molecular chaperones DNAJB6 and Hsp70 cooperate to suppress α-synuclein aggregation.
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| Aprile FA, Källstig E, Limorenko G, Vendruscolo M, Ron D, Hansen C.
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| Sci Rep 7(1):9039. doi: 10.1038/s41598-017-08324-z.
2017
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2 | DNAJB6, LGMD1D
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| A novel DNAJB6 mutation causes dominantly inherited distal-onset myopathy and compromises DNAJB6 function.
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| Tsai PC, Tsai YS, Soong BW, Huang YH, Wu HT, Chen YH, Lin KP, Liao YC, Lee YC.
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| Clin Genet 92(2):150-157. doi: 10.1111/cge.13001. Epub 2017 Apr 12.
2017
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3 | DNAJB6
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| The Short Isoform of DNAJB6 Protects against 1-Methyl-4-phenylpridinium Ion-Induced Apoptosis in LN18 Cells via Inhibiting Both ROS Formation and Mitochondrial Membrane Potential Loss.
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| Hong YM, Hong Y, Choi YG, Yeo S, Jin SH, Lee SW, Sung B, Lee SH, Jung H, Lim S.
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| Oxid Med Cell Longev 2017:7982389. doi: 10.1155/2017/7982389. Epub 2017 Feb 9.
2017
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4 | DNAJB6
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| Emerging roles and underlying molecular mechanisms of DNAJB6 in cancer.
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| Meng E, Shevde LA, Samant RS.
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| Oncotarget 7(33):53984-53996. doi: 10.18632/oncotarget.9803. Review.
2016
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5 | DNAJB6
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| The S/T-Rich Motif in the DNAJB6 Chaperone Delays Polyglutamine Aggregation and the Onset of Disease in a Mouse Model.
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| Kakkar V, Månsson C, de Mattos EP, Bergink S, van der Zwaag M, van Waarde MA, Kloosterhuis NJ, Melki R, van Cruchten RT, Al-Karadaghi S, Arosio P, Dobson CM, Knowles TP, Bates GP, van Deursen JM, Linse S, van de Sluis B, Emanuelsson C, Kampinga HH.
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| Mol Cell ol Cell. 2016 Apr 12. pii: S1097-2765(16)00227-6. doi: 10.1016/j.molcel.2016.03.017. [Epub ahead of print]
2016
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6 | DNAJB6, LGMD1D
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| A novel mutation in DNAJB6, p.(Phe91Leu), in childhood-onset LGMD1D with a severe phenotype.
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| Nam TS, Li W, Heo SH, Lee KH, Cho A, Shin JH, Kim YO, Chae JH, Kim DS, Kim MK, Choi SY.
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| Neuromuscul Disord 25(11):843-51. doi: 10.1016/j.nmd.2015.08.002. Epub 2015 Aug 11.
2015
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7 | DNAJB6
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| Nuclear Localization of DNAJB6 Is Associated With Survival of Patients With Esophageal Cancer and Reduces AKT Signaling and Proliferation of Cancer Cells.
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| Yu VZ, Wong VC, Dai W, Ko JM, Lam AK, Chan KW, Samant RS, Lung HL, Shuen WH, Law S, Chan YP, Lee NP, Tong DK, Law TT, Lee VH, Lung ML.
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| Gastroenterology 149(7):1825-1836.e5. doi: 10.1053/j.gastro.2015.08.025. Epub 2015 Aug 22.
2015
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8 | DNAJB6, PLAUR
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| Heat shock proteins HSP70 and MRJ cooperatively regulate cell adhesion and migration through urokinase receptor.
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| Lin Y, Peng N, Zhuang H, Zhang D, Wang Y, Hua ZC.
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| BMC Cancer 14:639. doi: 10.1186/1471-2407-14-639.
2014
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9 | DNAJB6
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| Myopathy-causing mutations in an HSP40 chaperone disrupt processing of specific client conformers.
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| Stein KC, Bengoechea R, Harms MB, Weihl CC, True HL.
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| J Biol Chem 289(30):21120-30.
2014
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10 | DNAJB6
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| DNAJB6 is a peptide-binding chaperone which can suppress amyloid fibrillation of polyglutamine peptides at substoichiometric molar ratios.
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| Månsson C, Kakkar V, Monsellier E, Sourigues Y, Härmark J, Kampinga HH, Melki R, Emanuelsson C.
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| Cell Stress Chaperones 19(2):227-39. doi: 10.1007/s12192-013-0448-5. Epub 2013 Aug 1.
2014
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11 | DNAJB6
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| DNAJB6 is a peptide-binding chaperone which can suppress amyloid fibrillation of polyglutamine peptides at substoichiometric molar ratios.
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| Månsson C, Kakkar V, Monsellier E, Sourigues Y, Härmark J, Kampinga HH, Melki R, Emanuelsson C.
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| Cell Stress Chaperones ell Stress Chaperones. 2013 Aug 1. [Epub ahead of print]
2013
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12 | DNAJB6, LGMD1D
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| 'Pathognomonic' muscle imaging findings in DNAJB6 mutated LGMD1D.
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| Sandell SM, Mahjneh I, Palmio J, Tasca G, Ricci E, Udd BA.
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| Eur J Neurol 20(12):1553-9. doi: 10.1111/ene.12239. Epub 2013 Jul 19.
2013
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13 | DNAJB6, DNAJB8
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| The DNAJB6 and DNAJB8 protein chaperones prevent intracellular aggregation of polyglutamine peptides.
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| Gillis J, Schipper-Krom S, Juenemann K, Gruber A, Coolen S, van den Nieuwendijk R, van Veen H, Overkleeft H, Goedhart J, Kampinga HH, Reits EA.
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| J Biol Chem 288(24):17225-37. doi: 10.1074/jbc.M112.421685. Epub 2013 Apr 23.
2013
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14 | DNAJB6, LGMD1D
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| DNAJB6 myopathy in an Asian cohort and cytoplasmic/nuclear inclusions.
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| Sato T, Hayashi YK, Oya Y, Kondo T, Sugie K, Kaneda D, Houzen H, Yabe I, Sasaki H, Noguchi S, Nonaka I, Osawa M, Nishino I.
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| Neuromuscul Disord 23(3):269-76. doi: 10.1016/j.nmd.2012.12.010. Epub 2013 Feb 6.
2013
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15 | DKK1, DNAJB6, MSX1
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| DNAJB6 governs a novel regulatory loop determining Wnt/β-catenin signalling activity.
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| Menezes ME, Mitra A, Shevde LA, Samant RS.
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| Biochem J 444(3):573-80. doi: 10.1042/BJ20120205.
2012
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16 | DNAJB6, LGMD1D
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| Exome sequencing reveals DNAJB6 mutations in dominantly-inherited myopathy.
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| Harms MB, Sommerville RB, Allred P, Bell S, Ma D, Cooper P, Lopate G, Pestronk A, Weihl CC, Baloh RH.
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| Ann Neurol 71(3):407-16. doi: 10.1002/ana.22683. Epub 2012 Feb 14.
2012
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17 | DNAJB6, GSK3B, SPP1
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| DNAJB6 chaperones PP2A mediated dephosphorylation of GSK3β to downregulate β-catenin transcription target, osteopontin.
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| Mitra A, Menezes ME, Pannell LK, Mulekar MS, Honkanen RE, Shevde LA, Samant RS.
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| Oncogene 31(41):4472-83. doi: 10.1038/onc.2011.623. Epub 2012 Jan 23.
2012
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18 | DNAJB6
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| Cell-cell adhesion defects in Mrj mutant trophoblast cells are associated with failure to pattern the chorion during early placental development.
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| Watson ED, Hughes M, Simmons DG, Natale DR, Sutherland AE, Cross JC.
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| Dev Dyn 240(11):2505-19. doi: 10.1002/dvdy.22755. Epub 2011 Oct 3.
2011
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19 | DNAJB6, DNAJB8
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| A DNAJB chaperone subfamily with HDAC-dependent activities suppresses toxic protein aggregation.
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| Hageman J, Rujano MA, van Waarde MA, Kakkar V, Dirks RP, Govorukhina N, Oosterveld-Hut HM, Lubsen NH, Kampinga HH.
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| Mol Cell 37(3):355-69.PMID: 20159555 2010
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20 | DNAJB6
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| DNAJB6 induces degradation of beta-catenin and causes partial reversal of mesenchymal phenotype.
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| Mitra A, Menezes ME, Shevde LA, Samant RS.
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| J Biol Chem 285(32):24686-94. Epub 2010 Jun 3.PMID: 20522561 2010
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21 | DNAJB6
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| Cell cycle specific expression and nucleolar localization of human J-domain containing co-chaperone Mrj.
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| Dey S, Banerjee P, Saha P.
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| Mol Cell Biochem 322(1-2):137-42. Epub 2008 Nov 12.PMID: 19002655 2009
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22 | DNAJB6
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| Structure of msj-1 gene in mice and humans: a possible role in the regulation of male reproduction.
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| Meccariello R, Berruti G, Chianese R, De Santis R, Di Cunto F, Scarpa D, Cobellis G, Zucchetti I, Pierantoni R, Altruda F, Fasano S.
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| Gen Comp Endocrinol 156(1):91-103. Epub 2007 Dec 4.PMID: 18184612 2008
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23 | DNAJB6
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| The deubiquitinating enzyme mUBPy interacts with the sperm-specific molecular chaperone MSJ-1: the relation with the proteasome, acrosome, and centrosome in mouse male germ cells.
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| Berruti G, Martegani E.
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| Biol Reprod 72(1):14-21. Epub 2004 Sep 1.PMID: 15342353 2005
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24 | DNAJB6
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| Characterization of a brain-enriched chaperone, MRJ, that inhibits Huntingtin aggregation and toxicity independently.
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| Chuang JZ, Zhou H, Zhu M, Li SH, Li XJ, Sung CH.
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| J Biol Chem 277(22):19831-8. 2002
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25 | CFTR, CF, DNAJB6
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| The human DnaJ homologue (Hdj)-1/heat-shock protein (Hsp) 40 co-chaperone is required for the in vivo stabilization of the cystic fibrosis transmembrane conductance regulator by Hsp70.
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| Farinha CM, Nogueira P, Mendes F, Penque D, Amaral MD.
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| Biochem J 366(Pt 3):797-806. 2002
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26 | DNAJA1, DNAJA2, DNAJA3, DNAJA4, DNAJB1, DNAJB11, DNAJB12, DNAJB2, DNAJB4, DNAJB5, DNAJB6, DNAJB8, DNAJB9, DNAJC1, DNAJC15, DNAJC17, DNAJC3, DNAJC4, DNAJC5, DNAJC6, DNAJC7, DNAJC8, DNAJC8P1, DNAJC9
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| Mammalian HSP40/DNAJ homologs: cloning of novel cDNAs and a proposal for their classification and nomenclature.
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| Ohtsuka K, Hata M.
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| Cell Stress Chaperones 5(2):98-112. 2000
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27 | DNAJB6
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| Pituitary tumor-transforming gene protein associates with ribosomal protein S10and a novel human homologue of DnaJ in testicular cells.
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| Pei L.
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| J Biol Chem 274(5):3151-8. 1999
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28 | DNAJB6
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| Cloning, tissue expression, and chromosomal assignment of human MRJ gene for amember of the DNAJ protein family.
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| Seki N, Hattori A, Hayashi A, Kozuma S, Miyajima N, Saito T.
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| J Hum Genet 44(3):185-9. 1999
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