| 1 | CBX5, DMRT2
|
| Heterochromatin protein 1α interacts with parallel RNA and DNA G-quadruplexes.
|
| Roach RJ, Garavís M, González C, Jameson GB, Filichev VV, Hale TK.
|
| Nucleic Acids Res 48(2):682-693. doi: 10.1093/nar/gkz1138.
2020
|
| 2 | ARNTL, DMRT2
|
| BMAL1 associates with chromosome ends to control rhythms in TERRA and telomeric heterochromatin.
|
| Park J, Zhu Q, Mirek E, Na L, Raduwan H, Anthony TG, Belden WJ.
|
| PLoS One 14(10):e0223803. doi: 10.1371/journal.pone.0223803. eCollection 2019.
2019
|
| 3 | DMRT2
|
| Expression and differential regulation of human TERRA at several chromosome ends.
|
| Feretzaki M, Renck Nunes P, Lingner J.
|
| RNA 25(11):1470-1480. doi: 10.1261/rna.072322.119. Epub 2019 Jul 26.
2019
|
| 4 | ATF7, DMRT2
|
| Telomere shortening by transgenerational transmission of TNF-α-induced TERRA via ATF7.
|
| Liu B, Maekawa T, Yoshida K, Ly NH, Inoue K, Hasegawa A, Chatton B, Ogura A, Ishii S.
|
| Nucleic Acids Res 47(1):283-298. doi: 10.1093/nar/gky1149.
2019
|
| 5 | DMRT2
|
| Homozygous DMRT2 variant associates with severe rib malformations in a newborn.
|
| Bouman A, Waisfisz Q, Admiraal J, van de Loo M, van Rijn RR, Micha D, Oostra RJ, Mathijssen IB.
|
| Am J Med Genet A 176(5):1216-1221. doi: 10.1002/ajmg.a.38668.
2018
|
| 6 | CTCF, DMRT2
|
| CTCF driven TERRA transcription facilitates completion of telomere DNA replication.
|
| Beishline K, Vladimirova O, Tutton S, Wang Z, Deng Z, Lieberman PM.
|
| Nat Commun 8(1):2114. doi: 10.1038/s41467-017-02212-w.
2017
|
| 7 | DMRT2, HSF1
|
| Heat shock factor 1 promotes TERRA transcription and telomere protection upon heat stress.
|
| Koskas S, Decottignies A, Dufour S, Pezet M, Verdel A, Vourc'h C, Faure V.
|
| Nucleic Acids Res 45(11):6321-6333. doi: 10.1093/nar/gkx208.
2017
|
| 8 | ATRX, DMRT2
|
| TERRA RNA Antagonizes ATRX and Protects Telomeres
|
| Chu HP, Cifuentes-Rojas C, Kesner B, Aeby E, Lee HG, Wei C, Oh HJ, Boukhali M, Haas W, Lee JT.
|
| Cell. Jun 29;170(1):86-101.e16. doi: 10.1016/j.cell.2017.06.017 2017
|
| 9 | DMRT2, MORF4L2
|
| Quantitative interaction screen of telomeric repeat-containing RNA reveals novel TERRA regulators.
|
| Scheibe M, Arnoult N, Kappei D, Buchholz F, Decottignies A, Butter F, Mann M.
|
| Genome Res 23(12):2149-57. doi: 10.1101/gr.151878.112. Epub 2013 Aug 6.
2013
|
| 10 | DMRT2
|
| Celf1 regulation of dmrt2a is required for somite symmetry and left-right patterning during zebrafish development.
|
| Matsui T, Sasaki A, Akazawa N, Otani H, Bessho Y.
|
| Development 139(19):3553-60. doi: 10.1242/dev.077263. Epub 2012 Aug 16.
2012
|
| 11 | DMRT2, HNRNPA1, POT1, RPA1
|
| TERRA and hnRNPA1 orchestrate an RPA-to-POT1 switch on telomeric single-stranded DNA.
|
| Flynn RL, Centore RC, O'Sullivan RJ, Rai R, Tse A, Songyang Z, Chang S, Karlseder J, Zou L.
|
| Nature 471(7339):532-6. Epub 2011 Mar 13.
2011
|
| 12 | DEL9P, DMRT1, DMRT2, DUP15QD, IGF1R, SRA2
|
| A de novo unbalanced translocation leading to partial monosomy 9p23-pter and partial trisomy 15q25.3-qter associated with 46,XY complete gonadal dysgenesis, tall stature and mental retardation.
|
| Argyriou L, Hiort O, Meinecke P, Wünsch L, Volleth M, Hinrichs F, Caliebe A, Gillessen-Kaesbach G.
|
| Clin Dysmorphol 19(4):190-4.PMID: 20671549 2010
|
| 13 | DMRT2
|
| The non-coding RNA TERRA is a natural ligand and direct inhibitor of human telomerase.
|
| Redon S, Reichenbach P, Lingner J.
|
| Nucleic Acids Res 38(17):5797-806. Epub 2010 May 11.PMID: 20460456 2010
|
| 14 | DMRT2
|
| Left-right function of dmrt2 genes is not conserved between zebrafish and mouse.
|
| Lourenço R, Lopes SS, Saúde L.
|
| PLoS One 5(12):e14438.
2010
|
| 15 | DMRT2, MYF5, PAX3
|
| A Pax3/Dmrt2/Myf5 regulatory cascade functions at the onset of myogenesis.
|
| Sato T, Rocancourt D, Marques L, Thorsteinsdóttir S, Buckingham M.
|
| PLoS Genet 6(4):e1000897.
2010
|
| 16 | DMRT2, PAX3
|
| Dmrt2 and Pax3 double-knockout mice show severe defects in embryonic myogenesis.
|
| Seo KW.
|
| Comp Med 57(5):460-8.
2007
|
| 17 | DMRT2, MYF5
|
| Targeted disruption of the DM domain containing transcription factor Dmrt2 reveals an essential role in somite patterning.
|
| Seo KW, Wang Y, Kokubo H, Kettlewell JR, Zarkower DA, Johnson RL.
|
| Dev Biol 290(1):200-10. Epub 2006 Jan 4.
2006
|
| 18 | SRA2, DMRT1, DMRT2
|
| Three patients with 9p deletions including DMRT1 and DMRT2: a girl with XY complement, bilateral ovotestes, and extreme growth retardation, and two XX females with normal pubertal development.
|
| Ounap K, Uibo O, Zordania R, Kiho L, Ilus T, Oiglane-Shlik E, Bartsch O.
|
| Am J Med Genet 130A(4):415-23. 2004
|
| 19 | DMRT1, DMRT2, DMRT3
|
| Genomic organization and expression of the doublesex-related gene cluster in vertebrates and detection of putative regulatory regions for dmrt1.
|
| Brunner B, Hornung U, Shan Z, Nanda I, Kondo M, Zend-Ajusch E, Haaf T, Ropers HH, Shima A, Schmid M, Kalscheuer VM, Schartl M.
|
| Genomics 77(1/2):8-17. 2001
|
| 20 | DMRT1, DMRT2
|
| The human doublesex-related gene, DMRT2, is homologous to a gene involved in somitogenesis and encodes a potential bicistronic transcript.
|
| Ottolenghi C, Veitia R, Barbieri M, Fellous M, McElreavey K.
|
| Genomics 64(2):179-86. 2000
|
| 21 | DMRT1, DMRT2, DMRT3, KANK1, SRA2
|
| The region on 9p associated with 46,XY sex reversal contains several transcripts expressed in the urogenital system and a novel doublesex-related domain.
|
| Ottolenghi C, Veitia R, Quintana-Murci L, Torchard D, Scapoli L, Souleyreau-Therville N, Beckmann J, Fellous M, McElreavey K.
|
| Genomics 64(2):170-8. 2000
|
| 22 | DMRT1, DMRT2, SRA2
|
| A new submicroscopic deletion that refines the 9p region for sex reversal.
|
| Calvari V, Bertini V, De Grandi A, Peverali G, Zuffardi O, Ferguson-Smith M, Knudtzon J, Camerino G, Borsani G, Guioli S.
|
| Genomics 65(3):203-12. 2000
|
| 23 | TDFA, DMRT1, DMRT2, SRA2
|
| Sex-determining gene(s) on distal 9p: clinical and molecular studies in six cases.
|
| Muroya K, Okuyama T, Goishi K, Ogiso Y, Fukuda S, Kameyama J, Sato H, Suzuki Y, Terasaki H, Gomyo H, Wakui K, Fukushima Y, Ogata T.
|
| J Clin Endocrinol Metab 85(9):3094-100. 2000
|
| 24 | DMRT1, DMRT2, SRA2,
|
| A region of human chromosome 9p required for testis development contains two genes related to known sexual regulators.
|
| Raymond CS, et al.
|
| Hum Mol Genet 8(6):989-96. 1999
|
| 25 | DMRT1, DMRT2, DMRT@
|
| Evidence for evolutionary conservation of sex-determining genes.
|
| Raymond CS, et al.
|
| Nature 391(6668):691-5. 1998
|