| 1 | DLX5, DLX6
|
| Posterior axis formation requires Dlx5/Dlx6 expression at the neural plate border.
|
| Narboux-Neme N, Ekker M, Levi G, Heude E.
|
| PLoS One 14(3):e0214063. doi: 10.1371/journal.pone.0214063. eCollection 2019.
2019
|
| 2 | DLX5, DLX6
|
| Measuring inputs to a common function: The case of Dlx5 and Dlx6.
|
| Quach A, MacKenzie RK, Bendall AJ.
|
| Biochem Biophys Res Commun 478(1):371-377. doi: 10.1016/j.bbrc.2016.07.044. Epub 2016 Jul 11.
2016
|
| 3 | DLX5, DLX6, SHFM1
|
| The apical ectodermal ridge of the mouse model of ectrodactyly Dlx5;Dlx6-/- shows altered stratification and cell polarity, which are restored by exogenous Wnt5a ligand.
|
| Conte D, Garaffo G, Lo Iacono N, Mantero S, Piccolo S, Cordenonsi M, Perez-Morga D, Orecchia V, Poli V, Merlo GR.
|
| Hum Mol Genet 25(4):740-54. doi: 10.1093/hmg/ddv514. Epub 2015 Dec 18.
2016
|
| 4 | DLX5, DLX6
|
| Dlx5 and Dlx6 control uterine adenogenesis during post-natal maturation: possible consequences for endometriosis.
|
| Bellessort B, Le Cardinal M, Bachelot A, Narboux-Nême N, Garagnani P, Pirazzini C, Barbieri O, Mastracci L, Jonchere V, Duvernois-Berthet E, Fontaine A, Alfama G, Levi G.
|
| Hum Mol Genet 25(1):97-108. doi: 10.1093/hmg/ddv452. Epub 2015 Oct 28.
2016
|
| 5 | DLX5, DLX6, SHFM1
|
| Absent expression of the osteoblast-specific maternally imprinted genes, DLX5 and DLX6, causes split hand/split foot malformation type I.
|
| Rattanasopha S, Tongkobpetch S, Srichomthong C, Kitidumrongsook P, Suphapeetiporn K, Shotelersuk V.
|
| J Med Genet 51(12):817-23. doi: 10.1136/jmedgenet-2014-102576.
2014
|
| 6 | DLX5, DLX6, DYNC1L1
|
| Next generation sequencing of chromosomal rearrangements in patients with split-hand/split-foot malformation provides evidence for DYNC1I1 exonic enhancers of DLX5/6 expression in humans.
|
| Lango Allen H, Caswell R, Xie W, Xu X, Wragg C, Turnpenny PD, Turner CL, Weedon MN, Ellard S.
|
| J Med Genet 51(4):264-7. doi: 10.1136/jmedgenet-2013-102142. Epub 2014 Jan 23.
2014
|
| 7 | DLX5, DLX6, MSX1, MSX2
|
| BMP-Mediated Functional Cooperation between Dlx5;Dlx6 and Msx1;Msx2 during Mammalian Limb Development.
|
| Vieux-Rochas M, Bouhali K, Mantero S, Garaffo G, Provero P, Astigiano S, Barbieri O, Caratozzolo MF, Tullo A, Guerrini L, Lallemand Y, Robert B, Levi G, Merlo GR.
|
| PLoS One 8(1):e51700. doi: 10.1371/journal.pone.0051700. Epub 2013 Jan 29.
2013
|
| 8 | DLX5, DLX6, EDN1
|
| Endothelin regulates neural crest deployment and fate to form great vessels through Dlx5/Dlx6-independent mechanisms.
|
| Kim KS, Arima Y, Kitazawa T, Nishiyama K, Asai R, Uchijima Y, Sato T, Levi G, Kitanaka S, Igarashi T, Kurihara Y, Kurihara H.
|
| Mech Dev ech Dev. 2013 Aug 8. doi:pii: S0925-4773(13)00060-9. 10.1016/j.mod.2013.07.005. [Epub ahead of print]
2013
|
| 9 | DLX5, DLX6, SHFM1
|
| Functional characterization of tissue-specific enhancers in the DLX5/6 locus.
|
| Birnbaum RY, Everman DB, Murphy KK, Gurrieri F, Schwartz CE, Ahituv N.
|
| Hum Mol Genet 21(22):4930-8. doi: 10.1093/hmg/dds336. Epub 2012 Aug 21.
2012
|
| 10 | DLX5, DLX6
|
| Dlx5 and Dlx6 expression in the anterior neural fold is essential for patterning the dorsal nasal capsule.
|
| Gitton Y, Benouaiche L, Vincent C, Heude E, Soulika M, Bouhali K, Couly G, Levi G.
|
| Development 138(5):897-903. doi: 10.1242/dev.057505. Epub 2011 Jan 26.
2011
|
| 11 | DEL7Q21, DLX5, DLX6
|
| Deletion of an enhancer near DLX5 and DLX6 in a family with hearing loss, craniofacial defects, and an inv(7)(q21.3q35).
|
| Brown KK, Reiss JA, Crow K, Ferguson HL, Kelly C, Fritzsch B, Morton CC.
|
| Hum Genet 127(1):19-31. Epub .PMID: 19707792 2010
|
| 12 | DLX5, DLX6, SHFM1
|
| Genome-wide profiling of p63 DNA-binding sites identifies an element that regulates gene expression during limb development in the 7q21 SHFM1 locus.
|
| Kouwenhoven EN, van Heeringen SJ, Tena JJ, Oti M, Dutilh BE, Alonso ME, de la Calle-Mustienes E, Smeenk L, Rinne T, Parsaulian L, Bolat E, Jurgelenaite R, Huynen MA, Hoischen A, Veltman JA, Brunner HG, Roscioli T, Oates E, Wilson M, Manzanares M, Gómez-Skarmeta JL, Stunnenberg HG, Lohrum M, van Bokhoven H, Zhou H.
|
| PLoS Genet 6(8):e1001065.PMID: 20808887 2010
|
| 13 | DLX5, DLX6
|
| Dlx5 and Dlx6 regulate the development of parvalbumin-expressing cortical interneurons.
|
| Wang Y, Dye CA, Sohal V, Long JE, Estrada RC, Roztocil T, Lufkin T, Deisseroth K, Baraban SC, Rubenstein JL.
|
| J Neurosci 30(15):5334-45.PMID: 20392955 2010
|
| 14 | DLX6
|
| Expression analysis and mutation detection of DLX5 and DLX6 in autism.
|
| Nakashima N, Yamagata T, Mori M, Kuwajima M, Suwa K, Momoi MY.
|
| Brain Dev 32(2):98-104. Epub 2009 Feb 4.PMID: 19195802 2010
|
| 15 | DLX5, DLX6
|
| Dlx5 Is a cell autonomous regulator of chondrocyte hypertrophy in mice and functionally substitutes for Dlx6 during endochondral ossification.
|
| Zhu H, Bendall AJ.
|
| PLoS One 4(11):e8097.PMID: 19956613 2009
|
| 16 | DLX5, DLX6
|
| Balanced gene regulation by an embryonic brain ncRNA is critical for adult hippocampal GABA circuitry.
|
| Bond AM, Vangompel MJ, Sametsky EA, Clark MF, Savage JC, Disterhoft JF, Kohtz JD.
|
| Nat Neurosci 12(8):1020-7. Epub 2009 Jul 20.PMID: 19620975 2009
|
| 17 | DEL7Q21, SHFM1, DLX5, DLX6
|
| Complex rearrangement of chromosomes 7q21.13-q22.1 confirms the ectrodactyly-deafness locus and suggests new candidate genes.
|
| Bernardini L, Palka C, Ceccarini C, Capalbo A, Bottillo I, Mingarelli R, Novelli A, Dallapiccola B.
|
| Am J Med Genet A 146(2):238-44. 2008
|
| 18 | DLX5, DLX6, SHFM1, SHFM4
|
| Regulation of Dlx5 and Dlx6 gene expression by p63 is involved in EEC and SHFM congenital limb defects.
|
| Lo Iacono N, Mantero S, Chiarelli A, Garcia E, Mills AA, Morasso MI, Costanzo A, Levi G, Guerrini L, Merlo GR.
|
| Development 135(7):1377-88.PMID: 18326838 2008
|
| 19 | SHFM1, DEL7Q21, DLX5, DLX6
|
| Characterization of a 16 Mb interstitial chromosome 7q21 deletion by tiling path array CGH.
|
| Tzschach A, Menzel C, Erdogan F, Schubert M, Hoeltzenbein M, Barbi G, Petzenhauser C, Ropers HH, Ullmann R, Kalscheuer V.
|
| Am J Med Genet A 143(4):333-7. 2007
|
| 20 | DLX5,DLX6,MECP2
|
| DLX5 and DLX6 Expression Is Biallelic and Not Modulated by MeCP2 Deficiency.
|
| Schule B, Li HH, Fisch-Kohl C, Purmann C, Francke U.
|
| Am J Hum Genet 81(3):492-506. Epub 2007 Aug 2. 2007
|
| 21 | DLX1,DLX2,DLX3,DLX4,DLX5,DLX6
|
| Dlx homeobox gene control of mammalian limb and craniofacial development.
|
| Kraus P, Lufkin T.
|
| Am J Med Genet A 140(13):1366-74. Review. 2006
|
| 22 | DEL7Q21,DLX5,DLX6,SHFM1
|
| The Dlx5 and Dlx6 homeobox genes are essential for craniofacial, axial, and appendicular skeletal development.
|
| Robledo RF, Rajan L, Li X, Lufkin T.
|
| Genes Dev 16(9):1089-101. 2002
|
| 23 | DLX6
|
| The coding region of the human DLX6 gene contains a polymorphic CAG/CCG repeat.
|
| Pfeffer U, Ferro P, Pavia V, Trombino S, Dell'Eva R, Merlo G, Levi G.
|
| Int J Oncol 18(6):1293-7. 2001
|
| 24 | DLX6,HAND2
|
| Role of Dlx6 in regulation of an endothelin-1-dependent, dHAND branchial arch enhancer.
|
| Charite J, McFadden DG, Merlo G, Levi G, Clouthier DE, Yanagisawa M, Richardson JA, Olson EN.
|
| Genes Dev 15(22):3039-49. 2001
|
| 25 | DLX5, DLX6, SHFM1, DEL7Q21
|
| Characterization of the split hand/split foot malformation locus SHFM1at 7q21.3-q22.1 and analysis of a candidate gene for its expression during limb development.
|
| Crackower MA, et al.
|
| Hum Mol Genet 5 : 571-579. 1996
|
| 26 | DLX1, DLX2, DLX5, DLX6
|
| Cloning and characterization of two members of the vertebrate Dlx gene family.
|
| Simeone A, et al.
|
| Proc Natl Acad Sci U S A 91 : 2250-2254. 1994
|