Citations for
1DLL3, SCODO1
Notch inhibition by the ligand DELTA-LIKE 3 defines the mechanism of abnormal vertebral segmentation in spondylocostal dysostosis.
Chapman G, Sparrow DB, Kremmer E, Dunwoodie SL.
Hum Mol Genet 20(5):905-16. Epub 2010 Dec 7. 2011
2DLL3, NOTCH1
Expression of Notch receptors, ligands and target genes during development of the mouse mammary gland.
Raafat A, Goldhar AS, Klauzinska M, Xu K, Amirjaz I, McCurdy D, Lashin K, Salomon D, Vonderhaar BK, Egan S, Callahan R.
J Cell Physiol Cell Physiol. 2010 Dec 6. [Epub ahead of print] 2010
3DLL3, HES7, LFNG, MESP2
The role of Notch in patterning the human vertebral column.
Dunwoodie SL.
Curr Opin Genet Dev 19(4):329-37. Epub 2009 Jul 14. 2009
4DLL3, HUWE1, MYCN, NOTCH1
The N-Myc-DLL3 cascade is suppressed by the ubiquitin ligase Huwe1 to inhibit proliferation and promote neurogenesis in the developing brain.
Zhao X, D' Arca D, Lim WK, Brahmachary M, Carro MS, Ludwig T, Cardo CC, Guillemot F, Aldape K, Califano A, Iavarone A, Lasorella A.
Dev Cell 17(2):210-21. 2009
5ASCL1, DLL3, NEUROG2
Ascl1 and Neurog2 form novel complexes and regulate Delta-like3 (Dll3) expression in the neural tube.
Henke RM, Meredith DM, Borromeo MD, Savage TK, Johnson JE.
Dev Biol 328(2):529-40. Epub 2009 Jan 14. 2009
6CFNS, DLL3, EFNB1, FOAR, FRNS, GPC3, LRP2, PAMD, SCDO1, SGBS, STRA6, UNK
Genetic aspects of human congenital diaphragmatic hernia.
Pober BR.
Clin Genet 74(1):1-15. Epub 2008 May 28. 2008
7DLL1, DLL3
The intracellular region of Notch ligands Dll1 and Dll3 regulates their trafficking and signaling activity.
Heuss SF, Ndiaye-Lobry D, Six EM, IsraŽl A, Logeat F.
Proc Natl Acad Sci U S A 105(32):11212-7. Epub 2008 Aug 1. 2008
8DLL1, DLL3
Divergent functions and distinct localization of the Notch ligands DLL1 and DLL3 in vivo.
Geffers I, Serth K, Chapman G, Jaekel R, Schuster-Gossler K, Cordes R, Sparrow DB, Kremmer E, Dunwoodie SL, Klein T, Gossler A.
J Cell Biol 178(3):465-76. 2007
9DLL3
DLL3 as a candidate gene for vertebral malformations.
Giampietro PF, Raggio CL, Reynolds C, Ghebranious N, Burmester JK, Glurich I, Rasmussen K, McPherson E, Pauli RM, Shukla SK, Merchant S, Jacobsen FS, Faciszewski T, Blank RD.
Am J Med Genet A 140(22):2447-53. 2006
10DLL3
Molecular analysis of congenital scoliosis: a candidate gene approach.
Maisenbacher MK, Han JS, O'brien ML, Tracy MR, Erol B, Schaffer AA, Dormans JP, Zackai EH, Kusumi K.
Hum Genet 116(5):416-9. Epub 2005 Feb 17. 2005
11DLL3, SCDO1
Pseudodominant inheritance of spondylocostal dysostosis type 1 caused by two familial delta-like 3 mutations.
Whittock NV, Ellard S, Duncan J, de Die-Smulders CE, Vles JS, Turnpenny PD.
Clin Genet 66(1):67-72. 2004
12CADASIL, DLL1, Dll3, DLL4, JAG1, JAG2, NOTCH1, NOTCH2, NOTCH3, NOTCH4 , RBPJ, SCDO1
Notch signaling and inherited disease syndromes.
Gridley T.
Hum Mol Genet 12 Spec No 1:R9-13. Review. 2003
13DLL3, SCDO1
Novel mutations in DLL3, a somitogenesis gene encoding a ligand for the Notch signalling pathway, cause a consistent pattern of abnormal vertebral segmentation in spondylocostal dysostosis.
Turnpenny PD, Whittock N, Duncan J, Dunwoodie S, Kusumi K, Ellard S.
J Med Genet 40(5):333-9. 2003
14DLL3, SCDO1
A cluster of autosomal recessive spondylocostal dysostosis caused by three newly identified DLL3 mutations segregating in a small village.
Bonafe L, Giunta C, Gassner M, Steinmann B, Superti-Furga A.
Clin Genet 64(1):28-35. 2003
15DLL3, SCDO1
Axial skeletal defects caused by mutation in the spondylocostal dysplasia/pudgy gene Dll3 are associated with disruption of the segmentation clock within the presomitic mesoderm.
Dunwoodie SL, Clements M, Sparrow DB, Sa X, Conlon RA, Beddington RS.
Development 129(7):1795-806. 2002
16DLL3, SCDO1
Mutations in the human delta homologue, DLL3, cause axial skeletal defects in spondylocostal dysostosis.
Bulman MP, Kusumi K, Frayling TM, McKeown C, Garrett C, Lander ES, Krumlauf R, Hattersley AT, Ellard S, Turnpenny PD.
Nat Genet 24(4):438-41. 2000
17DLL3, SCDO1
A gene for autosomal recessive spondylocostal dysostosis maps to 19q13.1-q13.3.
Turnpenny PD, Bulman MP, Frayling TM, Abu-Nasra TK, Garrett C, Hattersley AT, Ellard S.
Am J Hum Genet 65(1):175-82. 1999