| 1 | DDABMV, DLL1
|
| Haploinsufficiency of the Notch Ligand DLL1 Causes Variable Neurodevelopmental Disorders.
|
| Fischer-Zirnsak B, Segebrecht L, Schubach M, Charles P, Alderman E, Brown K, Cadieux-Dion M, Cartwright T, Chen Y, Costin C, Fehr S, Fitzgerald KM, Fleming E, Foss K, Ha T, Hildebrand G, Horn D, Liu S, Marco EJ, McDonald M, McWalter K, Race S, Rush ET, Si Y, Saunders C, Slavotinek A, Stockler-Ipsiroglu S, Telegrafi A, Thiffault I, Torti E, Tsai AC, Wang X, Zafar M, Keren B, Kornak U, Boerkoel CF, Mirzaa G, Ehmke N.
|
| Am J Hum Genet 105(3):631-639. doi: 10.1016/j.ajhg.2019.07.002. Epub 2019 Jul 25. 2019
|
| 2 | DLL1, JAG1, NOTCH1
|
| Both Notch1 and its ligands in B cells promote antibody production.
|
| Zhu G, Wang X, Xiao H, Liu X, Fang Y, Zhai B, Xu R, Han G, Chen G, Hou C, Shen B, Li Y, Ma N, Wu H, Liu G, Wang R.
|
| Mol Immunol 91:17-23. doi: 10.1016/j.molimm.2017.08.021. Epub 2017 Aug 31.
2017
|
| 3 | DLL1, JAG1
|
| Disappearance of centroacinar cells in the Notch ligand-deficient pancreas.
|
| Nakano Y, Negishi N, Gocho S, Mine T, Sakurai Y, Yazawa M, Abe K, Yagita H, Habu S, Kageyama R, Kawaguchi Y, Hozumi K.
|
| Genes Cells 20(6):500-11. doi: 10.1111/gtc.12243. Epub 2015 Apr 27.
2015
|
| 4 | DLL1, DLL4, SYNJ2BP
|
| Synaptojanin-2 binding protein stabilizes the Notch ligands DLL1 and DLL4 and inhibits sprouting angiogenesis.
|
| Adam MG, Berger C, Feldner A, Yang WJ, Wüstehube-Lausch J, Herberich SE, Pinder M, Gesierich S, Hammes HP, Augustin HG, Fischer A.
|
| Circ Res 113(11):1206-18. doi: 10.1161/CIRCRESAHA.113.301686. Epub 2013 Sep 11.
2013
|
| 5 | DLL1, HES1, PTF1A
|
| Ptf1a-mediated control of Dll1 reveals an alternative to the lateral inhibition mechanism.
|
| Ahnfelt-Rønne J, Jørgensen MC, Klinck R, Jensen JN, Füchtbauer EM, Deering T, MacDonald RJ, Wright CV, Madsen OD, Serup P.
|
| Development 139(1):33-45. doi: 10.1242/dev.071761. Epub 2011 Nov 17.
2012
|
| 6 | DLL1, DLL4
|
| Dll1- and dll4-mediated notch signaling are required for homeostasis of intestinal stem cells.
|
| Pellegrinet L, Rodilla V, Liu Z, Chen S, Koch U, Espinosa L, Kaestner KH, Kopan R, Lewis J, Radtke F.
|
| Gastroenterology 140(4):1230-1240.e1-7. Epub 2011 Jan 14.
2011
|
| 7 | DLL1, NOTCH1
|
| NOTCH, a new signaling pathway implicated in holoprosencephaly.
|
| Dupé V, Rochard L, Mercier S, Le Pétillon Y, Gicquel I, Bendavid C, Bourrouillou G, Kini U, Thauvin-Robinet C, Bohan TP, Odent S, Dubourg C, David V.
|
| Hum Mol Genet 20(6):1122-31. Epub 2010 Dec 31.
2011
|
| 8 | CTGF, DLL1
|
| The Notch ligand Delta-like 1 integrates inputs from TGFbeta/Activin and Wnt pathways.
|
| Bordonaro M, Tewari S, Atamna W, Lazarova DL.
|
| Exp Cell Res 317(10):1368-81. Epub 2011 Apr 5.
2011
|
| 9 | DLL1
|
| Delta-like 1 expression promotes goblet cell differentiation in Notch-inactivated human colonic epithelial cells.
|
| Akiyama J, Okamoto R, Iwasaki M, Zheng X, Yui S, Tsuchiya K, Nakamura T, Watanabe M.
|
| Biochem Biophys Res Commun 393(4):662-7. Epub 2010 Feb 17.PMID: 20170633 2010
|
| 10 | DLL1, DLL4
|
| Dll1 and Dll4 function sequentially in the retina and pV2 domain of the spinal cord to regulate neurogenesis and create cell diversity.
|
| Rocha SF, Lopes SS, Gossler A, Henrique D.
|
| Dev Biol 328(1):54-65. Epub 2009 Jan 14.
2009
|
| 11 | DLL1, DLL3
|
| The intracellular region of Notch ligands Dll1 and Dll3 regulates their trafficking and signaling activity.
|
| Heuss SF, Ndiaye-Lobry D, Six EM, Israël A, Logeat F.
|
| Proc Natl Acad Sci U S A 105(32):11212-7. Epub 2008 Aug 1.
2008
|
| 12 | DLL1
|
| Premature myogenic differentiation and depletion of progenitor cells cause severe muscle hypotrophy in Delta1 mutants.
|
| Schuster-Gossler K, Cordes R, Gossler A.
|
| Proc Natl Acad Sci U S A 104(2):537-42. Epub 2006 Dec 28. 2007
|
| 13 | DLL1, DLL3
|
| Divergent functions and distinct localization of the Notch ligands DLL1 and DLL3 in vivo.
|
| Geffers I, Serth K, Chapman G, Jaekel R, Schuster-Gossler K, Cordes R, Sparrow DB, Kremmer E, Dunwoodie SL, Klein T, Gossler A.
|
| J Cell Biol 178(3):465-76.
2007
|
| 14 | DLL1
|
| Notch ligand Delta-like 1 is essential for postnatal arteriogenesis.
|
| Limbourg A, Ploom M, Elligsen D, Sörensen I, Ziegelhoeffer T, Gossler A, Drexler H, Limbourg FP.
|
| Circ Res 100(3):363-71. Epub 2007 Jan 18.
2007
|
| 15 | DLL1,NOTCH1
|
| Activation of the Notch pathway in Down syndrome: cross-talk of Notch and APP.
|
| Fischer DF, van Dijk R, Sluijs JA, Nair SM, Racchi M, Levelt CN, van Leeuwen FW, Hol EM.
|
| FASEB J 19(11):1451-8. 2005
|
| 16 | DLL1,JAG2
|
| The Notch ligands DLL1 and JAG2 act synergistically to regulate hair cell development in the mammalian inner ear.
|
| Kiernan AE, Cordes R, Kopan R, Gossler A, Gridley T.
|
| Development 132(19):4353-62. Epub 2005 Sep 1. 2005
|
| 17 | CADASIL, DLL1, Dll3, DLL4, JAG1, JAG2, NOTCH1, NOTCH2, NOTCH3, NOTCH4 , RBPJ, SCDO1
|
| Notch signaling and inherited disease syndromes.
|
| Gridley T.
|
| Hum Mol Genet 12 Spec No 1:R9-13. Review. 2003
|
| 18 | DLL1,JAG2
|
| The Notch ligands, Delta1 and Jagged2, are substrates for presenilin-dependent gamma-secretase cleavage.
|
| Ikeuchi T, Sisodia SS.
|
| J Biol Chem 278(10):7751-4. Epub 2003 Jan 24. 2003
|
| 19 | DLL1
|
| A soluble form of human Delta-like-1 inhibits differentiation of hematopoieticprogenitor cells.
|
| Han W, Ye Q, Moore MA.
|
| Blood 95(5):1616-25. 2000
|
| 20 | DLL1
|
| Human ligands of the Notch receptor.
|
| Gray GE, Mann RS, Mitsiadis E, Henrique D, Carcangiu ML, Banks A, LeimanJ, Ward D, Ish-Horowitz D, Artavanis-Tsakonas S.
|
| Am J Pathol 154(3):785-94. 1999
|