| 1 | DLEC1
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| Evidence of a tumour suppressor function for DLEC1 in human breast cancer.
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| Al Sarakbi W, Reefy S, Jiang WG, Roberts T, Newbold RF, Mokbel K.
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| Anticancer Res 30(4):1079-82.PMID: 20530412 2010
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| 2 | DLEC1
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| DLEC1 is a functional 3p22.3 tumour suppressor silenced by promoter CpG methylation in colon and gastric cancers.
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| Ying J, Poon FF, Yu J, Geng H, Wong AH, Qiu GH, Goh HK, Rha SY, Tian L, Chan AT, Sung JJ, Tao Q.
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| Br J Cancer 100(4):663-9. Epub 2009 Jan 20.PMID: 19156137 2009
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| 3 | BCL2, DLEC1, HOXA1, HOXA10, KL, NR3C1, SEZ6L, SFRP4, SFRP5, SMAD9, TWIST1
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| DNA methylation profiles of gastric carcinoma characterized by quantitative DNA methylation analysis.
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| Kang GH, Lee S, Cho NY, Gandamihardja T, Long TI, Weisenberger DJ, Campan M, Laird PW.
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| Lab Invest 88(2):161-70. Epub 2007 Dec 24.
2008
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| 4 | DLEC1, MLH1
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| DLEC1 and MLH1 promoter methylation are associated with poor prognosis in non-small cell lung carcinoma.
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| Seng TJ, Currey N, Cooper WA, Lee CS, Chan C, Horvath L, Sutherland RL, Kennedy C, McCaughan B, Kohonen-Corish MR.
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| Br J Cancer 99(2):375-82. Epub 2008 Jul 1.PMID: 18594535 2008
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| 5 | DLEC1
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| Epigenetic inactivation of the deleted in lung and esophageal cancer 1 gene in nasopharyngeal carcinoma.
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| Kwong J, Chow LS, Wong AY, Hung WK, Chung GT, To KF, Chan FL, Daigo Y, Nakamura Y, Huang DP, Lo KW.
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| Genes Chromosomes Cancer 46(2):171-80.PMID: 17099870 2007
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| 6 | DLEC1
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| Candidate tumor-suppressor gene DLEC1 is frequently downregulated by promoter hypermethylation and histone hypoacetylation in human epithelial ovarian cancer.
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| Kwong J, Lee JY, Wong KK, Zhou X, Wong DT, Lo KW, Welch WR, Berkowitz RS, Mok SC.
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| Neoplasia 8(4):268-78. 2006
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| 7 | DLEC1
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| Genome-wide scan for linkage in finnish hereditary prostate cancer (HPC) families identifies novel susceptibility loci at 11q14 and 3p25-26.
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| Schleutker J, Baffoe-Bonnie AB, Gillanders E, Kainu T, Jones MP, Freas-Lutz D, Markey C, Gildea D, Riedesel E, Albertus J, Gibbs KD Jr, Matikainen M, Koivisto PA, Tammela T, Bailey-Wilson JE, Trent JM, Kallioniemi OP.
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| Prostate 57(4):280-9. 2003
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| 8 | DLEC1
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| A candidate tumor suppressor gene, H37, from the human lung cancer tumor suppressor locus 3p21.3.
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| Oh JJ, West AR, Fishbein MC, Slamon DJ.
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| Cancer Res 62(11):3207-13. 2002
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| 9 | RASSF1, DLEC1
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| Epigenetic inactivation of RASSF1A in lung and breast cancers and malignant phenotype suppression.
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| Burbee DG, Forgacs E, Zochbauer-Muller S, Shivakumar L, Fong K, Gao B, Randle D, Kondo M, Virmani A, Bader S, Sekido Y, Latif F, Milchgrub S, Toyooka S, Gazdar AF, Lerman MI, Zabarovsky E, White M, Minna JD.
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| J Natl Cancer Inst 93(9):691-9. 2001
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| 10 | SEMA3B, DLEC1
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| Inhibition of lung cancer cell growth and induction of apoptosis after reexpression of 3p21.3 candidate tumor suppressor gene SEMA3B.
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| Tomizawa Y, Sekido Y, Kondo M, Gao B, Yokota J, Roche J, Drabkin H, Lerman MI, Gazdar AF, Minna JD.
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| Proc Natl Acad Sci U S A 98(24):13954-9. 2001
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| 11 | ST3, TSG14B, TSG1A, DLEC1
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| Analysis of genetic alterations in primary nasopharyngeal carcinoma by comparative genomic hybridization.
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| Fang Y, Guan X, Guo Y, Sham J, Deng M, Liang Q, Li H, Zhang H, Zhou H, Trent J.
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| Genes Chromosomes Cancer 30(3):254-60. 2001
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| 12 | ACY1, APEH, DLEC1, FAM107A, MANF
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| Loss of expression of the DRR 1 gene at chromosomal segment 3p21.1 in renal cell carcinoma.
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| Wang L, Darling J, Zhang JS, Liu W, Qian J, Bostwick D, Hartmann L, Jenkins R, Bardenhauer W, Schutte J, Opalka B, Smith DI.
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| Genes Chromosomes Cancer 27(1):1-10 2000
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| 13 | RARB, DLEC1
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| Lack of correlation between expression of retinoic acid receptor-beta and loss of heterozygosity on chromosome band 3p24 in esophageal cancer.
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| Qiu H, Lotan R, Lippman SM, Xu XC.
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| Genes Chromosomes Cancer 28(2):196-202. 2000
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| 14 | VHL, DLEC1
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| Combined LOH/CGH analysis proves the existence of interstitial 3p deletions in renal cell carcinoma.
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| Alimov A, Kost-Alimova M, Liu J, Li C, Bergerheim U, Imreh S, Klein G, Zabarovsky ER.
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| Oncogene 19(11):1392-9. 2000
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| 15 | RASSF1, DLEC1
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| Epigenetic inactivation of a RAS association domain family protein from the lung tumour suppressor locus 3p21.3.
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| Dammann R, Li C, Yoon JH, Chin PL, Bates S, Pfeifer GP.
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| Nat Genet 25(3):315-9. 2000
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| 16 | DLEC1, SCLC, TSG3B, TSG3G
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| High resolution chromosome 3p allelotyping of human lung cancer and preneoplastic/preinvasive bronchial epithelium reveals multiple, discontinuous sites of 3p allele loss and three regions of frequent breakpoints.
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| Wistuba II, Behrens C, Virmani AK, Mele G, Milchgrub S, Girard L, Fondon JW 3rd, Garner HR, McKay B, Latif F, Lerman MI, Lam S, Gazdar AF, Minna JD.
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| Cancer Res 60(7):1949-60. 2000
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| 17 | DLEC1
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| Comparison of chromosome 3p deletions between cervical precancers synchronous with and without invasive cancer.
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| Guo Z, Hu X, Afink G, Ponten F, Wilander E, Ponten J.
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| Int J Cancer 86(4):518-23. 2000
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| 18 | TP53, TSG2B, DLEC1
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| Detection of loss of heterozygosityat microsatellite loci in esophageal squamous-cell carcinoma.
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| Ikeguchi M, et al.
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| Oncology 56(2):164-8. 1999
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| 19 | DLEC1, FHIT
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| Cancer-specific chromosome alterations in the constitutive fragile region FRA3B.
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| Mimori K, et al.
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| Proc Natl Acad Sci U S A 96(13):7456-61. 1999
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| 20 | DLEC1
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| Molecular cloning of a candidate tumor suppressor gene, DLC1, from chromosome 3p21.3.
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| Daigo Y, et al.
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| Cancer Res 59(8):1966-72. 1999
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| 21 | DLEC1
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| Frequent loss of heterozygosity at chromosome 3p14.2-3p21 in human pancreatic islet cell tumours.
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| Nikiforova MN, et al.
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| Clin Endocrinol (Oxf) 51(1):27-33 1999
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| 22 | OGG1, DLEC1
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| Frequent allelic loss at chromosome 3p distinct from genetic alterations of the 8-oxoguanine DNA glycosylase 1 gene in head and neck cancer.
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| Blons H, Radicella JP, Laccourreye O, Brasnu D, Beaune P, Boiteux S, Laurent-Puig P.
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| Mol Carcinog 26(4):254-60. 1999
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| 23 | DLEC1, FHIT
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| An FHIT tumor suppressor gene?
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| Le Beau MM, et al.
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| Genes Chromosomes Cancer 21 : 281-289. 1998
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| 24 | DLEC1
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| Functional evidence for a nasopharyngeal carcinoma tumor suppressor gene that maps at chromosome 3p21.3.
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| Cheng Y, et al.
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| Proc Natl Acad Sci U S A 95 : 3042-3047. 1998
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| 25 | CTNNB1, DLEC1
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| Beta-catenin mutations in human prostate cancer.
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| Voeller HJ, et al.
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| Cancer Res 58 : 2520-2523. 1998
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| 26 | RASSF1, DLEC1
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| Cloning of a breast cancer homozygous deletion junction narrows the region of search for a 3p21.3 tumor suppressor gene.
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| Sekido Y, et al.
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| Oncogene 16 : 3151-3157. 1998
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| 27 | DLEC1
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| Loss of heterozygosity at chromosome 3p correlates with telomerase activity in renal cell carcinoma.
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| Mehle C, et al.
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| Int J Oncol 13 : 289-295. 1998
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| 28 | CTNNB1, DLEC1
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| Beta-catenin mutation in carcinoma of the uterine endometrium.
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| Fukuchi T, Sakamoto M, Tsuda H, Maruyama K, Nozawa S, Hirohashi S.
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| Cancer Res 58 : 3526-3528. 1998
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| 29 | BRMS1, DLEC1, TSG1G
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| Endocrine tumors of the cervix : morphologic assessment, expression of human papillomavirus, and evaluation for loss of heterozygosity on 1p,3p, 11q, and 17p.
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| Mannion C, et al.
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| Cancer 83 : 1391-1400. 1998
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| 30 | DLEC1
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| Molecular alterations to human chromosome 3p loci in neuroendocrine lung tumors.
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| Kovatich A, et al.
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| Cancer 83 : 1109-1117. 1998
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| 31 | FHIT, DLEC1
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| Loss of FHIT expression in gastric carcinoma.
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| Baffa R, Veronese ML, Santoro R, Mandes B, Palazzo JP, Rugge M, Santoro E, Croce CM, Huebner K.
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| Cancer Res 58 : 4708-4714. 1998
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| 32 | TSG3B, DLEC1, TSG3G
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| Chromosomal duplication accompanies allelic loss in non-small cell lung carcinoma.
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| Varella-Garcia M, Gemmill RM, Rabenhorst SH, Lotto A, Drabkin HA, Archer PA, Franklin WA.
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| Cancer Res 58 : 4701-4707. 1998
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| 33 | FHIT, DLEC1
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| Loss of FHIT function in lung cancer and preinvasive bronchial lesions.
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| Sozzi G, et al.
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| Cancer Res 58 : 5032-5037. 1998
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| 34 | DLEC1, FHIT
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| Chromosome 3p14 homozygous deletions and sequence analysis of FRA3B.
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| Boldog F, et al.
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| Hum Mol Genet 6 : 193-203. 1997
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| 35 | DLEC1
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| Deletion of the short arm of chromosome 3 in breast tumors.
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| Pandis N, et al.
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| Genes Chromosomes Cancer 18 : 241-245. 1997
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| 36 | DLEC1
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| Homozygous deletions of human chromosome 3p in lung tumors.
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| Todd S, et al.
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| Cancer Res 57 : 1344-1352. 1997
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| 37 | VHL, TSG3B, DLEC1
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| Involvement of multiple loci on chromosome 3 in renal cell cancer development.
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| van den Berg A, Buys CH.
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| Genes Chromosomes Cancer 19(2):59-76. 1997
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| 38 | FHIT, RCC3, DLEC1, CRCC
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| Identification of novel 'expressed sequence tags' within the FHIT gene locus in human chromosome region 3p14.2.
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| Lux A, Bardenheuer W, Michael D, Brocker F, Julicher K, Vieten L, Michaelis S, Seeber S, Opalka B, Schutte J.
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| Hum Genet 100(1):90-5. 1997
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| 39 | FHIT, DLEC1
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| The FHIT gene, a multiple tumor suppressor gene encompassing the carcinogen sensitive chromosome fragile site, FRA3B.
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| Huebner K, Hadaczek P, Siprashvili Z, Druck T, Croce CM.
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| Biochim Biophys Acta 1332(3):M65-70. 1997
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| 40 | FHIT, DLEC1
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| The putative tumor suppressor gene FHIT at 3p14.2 is rarely affected by loss of heterozygosity in primary human brain tumors.
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| Frank S, Muller J, Plaschke J, Hahn M, Hampl J, Hampl M, Pistorius S, Schackert G, Schackert HK.
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| Cancer Res 57(13):2638-41. 1997
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| 41 | DLEC1, FHIT
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| Precise localization of the FHIT gene to the common fragile site at 3p14.2 (FRA3B) and characterization of homozygous deletions within FRA3B that affect FHIT transcription in tumor cell lines.
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| Ong ST, Fong KM, Bader SA, Minna JD, Le Beau MM, McKeithan TW, Rassool FV.
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| Genes Chromosomes Cancer 20(1):16-23. 1997
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| 42 | DLEC1
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| Detailed deletion mapping of chromosome arm 3p in breast cancers : A 2-cM region on 3p14.3-21.1 and a 5-cM region on 3p24.3-25.1 commonly deleted in tumors.
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| Matsumoto S, Kasumi F, Sakamoto G, Onda M, Nakamura Y, Emi M.
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| Genes Chromosomes Cancer 20(3):268-74. 1997
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| 43 | TSG3B, DLEC1
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| Deletion mapping of the short arm of chromosome 3 in Merkel cell carcinoma.
|
| Leonard JH, et al.
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| Genes Chromosomes Cancer 15 : 102-107. 1996
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| 44 | TSG3B, DLEC1
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| Frequent allelic loss at chromosome arm 3p is distinct from genetic alterations of the Von-Hippel Lindau tumor suppressor gene in head and neck cancer.
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| Waber PG, et al.
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| Oncogene 12 : 365-369. 1996
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| 45 | DLEC1
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| Potential gastrointestinal tumor suppressor locus at the 3p14.2 FRA3B site identified by homozygous deletions in tumor cell lines.
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| Kastury K, et al.
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| Cancer Res 56 : 978-983. 1996
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| 46 | DLEC1, D3S@, PTPRG
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| Construction of a consistent YAC contig for human chromosome region 3p14.1.
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| Bardenheuer W, et al.
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| Genome Res 6 : 176-186. 1996
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| 47 | FHIT, DLEC1
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| The FHIT gene at 3p14.2 is abnormal in breast carcinomas.
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| Negrini M, et al.
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| Cancer Res 56 : 3173-3179. 1996
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| 48 | DLEC1
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| Loss of heterozygosity on chromosome arm 3p in nasopharyngeal carcinoma.
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| Hu LF, et al.
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| Genes Chromosomes Cancer 17 : 118-126. 1996
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| 49 | ATM, FHIT, DLEC1, ST3
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| High levels of allele loss at the FHIT and ATM genes in non-comedo ductal carcinoma in situ and grade I tubular invasive breast cancers.
|
| Man S, et al.
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| Cancer Res 56 : 5484-5489. 1996
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| 50 | TSG3B, DLEC1
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| Distinct patterns of chromosomal alterations in high- and low-grade head and neck squamous cell carcinomas.
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| BockmŸhl U, et al.
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| Cancer Res 56 : 5325-5329. 1996
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| 51 | DLEC1
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| Refining a proximal breakpoint cluster at chromosome 3p11.2 in non-papillary renal cell carcinomas.
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| Bugert P, et al.
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| Int J Cancer 68 : 723-726. 1996
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| 52 | RCC3, TSG3B, DLEC1, PTPRG
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| Loss of heterozygosity at the familial RCC t(3;8) locus in most clear cell renal carcinomas.
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| Druck T, et al.
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| Cancer Res 55 : 5348-5353. 1995
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| 53 | DLEC1, FHIT
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| Precise localization of aphidicolin-induced breakpoints on the short arm of human chromosome 3.
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| Paradee W, et al.
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| Genomics 27 : 358-361. 1995
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| 54 | VHL, TSG3B, DLEC1
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| Molecular genetic investigation of sporadic renal cell carcinoma : analysis of allele loss on chromosomes 3p, 5q, 11p, 17 and 22.
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| Foster K, Crossey PA, Cairns P, Hetherington JW, Richards FM, Jones MH, Bentley E, Affara NA, Ferguson-Smith MA, Maher ER.
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| Br J Cancer 69 : 230-234. 1994
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| 55 | DLEC1
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| Common regions of deletion in chromosome regions 3p12 and 3p14.2 in primary clear cell renal carcinomas.
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| Lubinski J, et al.
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| Cancer Res 54 : 3710-3713. 1994
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| 56 | TSG3B, DLEC1
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| Deletion of two separate regions on chromosome 3p in breast cancer.
|
| Chen LC, et al.
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| Cancer Res 54 : 3021-3024. 1994
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| 57 | VHL, TSG3B, DLEC1
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| Transfer of human chromosome 3 to an ovarian carcinoma cell line identifies three regions on 3p involved in ovarian cancer.
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| Rimessi P, Gualandi F, Morelli C, Trabanelli C, Wu Q, Possati L, Montesi M, Barrett JC, Barbanti-Brodano G.
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| Oncogene 9 : 3467-3474. 1994
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| 58 | TSG1F, DLEC1, TSG4D, TSG5C
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| Allelotype analysis of cervical carcinoma.
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| Mitra AB, et al.
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| Cancer Res 54 : 4481-4487. 1994
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| 59 | RCC3, DLEC1, NRC1
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| A tumor suppressor locus within 3p14-p12 mediates rapid cell death of renal cell carcinoma in vivo.
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| Sanchez Y, el-Naggar A, Pathak S, Killary AM.
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| Proc Natl Acad Sci U S A 91(8):3383-7. 1994
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| 60 | DLEC1
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| Interstitial deletion of the short arm of chromosome 3 as a primary chromosome abnormality in carcinomas of the breast.
|
| Pandis N, et al.
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| Genes Chromosomes Cancer 6 : 151-155. 1993
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| 61 | TSG3B, DLEC1
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| Three discrete regions of deletion at 3p in head and neck cancers.
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| Maestro R, et al.
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| Cancer Res 53 : 5775-5779. 1993
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| 62 | RCC3, DLEC1
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| Detailed genetic and physical map of the 3p chromosome region surrounding the familial renal cell carcinoma chromosome translocation, t(3;8)(p14.2;q24.1).
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| LaForgia S, et al.
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| Cancer Res 53 : 3118-3124. 1993
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| 63 | RCC3, DLEC1
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| Positional cloning of the hereditary renal carcinoma 3;8 chromosome translocation breakpoint.
|
| Boldog FL, et al.
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| Proc Natl Acad Sci U S A 90 : 8509-8513. 1993
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| 64 | VHL, TSG3B, DLEC1
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| Three distinct regions involved in 3p deletion in human lung cancer.
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| Hibi K, Takahashi T, Yamakawa K, Ueda R, Sekido Y, Ariyoshi Y, Suyama M, Takagi H, Nakamura Y, Takahashi T.
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| Oncogene 7 : 445-449. 1992
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| 65 | DLEC1
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| Molecular characterization of a large homozygous deletion in the small cell lung cancer cell line U2020 : a strategy for cloning the putative tumor suppressor gene.
|
| Latif F, et al.
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| Genes Chromosomes Cancer 5 : 119-127. 1992
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| 66 | RCC3, DLEC1
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| Cytogenetic and molecular studies of a familial renal cell carcinoma.
|
| Decker HJH, et al.
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| Cancer Genet Cytogenet 63 : 25-31. 1992
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| 67 | RCC3, DLEC1, CRCC
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| Involvement of 3p deletions in sporadic and hereditary forms of renal cell carcinoma.
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| Boldog F, et al.
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| Genes Chromosomes Cancer 3 : 403-406. 1991
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| 68 | VHL, TSG3B, DLEC1
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| Histopathological, cytogenetic, and molecular characterization of renal cortical tumors.
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| Presti JC Jr, Rao PH, Chen Q, Reuter VE, Li FP, Fair WR, Jhanwar SC.
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| Cancer Res 51 : 1544-1552. 1991
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| 69 | TSG3B, DLEC1
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| A detailed deletion mapping of the short arm of chromosome 3 in sporadic renal cell carcinoma.
|
| Yamakawa K, et al.
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| Cancer Res 51 : 4707-4711. 1991
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| 70 | DLEC1
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| An usually proximal deletion on the short arm of chromosome 3 in a patient with small cell lung cancer.
|
| Daly MC, et al.
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| Genomics 9 : 113-119. 1991
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| 71 | TSG3B, DLEC1
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| Frequency and extent of allelic loss in the short arm of chromosome 3 in non small-cell lung cancer.
|
| Rabbitts P, et al.
|
| Genes Chromosomes Cancer 1 : 95-105. 1989
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| 72 | CRCC, DLEC1
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| Loss of der(3) in renal carcinoma cells of a patient with constitutional t(3;12).
|
| Kovacs G, et al.
|
| Hum Genet 78 : 148-150. 1988
|
| 73 | CRCC, DLEC1
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| Consistent chromosome 3p deletion and loss of heterozygosity in renal cell carcinoma.
|
| Kovacs G, et al.
|
| Proc Natl Acad Sci U S A 85 : 1571-1575. 1988
|
| 74 | TSG3B, DLEC1, TSG13A, TSG17A
|
| Loss of heterozygosity on chromosomes 3, 13, and 17 in small-cell carcinoma and on chromosome 3 in adenocarcinoma of the lung.
|
| Yokota J, et al.
|
| Proc Natl Acad Sci U S A 84 : 9252-9256. 1987
|