| 1 | DKK3, XDH
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| Dickkopf 3 attenuates xanthine dehydrogenase expression to prevent oxidative stress-induced apoptosis.
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| Qui S, Kano J, Noguchi M.
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| Genes Cells 22(4):406-417. doi: 10.1111/gtc.12484. Epub 2017 Mar 15.
2017
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| 2 | DKK3
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| Dickkopf-3 Ablation Attenuates the Development of Atherosclerosis in ApoE-Deficient Mice.
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| Cheng WL, Yang Y, Zhang XJ, Guo J, Gong J, Gong FH, She ZG, Huang Z, Xia H, Li H.
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| J Am Heart Assoc 6(2). pii: e004690. doi: 10.1161/JAHA.116.004690.
2017
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| 3 | DKK3
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| Expression pattern of DKK3, dickkopf WNT signaling pathway inhibitor 3, in the malignant progression of oral submucous fibrosis.
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| Zhou S, Zhu Y, Mashrah M, Zhang X, He Z, Yao Z, Zhang C, Guo F, Hu Y, Zhang C.
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| Oncol Rep 37(2):979-985. doi: 10.3892/or.2016.5307. Epub 2016 Dec 8.
2017
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| 4 | DKK3
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| Dkk3 prevents familial dilated cardiomyopathy development through Wnt pathway.
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| Lu D, Bao D, Dong W, Liu N, Zhang X, Gao S, Ge W, Gao X, Zhang L.
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| Lab Invest 96(2):239-48. doi: 10.1038/labinvest.2015.145. Epub 2015 Dec 7.
2016
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| 5 | DKK3, SGTA
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| Tumor suppressor REIC/DKK-3 and co-chaperone SGTA: Their interaction and roles in the androgen sensitivity.
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| Ochiai K, Morimatsu M, Kato Y, Ishiguro-Oonuma T, Udagawa C, Rungsuriyawiboon O, Azakami D, Michishita M, Ariyoshi Y, Ueki H, Nasu Y, Kumon H, Watanabe M, Omi T.
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| Oncotarget 7(3):3283-96. doi: 10.18632/oncotarget.6488.
2016
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| 6 | DKK3
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| Dickkopf Homolog 3 Induces Stem Cell Differentiation into Smooth Muscle Lineage via ATF6 Signalling.
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| Wang X, Karamariti E, Simpson R, Wang W, Xu Q.
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| J Biol Chem 290(32):19844-52. doi: 10.1074/jbc.M115.641415. Epub 2015 Jun 23.
2015
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| 7 | DKK3
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| The cysteine-rich core domain of REIC/Dkk-3 is critical for its effect on monocyte differentiation and tumor regression.
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| Kinoshita R, Watanabe M, Huang P, Li SA, Sakaguchi M, Kumon H, Futami J.
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| Oncol Rep 33(6):2908-14. doi: 10.3892/or.2015.3885. Epub 2015 Mar 30.
2015
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| 8 | DKK3
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| Dickkopf-3 acts as a modulator of B cell fate and function.
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| Ludwig J, Federico G, Prokosch S, Küblbeck G, Schmitt S, Klevenz A, Gröne HJ, Nitschke L, Arnold B.
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| J Immunol 194(6):2624-34. doi: 10.4049/jimmunol.1402160. Epub 2015 Feb 11.
2015
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| 9 | DKK3, PPM1D
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| Phosphatase WIP1 regulates adult neurogenesis and WNT signaling during aging.
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| Zhu Y, Demidov ON, Goh AM, Virshup DM, Lane DP, Bulavin DV.
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| J Clin Invest 124(7):3263-73. doi: 10.1172/JCI73015. Epub 2014 Jun 9.
2014
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| 10 | DKK3
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| Dickkopf-3 attenuates pressure overload-induced cardiac remodelling.
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| Zhang Y, Liu Y, Zhu XH, Zhang XD, Jiang DS, Bian ZY, Zhang XF, Chen K, Wei X, Gao L, Zhu LH, Yang Q, Fan GC, Lau WB, Ma X, Li H.
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| Cardiovasc Res 102(1):35-45. doi: 10.1093/cvr/cvu004. Epub 2014 Jan 9.
2014
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| 11 | DKK1, DKK2, DKK3, DKK4
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| The effects of Dickkopf-4 on the proliferation, differentiation, and apoptosis of osteoblasts.
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| Hiramitsu S, Terauchi M, Kubota T.
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| Endocrinology 154(12):4618-26. doi: 10.1210/en.2013-1387.
2013
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| 12 | DKK3
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| Dickkopf homolog 3 (DKK3) plays a crucial role upstream of WNT/β-CATENIN signaling for Sertoli cell mediated regulation of spermatogenesis.
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| Das DS, Wadhwa N, Kunj N, Sarda K, Pradhan BS, Majumdar SS.
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| PLoS One 8(5):e63603. doi: 10.1371/journal.pone.0063603. Print 2013.
2013
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| 13 | DKK3
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| Dickkopf-3, an immune modulator in peripheral CD8 T-cell tolerance.
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| Papatriantafyllou M, Moldenhauer G, Ludwig J, Tafuri A, Garbi N, Hollmann G, Küblbeck G, Klevenz A, Schmitt S, Pougialis G, Niehrs C, Gröne HJ, Hämmerling GJ, Arnold B, Oelert T.
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| Proc Natl Acad Sci U S A 109(5):1631-6. doi: 10.1073/pnas.1115980109. Epub 2012 Jan 17.
2012
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| 14 | DKK3
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| Dkk3 is a component of the genetic circuitry regulating aldosterone biosynthesis in the adrenal cortex.
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| El Wakil A, Bandulik S, Guy N, Bendahhou S, Zennaro MC, Niehrs C, Mari B, Warth R, Barhanin J, Lalli E.
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| Hum Mol Genet 21(22):4922-9. doi: 10.1093/hmg/dds333. Epub 2012 Aug 23.
2012
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| 15 | DKK3, DYNLT1
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| Tumor suppressor REIC/Dkk-3 interacts with the dynein light chain, Tctex-1.
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| Ochiai K, Watanabe M, Ueki H, Huang P, Fujii Y, Nasu Y, Noguchi H, Hirata T, Sakaguchi M, Huh NH, Kashiwakura Y, Kaku H, Kumon H.
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| Biochem Biophys Res Commun 412(2):391-5. Epub 2011 Aug 3.
2011
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| 16 | DKK3
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| Expression of REIC/Dkk-3 in normal and hyperproliferative epidermis.
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| Du G, Kataoka K, Sakaguchi M, Abarzua F, Than SS, Sonegawa H, Makino T, Shimizu T, Huh NH.
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| Exp Dermatol 20(3):273-7. doi: 10.1111/j.1600-0625.2010.01244.x.
2011
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| 17 | DKK3
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| Internalization of REIC/Dkk-3 protein by induced pluripotent stem cell-derived embryoid bodies and extra-embryonic tissues.
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| Kataoka K, Sakaguchi M, Li KP, Taketa C, Yamamoto K, Du G, Funahashi H, Murata H, Huh NH.
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| Int J Mol Med 26(6):853-9.
2010
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| 18 | CTNNB1, DKK3
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| Dkk3, downregulated in cervical cancer, functions as a negative regulator of beta-catenin.
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| Lee EJ, Jo M, Rho SB, Park K, Yoo YN, Park J, Chae M, Zhang W, Lee JH.
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| Int J Cancer 124(2):287-97.
2009
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| 19 | DKK3
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| Prognostic relevance of Wnt-inhibitory factor-1 (WIF1) and Dickkopf-3 (DKK3) promoter methylation in human breast cancer.
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| Veeck J, Wild PJ, Fuchs T, Schüffler PJ, Hartmann A, Knüchel R, Dahl E.
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| BMC Cancer 9:217.PMID: 19570204 2009
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| 20 | DKK3
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| Overexpression of Dickkopf 3 in hepatoblastomas and hepatocellular carcinomas.
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| Pei Y, Kano J, Iijima T, Morishita Y, Inadome Y, Noguchi M.
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| Virchows Arch 454(6):639-46. Epub 2009 May 13.PMID: 19437037 2009
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| 21 | DKK3
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| An N-terminal 78 amino acid truncation of REIC/Dkk-3 effectively induces apoptosis.
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| Abarzua F, Kashiwakura Y, Takaoka M, Watanabe M, Ochiai K, Sakaguchi M, Iwawaki T, Tanimoto R, Nasu Y, Huh NH, Kumon H.
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| Biochem Biophys Res Commun 375(4):614-8. Epub 2008 Aug 24.
2008
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| 22 | DKK3, MYCN
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| Dickkopf-3 expression is a marker for neuroblastic tumor maturation and is down-regulated by MYCN.
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| Koppen A, Ait-Aissa R, Koster J, Øra I, Bras J, van Sluis PG, Caron H, Versteeg R, Valentijn LJ.
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| Int J Cancer 122(7):1455-64.PMID: 18059033 2008
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| 23 | DKK3
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| REIC/Dkk-3 as a potential gene therapeutic agent against human testicular cancer.
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| Tanimoto R, Abarzua F, Sakaguchi M, Takaishi M, Nasu Y, Kumon H, Huh NH.
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| Int J Mol Med 19(3):363-8.
2007
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| 24 | DKK3
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| Dickkopf-3 is expressed in a subset of adult human pancreatic beta cells.
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| Hermann M, Pirkebner D, Draxl A, Berger P, Untergasser G, Margreiter R, Hengster P.
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| Histochem Cell Biol 127(5):513-21. Epub 2007 Mar 9.
2007
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| 25 | DKK3
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| Expression of Dickkopf genes is strongly reduced in malignant melanoma.
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| Kuphal S, Lodermeyer S, Bataille F, Schuierer M, Hoang BH, Bosserhoff AK.
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| Oncogene 25(36):5027-36. Epub 2006 Mar 27. 2006
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| 26 | DKK3
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| Regulation of prostate cell growth and morphogenesis by Dickkopf-3.
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| Kawano Y, Kitaoka M, Hamada Y, Walker MM, Waxman J, Kypta RM.
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| Oncogene 25(49):6528-37. Epub 2006 Jun 5.
2006
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| 27 | DKK3
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| Dickkopf-3/REIC functions as a suppressor gene of tumor growth.
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| Hsieh SY, Hsieh PS, Chiu CT, Chen WY.
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| Oncogene 23(57):9183-9. 2004
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| 28 | DKK3
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| Reduced expression of the REIC/Dkk-3 gene by promoter-hypermethylation in human tumor cells.
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| Kobayashi K, Ouchida M, Tsuji T, Hanafusa H, Miyazaki M, Namba M, Shimizu N, Shimizu K.
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| Gene 282(1-2):151-8. 2002
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| 29 | DKK1, DKK2, DKK3, LRP6
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| LDL-receptor-related protein 6 is a receptor for Dickkopf proteins.
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| Mao B, Wu W, Li Y, Hoppe D, Stannek P, Glinka A, Niehrs C.
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| Nature 411(6835):321-5. 2001
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| 30 | DKK3
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| Reduced expression of REIC/Dkk-3 gene in non-small cell lung cancer.
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| Nozaki I, Tsuji T, Iijima O, Ohmura Y, Andou A, Miyazaki M, Shimizu N, Namba M.
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| Int J Oncol 19(1):117-21. 2001
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| 31 | DKK3
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| A REIC gene shows down-regulation in human immortalized cells and human tumor-derived cell lines.
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| Tsuji T, Miyazaki M, Sakaguchi M, Inoue Y, Namba M.
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| Biochem Biophys Res Commun 268(1):20-4. 2000
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| 32 | DKK1, DKK2, DKK3, DKK4, DKKL1
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| Functional and structural diversity of the human Dickkopf gene family.
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| Krupnik VE, Sharp JD, Jiang C, Robison K, Chickering TW, Amaravadi L, Brown DE, Guyot D, Mays G, Leiby K, Chang B, Duong T, Goodearl AD, Gearing DP, Sokol SY, McCarthy SA.
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| Gene 238(2):301-13. 1999
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| 33 | DKK1, DKK2, DKK3
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| Dickkopf genes are co-ordinately expressed in mesodermal lineages.
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| Monaghan AP, Kioschis P, Wu W, Zuniga A, Bock D, Poustka A, Delius H, Niehrs C.
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| Mech Dev 87(1-2):45-56. 1999
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