Citations for
1DKK2
Association study of DKK2 polymorphisms with alcohol dependence and alcohol-related harm.
Kim JY, Bae JS, Park BL, Kim JH, Kim LH, Kim JW, Lee BC, Kang TC, Choi IG, Shin HD.
Alcohol Clin Exp Res 38(2):545-50. doi: 10.1111/acer.12265. Epub 2013 Oct 7. 2014
2DKK1, DKK2
Distinct roles of DKK1 and DKK2 in tumor angiogenesis.
Park H, Jung HY, Choi HJ, Kim DY, Yoo JY, Yun CO, Min JK, Kim YM, Kwon YG.
Angiogenesis 17(1):221-34. doi: 10.1007/s10456-013-9390-5. Epub 2013 Oct 4. 2014
3DKK2
DKK2 mediates osteolysis, invasiveness, and metastatic spread in Ewing sarcoma.
Hauer K, Calzada-Wack J, Steiger K, Grunewald TG, Baumhoer D, Plehm S, Buch T, Prazeres da Costa O, Esposito I, Burdach S, Richter GH.
Cancer Res 73(2):967-77. doi: 10.1158/0008-5472.CAN-12-1492. Epub 2012 Nov 30. 2013
4BMP4, DKK2, MSX1, OSR2
Roles of Bmp4 during tooth morphogenesis and sequential tooth formation.
Jia S, Zhou J, Gao Y, Baek JA, Martin JF, Lan Y, Jiang R.
Development 140(2):423-32. doi: 10.1242/dev.081927. 2013
5DKK1, DKK2, DKK3, DKK4
The effects of Dickkopf-4 on the proliferation, differentiation, and apoptosis of osteoblasts.
Hiramitsu S, Terauchi M, Kubota T.
Endocrinology 154(12):4618-26. doi: 10.1210/en.2013-1387. 2013
6DKK2
Chemical and genetic evidence for the involvement of Wnt antagonist Dickkopf2 in regulation of glucose metabolism.
Li X, Shan J, Chang W, Kim I, Bao J, Lee HJ, Zhang X, Samuel VT, Shulman GI, Liu D, Zheng JJ, Wu D.
Proc Natl Acad Sci U S A 109(28):11402-7. doi: 10.1073/pnas.1205015109. Epub 2012 Jun 25. Erratum in: Proc Natl Acad Sci U S A. 2012 Oct 16;109(42):17141 2012
7DKK1, DKK2
The WNT antagonist Dickkopf2 promotes angiogenesis in rodent and human endothelial cells.
Min JK, Park H, Choi HJ, Kim Y, Pyun BJ, Agrawal V, Song BW, Jeon J, Maeng YS, Rho SS, Shim S, Chai JH, Koo BK, Hong HJ, Yun CO, Choi C, Kim YM, Hwang KC, Kwon YG.
J Clin Invest 121(5):1882-93. doi: 10.1172/JCI42556. Epub 2011 Apr 11. 2011
8DKK1, DKK2
Dkk1 and Dkk2 regulate epicardial specification during mouse heart development.
Phillips MD, Mukhopadhyay M, Poscablo C, Westphal H.
Int J Cardiol 150(2):186-92. doi: 10.1016/j.ijcard.2010.04.007. Epub 2010 May 2. 2011
9DKK1, DKK2
Dkk1 and Dkk2 regulate epicardial specification during mouse heart development.
Phillips MD, Mukhopadhyay M, Poscablo C, Westphal H.
Int J Cardiol nt J Cardiol. 2010 May 2. [Epub ahead of print]PMID: 20439124 2010
10DKK2
A systematic gene-based screen of chr4q22-q32 identifies association of a novel susceptibility gene, DKK2, with the quantitative trait of alcohol dependence symptom counts.
Kalsi G, Kuo PH, Aliev F, Alexander J, McMichael O, Patterson DG, Walsh D, Zhao Z, Schuckit M, Nurnberger J Jr, Edenberg H, Kramer J, Vladimirov V, Prescott CA, Dick DM, Kendler KS, Riley BP.
Hum Mol Genet 19(12):2497-506. Epub 2010 Mar 23.PMID: 20332099 2010
11DKK2
Wnt antagonist gene DKK2 is epigenetically silenced and inhibits renal cancer progression through apoptotic and cell cycle pathways.
Hirata H, Hinoda Y, Nakajima K, Kawamoto K, Kikuno N, Kawakami K, Yamamura S, Ueno K, Majid S, Saini S, Ishii N, Dahiya R.
Clin Cancer Res 15(18):5678-87.PMID: 19755393 2009
12DKK2
Expression and regulation of Dickkopf2 during periimplantation in mice.
Zhang Y, Peng S, Kuang H, Chen Q, Liu S, Zhang L, Duan E.
J Reprod Dev 55(1):17-22. Epub 2008 Aug 8.PMID: 18689976 2009
13DKK2, DKK4
DICKKOPF-4 and -2 genes are upregulated in human colorectal cancer.
Matsui A, Yamaguchi T, Maekawa S, Miyazaki C, Takano S, Uetake T, Inoue T, Otaka M, Otsuka H, Sato T, Yamashita A, Takahashi Y, Enomoto N.
Cancer Sci 100(10):1923-30. doi: 10.1111/j.1349-7006.2009.01272.x. 2009
14DKK2
Structural insight into the mechanisms of Wnt signaling antagonism by Dkk.
Chen L, Wang K, Shao Y, Huang J, Li X, Shan J, Wu D, Zheng JJ.
J Biol Chem 283(34):23364-70. Epub 2008 Jun 3.PMID: 18524778 2008
15DKK2
The canonical Wnt signaling antagonist DKK2 is an essential effector of PITX2 function during normal eye development.
Gage PJ, Qian M, Wu D, Rosenberg KI.
Dev Biol 317(1):310-24. Epub 2008 Mar 4.PMID: 18367164 2008
16DKK2
WNT antagonist, DKK2, is a Notch signaling target in intestinal stem cells: augmentation of a negative regulation system for canonical WNT signaling pathway by the Notch-DKK2 signaling loop in primates.
Katoh M, Katoh M.
Int J Mol Med 19(1):197-201.PMID: 17143565 2007
17DKK2
Dkk2 plays an essential role in the corneal fate of the ocular surface epithelium.
Mukhopadhyay M, Gorivodsky M, Shtrom S, Grinberg A, Niehrs C, Morasso MI, Westphal H.
Development 133(11):2149-54. Epub 2006 May 3. Erratum in: Development. 2006 Jun;133(12):2447. Development. 2006 Jul;133(13):2595. PMID: 1667 2006
18DKK2, WNT7B
Dkk2 has a role in terminal osteoblast differentiation and mineralized matrix formation.
Li X, Liu P, Liu W, Maye P, Zhang J, Zhang Y, Hurley M, Guo C, Boskey A, Sun L, Harris SE, Rowe DW, Ke HZ, Wu D.
Nat Genet 37(9):945-52. Epub 2005 Jul 31. 2005
19DKK2, LRP6
Second cysteine-rich domain of Dickkopf-2 activates canonical Wnt signaling pathway via LRP-6 independently of dishevelled.
Li L, Mao J, Sun L, Liu W, Wu D.
J Biol Chem 277(8):5977-81. 2002
20DKK1, DKK2, DKK3, LRP6
LDL-receptor-related protein 6 is a receptor for Dickkopf proteins.
Mao B, Wu W, Li Y, Hoppe D, Stannek P, Glinka A, Niehrs C.
Nature 411(6835):321-5. 2001
21DKK1, DKK2, DKK3, DKK4, DKKL1
Functional and structural diversity of the human Dickkopf gene family.
Krupnik VE, Sharp JD, Jiang C, Robison K, Chickering TW, Amaravadi L, Brown DE, Guyot D, Mays G, Leiby K, Chang B, Duong T, Goodearl AD, Gearing DP, Sokol SY, McCarthy SA.
Gene 238(2):301-13. 1999
22DKK1, DKK2, DKK3
Dickkopf genes are co-ordinately expressed in mesodermal lineages.
Monaghan AP, Kioschis P, Wu W, Zuniga A, Bock D, Poustka A, Delius H, Niehrs C.
Mech Dev 87(1-2):45-56. 1999