| 1 | DHX9
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| Nucleic DHX9 cooperates with STAT1 to transcribe interferon-stimulated genes.
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| Ren X, Wang D, Zhang G, Zhou T, Wei Z, Yang Y, Zheng Y, Lei X, Tao W, Wang A, Li M, Flavell RA, Zhu S.
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| Sci Adv. Feb 3;9(5):eadd5005. doi: 10.1126/sciadv.add5005. Epub 2023 Feb 3. 2023
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| 2 | CMT2EE, DHX9, DIMBE
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| Monoallelic variation in DHX9, the gene encoding the DExH-box helicase DHX9, underlies neurodevelopment disorders and Charcot-Marie-Tooth disease. 2023 PMID:
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| Calame DG, Guo T, Wang C, Garrett L, Jolly A, Dawood M, Kurolap A, Henig NZ, Fatih JM, Herman I, Du H, Mitani T, Becker L, Rathkolb B, Gerlini R, Seisenberger C, Marschall S, Hunter JV, Gerard A, Heidlebaugh A, Challman T, Spillmann RC, Jhangiani SN, Coban-Akdemir Z, Lalani S, Liu L, Revah-Politi A, Iglesias A, Guzman E, Baugh E, Boddaert N, Rondeau S, Ormieres C, Barcia G, Tan QKG, Thiffault I, Pastinen T, Sheikh K, Biliciler S, Mei D, Melani F, Shashi V, Yaron Y, Steele M, Wakeling E, Østergaard E, Nazaryan-Petersen L; Undiagnosed Diseases Network; Millan F, Santiago-Sim T, Thevenon J, Bruel AL, Thauvin-Robinet C, Popp D, Platzer K, Gawlinski P, Wiszniewski W, Marafi D, Pehlivan D, Posey JE, Gibbs RA, Gailus-Durner V, Guerrini R, Fuchs H, Hrabě de Angelis M, Hölter SM, Cheung HH, Gu S, Lupski JR.
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| Am J Hum Genet. Aug 3;110(8):1394-1413. doi: 10.1016/j.ajhg.2023.06.013. Epub 2023 Jul 18. 2023
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| 3 | DHX9, DIMBE
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| Heterozygous loss-of-function DHX9 variants are associated with neurodevelopmental disorders: Human genetic and experimental evidences.
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| Yamada M, Nitta Y, Uehara T, Suzuki H, Miya F, Takenouchi T, Tamura M, Ayabe S, Yoshiki A, Maeno A, Saga Y, Furuse T, Yamada I, Okamoto N, Kosaki K, Sugie A.
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| Eur J Med Genet. Aug;66(8):104804. doi: 10.1016/j.ejmg.2023.104804. Epub 2023 Jun 25. 2023
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| 4 | DHX9
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| The enigmatic helicase DHX9 as a candidate prognostic biomarker for resected pancreatic ductal adenocarcinoma.
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| Chen LG, Cui Y, Lu WQ, Wu H, Jiang JS, Ding KF.
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| Front Oncol. Dec 12;12:1066717. doi: 10.3389/fonc.2022.1066717. 2022
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| 5 | DHX9
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| DHX9-dependent recruitment of BRCA1 to RNA promotes DNA end resection in homologous recombination
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| Chakraborty P, Hiom K.
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| Nat Commun. Jul 5;12(1):4126. doi: 10.1038/s41467-021-24341-z. 2021
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| 6 | CIZ1, DHX9
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| Identification of DHX9 as a cell cycle regulated nucleolar recruitment factor for CIZ1
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| Thacker U, Pauzaite T, Tollitt J, Twardowska M, Harrison C, Dowle A, Coverley D, Copeland NA.
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| Sci Rep. Oct 22;10(1):18103. doi: 10.1038/s41598-020-75160-z. 2020
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| 7 | DHX9
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| DHX9 helicase promotes R-loop formation in cells with impaired RNA splicing.
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| Chakraborty P, Huang JTJ, Hiom K.
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| Nat Commun. Oct 19;9(1):4346. doi: 10.1038/s41467-018-06677-1. 2018
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| 8 | DHX9
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| Dependence of p53-deficient cells on the DHX9 DExH-box helicase.
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| Lee T, Pelletier J.
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| Oncotarget. May 9;8(19):30908-30921. doi: 10.18632/oncotarget.15889. 2017
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| 9 | DHX9
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| The biology of DHX9 and its potential as a therapeutic target.
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| Lee T, Pelletier J.
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| Oncotarget. Jul 5;7(27):42716-42739. doi: 10.18632/oncotarget.8446 2016
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| 10 | DHX9
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| Tumor cell survival dependence on the DHX9 DExH-box helicase.
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| Lee T, Paquet M, Larsson O, Pelletier J.
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| Oncogene. Sep 29;35(39):5093-105. doi: 10.1038/onc.2016.52. Epub 2016 Mar 14. 2016
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| 11 | DDX1, DHX3X, DHX9
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| DExD/H-box RNA helicases as mediators of anti-viral innate immunity and essential host factors for viral replication.
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| Fullam A, Schröder M.
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| Biochim Biophys Acta 1829(8):854-65. doi: 10.1016/j.bbagrm.2013.03.012. Epub 2013 Apr 6. Review.
2013
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| 12 | DHX9
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| DHX9 helicase is involved in preventing genomic instability induced by alternatively structured DNA in human cells.
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| Jain A, Bacolla A, Del Mundo IM, Zhao J, Wang G, Vasquez KM.
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| Nucleic Acids Res. Dec;41(22):10345-57. doi: 10.1093/nar/gkt804. Epub 2013 Sep 17 2013
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| 13 | DHX9, WRN
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| WRN helicase unwinds Okazaki fragment-like hybrids in a reaction stimulated by the human DHX9 helicase.
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| Chakraborty P, Grosse F.
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| Nucleic Acids Res 38(14):4722-30. Epub 2010 Apr 12.
2010
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| 14 | DHX9
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| Human DHX9 helicase unwinds triple-helical DNA structures.
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| Jain A, Bacolla A, Chakraborty P, Grosse F, Vasquez KM.
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| Biochemistry 49(33):6992-9.
2010
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| 15 | DHX9
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| RNA helicase A acts as a bridging factor linking nuclear beta-actin with RNA polymerase II.
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| Tang W, You W, Shi F, Qi T, Wang L, Djouder Z, Liu W, Zeng X.
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| Biochem J 420(3):421-8.PMID: 19309309 2009
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| 16 | DHX9, EIF2AK2
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| An antiviral response directed by PKR phosphorylation of the RNA helicase A.
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| Sadler AJ, Latchoumanin O, Hawkes D, Mak J, Williams BR.
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| PLoS Pathog 5(2):e1000311. Epub 2009 Feb 20.PMID: 19229320 2009
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| 17 | DHX9
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| Guanine nucleotide depletion mediates translocation of nucleolar proteins, including RNA helicase A (DHX-9).
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| Huang M, Mitchell BS.
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| Nucleosides Nucleotides Nucleic Acids 27(6):704-11.PMID: 18600529 2008
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| 18 | DHX9
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| Molecular determinants of nucleolar translocation of RNA helicase A.
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| Liu Z, Kenworthy R, Green C, Tang H.
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| Exp Cell Res 313(17):3743-54. Epub 2007 Aug 14.PMID: 17822697 2007
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| 19 | KPNA4, DHX9
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| The nuclear import of RNA helicase A is mediated by importin-alpha3.
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| Aratani S, Oishi T, Fujita H, Nakazawa M, Fujii R, Imamoto N, Yoneda Y, Fukamizu A, Nakajima T.
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| Biochem Biophys Res Commun 340(1):125-33. 2006
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| 20 | WRN, DHX9
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| Nuclear DNA helicase II (RNA helicase A) interacts with Werner syndrome helicase and stimulates its exonuclease activity.
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| Friedemann J, Grosse F, Zhang S.
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| J Biol Chem 280(35):31303-13. Epub 2005 Jul 1. 2005
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| 21 | AK8, DDX23, DDX27, DDX41, DDX42, DDX43, DDX46, DDX47, DDX49, DDX50, DDX51, DDX52, DDX53, DDX54, DDX55, DDX56, DHX15, DHX29, DHX30, DHX32, DHX33, DHX34, DHX35, DHX36, DHX37, DHX38, DHX40, DHX57, DHX8, DHX9, EIF4A2, EIF4A3
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| The human DDX and DHX gene families of putative RNA helicases.
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| Abdelhaleem M, Maltais L, Wain H.
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| Genomics 81(6):618-22. 2003
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| 22 | DHX9
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| The human RNA helicase A (DDX9) gene maps to the prostate cancer susceptibility locus at chromosome band 1q25 and its pseudogene (DDX9P) to 13q22, respectively.
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| Lee CG, Eki T, Okumura K, Nogami M, Soares Vda C, Murakami Y, Hanaoka F,Hurwitz J.
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| Somat Cell Mol Genet 25(1):33-9. 1999
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| 23 | DHX9
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| RNA helicase A is essential for normal gastrulation.
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| Lee CG, da Costa Soares V, Newberger C, Manova K, Lacy E, Hurwitz J.
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| Proc Natl Acad Sci U S A 95(23):13709-13. 1998
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| 24 | DHX9
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| Domain structure of human nuclear DNA helicase II (RNA helicase A).
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| Zhang S, Grosse F.
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| J Biol Chem 272(17):11487-94. 1997
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| 25 | DHX9
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| RNA helicase A mediates association of CBP with RNA polymerase II.
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| Nakajima T, Uchida C, Anderson SF, Lee CG, Hurwitz J, Parvin JD, MontminyM.
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| Cell 90(6):1107-12. 1997
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| 26 | DHX9
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| Report of the third international workshop on human chromosome 13 mapping 1995
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| Warburton D, et al.
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| Cytogenet Cell Genet 75 : 85-110. 1996
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| 27 | DHX9
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| Leukophysin: an RNA helicase A-related molecule identified in cytotoxic T cell granules and vesicles.
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| Abdelhaleem MM, Hameed S, Klassen D, Greenberg AH.
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| J Immunol 156(6):2026-35. 1996
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| 28 | DHX9
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| Molecular cloning of the gene encoding nuclear DNA helicase II. A bovine homologue of human RNA helicase A and Drosophila Mle protein.
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| Zhang S, et al.
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| J Biol Chem 270 : 16422-16427. 1995
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| 29 | DHX9
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| RNA annealing activity is intrinsically associated with U2AF.
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| Lee CG, Zamore PD, Green MR, Hurwitz J.
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| J Biol Chem 268(18):13472-8. 1993
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| 30 | DHX9, DHX9P
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| Human RNA helicase A is homologous to the maleless protein of Drosophila.
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| Lee CG, Hurwitz J.
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| J Biol Chem 268(22):16822-30. 1993
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| 31 | DHX9
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| A new RNA helicase isolated from HeLa cells that catalytically translocates in the 3' to 5' direction.
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| Lee CG, Hurwitz J.
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| J Biol Chem 267(7):4398-407. 1992
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