| 1 | DGCR8, DROSHA
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| DROSHA targets its own transcript to modulate alternative splicing.
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| Lee D, Nam JW, Shin C.
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| RNA NA. 2017 Apr 11. pii: rna.059808.116. doi: 10.1261/rna.059808.116. [Epub ahead of print]
2017
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| 2 | DGCR8, ERCC6, POLR2A
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| DGCR8 Mediates Repair of UV-Induced DNA Damage Independently of RNA Processing.
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| Calses PC, Dhillon KK, Tucker N, Chi Y, Huang JW, Kawasumi M, Nghiem P, Wang Y, Clurman BE, Jacquemont C, Gafken PR, Sugasawa K, Saijo M, Taniguchi T.
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| Cell Rep 19(1):162-174. doi: 10.1016/j.celrep.2017.03.021.
2017
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| 3 | DGCR8, TCF7L1
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| Noncanonical function of DGCR8 controls mESC exit from pluripotency.
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| Cirera-Salinas D, Yu J, Bodak M, Ngondo RP, Herbert KM, Ciaudo C.
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| J Cell Biol 216(2):355-366. doi: 10.1083/jcb.201606073. Epub 2017 Jan 18.
2017
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| 4 | DGCR8
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| Deficiency in DGCR8-dependent canonical microRNAs causes infertility due to multiple abnormalities during uterine development in mice.
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| Kim YS, Kim HR, Kim H, Yang SC, Park M, Yoon JA, Lim HJ, Hong SH, DeMayo FJ, Lydon JP, Choi Y, Lee DR, Song H.
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| Sci Rep 6:20242. doi: 10.1038/srep20242.
2016
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| 5 | DGCR8, DICER1, DROSHA
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| Deficiency in DGCR8-dependent canonical microRNAs causes infertility due to multiple abnormalities during uterine development in mice.
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| Kim YS, Kim HR, Kim H, Yang SC, Park M, Yoon JA, Lim HJ, Hong SH, DeMayo FJ, Lydon JP, Choi Y, Lee DR, Song H.
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| Sci Rep 6:20242. doi: 10.1038/srep20242.
2016
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| 6 | DGCR8
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| Upregulation of the double-stranded RNA binding protein DGCR8 in invasive ductal breast carcinoma.
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| Fardmanesh H, Shekari M, Movafagh A, Alizadeh Shargh S, Poursadegh Zonouzi AA, Shakerizadeh S, Poursadegh Zonouzi A, Hosseinzadeh A.
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| Gene 581(2):146-51. doi: 10.1016/j.gene.2016.01.033. Epub 2016 Jan 22.
2016
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| 7 | DGCR8
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| DGCR8 Acts as an Adaptor for the Exosome Complex to Degrade Double-Stranded Structured RNAs.
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| Macias S, Cordiner RA, Gautier P, Plass M, Cáceres JF.
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| Mol Cell 60(6):873-85. doi: 10.1016/j.molcel.2015.11.011. Epub 2015 Dec 10.
2015
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| 8 | DGCR8
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| Microprocessor complex subunit DiGeorge syndrome critical region gene 8 (Dgcr8) is required for schwann cell myelination and myelin maintenance.
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| Lin HP, Oksuz I, Hurley E, Wrabetz L, Awatramani R.
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| J Biol Chem 290(40):24294-307. doi: 10.1074/jbc.M115.636407. Epub 2015 Aug 13.
2015
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| 9 | DGCR8
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| Loss of Dgcr8-mediated microRNA expression in the kidney results in hydronephrosis and renal malformation.
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| Bartram MP, Dafinger C, Habbig S, Benzing T, Schermer B, Müller RU.
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| BMC Nephrol 16:55. doi: 10.1186/s12882-015-0053-1.
2015
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| 10 | DGCR8, DROSHA
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| Drosha-independent DGCR8/Pasha pathway regulates neuronal morphogenesis.
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| Luhur A, Chawla G, Wu YC, Li J, Sokol NS.
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| Proc Natl Acad Sci U S A 111(4):1421-6. doi: 10.1073/pnas.1318445111. Epub 2014 Jan 13.
2014
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| 11 | DGCR8
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| Expression of DGCR8-Dependent MicroRNAs Is Indispensable for Osteoclastic Development and Bone-Resorbing Activity.
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| Sugatani T, Hildreth BE 3rd, Toribio RE, Malluche HH, Hruska KA.
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| J Cell Biochem Cell Biochem. 2014 Jan 8. doi: 10.1002/jcb.24759. [Epub ahead of print]
2014
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| 12 | DGCR8
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| Decreased DGCR8 expression and miRNA dysregulation in individuals with 22q11.2 deletion syndrome.
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| Sellier C, Hwang VJ, Dandekar R, Durbin-Johnson B, Charlet-Berguerand N, Ander BP, Sharp FR, Angkustsiri K, Simon TJ, Tassone F.
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| PLoS One 9(8):e103884. doi: 10.1371/journal.pone.0103884. eCollection 2014.
2014
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| 13 | DGCR8
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| Expression of DGCR8-dependent microRNAs is indispensable for osteoclastic development and bone-resorbing activity.
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| Sugatani T, Hildreth BE 3rd, Toribio RE, Malluche HH, Hruska KA.
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| J Cell Biochem 115(6):1043-7. doi: 10.1002/jcb.24759.
2014
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| 14 | DGCR8, DROSHA
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| The core microprocessor component DiGeorge syndrome critical region 8 (DGCR8) is a nonspecific RNA-binding protein.
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| Roth BM, Ishimaru D, Hennig M.
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| J Biol Chem 288(37):26785-99. doi: 10.1074/jbc.M112.446880. Epub 2013 Jul 26.
2013
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| 15 | DGCR8
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| DGCR8-mediated disruption of miRNA biogenesis induces cellular senescence in primary fibroblasts.
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| Gómez-Cabello D, Adrados I, Gamarra D, Kobayashi H, Takatsu Y, Takatsu K, Gil J, Palmero I.
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| Aging Cell 12(5):923-31. doi: 10.1111/acel.12117. Epub 2013 Jul 19.
2013
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| 16 | DGCR8
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| DiGeorge syndrome critical region 8 (DGCR8) protein-mediated microRNA biogenesis is essential for vascular smooth muscle cell development in mice.
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| Chen Z, Wu J, Yang C, Fan P, Balazs L, Jiao Y, Lu M, Gu W, Li C, Pfeffer LM, Tigyi G, Yue J.
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| J Biol Chem 287(23):19018-28. doi: 10.1074/jbc.M112.351791. Epub 2012 Apr 17.
2012
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| 17 | DGCR8
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| Caspases cleave and inhibit the microRNA processing protein DiGeorge Critical Region 8.
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| Gong M, Chen Y, Senturia R, Ulgherait M, Faller M, Guo F.
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| Protein Sci 21(6):797-808. doi: 10.1002/pro.2062. Epub 2012 Apr 23.
2012
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| 18 | DEL22Q11, DGCR8
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| Deficiency of Dgcr8, a gene disrupted by the 22q11.2 microdeletion, results in altered short-term plasticity in the prefrontal cortex.
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| Fénelon K, Mukai J, Xu B, Hsu PK, Drew LJ, Karayiorgou M, Fischbach GD, Macdermott AB, Gogos JA.
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| Proc Natl Acad Sci U S A 108(11):4447-52. Epub 2011 Feb 28.
2011
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| 19 | DGCR8
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| DiGeorge critical region 8 (DGCR8) is a double-cysteine-ligated heme protein.
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| Barr I, Smith AT, Senturia R, Chen Y, Scheidemantle BD, Burstyn JN, Guo F.
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| J Biol Chem 286(19):16716-25. Epub 2011 Mar 21.
2011
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| 20 | DGCR8
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| Monoallelic deletion of the microRNA biogenesis gene Dgcr8 produces deficits in the development of excitatory synaptic transmission in the prefrontal cortex.
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| Schofield CM, Hsu R, Barker AJ, Gertz CC, Blelloch R, Ullian EM.
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| Neural Dev 6:11.
2011
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| 21 | DGCR8
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| Structure of the dimerization domain of DiGeorge critical region 8.
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| Senturia R, Faller M, Yin S, Loo JA, Cascio D, Sawaya MR, Hwang D, Clubb RT, Guo F.
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| Protein Sci 19(7):1354-65.
2010
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| 22 | DGCR8, DROSHA
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| Posttranscriptional crossregulation between Drosha and DGCR8.
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| Han J, Pedersen JS, Kwon SC, Belair CD, Kim YK, Yeom KH, Yang WY, Haussler D, Blelloch R, Kim VN.
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| Cell 136(1):75-84. 2009
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| 23 | DGCR8, DROSHA
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| Genome-wide identification of targets of the drosha-pasha/DGCR8 complex.
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| Kadener S, Rodriguez J, Abruzzi KC, Khodor YL, Sugino K, Marr MT 2nd, Nelson S, Rosbash M.
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| RNA 15(4):537-45. Epub 2009 Feb 17. 2009
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| 24 | DGCR8
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| Genomic analysis suggests that mRNA destabilization by the microprocessor is specialized for the auto-regulation of Dgcr8.
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| Shenoy A, Blelloch R.
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| PLoS One 4(9):e6971.
2009
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| 25 | DEL22Q11, DGCR8, DUP22Q11
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| Altered brain microRNA biogenesis contributes to phenotypic deficits in a 22q11-deletion mouse model.
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| Stark KL, Xu B, Bagchi A, Lai WS, Liu H, Hsu R, Wan X, Pavlidis P, Mills AA, Karayiorgou M, Gogos JA.
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| Nat Genet 40(6):751-60. Epub 2008 May 11. 2008
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| 26 | DGCR8
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| DGCR8 is essential for microRNA biogenesis and silencing of embryonic stem cell self-renewal.
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| Wang Y, Medvid R, Melton C, Jaenisch R, Blelloch R.
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| Nat Genet 39(3):380-5. Epub 2007 Jan 28. 2007
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| 27 | DGCR8
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| Crystal structure of human DGCR8 core.
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| Sohn SY, Bae WJ, Kim JJ, Yeom KH, Kim VN, Cho Y.
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| Nat Struct Mol Biol 14(9):847-53. Epub 2007 Aug 19.
2007
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| 28 | DGCR8
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| Nucleolar localization of DGCR8 and identification of eleven DGCR8-associated proteins.
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| Shiohama A, Sasaki T, Noda S, Minoshima S, Shimizu N.
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| Exp Cell Res 313(20):4196-207. Epub 2007 Jul 25.PMID: 17765891 2007
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| 29 | DEL22Q11, DGCR8
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| Characterization of DGCR8/Pasha, the essential cofactor for Drosha in primary miRNA processing.
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| Yeom KH, Lee Y, Han J, Suh MR, Kim VN.
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| Nucleic Acids Res 34(16):4622-9. Epub 2006 Sep 8.
2006
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| 30 | DGCR8, DICER1, DROSHA
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| MicroRNA biogenesis: isolation and characterization of the microprocessor complex.
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| Gregory RI, Chendrimada TP, Shiekhattar R.
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| Methods Mol Biol 342:33-47. Review. 2006
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| 31 | DGCR8
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| Molecular cloning and expression analysis of a novel gene DGCR8 located in the DiGeorge syndrome chromosomal region.
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| Shiohama A, Sasaki T, Noda S, Minoshima S, Shimizu N.
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| Biochem Biophys Res Commun 304(1):184-90. 2003
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| 32 | DGCR6, DGCR8, HTF9C, PRODH, RTN4R, ZDHHC8, HPI
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| Genetic variation in the 22q11 locus and susceptibility to schizophrenia.
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| Liu H, Abecasis GR, Heath SC, Knowles A, Demars S, Chen YJ, Roos JL, Rapoport JL, Gogos JA, Karayiorgou M.
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| Proc Natl Acad Sci U S A 99(26):16859-64. 2002
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