Citations for
1DERL1
Forced interaction of cell surface proteins with Derlin-1 in the endoplasmic reticulum is sufficient to induce their dislocation into the cytosol for degradation.
Cho S, Lee M, Jun Y.
Biochem Biophys Res Commun 430(2):787-92. doi: 10.1016/j.bbrc.2012.11.068. Epub 2012 Dec 1. 2013
2DERL1, SOD1
SOD1 as a molecular switch for initiating the homeostatic ER stress response under zinc deficiency.
Homma K, Fujisawa T, Tsuburaya N, Yamaguchi N, Kadowaki H, Takeda K, Nishitoh H, Matsuzawa A, Naguro I, Ichijo H.
Mol Cell 52(1):75-86. doi: 10.1016/j.molcel.2013.08.038. Epub 2013 Sep 26. 2013
3CAV1, DERL1, PTGS2
Caveolin-1 interacts with Derlin-1 and promotes ubiquitination and degradation of cyclooxygenase-2 via collaboration with p97 complex.
Chen SF, Wu CH, Lee YM, Tam K, Tsai YC, Liou JY, Shyue SK.
J Biol Chem 288(46):33462-9. doi: 10.1074/jbc.M113.521799. Epub 2013 Oct 2. 2013
4DERL1
Role of Derlin-1 protein in proteostasis regulation of ATP-sensitive potassium channels.
Wang F, Olson EM, Shyng SL.
J Biol Chem 287(13):10482-93. doi: 10.1074/jbc.M111.312223. Epub 2012 Feb 6. 2012
5APOB, DERL1, FAF2
Derlin-1 and UBXD8 are engaged in dislocation and degradation of lipidated ApoB-100 at lipid droplets.
Suzuki M, Otsuka T, Ohsaki Y, Cheng J, Taniguchi T, Hashimoto H, Taniguchi H, Fujimoto T.
Mol Biol Cell 23(5):800-10. doi: 10.1091/mbc.E11-11-0950. Epub 2012 Jan 11. 2012
6DERL1, DNAJB11, DNAJB9, DNAJC10
ERdj4 protein is a soluble endoplasmic reticulum (ER) DnaJ family protein that interacts with ER-associated degradation machinery.
Lai CW, Otero JH, Hendershot LM, Snapp E.
J Biol Chem 287(11):7969-78. doi: 10.1074/jbc.M111.311290. Epub 2012 Jan 20. 2012
7DERL1, DERL2, DERL3, ROMO1, SELK, VCP, VIMP
Selenoprotein K binds multiprotein complexes and is involved in the regulation of endoplasmic reticulum homeostasis.
Shchedrina VA, Everley RA, Zhang Y, Gygi SP, Hatfield DL, Gladyshev VN.
J Biol Chem 286(50):42937-48. doi: 10.1074/jbc.M111.310920. Epub 2011 Oct 20. 2011
8DERL1, VCP
Derlin-1 and p97/valosin-containing protein mediate the endoplasmic reticulum-associated degradation of human V2 vasopressin receptors.
Schwieger I, Lautz K, Krause E, Rosenthal W, Wiesner B, Hermosilla R.
Mol Pharmacol 73(3):697-708. Epub 2007 Nov 29. 2008
9BCAP31, DERL1, SEC61B, TRAM1
BAP31 interacts with Sec61 translocons and promotes retrotranslocation of CFTRDeltaF508 via the derlin-1 complex.
Wang B, Heath-Engel H, Zhang D, Nguyen N, Thomas DY, Hanrahan JW, Shore GC.
Cell 133(6):1080-92. 2008
10DERL1
Identification of derlin-1 as a novel growth factor-responsive endothelial antigen by suppression subtractive hybridization.
Ran Y, Jiang Y, Zhong X, Zhou Z, Liu H, Hu H, Lou JN, Yang Z.
Biochem Biophys Res Commun 348(4):1272-8. Epub 2006 Aug 7. 2006
11CFTR, DERL1
Derlin-1 promotes the efficient degradation of the cystic fibrosis transmembrane conductance regulator (CFTR) and CFTR folding mutants.
Sun F, Zhang R, Gong X, Geng X, Drain PF, Frizzell RA.
J Biol Chem 281(48):36856-63. Epub 2006 Sep 5. 2006
12DERL1, VCP, VIMP
A membrane protein complex mediates retro-translocation from the ER lumen into the cytosol.
Ye Y, Shibata Y, Yun C, Ron D, Rapoport TA.
Nature 429(6994):841-7. 2004
13DERL1, VCP, VIMP
A membrane protein required for dislocation of misfolded proteins from the ER.
Lilley BN, Ploegh HL.
Nature 429(6994):834-40. 2004