| 1 | CELF1, DEK
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| Systems analysis identifies melanoma-enriched pro-oncogenic networks controlled by the RNA binding protein CELF1.
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| Cifdaloz M, Osterloh L, Graña O, Riveiro-Falkenbach E, Ximénez-Embún P, Muñoz J, Tejedo C, Calvo TG, Karras P, Olmeda D, Miñana B, Gómez-López G, Cañon E, Eyras E, Guo H, Kappes F, Ortiz-Romero PL, Rodríguez-Peralto JL, Megías D, Valcárcel J, Soengas MS.
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| Nat Commun 8(1):2249. doi: 10.1038/s41467-017-02353-y.
2017
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| 2 | DEK
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| DEK proto-oncogene is highly expressed in astrocytic tumors and regulates glioblastoma cell proliferation and apoptosis.
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| Feng T, Liu Y, Li C, Li Z, Cai H.
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| Tumour Biol 39(7):1010428317716248. doi: 10.1177/1010428317716248.
2017
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| 3 | DEK
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| DEK protein overexpression predicts poor prognosis in pancreatic ductal adenocarcinoma.
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| Sun J, Bi F, Yang Y, Zhang Y, Jin A, Li J, Lin Z.
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| Oncol Rep 37(2):857-864. doi: 10.3892/or.2016.5302. Epub 2016 Dec 8.
2017
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| 4 | DEK
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| Critical role of DEK and its regulation in tumorigenesis and metastasis of hepatocellular carcinoma.
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| Yu L, Huang X, Zhang W, Zhao H, Wu G, Lv F, Shi L, Teng Y.
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| Oncotarget 7(18):26844-55. doi: 10.18632/oncotarget.8565.
2016
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| 5 | DEK, NUP214
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| The DEK oncoprotein and its emerging roles in gene regulation.
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| Sandén C, Gullberg U.
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| Leukemia eukemia. 2015 Mar 13. doi: 10.1038/leu.2015.72. [Epub ahead of print]
2015
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| 6 | DEK, KLF1
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| The DEK Oncoprotein Is a Critical Component of the EKLF/KLF1 Enhancer in Erythroid Cells.
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| Lohmann F, Dangeti M, Soni S, Chen X, Planutis A, Baron MH, Choi K, Bieker JJ.
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| Mol Cell Biol 35(21):3726-38. doi: 10.1128/MCB.00382-15. Epub 2015 Aug 24.
2015
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| 7 | DEK
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| The human oncoprotein and chromatin architectural factor DEK counteracts DNA replication stress.
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| Deutzmann A, Ganz M, Schönenberger F, Vervoorts J, Kappes F, Ferrando-May E.
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| Oncogene 34(32):4270-7. doi: 10.1038/onc.2014.346. Epub 2014 Oct 27.
2015
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| 8 | DEK
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| The DEK oncoprotein binds to highly and ubiquitously expressed genes with a dual role in their transcriptional regulation.
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| Sandén C, Järvstråt L, Lennartsson A, Brattås PL, Nilsson B, Gullberg U.
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| Mol Cancer 13:215. doi: 10.1186/1476-4598-13-215.
2014
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| 9 | DEK, TERT
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| Chromatin redistribution of the DEK oncoprotein represses hTERT transcription in leukemias.
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| Karam M, Thenoz M, Capraro V, Robin JP, Pinatel C, Lancon A, Galia P, Sibon D, Thomas X, Ducastelle-Lepretre S, Nicolini F, El-Hamri M, Chelghoun Y, Wattel E, Mortreux F.
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| Neoplasia 16(1):21-30.
2014
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| 10 | DEK
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| Intercellular trafficking of the nuclear oncoprotein DEK.
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| Saha AK, Kappes F, Mundade A, Deutzmann A, Rosmarin DM, Legendre M, Chatain N, Al-Obaidi Z, Adams BS, Ploegh HL, Ferrando-May E, Mor-Vaknin N, Markovitz DM.
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| Proc Natl Acad Sci U S A 110(17):6847-52. doi: 10.1073/pnas.1220751110. Epub 2013 Apr 8.
2013
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| 11 | CEBPA, DEK
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| C/EBPα and DEK coordinately regulate myeloid differentiation.
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| Koleva RI, Ficarro SB, Radomska HS, Carrasco-Alfonso MJ, Alberta JA, Webber JT, Luckey CJ, Marcucci G, Tenen DG, Marto JA.
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| Blood 119(21):4878-88. doi: 10.1182/blood-2011-10-383083. Epub 2012 Apr 3.
2012
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| 12 | DEK
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| DEK regulates hematopoietic stem engraftment and progenitor cell proliferation.
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| Broxmeyer HE, Kappes F, Mor-Vaknin N, Legendre M, Kinzfogl J, Cooper S, Hangoc G, Markovitz DM.
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| Stem Cells Dev 21(9):1449-54. doi: 10.1089/scd.2011.0451. Epub 2011 Oct 27.
2012
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| 13 | DEK
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| The human DEK oncogene regulates DNA damage response signaling and repair.
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| Kavanaugh GM, Wise-Draper TM, Morreale RJ, Morrison MA, Gole B, Schwemberger S, Tichy ED, Lu L, Babcock GF, Wells JM, Drissi R, Bissler JJ, Stambrook PJ, Andreassen PR, Wiesmüller L, Wells SI.
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| Nucleic Acids Res 39(17):7465-76. doi: 10.1093/nar/gkr454. Epub 2011 Jun 7.
2011
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| 14 | DEK, NUP214
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| A histone chaperone, DEK, transcriptionally coactivates a nuclear receptor.
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| Sawatsubashi S, Murata T, Lim J, Fujiki R, Ito S, Suzuki E, Tanabe M, Zhao Y, Kimura S, Fujiyama S, Ueda T, Umetsu D, Ito T, Takeyama K, Kato S.
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| Genes Dev 24(2):159-70. Epub 2009 Dec 29.PMID: 20040570 2010
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| 15 | DEK
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| The oncogene DEK promotes leukemic cell survival and is downregulated by both Nutlin-3 and chlorambucil in B-chronic lymphocytic leukemic cells.
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| Secchiero P, Voltan R, di Iasio MG, Melloni E, Tiribelli M, Zauli G.
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| Clin Cancer Res 16(6):1824-33. Epub 2010 Mar 9.PMID: 20215548 2010
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| 16 | DEK
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| Clinicopathological significance of DEK overexpression in serous ovarian tumors.
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| Han S, Xuan Y, Liu S, Zhang M, Jin D, Jin R, Lin Z.
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| Pathol Int 59(7):443-7.PMID: 19563407 2009
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| 17 | DEK
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| Overexpression of the cellular DEK protein promotes epithelial transformation in vitro and in vivo.
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| Wise-Draper TM, Mintz-Cole RA, Morris TA, Simpson DS, Wikenheiser-Brokamp KA, Currier MA, Cripe TP, Grosveld GC, Wells SI.
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| Cancer Res 69(5):1792-9. Epub 2009 Feb 17.PMID: 19223548 2009
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| 18 | DEK
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| DEK proto-oncogene expression interferes with the normal epithelial differentiation program.
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| Wise-Draper TM, Morreale RJ, Morris TA, Mintz-Cole RA, Hoskins EE, Balsitis SJ, Husseinzadeh N, Witte DP, Wikenheiser-Brokamp KA, Lambert PF, Wells SI.
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| Am J Pathol 174(1):71-81. Epub 2008 Nov 26.PMID: 19036808 2009
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| 19 | NUP214, DEK
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| Identification of a novel and myeloid specific role of the leukemia-associated fusion protein DEK-NUP214 leading to increased protein synthesis.
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| Ageberg M, Drott K, Olofsson T, Gullberg U, Lindmark A.
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| Genes Chromosomes Cancer 47(4):276-87. 2008
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| 20 | DEK
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| DEK is a poly(ADP-ribose) acceptor in apoptosis and mediates resistance to genotoxic stress.
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| Kappes F, Fahrer J, Khodadoust MS, Tabbert A, Strasser C, Mor-Vaknin N, Moreno-Villanueva M, Bürkle A, Markovitz DM, Ferrando-May E.
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| Mol Cell Biol 28(10):3245-57. Epub 2008 Mar 10.PMID: 18332104 2008
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| 21 | DEK,PARP1,SET
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| SET and PARP1 remove DEK from chromatin to permit access by the transcription machinery.
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| Gamble MJ, Fisher RP.
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| Nat Struct Mol Biol 14(6):548-55. Epub 2007 May 27. 2007
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| 22 | DEK
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| The involvement of cellular proliferation status in the expression of the human proto-oncogene DEK.
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| Ageberg M, Gullberg U, Lindmark A.
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| Haematologica 91(2):268-9. 2006
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| 23 | DEK, EP300, KAT2B
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| Regulation of histone acetyltransferase activity of p300 and PCAF by proto-oncogene protein DEK.
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| Ko SI, Lee IS, Kim JY, Kim SM, Kim DW, Lee KS, Woo KM, Baek JH, Choo JK, Seo SB.
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| FEBS Lett 580(13):3217-22. Epub 2006 May 4. 2006
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| 24 | DEK
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| DEK Expression is controlled by E2F and deregulated in diverse tumor types.
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| Carro MS, Spiga FM, Quarto M, Di Ninni V, Volorio S, Alcalay M, Muller H.
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| Cell Cycle 5(11):1202-7. Epub 2006 Jun 1. 2006
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| 25 | DEK
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| Intron removal requires proofreading of U2AF/3' splice site recognition by DEK.
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| Soares LM, Zanier K, Mackereth C, Sattler M, Valcarcel J.
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| Science 312(5782):1961-5. 2006
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| 26 | DEK
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| The SAF-box domain of chromatin protein DEK.
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| Bohm F, Kappes F, Scholten I, Richter N, Matsuo H, Knippers R, Waldmann T.
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| Nucleic Acids Res 33(3):1101-10. Print 2005. 2005
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| 27 | DEK
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| Distribution of the chromatin protein DEK distinguishes active and inactive CD21/CR2 gene in pre- and mature B lymphocytes.
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| Hu HG, Illges H, Gruss C, Knippers R.
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| Int Immunol 17(6):789-96. Epub 2005 May 20. 2005
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| 28 | DEK
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| Gains and overexpression identify DEK and E2F3 as targets of chromosome 6p gains in retinoblastoma.
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| Grasemann C, Gratias S, Stephan H, Schuler A, Schramm A, Klein-Hitpass L, Rieder H, Schneider S, Kappes F, Eggert A, Lohmann DR.
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| Oncogene 24(42):6441-9. 2005
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| 29 | DEK
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| Functional domains of the ubiquitous chromatin protein DEK.
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| Kappes F, Scholten I, Richter N, Gruss C, Waldmann T.
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| Mol Cell Biol 24(13):6000-10. 2004
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| 30 | DEK
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| Phosphorylation by protein kinase CK2 changes the DNA binding properties of the human chromatin protein DEK.
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| Kappes F, Damoc C, Knippers R, Przybylski M, Pinna LA, Gruss C.
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| Mol Cell Biol 24(13):6011-20. 2004
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| 31 | DEK
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| Transcriptional activation by AP-2alpha is modulated by the oncogene DEK.
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| Campillos M, Garcia MA, Valdivieso F, Vazquez J.
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| Nucleic Acids Res 31(5):1571-5. 2003
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| 32 | DEK, IGFBP1, LGALS4, LY6E, UGT2B4
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| Identification and characterization of genes associated with human hepatocellular carcinogenesis.
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| Kondoh N, Wakatsuki T, Ryo A, Hada A, Aihara T, Horiuchi S, Goseki N, Matsubara O, Takenaka K, Shichita M, Tanaka K, Shuda M, Yamamoto M.
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| Cancer Res 59(19):4990-6. 1999
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| 33 | DEK
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| Establishment of a novel human myeloid leukaemia cell line (FKH-1) with t(6;9)(p23;q34) and the expression of dek-can chimaeric transcript.
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| Hamaguchi H, et al.
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| Br J Haematol 102 : 1249-1256. 1998
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| 34 | DEK
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| DEK, an autoantigen involved in a chromosomal translocation in acute myelogenous leukemia, binds to the HIV-2 enhancer.
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| Fu GK, Grosveld G, Markovitz DM.
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| Proc Natl Acad Sci U S A 94(5):1811-5. 1997
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| 35 | EDN1, GMPR, SCA1, DEK
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| An integrated map of human chromosome 6p23.
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| Olavesen MG, et al.
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| Genome Res 5 : 342-358. 1995
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| 36 | DEK, NUP214, CAN
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| The translocation (6;9), associated with a specific subtype of acute myeloid leukemia, results in the fusion of two genes, dek and can, and the expression of a chimeric, leukemia-specific dek-can mRNA.
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| von Lindern M, et al.
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| Mol Cell Biol 12 : 1687-1697. 1992
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| 37 | NUP214, DEK, CAN
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| The translocation (6;9)(p23;q34) shows consistent rearrangement of two genes and defines a myeloproliferative disorder with specific clinical features.
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| Soekarman D, et al.
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| Blood 79 : 2990-2997. 1992
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| 38 | NUP214, DEK, CAN
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| Characterization of the translocation breakpoint sequences of two DEK-CAN fusion genes present in t(6;9) acute myeloid leukemia and a SET-CAN fusion gene found in a case of acute undifferentiated leukemia.
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| Von Lindern M, et al.
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| Genes Chromosomes Cancer 5 : 227-234. 1992
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| 39 | NUP214, D9S46, DEK,CAN
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| The (6;9) chromosome translocation, associated with a specific subtype of acute nonlymphocytic leukemia, leads to aberrant transcription of a target gene on 9q34.
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| von Lindern M, et al.
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| Mol Cell Biol 10 : 4016-4026. 1990
|