| 1 | DEFB103B, IL1F7
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| Human β-defensin-3 increases the expression of interleukin-37 through CCR6 in human keratinocytes.
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| Smithrithee R, Niyonsaba F, Kiatsurayanon C, Ushio H, Ikeda S, Okumura K, Ogawa H.
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| J Dermatol Sci 77(1):46-53. doi: 10.1016/j.jdermsci.2014.12.001. Epub 2014 Dec 10.
2015
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| 2 | DEFB103B
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| Human β-defensin-3 inhibits migration of colon cancer cells via downregulation of metastasis-associated 1 family, member 2 expression.
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| Uraki S, Sugimoto K, Shiraki K, Tameda M, Inagaki Y, Ogura S, Kasai C, Nojiri K, Yoneda M, Yamamoto N, Takei Y, Nobori T, Ito M.
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| Int J Oncol 45(3):1059-64. doi: 10.3892/ijo.2014.2507. Epub 2014 Jun 20. Erratum in: Int J Oncol. 2015 Apr;46(4):1858.
2014
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| 3 | DEFB103B
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| Human β-defensin-3 correlates with muscle fibre degeneration in idiopathic inflammatory myopathies.
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| Güttsches AK, Jacobsen F, Theiss C, Rittig A, Rehimi R, Kley RA, Vorgerd M, Steinstraesser L.
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| Innate Immun 20(1):49-60. doi: 10.1177/1753425913481820. Epub 2013 Apr 22.
2014
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| 4 | DEFB103B
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| Molecular and functional analysis of human β-defensin 3 action at melanocortin receptors.
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| Nix MA, Kaelin CB, Ta T, Weis A, Morton GJ, Barsh GS, Millhauser GL.
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| Chem Biol 20(6):784-95. doi: 10.1016/j.chembiol.2013.04.015.
2013
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| 5 | CXCR4, DEFB103B
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| Human β-defensin-3 structure motifs that are important in CXCR4 antagonism.
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| Feng Z, Dubyak GR, Jia X, Lubkowski JT, Weinberg A.
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| FEBS J 280(14):3365-75. doi: 10.1111/febs.12328. Epub 2013 Jun 7.
2013
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| 6 | DEFB103B, MC1R
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| Melanocortin-1 receptor-mediated signalling pathways activated by NDP-MSH and HBD3 ligands.
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| Beaumont KA, Smit DJ, Liu YY, Chai E, Patel MP, Millhauser GL, Smith JJ, Alewood PF, Sturm RA.
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| Pigment Cell Melanoma Res 25(3):370-4. doi: 10.1111/j.1755-148X.2012.00990.x. Epub 2012 Mar 19.
2012
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| 7 | DEFB103B
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| Membrane damage and repair in primary monocytes exposed to human β-defensin-3.
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| Lioi AB, Rodriguez AL, Funderburg NT, Feng Z, Weinberg A, Sieg SF.
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| J Leukoc Biol 92(5):1083-91. doi: 10.1189/jlb.0112046. Epub 2012 Jul 26.
2012
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| 8 | DEFB103B, MYD88, TICAM1
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| Human β-defensin 3 affects the activity of pro-inflammatory pathways associated with MyD88 and TRIF.
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| Semple F, MacPherson H, Webb S, Cox SL, Mallin LJ, Tyrrell C, Grimes GR, Semple CA, Nix MA, Millhauser GL, Dorin JR.
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| Eur J Immunol 41(11):3291-300. doi: 10.1002/eji.201141648. Epub 2011 Sep 6.
2011
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| 9 | DEFB103B
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| High-Glucose Environment Inhibits p38MAPK Signaling and Reduces Human β-Defensin-3 Expression [corrected] in Keratinocytes.
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| Lan CC, Wu CS, Huang SM, Kuo HY, Wu IH, Wen CH, Chai CY, Fang AH, Chen GS.
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| Mol Med 17(7-8):771-9. doi: 10.2119/molmed.2010.00091. Epub 2011 Mar 22. Erratum in: Mol Med. 2011 Sep-Oct;17(9-10):1129.
2011
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| 10 | DEFB103B
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| Human beta-defensin 3 has immunosuppressive activity in vitro and in vivo.
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| Semple F, Webb S, Li HN, Patel HB, Perretti M, Jackson IJ, Gray M, Davidson DJ, Dorin JR.
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| Eur J Immunol 40(4):1073-8. doi: 10.1002/eji.200940041.
2010
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| 11 | DEFB103B, DEFB4A
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| The role of human beta defensins 2 and 3 in the second trimester amniotic fluid in predicting preterm labor and premature rupture of membranes.
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| Iavazzo C, Tassis K, Gourgiotis D, Boutsikou M, Baka S, Hassiakos D, Hadjithomas A, Botsis D, Malamitsi-Puchner A.
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| Arch Gynecol Obstet 281(5):793-9. doi: 10.1007/s00404-009-1155-4. Epub 2009 Jun 25.
2010
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| 12 | DEFB103B
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| Histamine induces human beta-defensin-3 production in human keratinocytes.
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| Ishikawa T, Kanda N, Hau CS, Tada Y, Watanabe S.
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| J Dermatol Sci 56(2):121-7. doi: 10.1016/j.jdermsci.2009.07.012. Epub 2009 Sep 5.
2009
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| 13 | DEFB103B
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| Osteoblasts participate in the innate immunity of the bone by producing human beta defensin-3.
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| Varoga D, Wruck CJ, Tohidnezhad M, Brandenburg L, Paulsen F, Mentlein R, Seekamp A, Besch L, Pufe T.
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| Histochem Cell Biol 131(2):207-18. doi: 10.1007/s00418-008-0522-8. Epub 2008 Oct 17.
2009
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| 14 | DEFB103B
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| Identification and Biological Characterization of Mouse beta-defensin 14, the orthologue of human beta-defensin 3.
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| Röhrl J, Yang D, Oppenheim JJ, Hehlgans T.
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| J Biol Chem 283(9):5414-9. doi: 10.1074/jbc.M709103200. Epub 2007 Dec 31.
2008
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| 15 | DEFB103B
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| Human -defensin-3 activates professional antigen-presenting cells via Toll-like receptors 1 and 2.
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| Funderburg N, Lederman MM, Feng Z, Drage MG, Jadlowsky J, Harding CV, Weinberg A, Sieg SF.
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| Proc Natl Acad Sci U S A 104(47):18631-5. Epub 2007 Nov 15.
2007
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| 16 | DEFB103B
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| Signal transduction and nuclear responses in Staphylococcus aureus-induced expression of human beta-defensin 3 in skin keratinocytes.
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| Menzies BE, Kenoyer A.
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| Infect Immun 74(12):6847-54. Epub 2006 Sep 5.
2006
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| 17 | DEFB103B
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| Lipid-specific membrane activity of human beta-defensin-3.
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| Böhling A, Hagge SO, Roes S, Podschun R, Sahly H, Harder J, Schröder JM, Grötzinger J, Seydel U, Gutsmann T.
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| Biochemistry 45(17):5663-70.
2006
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| 18 | DEFB103B
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| Differential expression of the natural antimicrobials, beta-defensins 3 and 4, in human endometrium.
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| King AE, Fleming DC, Critchley HO, Kelly RW.
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| J Reprod Immunol 59(1):1-16.
2003
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| 19 | DEFB103A, DEFB103B
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| Isolation and characterization of human beta -defensin-3, a novel human inducible peptide antibiotic.
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| Harder J, Bartels J, Christophers E, Schroder JM.
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| J Biol Chem 276(8):5707-13. 2001
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| 20 | DEFB103B
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| Discovery of new human beta-defensins using a genomics-based approach.
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| Jia HP, Schutte BC, Schudy A, Linzmeier R, Guthmiller JM, Johnson GK, Tack BF, Mitros JP, Rosenthal A, Ganz T, McCray PB Jr.
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| Gene 263(1-2):211-8.
2001
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