Citations for
1DEFB1
Reduction of disulphide bonds unmasks potent antimicrobial activity of human β-defensin 1.
Schroeder BO, Wu Z, Nuding S, Groscurth S, Marcinowski M, Beisner J, Buchner J, Schaller M, Stange EF, Wehkamp J.
Nature 469(7330):419-23. 2011
2DEFA1, DEFB1
Cyclic and acyclic defensins inhibit human immunodeficiency virus type-1 replication by different mechanisms.
Seidel A, Ye Y, de Armas LR, Soto M, Yarosh W, Marcsisin RA, Tran D, Selsted ME, Camerini D.
PLoS One 5(3):e9737. 2010
3DEFB1
Roles of human beta-defensins in innate immune defense at the ocular surface: arming and alarming corneal and conjunctival epithelial cells.
Garreis F, Schlorf T, Worlitzsch D, Steven P, Bräuer L, Jäger K, Paulsen FP.
Histochem Cell Biol 134(1):59-73. Epub 2010 Jun 5. 2010
4DEFB1
Analysis of DEFB1 regulatory SNPs in cystic fibrosis patients from North-Eastern Italy.
Segat L, Morgutti M, Athanasakis E, Trevisiol C, Amaddeo A, Poli F, Crovella S.
Int J Immunogenet 37(3):169-75. Epub 2010 Feb 24. 2010
5DEFA1, DEFB1
Human defensins activate monocyte-derived dendritic cells, promote the production of proinflammatory cytokines, and up-regulate the surface expression of CD91.
Presicce P, Giannelli S, Taddeo A, Villa ML, Della Bella S.
J Leukoc Biol 86(4):941-8. 2009
6DEFB1, PAX2
PAX2 oncogene negatively regulates the expression of the host defense peptide human beta defensin-1 in prostate cancer.
Bose SK, Gibson W, Bullard RS, Donald CD.
Mol Immunol 46(6):1140-8. Epub 2008 Dec 31. 2009
7DEFB1
Association of beta-defensin 1 single nucleotide polymorphisms with Crohn's disease.
Kocsis AK, Lakatos PL, Somogyvári F, Fuszek P, Papp J, Fischer S, Szamosi T, Lakatos L, Kovacs A, Hofner P, Mándi Y.
Scand J Gastroenterol 43(3):299-307. 2008
8DEFB1
The signature of long-standing balancing selection at the human defensin beta-1 promoter.
Cagliani R, Fumagalli M, Riva S, Pozzoli U, Comi GP, Menozzi G, Bresolin N, Sironi M.
Genome Biol 9(9):R143. Epub 2008 Sep 25. 2008
9DEFA1, DEFA3, DEFA4, DEFA5, DEFA6, DEFB1, DEFB103A, DEFB4A
Human defensin gene copy number polymorphisms: comprehensive analysis of independent variation in alpha- and beta-defensin regions at 8p22-p23.
Linzmeier RM, Ganz T.
Genomics 86(4):423-30. 2005
10DEFB1
Expression of human beta-defensin 1 mRNA in human palatine tonsil.
Chae SW, Lee SH, Cho JH, Lee HM, Choi G, Hwang SJ.
Acta Otolaryngol 121(3):414-8. 2001
11DEFB1, DEFB4A
A 450-kb contig of defensin genes on human chromosome 8p23.
Linzmeier R, et al.
Gene 233(1-2):205-11 1999
12DEFB1, DEFB4A
Production of beta-defensins by human airway epithelia.
Singh PK, et al.
Proc Natl Acad Sci U S A 95(25):14961-6. 1998
13DEFA1, DEFB1
The human beta-defensin-1 and alpha-defensins are encoded by adjacent genes: two peptide families with differing disulfide topology share a common ancestry.
Liu L, Zhao C, Heng HH, Ganz T.
Genomics 43(3):316-20. 1997
14DEFB1
hBD-1 : a novel beta-defensin from human plasma.
Bensch KW, et al.
FEBS Lett 368 : 331-335. 1995