1 | DEFB1
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| Reduction of disulphide bonds unmasks potent antimicrobial activity of human β-defensin 1.
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| Schroeder BO, Wu Z, Nuding S, Groscurth S, Marcinowski M, Beisner J, Buchner J, Schaller M, Stange EF, Wehkamp J.
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| Nature 469(7330):419-23.
2011
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2 | DEFA1, DEFB1
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| Cyclic and acyclic defensins inhibit human immunodeficiency virus type-1 replication by different mechanisms.
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| Seidel A, Ye Y, de Armas LR, Soto M, Yarosh W, Marcsisin RA, Tran D, Selsted ME, Camerini D.
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| PLoS One 5(3):e9737.
2010
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3 | DEFB1
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| Roles of human beta-defensins in innate immune defense at the ocular surface: arming and alarming corneal and conjunctival epithelial cells.
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| Garreis F, Schlorf T, Worlitzsch D, Steven P, Bräuer L, Jäger K, Paulsen FP.
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| Histochem Cell Biol 134(1):59-73. Epub 2010 Jun 5.
2010
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4 | DEFB1
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| Analysis of DEFB1 regulatory SNPs in cystic fibrosis patients from North-Eastern Italy.
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| Segat L, Morgutti M, Athanasakis E, Trevisiol C, Amaddeo A, Poli F, Crovella S.
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| Int J Immunogenet 37(3):169-75. Epub 2010 Feb 24.
2010
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5 | DEFA1, DEFB1
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| Human defensins activate monocyte-derived dendritic cells, promote the production of proinflammatory cytokines, and up-regulate the surface expression of CD91.
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| Presicce P, Giannelli S, Taddeo A, Villa ML, Della Bella S.
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| J Leukoc Biol 86(4):941-8.
2009
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6 | DEFB1, PAX2
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| PAX2 oncogene negatively regulates the expression of the host defense peptide human beta defensin-1 in prostate cancer.
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| Bose SK, Gibson W, Bullard RS, Donald CD.
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| Mol Immunol 46(6):1140-8. Epub 2008 Dec 31.
2009
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7 | DEFB1
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| Association of beta-defensin 1 single nucleotide polymorphisms with Crohn's disease.
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| Kocsis AK, Lakatos PL, Somogyvári F, Fuszek P, Papp J, Fischer S, Szamosi T, Lakatos L, Kovacs A, Hofner P, Mándi Y.
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| Scand J Gastroenterol 43(3):299-307.
2008
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8 | DEFB1
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| The signature of long-standing balancing selection at the human defensin beta-1 promoter.
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| Cagliani R, Fumagalli M, Riva S, Pozzoli U, Comi GP, Menozzi G, Bresolin N, Sironi M.
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| Genome Biol 9(9):R143. Epub 2008 Sep 25.
2008
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9 | DEFA1, DEFA3, DEFA4, DEFA5, DEFA6, DEFB1, DEFB103A, DEFB4A
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| Human defensin gene copy number polymorphisms: comprehensive analysis of independent variation in alpha- and beta-defensin regions at 8p22-p23.
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| Linzmeier RM, Ganz T.
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| Genomics 86(4):423-30. 2005
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10 | DEFB1
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| Expression of human beta-defensin 1 mRNA in human palatine tonsil.
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| Chae SW, Lee SH, Cho JH, Lee HM, Choi G, Hwang SJ.
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| Acta Otolaryngol 121(3):414-8. 2001
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11 | DEFB1, DEFB4A
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| A 450-kb contig of defensin genes on human chromosome 8p23.
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| Linzmeier R, et al.
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| Gene 233(1-2):205-11 1999
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12 | DEFB1, DEFB4A
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| Production of beta-defensins by human airway epithelia.
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| Singh PK, et al.
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| Proc Natl Acad Sci U S A 95(25):14961-6. 1998
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13 | DEFA1, DEFB1
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| The human beta-defensin-1 and alpha-defensins are encoded by adjacent genes: two peptide families with differing disulfide topology share a common ancestry.
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| Liu L, Zhao C, Heng HH, Ganz T.
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| Genomics 43(3):316-20. 1997
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14 | DEFB1
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| hBD-1 : a novel beta-defensin from human plasma.
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| Bensch KW, et al.
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| FEBS Lett 368 : 331-335. 1995
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