| 1 | DEFA1, DEFA3, DEFA4
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| Human α-defensin (DEFA) gene expression helps to characterise benign and malignant salivary gland tumours.
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| Winter J, Pantelis A, Kraus D, Reckenbeil J, Reich R, Jepsen S, Fischer HP, Allam JP, Novak N, Wenghoefer M.
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| BMC Cancer 12:465. doi: 10.1186/1471-2407-12-465.
2012
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| 2 | DEFA1, IL8
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| Differential effects of human neutrophil peptide-1 on growth factor and interleukin-8 production by human lung fibroblasts and epithelial cells.
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| Amenomori M, Mukae H, Ishimatsu Y, Sakamoto N, Kakugawa T, Hara A, Hara S, Fujita H, Ishimoto H, Hayashi T, Kohno S.
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| Exp Lung Res 36(7):411-9. 2010
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| 3 | DEFA1, DEFB1
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| Cyclic and acyclic defensins inhibit human immunodeficiency virus type-1 replication by different mechanisms.
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| Seidel A, Ye Y, de Armas LR, Soto M, Yarosh W, Marcsisin RA, Tran D, Selsted ME, Camerini D.
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| PLoS One 5(3):e9737.
2010
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| 4 | DEFA1
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| Functional interaction of human neutrophil peptide-1 with the cell wall precursor lipid II.
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| de Leeuw E, Li C, Zeng P, Li C, Diepeveen-de Buin M, Lu WY, Breukink E, Lu W.
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| FEBS Lett 584(8):1543-8. Epub 2010 Mar 7.
2010
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| 5 | DEFA1
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| Intratumoral expression of mature human neutrophil peptide-1 mediates antitumor immunity in mice.
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| Wang YS, Li D, Shi HS, Wen YJ, Yang L, Xu N, Chen XC, Chen X, Chen P, Li J, Deng HX, Wang CT, Xie G, Huang S, Mao YQ, Chen LJ, Zhao X, Wei YQ.
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| Clin Cancer Res 15(22):6901-11. Epub 2009 Oct 27.
2009
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| 6 | DEFA1, DEFB1
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| Human defensins activate monocyte-derived dendritic cells, promote the production of proinflammatory cytokines, and up-regulate the surface expression of CD91.
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| Presicce P, Giannelli S, Taddeo A, Villa ML, Della Bella S.
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| J Leukoc Biol 86(4):941-8.
2009
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| 7 | DEFA1, DEFA3, DEFA@, DUP8P23
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| High-resolution mapping of the 8p23.1 beta-defensin cluster reveals strictly concordant copy number variation of all genes.
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| Groth M, Szafranski K, Taudien S, Huse K, Mueller O, Rosenstiel P, Nygren AO, Schreiber S, Birkenmeier G, Platzer M.
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| Hum Mutat 29(10):1247-54. 2008
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| 8 | DEFA1
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| Molecular determinants for the interaction of human neutrophil alpha defensin 1 with its propeptide.
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| Zou G, de Leeuw E, Lubkowski J, Lu W.
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| J Mol Biol 381(5):1281-91. Epub 2008 Jun 28.
2008
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| 9 | DEFA1
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| Suppression of hepatic glucose production by human neutrophil alpha-defensins through a signaling pathway distinct from insulin.
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| Liu HY, Collins QF, Moukdar F, Zhuo D, Han J, Hong T, Collins S, Cao W.
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| J Biol Chem 283(18):12056-63. Epub 2008 Mar 17.
2008
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| 10 | KMS, DUP8P23, DEFA1, DEFA3
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| Failure to detect an 8p22-8p23.1 duplication in patients with Kabuki (Niikawa-Kuroki) syndrome.
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| Sanlaville D, Genevieve D, Bernardin C, Amiel J, Baumann C, de Blois MC, Cormier-Daire V, Gerard B, Gerard M, Le Merrer M, Parent P, Prieur F, Prieur M, Raoul O, Toutain A, Verloes A, Viot G, Romana S, Munnich A, Lyonnet S, Vekemans M, Turleau C.
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| Eur J Hum Genet 13(5):690-3. 2005
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| 11 | DEFA1, DEFA3, DEFT1P
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| Copy number polymorphism and expression level variation of the human alpha-defensin genes DEFA1 and DEFA3.
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| Aldred PM, Hollox EJ, Armour JA.
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| Hum Mol Genet 14(14):2045-52. Epub 2005 Jun 8. 2005
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| 12 | DUP8P23, DEFA1
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| Duplications and copy number variants of 8p23.1 are cytogenetically indistinguishable but distinct at the molecular level.
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| Barber JC, Maloney V, Hollox EJ, Stuke-Sontheimer A, du Bois G, Daumiller E, Klein-Vogler U, Dufke A, Armour JA, Liehr T.
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| Eur J Hum Genet 13(10):1131-1136. 2005
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| 13 | DEFA1, DEFA3, DEFA4, DEFA5, DEFA6, DEFB1, DEFB103A, DEFB4A
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| Human defensin gene copy number polymorphisms: comprehensive analysis of independent variation in alpha- and beta-defensin regions at 8p22-p23.
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| Linzmeier RM, Ganz T.
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| Genomics 86(4):423-30. 2005
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| 14 | DEFA1, DEFA3, DEFB4A
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| Extensive normal copy number variation of a beta-defensin antimicrobial-gene cluster.
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| Hollox EJ, Armour JA, Barber JC.
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| Am J Hum Genet 73(3):591-600. Epub 2003 Aug 12. 2003
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| 15 | DEFA1, ERCC6
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| A Rad26-Def1 complex coordinates repair and RNA pol II proteolysis in response to DNA damage.
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| Woudstra EC, Gilbert C, Fellows J, Jansen L, Brouwer J, Erdjument-Bromage H, Tempst P, Svejstrup JQ.
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| Nature 415(6874):929-33. 2002
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| 16 | DEFA1, DEFA3
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| Contribution of human alpha-defensin 1, 2, and 3 to the anti-HIV-1 activity of CD8 antiviral factor.
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| Zhang L, Yu W, He T, Yu J, Caffrey RE, Dalmasso EA, Fu S, Pham T, Mei J, Ho JJ, Zhang W, Lopez P, Ho DD.
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| Science 298(5595):995-1000. 2002
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| 17 | DEFA1, DEFB1
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| The human beta-defensin-1 and alpha-defensins are encoded by adjacent genes: two peptide families with differing disulfide topology share a common ancestry.
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| Liu L, Zhao C, Heng HH, Ganz T.
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| Genomics 43(3):316-20. 1997
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| 18 | DEFA1, DEFA5, DEFA6
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| Human enteric defensin genes : chromosomal map position and a model for possible evolutionary relationships.
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| Bevins CL, et al.
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| Genomics 31 : 95-106. 1996
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| 19 | DEFA1, DEFA3, DEFA@
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| The structure of neutrophil defensin genes.
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| Linzmeier R, et al.
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| FEBS Lett 321 : 267-273. 1993
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| 20 | DEFA1, DEFA@
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| Assignment of defensin gene(s) to human chromosome 8p23.
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| Sparkes RS, Kronenberg M, Heinzmann C, Daher KA, Klisak I, Ganz T, Mohandas T.
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| Genomics 5 : 240-244. 1989
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| 21 | DEFA1
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| A myeloid-related sequence that localizes to human chromosome 8q21.1-22.
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| Mars WM, et al.
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| Blood 71 : 1713-1719. 1988
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