Citations for
1ARVCF, DDX5, HNRNPH2, SRSF1
Nuclear ARVCF protein binds splicing factors and contributes to the regulation of alternative splicing.
Rappe U, Schlechter T, Aschoff M, Hotz-Wagenblatt A, Hofmann I.
J Biol Chem 289(18):12421-34. doi: 10.1074/jbc.M113.530717. Epub 2014 Mar 18. 2014
2DDX17, DDX5
RNA helicases DDX5 and DDX17 dynamically orchestrate transcription, miRNA, and splicing programs in cell differentiation.
Dardenne E, Polay Espinoza M, Fattet L, Germann S, Lambert MP, Neil H, Zonta E, Mortada H, Gratadou L, Deygas M, Chakrama FZ, Samaan S, Desmet FO, Tranchevent LC, Dutertre M, Rimokh R, Bourgeois CF, Auboeuf D.
Cell Rep 7(6):1900-13. doi: 10.1016/j.celrep.2014.05.010. Epub 2014 Jun 6. 2014
3DDX5, MAML1
DDX5 is a positive regulator of oncogenic NOTCH1 signaling in T cell acute lymphoblastic leukemia.
Lin S, Tian L, Shen H, Gu Y, Li JL, Chen Z, Sun X, You MJ, Wu L.
Oncogene 32(40):4845-53. doi: 10.1038/onc.2012.482. Epub 2012 Oct 29. 2013
4DDX17, DDX5, NFAT5
Dual role of the ddx5/ddx17 RNA helicases in the control of the pro-migratory NFAT5 transcription factor.
Germann S, Gratadou L, Zonta E, Dardenne E, Gaudineau B, Fougère M, Samaan S, Dutertre M, Jauliac S, Auboeuf D.
Oncogene 31(42):4536-49. doi: 10.1038/onc.2011.618. Epub 2012 Jan 23. 2012
5DDX5
RNA helicase DDX5 is a p53-independent target of ARF that participates in ribosome biogenesis.
Saporita AJ, Chang HC, Winkeler CL, Apicelli AJ, Kladney RD, Wang J, Townsend RR, Michel LS, Weber JD.
Cancer Res 71(21):6708-17. doi: 10.1158/0008-5472.CAN-11-1472. Epub 2011 Sep 21. 2011
6DDX1, DDX17, DDX20, DDX21, DDX25, DDX39, DDX3X, DDX42, DDX5, DDX54, DDX6
DEAD-box helicases: posttranslational regulation and function.
Gustafson EA, Wessel GM.
Biochem Biophys Res Commun 395(1):1-6. Epub 2010 Mar 3. Review. No abstract available. PMID: 20206133 2010
7DDX5
A DDX5 S480A polymorphism is associated with increased transcription of fibrogenic genes in hepatic stellate cells.
Guo J, Hong F, Loke J, Yea S, Lim CL, Lee U, Mann DA, Walsh MJ, Sninsky JJ, Friedman SL.
J Biol Chem 285(8):5428-37. Epub 2009 Dec 17.PMID: 20022962 2010
8CTCF, DDX5, SRA1
Mediation of CTCF transcriptional insulation by DEAD-box RNA-binding protein p68 and steroid receptor RNA activator SRA.
Yao H, Brick K, Evrard Y, Xiao T, Camerini-Otero RD, Felsenfeld G.
Genes Dev 24(22):2543-55. Epub 2010 Oct 21. 2010
9DDX5
SAGE analysis highlights the importance of p53csv, ddx5, mapkapk2 and ranbp2 to multiple myeloma tumorigenesis.
Felix RS, Colleoni GW, Caballero OL, Yamamoto M, Almeida MS, Andrade VC, Chauffaille Mde L, Silva WA Jr, Begnami MD, Soares FA, Simpson AJ, Zago MA, Vettore AL.
Cancer Lett 278(1):41-8. Epub 2009 Jan 25.PMID: 19171422 2009
10DDX5
Interaction between SARS-CoV helicase and a multifunctional cellular protein (Ddx5) revealed by yeast and mammalian cell two-hybrid systems.
Chen JY, Chen WN, Poon KM, Zheng BJ, Lin X, Wang YX, Wen YM.
Arch Virol 154(3):507-12. Epub 2009 Feb 18.PMID: 19224332 2009
11DDX17, DDX5
The DEAD-box protein p72 regulates ERalpha-/oestrogen-dependent transcription and cell growth, and is associated with improved survival in ERalpha-positive breast cancer.
Wortham NC, Ahamed E, Nicol SM, Thomas RS, Periyasamy M, Jiang J, Ochocka AM, Shousha S, Huson L, Bray SE, Coombes RC, Ali S, Fuller-Pace FV.
Oncogene 28(46):4053-64. doi: 10.1038/onc.2009.261. Epub 2009 Aug 31. 2009
12DDX5
The RNA helicase p68 is a novel androgen receptor coactivator involved in splicing and is overexpressed in prostate cancer.
Clark EL, Coulson A, Dalgliesh C, Rajan P, Nicol SM, Fleming S, Heer R, Gaughan L, Leung HY, Elliott DJ, Fuller-Pace FV, Robson CN.
Cancer Res 68(19):7938-46.PMID: 18829551 2008
13DDX5
A fluorescence in situ hybridization screen for E26 transformation-specific aberrations: identification of DDX5-ETV4 fusion protein in prostate cancer.
Han B, Mehra R, Dhanasekaran SM, Yu J, Menon A, Lonigro RJ, Wang X, Gong Y, Wang L, Shankar S, Laxman B, Shah RB, Varambally S, Palanisamy N, Tomlins SA, Kumar-Sinha C, Chinnaiyan AM.
Cancer Res 68(18):7629-37. 2008
14DDX5
A double tyrosine phosphorylation of P68 RNA helicase confers resistance to TRAIL-induced apoptosis.
Yang L, Lin C, Sun SY, Zhao S, Liu ZR.
Oncogene 26(41):6082-92. Epub 2007 Mar 26.PMID: 17384675 2007
15DDX5, HDAC1
SUMO modification of the DEAD box protein p68 modulates its transcriptional activity and promotes its interaction with HDAC1.
Jacobs AM, Nicol SM, Hislop RG, Jaffray EG, Hay RT, Fuller-Pace FV.
Oncogene 26(40):5866-76. Epub 2007 Mar 19.PMID: 17369852 2007
16DDX17, DDX5
Involvement of RNA helicases p68 and p72 in colon cancer.
Shin S, Rossow KL, Grande JP, Janknecht R.
Cancer Res 67(16):7572-8. 2007
17DDX5
P68 RNA helicase mediates PDGF-induced epithelial mesenchymal transition by displacing Axin from beta-catenin.
Yang L, Lin C, Liu ZR.
Cell 127(1):139-55. 2006
18DDX5
Identification of two gene variants associated with risk of advanced fibrosis in patients with chronic hepatitis C.
Huang H, Shiffman ML, Cheung RC, Layden TJ, Friedman S, Abar OT, Yee L, Chokkalingam AP, Schrodi SJ, Chan J, Catanese JJ, Leong DU, Ross D, Hu X, Monto A, McAllister LB, Broder S, White T, Sninsky JJ, Wright TL.
Gastroenterology 130(6):1679-87. Epub 2006 Mar 6. 2006
19DDX5, TLK1
Identification of the human DEAD-box protein p68 as a substrate of Tlk1.
Kodym R, Henockl C, Furweger C.
Biochem Biophys Res Commun 333(2):411-7. 2005
20DDX5
The DEAD box protein p68: a novel transcriptional coactivator of the p53 tumour suppressor.
Bates GJ, Nicol SM, Wilson BJ, Jacobs AM, Bourdon JC, Wardrop J, Gregory DJ, Lane DP, Perkins ND, Fuller-Pace FV.
EMBO J 24(3):543-53. Epub 2005 Jan 20. 2005
21AP1S1, ATP6V1D, BM22, CASP8AP2, CDC16, CDC27, CENPE, CLDN16, CMTM4, CYTH3, DDX5, DHX8, EIF3A, EIF3H, EIF4A3, GALNT5, ITPR1, KIF11, KPNB1, LSM6, MFAP1, NCAPD3, NCAPG2, RBM19, RRM2, SART1, SNRPA1, SNRPB, SNW1, SPC25, VCP, ZDHHC5
An endoribonuclease-prepared siRNA screen in human cells identifies genes essential for cell division.
Kittler R, Putz G, Pelletier L, Poser I, Heninger AK, Drechsel D, Fischer S, Konstantinova I, Habermann B, Grabner H, Yaspo ML, Himmelbauer H, Korn B, Neugebauer K, Pisabarro MT, Buchholz F.
Nature 432(7020):1036-40. 2004
22DDX5
Structure and expression of the human p68 RNA helicase gene.
Rossler OG, Hloch P, Schutz N, Weitzenegger T, Stahl H.
Nucleic Acids Res 28(4):932-9. 2000
23AOC3P,ATP6V0A1,BRCA1,DDX5,ETV4,EZH1,FLT4R,GSD1A,HMG17P1,HSD17B1,NRXN3,RPL27,TUBG1
Construction of a transcription map surrounding the BRCA1 locus of human chromosome 17.
Brody LC, et al.
Genomics 25 : 238-247. 1995
24DDX5
Chromosome mapping of the human gene encoding the 68-kDa nuclear antigen (p68) by using the polymerase chain reaction.
Iggo R, Gough A, Xu W, Lane DP, Spurr NK.
Proc Natl Acad Sci U S A 86 : 6211-6214. 1989