1 | DDX1
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| DDX1 vesicles control calcium-dependent mitochondrial activity in mouse embryos.
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| Wang Y, Yasmin L, Li L, Gao P, Xu X, Sun X, Godbout R.
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| Nat Commun. Jul 1;13(1):3794. doi: 10.1038/s41467-022-31497-9. 2022
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2 | DDX1
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| DEAD box 1 (DDX1) protein binds to and protects cytoplasmic stress response mRNAs in cells exposed to oxidative stress
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| Li L, Garg M, Wang Y, Wang W, Godbout R.
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| J Biol Chem. Aug;298(8):102180. doi: 10.1016/j.jbc.2022.102180. Epub 2022 Jun 23. 2022
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3 | DDX1, GLE1
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| Nucleocytoplasmic shuttling of Gle1 impacts DDX1 at transcription termination sites
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| Sharma M, Wente SR.
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| Mol Biol Cell. Oct 1;31(21):2398-2408. doi: 10.1091/mbc.E20-03-0215. Epub 2020 Aug 5. 2020
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4 | ATXN2, ATXN2L, DDX1, FAM98A, NUFIP2
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| FAM98A is localized to stress granules and associates with multiple stress granule-localized proteins.
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| Ozeki K, Sugiyama M, Akter KA, Nishiwaki K, Asano-Inami E, Senga T.
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| Mol Cell Biochem. Jan;451(1-2):107-115. doi: 10.1007/s11010-018-3397-6. Epub 2018 Jul 10. 2019
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5 | DDX1
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| Cytoplasmic aggregation of DDX1 in developing embryos: Early embryonic lethality associated with Ddx1 knockout.
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| Hildebrandt MR, Wang Y, Li L, Yasmin L, Glubrecht DD, Godbout R.
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| Dev Biol. Nov 15;455(2):420-433. doi: 10.1016/j.ydbio.2019.07.014. Epub 2019 Jul 19. 2019
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6 | DDX1, LGR5
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| DEAD box protein DDX1 promotes colorectal tumorigenesis through transcriptional activation of the LGR5 gene
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| Tanaka K, Ikeda N, Miyashita K, Nuriya H, Hara T.
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| Cancer Sci. Aug;109(8):2479-2489. doi: 10.1111/cas.13661. Epub 2018 Jul 17. 2018
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7 | DDX1
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| DDX1 regulates alternative splicing and insulin secretion in pancreatic β cells.
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| Zhong W, Li Z, Zhou M, Xu T, Wang Y.
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| Biochem Biophys Res Commun. Jun 7;500(3):751-757. doi: 10.1016/j.bbrc.2018.04.147. Epub 2018 Apr 23 2018
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8 | DDX1, RIF1
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| Role for RIF1-interacting partner DDX1 in BLM recruitment to DNA double-strand breaks.
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| Li L, Poon HY, Hildebrandt MR, Monckton EA, Germain DR, Fahlman RP, Godbout R.
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| DNA Repair (Amst). Jul;55:47-63. doi: 10.1016/j.dnarep.2017.05.001. Epub 2017 May 13. 2017
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9 | DDX1
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| DEAD Box 1 Facilitates Removal of RNA and Homologous Recombination at DNA Double-Strand Breaks
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| Li L, Germain DR, Poon HY, Hildebrandt MR, Monckton EA, McDonald D, Hendzel MJ, Godbout R.
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| Mol Cell Biol. Oct 28;36(22):2794-2810. doi: 10.1128/MCB.00415-16 2016
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10 | DDX1
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| Synergistic effects of ATP and RNA binding to human DEAD-box protein DDX1.
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| Kellner JN, Reinstein J, Meinhart A.
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| Nucleic Acids Res. Mar 11;43(5):2813-28. doi: 10.1093/nar/gkv106. Epub 2015 Feb 17 2015
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11 | DDX1, KHSRP
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| DEAD box protein DDX1 regulates cytoplasmic localization of KSRP.
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| Chou CF, Lin WJ, Lin CC, Luber CA, Godbout R, Mann M, Chen CY.
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| PLoS One 8(9):e73752. doi: 10.1371/journal.pone.0073752.
2013
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12 | DDX1, DDX3X
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| Distinct DDX DEAD-box RNA helicases cooperate to modulate the HIV-1 Rev function.
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| Yasuda-Inoue M, Kuroki M, Ariumi Y.
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| Biochem Biophys Res Commun 434(4):803-8. doi: 10.1016/j.bbrc.2013.04.016. Epub 2013 Apr 19.
2013
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13 | DDX1, DHX3X, DHX9
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| DExD/H-box RNA helicases as mediators of anti-viral innate immunity and essential host factors for viral replication.
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| Fullam A, Schröder M.
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| Biochim Biophys Acta 1829(8):854-65. doi: 10.1016/j.bbagrm.2013.03.012. Epub 2013 Apr 6. Review.
2013
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14 | DDX1
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| DDX1 is an RNA-dependent ATPase involved in HIV-1 Rev function and virus replication.
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| Edgcomb SP, Carmel AB, Naji S, Ambrus-Aikelin G, Reyes JR, Saphire AC, Gerace L, Williamson JR.
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| J Mol Biol 415(1):61-74. doi: 10.1016/j.jmb.2011.10.032. Epub 2011 Oct 25.
2012
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15 | DDX1
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| Single-molecule studies reveal that DEAD box protein DDX1 promotes oligomerization of HIV-1 Rev on the Rev response element.
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| Robertson-Anderson RM, Wang J, Edgcomb SP, Carmel AB, Williamson JR, Millar DP.
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| J Mol Biol 410(5):959-71. doi: 10.1016/j.jmb.2011.04.026.
2011
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16 | DDX1, DDX21, DHX36
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| DDX1, DDX21, and DHX36 helicases form a complex with the adaptor molecule TRIF to sense dsRNA in dendritic cells.
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| Zhang Z, Kim T, Bao M, Facchinetti V, Jung SY, Ghaffari AA, Qin J, Cheng G, Liu YJ.
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| Immunity 34(6):866-78. doi: 10.1016/j.immuni.2011.03.027.
2011
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17 | DDX1
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| Dead-box or black-box: is DDX1 a potential biomarker in breast cancer?
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| Balko JM, Arteaga CL.
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| Breast Cancer Res Treat 127(1):65-7. doi: 10.1007/s10549-010-1105-7. Epub 2010 Aug 8. No abstract available.
2011
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18 | DDX1, DDX17, DDX20, DDX21, DDX25, DDX39, DDX3X, DDX42, DDX5, DDX54, DDX6
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| DEAD-box helicases: posttranslational regulation and function.
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| Gustafson EA, Wessel GM.
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| Biochem Biophys Res Commun 395(1):1-6. Epub 2010 Mar 3. Review. No abstract available. PMID: 20206133 2010
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19 | DDX1
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| DDX1 is required for testicular tumorigenesis, partially through the transcriptional activation of 12p stem cell genes.
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| Tanaka K, Okamoto S, Ishikawa Y, Tamura H, Hara T.
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| Oncogene 28(21):2142-51. Epub 2009 Apr 27.
2009
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20 | DDX1, NBAS
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| Relationship of DDX1 and NAG gene amplification/overexpression to the prognosis of patients with MYCN-amplified neuroblastoma.
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| Kaneko S, Ohira M, Nakamura Y, Isogai E, Nakagawara A, Kaneko M.
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| J Cancer Res Clin Oncol 133(3):185-92. Epub 2006 Oct 7. 2007
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21 | DDX1, MYCN
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| Concomitant DDX1 and MYCN gain in neuroblastoma.
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| Defferrari R, Tonini GP, Conte M, Papio F, Sementa AR, Valent A, Schena F, Perri P, Mazzocco K.
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| Cancer Lett 256(1):56-63. Epub 2007 Jul 3. 2007
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22 | DDX1, MYCN
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| Relational mapping of MYCN and DDXI in band 2p24 and analysis of amplicon arrays in double minute chromosomes and homogeneously staining regions by use of free chromatin FISH.
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| Pandita A, Godbout R, Zielenska M, Thorner P, Bayani J, Squire JA.
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| Genes Chromosomes Cancer 20(3):243-52. 1997
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23 | DDX1, MYCN, NBL
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| Amplification of a DEAD box gene (DDXI) with the MYCN gene in neuroblastomas as a result of cosegregation of sequences flanking the MYCN locus.
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| Noguchi T, et al.
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| Genes Chromosomes Cancer 15 : 129-133. 1996
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24 | DDX1, MYCN, NBL
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| The DDXI gene maps within 400 kbp 5' to MYCN and is frequently coamplified in human neuroblastoma.
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| Amler LC, et al.
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| Genes Chromosomes Cancer 15 : 134-137. 1996
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25 | DDX1, MYCN
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| Physical mapping of the DDX1 gene to 340 kb 5' of MYCN.
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| Kuroba H, et al.
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| Oncogene 13 : 1561-1565. 1996
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26 | DDX1, MYCN, NBL
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| Co-amplification of MYCN and a DEAD box gene (DDX1) in primary neuroblastoma.
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| Squire JA, et al.
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| Oncogene 10 : 1417-1422. 1995
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27 | DDX1
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| Amplification of a DEAD box protein gene in retinoblastoma cell lines.
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| Godbout R, et al.
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| Proc Natl Acad Sci U S A 90 : 7578-7582. 1993
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28 | DDX1, DDX39B, DDX6, DHX16, EIF4A2, RFC1
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| D-E-A-D protein family of putative RNA helicases.
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| Schmid SR, et al.
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| Mol Microbiol 6 : 283-292. 1992
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29 | DDX1, DDX39B, DHX16, EIF4A2, RFC1
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| Birth of the D-E-A-D box.
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| Linder P, et al.
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| Nature 337 : 121-122. 1989
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