Citations for
1BCLAF1, DDIT4, FAM126B, FKBP1A, YWHAQ
Peripheral blood transcriptome identifies high-risk benign and malignant breast lesions
Hou H, Lyu Y, Jiang J, Wang M, Zhang R, Liew CC, Wang B, Cheng C.
PLoS One. Jun 4;15(6):e0233713. doi: 10.1371/journal.pone.0233713. 2020
2DDIT4, TAL1
The SCL/TAL1 Transcription Factor Represses the Stress Protein DDiT4/REDD1 in Human Hematopoietic Stem/Progenitor Cells.
Benyoucef A, Calvo J, Renou L, Arcangeli ML, van den Heuvel A, Amsellem S, Mehrpour M, Larghero J, Soler E, Naguibneva I, Pflumio F.
Stem Cells 33(7):2268-79. doi: 10.1002/stem.2028. Epub 2015 May 25. 2015
3DDIT4
REDD1 protects osteoblast cells from gamma radiation-induced premature senescence.
Li XH, Ha CT, Fu D, Xiao M.
PLoS One 7(5):e36604. doi: 10.1371/journal.pone.0036604. Epub 2012 May 18. 2012
4DDIT4, MTOR
Attenuation of TORC1 signaling delays replicative and oncogenic RAS-induced senescence.
Kolesnichenko M, Hong L, Liao R, Vogt PK, Sun P.
Cell Cycle 11(12):2391-401. doi: 10.4161/cc.20683. Epub 2012 Jun 15. 2012
5DDIT4, EIF2AK3, EIF2S1
Induction of REDD1 gene expression in the liver in response to endoplasmic reticulum stress is mediated through a PERK, eIF2α phosphorylation, ATF4-dependent cascade.
Kimball SR, Jefferson LS.
Biochem Biophys Res Commun 427(3):485-9. doi: 10.1016/j.bbrc.2012.09.074. Epub 2012 Sep 20. 2012
6DDIT4
RTP801/REDD1 regulates the timing of cortical neurogenesis and neuron migration.
Malagelada C, López-Toledano MA, Willett RT, Jin ZH, Shelanski ML, Greene LA.
J Neurosci 31(9):3186-96. 2011
7DDIT4
Redd1 inhibits the invasiveness of non-small cell lung cancer cells.
Jin HO, Seo SK, Woo SH, Kim YS, Hong SE, Yi JY, Noh WC, Kim EK, Lee JK, Hong SI, Choe TB, Park IC.
Biochem Biophys Res Commun 407(3):507-11. Epub 2011 Mar 23. 2011
8DDIT4, MTOR, TXNIP
TXNIP potentiates Redd1-induced mTOR suppression through stabilization of Redd1.
Jin HO, Seo SK, Kim YS, Woo SH, Lee KH, Yi JY, Lee SJ, Choe TB, Lee JH, An S, Hong SI, Park IC.
Oncogene 30(35):3792-801. doi: 10.1038/onc.2011.102. Epub 2011 Apr 4. 2011
9DDIT4
Feedback control of p53 translation by REDD1 and mTORC1 limits the p53-dependent DNA damage response.
Vadysirisack DD, Baenke F, Ory B, Lei K, Ellisen LW.
Mol Cell Biol 31(21):4356-65. doi: 10.1128/MCB.05541-11. Epub 2011 Sep 6. 2011
10DDIT4
Glucocorticoid elevation of dexamethasone-induced gene 2 (Dig2/RTP801/REDD1) protein mediates autophagy in lymphocytes.
Molitoris JK, McColl KS, Swerdlow S, Matsuyama M, Lam M, Finkel TH, Matsuyama S, Distelhorst CW.
J Biol Chem 286(34):30181-9. doi: 10.1074/jbc.M111.245423. Epub 2011 Jul 6. Erratum in: J Biol Chem. 2011 Nov 11;286(45):39673. 2011
11DDIT4, MTOR
Cell-type-dependent regulation of mTORC1 by REDD1 and the tumor suppressors TSC1/TSC2 and LKB1 in response to hypoxia.
Wolff NC, Vega-Rubin-de-Celis S, Xie XJ, Castrillon DH, Kabbani W, Brugarolas J.
Mol Cell Biol 31(9):1870-84. doi: 10.1128/MCB.01393-10. Epub 2011 Mar 7. 2011
12DDIT4, HIF1A
Insulin induces REDD1 expression through hypoxia-inducible factor 1 activation in adipocytes.
Regazzetti C, Bost F, Le Marchand-Brustel Y, Tanti JF, Giorgetti-Peraldi S.
J Biol Chem 285(8):5157-64. Epub 2009 Dec 8. 2010
13DDIT4, MTOR
Structural analysis and functional implications of the negative mTORC1 regulator REDD1.
Vega-Rubin-de-Celis S, Abdallah Z, Kinch L, Grishin NV, Brugarolas J, Zhang X.
Biochemistry 49(11):2491-501. doi: 10.1021/bi902135e. 2010
14ATF4, DDIT4
ATF4 is necessary and sufficient for ER stress-induced upregulation of REDD1 expression.
Whitney ML, Jefferson LS, Kimball SR.
Biochem Biophys Res Commun 379(2):451-5. Epub 2008 Dec 27. 2009
15DDIT4
REDD1, an inhibitor of mTOR signalling, is regulated by the CUL4A-DDB1 ubiquitin ligase.
Katiyar S, Liu E, Knutzen CA, Lang ES, Lombardo CR, Sankar S, Toth JI, Petroski MD, Ronai Z, Chiang GG.
EMBO Rep 10(8):866-72. Epub 2009 Jun 26. 2009
16DDIT4
Inhibition of fatty-acid synthase induces caspase-8-mediated tumor cell apoptosis by up-regulating DDIT4.
Knowles LM, Yang C, Osterman A, Smith JW.
J Biol Chem 283(46):31378-84. Epub 2008 Sep 16. 2008
17DDIT4
RTP801 is elevated in Parkinson brain substantia nigral neurons and mediates death in cellular models of Parkinson's disease by a mechanism involving mammalian target of rapamycin inactivation.
Malagelada C, Ryu EJ, Biswas SC, Jackson-Lewis V, Greene LA.
J Neurosci 26(39):9996-10005. 2006
18DDIT4, DDIT4L
The stress-inducted proteins RTP801 and RTP801L are negative regulators of the mammalian target of rapamycin pathway.
Corradetti MN, Inoki K, Guan KL.
J Biol Chem 280(11):9769-72. Epub 2005 Jan 4. 2005
19DDIT4
REDD1 integrates hypoxia-mediated survival signaling downstream of phosphatidylinositol 3-kinase.
Schwarzer R, Tondera D, Arnold W, Giese K, Klippel A, Kaufmann J.
Oncogene 24(7):1138-49. 2005
20DDIT4
Identification of amyloid beta-peptide responsive genes by cDNA microarray technology: involvement of RTP801 in amyloid beta-peptide toxicity.
Kim JR, Lee SR, Chung HJ, Kim S, Baek SH, Kim JH, Kim YS.
Exp Mol Med 35(5):403-11. 2003
21DDIT4
Identification of a novel hypoxia-inducible factor 1-responsive gene, RTP801, involved in apoptosis.
Shoshani T, Faerman A, Mett I, Zelin E, Tenne T, Gorodin S, Moshel Y,Elbaz S, Budanov A, Chajut A, Kalinski H, Kamer I, Rozen A, Mor O, Keshet E,Leshkowitz D, Einat P, Skaliter R, Feinstein E.
Mol Cell Biol 22(7):2283-93. 2002