Citations for
1DCTN1, SLK
Ste20-like protein kinase SLK (LOSK) regulates microtubule organization by targeting dynactin to the centrosome.
Zhapparova ON, Fokin AI, Vorobyeva NE, Bryantseva SA, Nadezhdina ES.
Mol Biol Cell 24(20):3205-14. doi: 10.1091/mbc.E13-03-0137. Epub 2013 Aug 28. 2013
2AURKA, DCTN1
Aurora A is involved in central spindle assembly through phosphorylation of Ser 19 in P150Glued.
Reboutier D, Troadec MB, Cremet JY, Chauvin L, Guen V, Salaun P, Prigent C.
J Cell Biol 201(1):65-79. doi: 10.1083/jcb.201210060. Erratum in: J Cell Biol. 2013 Apr 29;201(3):487. 2013
3DCTN1, MREG, RILP
Melanoregulin regulates retrograde melanosome transport through interaction with the RILP-p150Glued complex in melanocytes.
Ohbayashi N, Maruta Y, Ishida M, Fukuda M.
J Cell Sci 125(Pt 6):1508-18. Epub 2012 Jan 24. 2012
4BICD2, DCTN1, PAFAH1B1
BICD2, dynactin, and LIS1 cooperate in regulating dynein recruitment to cellular structures.
Splinter D, Razafsky DS, Schlager MA, Serra-Marques A, Grigoriev I, Demmers J, Keijzer N, Jiang K, Poser I, Hyman AA, Hoogenraad CC, King SJ, Akhmanova A.
Mol Biol Cell 23(21):4226-41. doi: 10.1091/mbc.E12-03-0210. Epub 2012 Sep 5. 2012
5DCTN1, TRAPPC9
TRAPPC9 mediates the interaction between p150 and COPII vesicles at the target membrane.
Zong M, Satoh A, Yu MK, Siu KY, Ng WY, Chan HC, Tanner JA, Yu S.
PLoS One 7(1):e29995. doi: 10.1371/journal.pone.0029995. Epub 2012 Jan 18. 2012
6DCTN1
Cooperative effect of p150Glued and microtubule stabilization to suppress excitotoxicity-induced axon degeneration.
Fujiwara T, Morimoto K.
Biochem Biophys Res Commun 424(1):82-8. doi: 10.1016/j.bbrc.2012.06.071. Epub 2012 Jun 21. 2012
7DCTN1, NDE1
Intrinsic disorder in dynein intermediate chain modulates its interactions with NudE and dynactin.
Nyarko A, Song Y, Barbar E.
J Biol Chem 287(30):24884-93. doi: 10.1074/jbc.M112.376038. Epub 2012 Jun 5. 2012
8DCTN1, GPSM2, NUMA1
Asymmetric cell divisions promote Notch-dependent epidermal differentiation.
Williams SE, Beronja S, Pasolli HA, Fuchs E.
Nature 470(7334):353-8. 2011
9DCTN1, HTT, NUMA1
Mitotic spindle: focus on the function of huntingtin.
Godin JD, Humbert S.
Int J Biochem Cell Biol 43(6):852-6. Epub 2011 Mar 23. Review. 2011
10DCTN1, PERS
DCTN1 mutations are implicated in multiple neurodegenerative disorders.
Uribe V.
Clin Genet 77(1):32-4. No abstract available. PMID: 20101786 2010
11DCTN1, PLK1
Polo-like kinase 1 phosphorylation of p150Glued facilitates nuclear envelope breakdown during prophase.
Li H, Liu XS, Yang X, Song B, Wang Y, Liu X.
Proc Natl Acad Sci U S A 107(33):14633-8. Epub 2010 Aug 2.PMID: 20679239 2010
12DCTN1, PARD6A
Par6 alpha interacts with the dynactin subunit p150 Glued and is a critical regulator of centrosomal protein recruitment.
Kodani A, Tonthat V, Wu B, Sütterlin C.
Mol Biol Cell 21(19):3376-85. doi: 10.1091/mbc.E10-05-0430. Epub 2010 Aug 18. 2010
13BICD2, DCTN1, GOPC, RAB6A
Biophysical analysis of the interaction of Rab6a GTPase with its effector domains.
Bergbrede T, Chuky N, Schoebel S, Blankenfeldt W, Geyer M, Fuchs E, Goody RS, Barr F, Alexandrov K.
J Biol Chem 284(5):2628-35. Epub 2008 Nov 19.PMID: 19019823 2009
14DCTN1, PERS
DCTN1 mutations in Perry syndrome.
Farrer MJ, Hulihan MM, Kachergus JM, Dächsel JC, Stoessl AJ, Grantier LL, Calne S, Calne DB, Lechevalier B, Chapon F, Tsuboi Y, Yamada T, Gutmann L, Elibol B, Bhatia KP, Wider C, Vilariño-Güell C, Ross OA, Brown LA, Castanedes-Casey M, Dickson DW, Wszolek ZK.
Nat Genet 41(2):163-5. Epub 2009 Jan 11. 2009
15DCTN1
Neurodegeneration mutations in dynactin impair dynein-dependent nuclear migration.
Moore JK, Sept D, Cooper JA.
Proc Natl Acad Sci U S A 106(13):5147-52. Epub 2009 Mar 11. 2009
16DCTN1, SNX6
The retromer component SNX6 interacts with dynactin p150(Glued) and mediates endosome-to-TGN transport.
Hong Z, Yang Y, Zhang C, Niu Y, Li K, Zhao X, Liu JJ.
Cell Res 19(12):1334-49. doi: 10.1038/cr.2009.130. Epub 2009 Nov 24. 2009
17DCTN1, LMND
Lysosomal proliferation and distal degeneration in motor neurons expressing the G59S mutation in the p150Glued subunit of dynactin.
Chevalier-Larsen ES, Wallace KE, Pennise CR, Holzbaur EL.
Hum Mol Genet 17(13):1946-55. Epub 2008 Mar 25. 2008
18ACTR1A, DCTN1, DCTN2
Dynactin is essential for growth cone advance.
Abe TK, Honda T, Takei K, Mikoshiba K, Hoffman-Kim D, Jay DG, Kuwano R.
Biochem Biophys Res Commun 372(3):418-22. Epub 2008 May 12. 2008
19DCTN1, HAP1, HTT, REST, RILP
Huntingtin regulates RE1-silencing transcription factor/neuron-restrictive silencer factor (REST/NRSF) nuclear trafficking indirectly through a complex with REST/NRSF-interacting LIM domain protein (RILP) and dynactin p150 Glued.
Shimojo M.
J Biol Chem 283(50):34880-6. Epub 2008 Oct 15. 2008
20DCTN1,FBXL5
FBXL5 interacts with p150Glued and regulates its ubiquitination.
Zhang N, Liu J, Ding X, Aikhionbare F, Jin C, Yao X.
Biochem Biophys Res Commun 359(1):34-9. Epub 2007 May 21. 2007
21DCTN1
Microtubule plus-end loading of p150(Glued) is mediated by EB1 and CLIP-170 but is not required for intracellular membrane traffic in mammalian cells.
Watson P, Stephens DJ.
J Cell Sci 119(Pt 13):2758-67. Epub 2006 Jun 13. 2006
22DCTN1
A motor neuron disease-associated mutation in p150Glued perturbs dynactin function and induces protein aggregation.
Levy JR, Sumner CJ, Caviston JP, Tokito MK, Ranganathan S, Ligon LA, Wallace KE, LaMonte BH, Harmison GG, Puls I, Fischbeck KH, Holzbaur EL.
J Cell Biol 172(5):733-45. 2006
23BDNF, HTT, HAP1, DCTN1
Huntingtin controls neurotrophic support and survival of neurons by enhancing BDNF vesicular transport along microtubules.
Gauthier LR, Charrin BC, Borrell-Pages M, Dompierre JP, Rangone H, Cordelieres FP, De Mey J, MacDonald ME, Lessmann V, Humbert S, Saudou F.
Cell 118(1):127-38. 2004
24DCTN1, LMND
Mutant dynactin in motor neuron disease.
Puls I, Jonnakuty C, LaMonte BH, Holzbaur EL, Tokito M, Mann E, Floeter MK, Bidus K, Drayna D, Oh SJ, Brown RH Jr, Ludlow CL, Fischbeck KH.
Nat Genet 33(4):455-6. 2003
25CCT4, DCTN1, DOK1, DUSP11, EGR4, EXOC6B, PARK3, SEMA4F, SMYD5, SPR, STAMBP, TIA1, ZNF638
Refinement of the PARK3 locus on chromosome 2p13 and the analysis of 14 candidate genes.
West AB, Zimprich A, Lockhart PJ, Farrer M, Singleton A, Holtom B, Lincoln S, Hofer A, Hill L, Muller-Myhsok B, Wszolek ZK, Hardy J, Gasser T.
Eur J Hum Genet 9(9):659-66. 2001
26DCTN1, SLC4A5
Genomic organization of the DCTN1-SLC4A5 locus encoding both NBC4 and p150(Glued).
Pushkin A, Abuladze N, Newman D, Tatishchev S, Kurtz I.
Cytogenet Cell Genet 95(3-4):163-8. 2001
27DCTN1
Human DCTN1 : genomic structure and evaluation as a candidate for Alstršm syndrome.
Collin GB, et al.
Genomics 53 : 359-364. 1998
28DCTN1
The genomic structure of DCTN1, a candidate gene for limb-girdle muscular dystrophy (LGMD2B).
Tokito MK, Holzbaur EL.
Biochim Biophys Acta 1442 : 432-436. 1998
29DCTN1, LGMD2B
Integrated radiation hybrid map of human chromosome 2p13: possible involvement of dynactin in neuromuscular diseases.
Korthaus D, Wedemeyer N, Lengeling A, Ronsiek M, Jockusch H, Schmitt-John T.
Genomics 43(2):242-4. 1997
30DCTN1
Localization of the DCTN1 gene encoding p150glued to human chromosome 2p13 by fluorescence in situ hybridization.
Holzbaur ELF, et al.
Genomics 31 : 398-399. 1996
31DCTN1
Functionally distinct isoforms of dynactin are expressed in human neurons.
Tokito MK, et al.
Mol Biol Cell 7 : 1167-1180. 1996
32DCTN1, DCTN2, DNAH1, DNAH12, DNAH13, DNAH2, DNAH6, DNAH8, DYNC1H1, DYNC2H1, DYNC1I1, DYNC1I2, DYNC1LI2, DNAH9
Multiple mouse chromosomal loci for dynein-based motility.
Vaughan KT, Mikami A, Paschal BM, Holzbaur EL, Hughes SM, Echeverri CJ, Moore KJ, Gilbert DJ, Copeland NG, Jenkins NA, Vallee RB.
Genomics 36(1):29-38. 1996
33DCTN1
The p150glued component of the dynactin complex binds to both microtubules and the actin-related protein centractin (Arp-1).
Waterman-Storer CM, et al.
Proc Natl Acad Sci U S A 92 : 1634-1638. 1995
34DCTN1
Dynactin, a conserved, ubiquitously expressed component of an activator of vesicle motility mediated by cytoplasmic dynein.
Gill SR, et al.
J Cell Biol 115 : 1639-1650. 1991