Citations for
1DCN, ITGB1, WNT7A
Integrin signalling regulates the expansion of neuroepithelial progenitors and neurogenesis via Wnt7a and Decorin.
Long K, Moss L, Laursen L, Boulter L, ffrench-Constant C.
Nat Commun 7:10354. doi: 10.1038/ncomms10354. 2016
2BGN, DCN
The small leucine-rich proteoglycan BGN accumulates in CADASIL and binds to NOTCH3.
Zhang X, Lee SJ, Young MF, Wang MM.
Transl Stroke Res 6(2):148-55. doi: 10.1007/s12975-014-0379-1. Epub 2015 Jan 13. 2015
3BGN, DCN
The tendon injury response is influenced by decorin and biglycan.
Dunkman AA, Buckley MR, Mienaltowski MJ, Adams SM, Thomas SJ, Satchell L, Kumar A, Pathmanathan L, Beason DP, Iozzo RV, Birk DE, Soslowsky LJ.
Ann Biomed Eng 42(3):619-30. doi: 10.1007/s10439-013-0915-2. Epub 2013 Sep 27. 2014
4DCN, VIM
The dermatan sulfate proteoglycan decorin modulates α2β1 integrin and the vimentin intermediate filament system during collagen synthesis.
Jungmann O, Nikolovska K, Stock C, Schulz JN, Eckes B, Riethmüller C, Owens RT, Iozzo RV, Seidler DG.
PLoS One 7(12):e50809. doi: 10.1371/journal.pone.0050809. Epub 2012 Dec 3. 2012
5DCN, SPARC, SPRY1, TSKU
Stromal expression of decorin, Semaphorin6D, SPARC, Sprouty1 and Tsukushi in developing prostate and decreased levels of decorin in prostate cancer.
Henke A, Grace OC, Ashley GR, Stewart GD, Riddick AC, Yeun H, O'Donnell M, Anderson RA, Thomson AA.
PLoS One 7(8):e42516. doi: 10.1371/journal.pone.0042516. Epub 2012 Aug 3. 2012
6CTGF, DCN
Decorin interacts with CTGF/CCN2 through LRR12 inhibiting its biological activity.
Vial C, Gutierrez J, Santander C, Cabrera D, Brandan E.
J Biol Chem. 2011
7CTGF, DCN
Decorin interacts with connective tissue growth factor (CTGF)/CCN2 by LRR12 inhibiting its biological activity.
Vial C, Gutiérrez J, Santander C, Cabrera D, Brandan E.
J Biol Chem 286(27):24242-52. Epub 2011 Mar 23. 2011
8BMP1, DCN
Decorin is processed by three isoforms of bone morphogenetic protein-1 (BMP1).
von Marschall Z, Fisher LW.
Biochem Biophys Res Commun 391(3):1374-8. Epub 2009 Dec 22. 2010
9ATCS, CHST14, DCN
Loss-of-function mutations of CHST14 in a new type of Ehlers-Danlos syndrome.
Miyake N, Kosho T, Mizumoto S, Furuichi T, Hatamochi A, Nagashima Y, Arai E, Takahashi K, Kawamura R, Wakui K, Takahashi J, Kato H, Yasui H, Ishida T, Ohashi H, Nishimura G, Shiina M, Saitsu H, Tsurusaki Y, Doi H, Fukushima Y, Ikegawa S, Yamada S, Sugahara K, Matsumoto N.
Hum Mutat 31(8):966-74.PMID: 20533528 2010
10DCN
Decorin accumulation contributes to the stromal opacities found in congenital stromal corneal dystrophy.
Bredrup C, Stang E, Bruland O, Palka BP, Young RD, Haavik J, Knappskog PM, Rødahl E.
Invest Ophthalmol Vis Sci. 51(11):5578-82. 2010
11BGN, DCN
Genetic evidence for the coordinated regulation of collagen fibrillogenesis in the cornea by decorin and biglycan.
Zhang G, Chen S, Goldoni S, Calder BW, Simpson HC, Owens RT, McQuillan DJ, Young MF, Iozzo RV, Birk DE.
J Biol Chem 284(13):8888-97. Epub 2009 Jan 9. 2009
12BGN, DCN
Genetic evidence for key roles of decorin and biglycan in dentin mineralization.
Haruyama N, Sreenath TL, Suzuki S, Yao X, Wang Z, Wang Y, Honeycutt C, Iozzo RV, Young MF, Kulkarni AB.
Matrix Biol 28(3):129-36. Epub 2009 Feb 12. 2009
13DCN
Decorin promotes robust axon growth on inhibitory CSPGs and myelin via a direct effect on neurons.
Minor K, Tang X, Kahrilas G, Archibald SJ, Davies JE, Davies SJ.
Neurobiol Dis 32(1):88-95. Epub 2008 Jun 26. 2008
14DCN, NR1H4
Upregulation of decorin by FXR in vascular smooth muscle cells.
He F, Zhang Q, Kuruba R, Gao X, Li J, Li Y, Gong W, Jiang Y, Xie W, Li S.
Biochem Biophys Res Commun 372(4):746-51. Epub 2008 Jun 2. 2008
15DCN
Differential expression of decorin by human malignant and benign vascular tumors.
Salomäki HH, Sainio AO, Söderström M, Pakkanen S, Laine J, Järveläinen HT.
J Histochem Cytochem 56(7):639-46. Epub 2008 Apr 14. 2008
16DCN
Decorin derived antiangiogenic peptide LRR5 inhibits endothelial cell migration by interfering with VEGF-stimulated NO release.
Fan H, Sulochana KN, Chong YS, Ge R.
Int J Biochem Cell Biol 40(10):2120-8. Epub 2008 Feb 17. 2008
17DCN,DIO1,DIO2
Gene expression profiles reveal that DCN, DIO1, and DIO2 are underexpressed in benign and malignant thyroid tumors.
Arnaldi LA, Borra RC, Maciel RM, Cerutti JM.
Thyroid 15(3):210-21. 2005
18CSCD, DCN
Congenital stromal dystrophy of the cornea caused by a mutation in the decorin gene.
Bredrup C, Knappskog PM, Majewski J, Rødahl E, Boman H.
Invest Ophthalmol Vis Sci 46(2):420-6. 2005
19DCN, SFTPD
Identification and characterization of a novel interaction between pulmonary surfactant protein D and decorin.
Nadesalingam J, Bernal AL, Dodds AW, Willis AC, Mahoney DJ, Day AJ, Reid KB, Palaniyar N.
J Biol Chem 278(28):25678-87. Epub 2003 May 2. 2003
20DCN
Tumour necrosis factor-alpha interacts with biglycan and decorin.
Tufvesson E, Westergren-Thorsson G.
FEBS Lett. 530(1-3):124-8. 2003
21DCN
Decorin suppresses transforming growth factor-beta-induced expression of plasminogen activator inhibitor-1 in human mesangial cells through a mechanism that involves Ca2+-dependent phosphorylation of Smad2 at serine-240.
Abdel-Wahab N, Wicks SJ, Mason RM, Chantry A.
Biochem J 362(Pt 3):643-9. 2002
22DCN, FLNA
Leucine-rich repeat region of decorin binds to filamin-A.
Yoshida K, Suzuki Y, Honda E, Amemiya K, Nakatani T, Ebina M, Narumi K, Satoh K, Munakata H.
Biochimie 84(4):303-8. 2002
23DCN
The interaction of recombinant decorin with alpha2HS-glycoprotein-implications for structural and functional investigations.
Sugars RV, Waddington RJ, Embery G.
Protein Expr Purif. 25(1):180-8. 2002
24DCN
Molecular interactions of biglycan and decorin with elastic fiber components: biglycan forms a ternary complex with tropoelastin and microfibril-associated glycoprotein 1.
Reinboth B, Hanssen E, Cleary EG, Gibson MA.
J Biol Chem. 277(6):3950-7. 2002
25DCN, WISP1
WISP-1 binds to decorin and biglycan.
Desnoyers L, Arnott D, Pennica D.
J Biol Chem 276(50):47599-607. 2001
26DCN
An anti-oncogenic role for decorin. Down-regulation of ErbB2 leads to growth suppression and cytodifferentiation of mammary carcinoma cells.
Santra M, Eichstetter I, Iozzo RV.
J Biol Chem 275(45):35153-61. 2000
27BGN, DCN, EPYC, FMOD, KERA, LUM, OMD, PRELP, OGN
Super-motifs and evolution of tandem leucine-rich repeats within the small proteoglycans--biglycan, decorin, lumican, fibromodulin, PRELP, keratocan, osteoadherin, epiphycan, and osteoglycin.
Matsushima N, Ohyanagi T, Tanaka T, Kretsinger RH.
Proteins 38(2):210-25. 2000
28DCN
Molecular basis for the association of group IIA phospholipase A(2) and decorin in human atherosclerotic lesions.
Sartipy P, Johansen B, Gâsvik K, Hurt-Camejo E.
Circ Res. 86(6):707-14. 2000
29DCN
Expression of proteoglycan decorin in neural retina.
Inatani M, et al.
Invest Ophthalmol Vis Sci 40(8):1783-91 1999
30DCN
Decorin is a biological ligand for the epidermal growth factor receptor.
Iozzo RV, Moscatello DK, McQuillan DJ, Eichstetter I.
J Biol Chem. 274(8):4489-92. 1999
31DCN
Decorin suppresses tumor cell growth by activating the epidermal growth factor receptor.
Moscatello DK, Santra M, Mann DM, McQuillan DJ, Wong AJ, Iozzo RV.
J Clin Invest 101(2):406-12. 1998
32DCN
Decorin core protein fragment Leu155-Val260 interacts with TGF-beta but does not compete for decorin binding to type I collagen
Schönherr E, Broszat M, Brandan E, Bruckner P, Kresse H.
Arch Biochem Biophys. 355(2):241-8. 1998
33DCN
The proteoglycan decorin links low density lipoproteins with collagen type I.
PentikŠinen MO, et al.
J Biol Chem 272 : 7633-7638. 1997
34DCN
Localization of a binding site for the proteoglycan decorin on collagen XIV (undulin).
Ehnis T, Dieterich W, Bauer M, Kresse H, Schuppan D.
J Biol Chem. 272(33):20414-9. 1997
35DCN
Degradation of decorin by matrix metalloproteinases: identification of the cleavage sites, kinetic analyses and transforming growth factor-beta1 release.
Imai K, Hiramatsu A, Fukushima D, Pierschbacher MD, Okada Y.
Biochem J. 322 ( Pt 3):809-14. 1997
36BGN, DCN, FMOD
Single-strand conformation polymorphism analysis of human decorin, biglycan and fibromodulin cDNAs.
Sztrolovics R, et al.
Matrix Biol 14 : 307-312. 1994
37DCN
The murine decorin. Complete cDNA cloning, genomic organization, chromosomal assignment, and expression during organogenesis and tissue differentiation.
Scholzen T, Solursh M, Suzuki S, Reiter R, Morgan JL, Buchberg AM, Siracusa LD, Iozzo RV.
J Biol Chem 269(45):28270-81. 1994
38DCN
Length polymorphism within a complex dinucleotide repeat in the human decorin (DCN) gene.
Briggs MD, et al.
Hum Mol Genet 2 : 1087. 1993
39DCN
Human decorin gene : intron-exon junctions and chromosomal localization.
Vetter U, et al.
Genomics 15 : 161-168. 1993
40DCN
The human decorin gene : intron-exon organization, discovery of two alternatively spliced exons in the 5' untranslated region, and mapping of the gene to chromosome 12q23.
Danielson KG, et al.
Genomics 15 : 146-160. 1993
41DCN
Interaction of heparin cofactor II with biglycan and decorin.
Whinna HC, Choi HU, Rosenberg LC, Church FC.
J Biol Chem. 268(6):3920-4. 1993
42DCN
Expression of decorin in human tissues and cell lines and defined chromosomal assignment of the gene locus (DCN).
Pulkkinen L, Alitalo T, Krusius T, Peltonen L.
Cytogenet Cell Genet 60(2):107-11. 1992
43DCN
The proteoglycan decorin binds C1q and inhibits the activity of the C1 complex.
Krumdieck R, Höök M, Rosenberg LC, Volanakis JE.
J Immunol. 149(11):3695-701. 1992
44DCN
Interactions between thrombospondin and the small proteoglycan decorin: interference with cell attachment.
Winnemöller M, Schön P, Vischer P, Kresse H.
Eur J Cell Biol. 59(1):47-55. 1992
45DCN
Binding of the proteoglycan decorin to collagen type VI.
Bidanset DJ, Guidry C, Rosenberg LC, Choi HU, Timpl R, Hook M.
J Biol Chem. 267(8):5250-6. 1992
46DCN
Gene expression and localization of the human decorin gene (DCN).
Alitalo T, et al.
(HGM11) Cytogenet Cell Genet 58 : 1976. 1991
47DCN, BGN
In situ localization of decorin and biglycan on chromosomes 12 and X.
Just W, et al.
(HGM11) Cytogenet Cell Genet 58 : 1977. 1991
48COL2A1, DCN
Decorin interacts with fibrillar collagen of embryonic and adult human skin.
Fleischmajer R, Fisher LW, MacDonald ED, Jacobs L Jr, Perlish JS, Termine JD.
J Struct Biol 106(1):82-90. 1991
49DCN, BGN
Localization of PGI (Biglycan, BGN) and PGII (Decorin, DCN, PG-40) genes on human chromosomes Xq13-qter and 12q, respectively.
McBride OW, et al.
Genomics 6 : 219-225. 1990
50DCN
Deficient expression of the gene coding for decorin in a lethal form of Marfan syndrome.
Pulkkinen L, Kainulainen K, Krusius T, Makinen P, Schollin J, Gustavsson KH, Peltonen L.
J Biol Chem 265(29):17780-5. 1990
51DCN
Deduced protein sequence of bone small proteoglycan I (biglycan) shows homology with proteoglycan II (decorin) and several nonconnective tissue proteins in a variety of species.
Fisher LW, Termine JD, Young MF.
J Biol Chem 264(8):4571-6. 1989
52DCN
Primary structure of an extracellular matrix proteoglycan core protein deduced from cloned cDNA.
Krusius T, Ruoslahti E.
Proc Natl Acad Sci U S A 83(20):7683-7. 1986