| 1 | DCN, ITGB1, WNT7A
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| Integrin signalling regulates the expansion of neuroepithelial progenitors and neurogenesis via Wnt7a and Decorin.
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| Long K, Moss L, Laursen L, Boulter L, ffrench-Constant C.
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| Nat Commun 7:10354. doi: 10.1038/ncomms10354.
2016
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| 2 | BGN, DCN
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| The small leucine-rich proteoglycan BGN accumulates in CADASIL and binds to NOTCH3.
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| Zhang X, Lee SJ, Young MF, Wang MM.
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| Transl Stroke Res 6(2):148-55. doi: 10.1007/s12975-014-0379-1. Epub 2015 Jan 13.
2015
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| 3 | BGN, DCN
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| The tendon injury response is influenced by decorin and biglycan.
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| Dunkman AA, Buckley MR, Mienaltowski MJ, Adams SM, Thomas SJ, Satchell L, Kumar A, Pathmanathan L, Beason DP, Iozzo RV, Birk DE, Soslowsky LJ.
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| Ann Biomed Eng 42(3):619-30. doi: 10.1007/s10439-013-0915-2. Epub 2013 Sep 27.
2014
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| 4 | DCN, VIM
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| The dermatan sulfate proteoglycan decorin modulates α2β1 integrin and the vimentin intermediate filament system during collagen synthesis.
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| Jungmann O, Nikolovska K, Stock C, Schulz JN, Eckes B, Riethmüller C, Owens RT, Iozzo RV, Seidler DG.
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| PLoS One 7(12):e50809. doi: 10.1371/journal.pone.0050809. Epub 2012 Dec 3.
2012
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| 5 | DCN, SPARC, SPRY1, TSKU
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| Stromal expression of decorin, Semaphorin6D, SPARC, Sprouty1 and Tsukushi in developing prostate and decreased levels of decorin in prostate cancer.
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| Henke A, Grace OC, Ashley GR, Stewart GD, Riddick AC, Yeun H, O'Donnell M, Anderson RA, Thomson AA.
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| PLoS One 7(8):e42516. doi: 10.1371/journal.pone.0042516. Epub 2012 Aug 3.
2012
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| 6 | CTGF, DCN
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| Decorin interacts with CTGF/CCN2 through LRR12 inhibiting its biological activity.
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| Vial C, Gutierrez J, Santander C, Cabrera D, Brandan E.
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| J Biol Chem. 2011
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| 7 | CTGF, DCN
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| Decorin interacts with connective tissue growth factor (CTGF)/CCN2 by LRR12 inhibiting its biological activity.
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| Vial C, Gutiérrez J, Santander C, Cabrera D, Brandan E.
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| J Biol Chem 286(27):24242-52. Epub 2011 Mar 23.
2011
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| 8 | BMP1, DCN
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| Decorin is processed by three isoforms of bone morphogenetic protein-1 (BMP1).
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| von Marschall Z, Fisher LW.
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| Biochem Biophys Res Commun 391(3):1374-8. Epub 2009 Dec 22.
2010
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| 9 | ATCS, CHST14, DCN
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| Loss-of-function mutations of CHST14 in a new type of Ehlers-Danlos syndrome.
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| Miyake N, Kosho T, Mizumoto S, Furuichi T, Hatamochi A, Nagashima Y, Arai E, Takahashi K, Kawamura R, Wakui K, Takahashi J, Kato H, Yasui H, Ishida T, Ohashi H, Nishimura G, Shiina M, Saitsu H, Tsurusaki Y, Doi H, Fukushima Y, Ikegawa S, Yamada S, Sugahara K, Matsumoto N.
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| Hum Mutat 31(8):966-74.PMID: 20533528 2010
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| 10 | DCN
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| Decorin accumulation contributes to the stromal opacities found in congenital stromal corneal dystrophy.
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| Bredrup C, Stang E, Bruland O, Palka BP, Young RD, Haavik J, Knappskog PM, Rødahl E.
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| Invest Ophthalmol Vis Sci. 51(11):5578-82. 2010
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| 11 | BGN, DCN
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| Genetic evidence for the coordinated regulation of collagen fibrillogenesis in the cornea by decorin and biglycan.
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| Zhang G, Chen S, Goldoni S, Calder BW, Simpson HC, Owens RT, McQuillan DJ, Young MF, Iozzo RV, Birk DE.
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| J Biol Chem 284(13):8888-97. Epub 2009 Jan 9.
2009
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| 12 | BGN, DCN
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| Genetic evidence for key roles of decorin and biglycan in dentin mineralization.
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| Haruyama N, Sreenath TL, Suzuki S, Yao X, Wang Z, Wang Y, Honeycutt C, Iozzo RV, Young MF, Kulkarni AB.
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| Matrix Biol 28(3):129-36. Epub 2009 Feb 12.
2009
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| 13 | DCN
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| Decorin promotes robust axon growth on inhibitory CSPGs and myelin via a direct effect on neurons.
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| Minor K, Tang X, Kahrilas G, Archibald SJ, Davies JE, Davies SJ.
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| Neurobiol Dis 32(1):88-95. Epub 2008 Jun 26.
2008
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| 14 | DCN, NR1H4
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| Upregulation of decorin by FXR in vascular smooth muscle cells.
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| He F, Zhang Q, Kuruba R, Gao X, Li J, Li Y, Gong W, Jiang Y, Xie W, Li S.
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| Biochem Biophys Res Commun 372(4):746-51. Epub 2008 Jun 2.
2008
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| 15 | DCN
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| Differential expression of decorin by human malignant and benign vascular tumors.
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| Salomäki HH, Sainio AO, Söderström M, Pakkanen S, Laine J, Järveläinen HT.
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| J Histochem Cytochem 56(7):639-46. Epub 2008 Apr 14.
2008
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| 16 | DCN
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| Decorin derived antiangiogenic peptide LRR5 inhibits endothelial cell migration by interfering with VEGF-stimulated NO release.
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| Fan H, Sulochana KN, Chong YS, Ge R.
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| Int J Biochem Cell Biol 40(10):2120-8. Epub 2008 Feb 17.
2008
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| 17 | DCN,DIO1,DIO2
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| Gene expression profiles reveal that DCN, DIO1, and DIO2 are underexpressed in benign and malignant thyroid tumors.
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| Arnaldi LA, Borra RC, Maciel RM, Cerutti JM.
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| Thyroid 15(3):210-21. 2005
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| 18 | CSCD, DCN
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| Congenital stromal dystrophy of the cornea caused by a mutation in the decorin gene.
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| Bredrup C, Knappskog PM, Majewski J, Rødahl E, Boman H.
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| Invest Ophthalmol Vis Sci 46(2):420-6. 2005
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| 19 | DCN, SFTPD
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| Identification and characterization of a novel interaction between pulmonary surfactant protein D and decorin.
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| Nadesalingam J, Bernal AL, Dodds AW, Willis AC, Mahoney DJ, Day AJ, Reid KB, Palaniyar N.
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| J Biol Chem 278(28):25678-87. Epub 2003 May 2. 2003
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| 20 | DCN
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| Tumour necrosis factor-alpha interacts with biglycan and decorin.
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| Tufvesson E, Westergren-Thorsson G.
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| FEBS Lett. 530(1-3):124-8. 2003
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| 21 | DCN
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| Decorin suppresses transforming growth factor-beta-induced expression of plasminogen activator inhibitor-1 in human mesangial cells through a mechanism that involves Ca2+-dependent phosphorylation of Smad2 at serine-240.
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| Abdel-Wahab N, Wicks SJ, Mason RM, Chantry A.
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| Biochem J 362(Pt 3):643-9. 2002
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| 22 | DCN, FLNA
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| Leucine-rich repeat region of decorin binds to filamin-A.
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| Yoshida K, Suzuki Y, Honda E, Amemiya K, Nakatani T, Ebina M, Narumi K, Satoh K, Munakata H.
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| Biochimie 84(4):303-8. 2002
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| 23 | DCN
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| The interaction of recombinant decorin with alpha2HS-glycoprotein-implications for structural and functional investigations.
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| Sugars RV, Waddington RJ, Embery G.
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| Protein Expr Purif. 25(1):180-8. 2002
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| 24 | DCN
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| Molecular interactions of biglycan and decorin with elastic fiber components: biglycan forms a ternary complex with tropoelastin and microfibril-associated glycoprotein 1.
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| Reinboth B, Hanssen E, Cleary EG, Gibson MA.
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| J Biol Chem. 277(6):3950-7. 2002
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| 25 | DCN, WISP1
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| WISP-1 binds to decorin and biglycan.
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| Desnoyers L, Arnott D, Pennica D.
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| J Biol Chem 276(50):47599-607. 2001
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| 26 | DCN
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| An anti-oncogenic role for decorin. Down-regulation of ErbB2 leads to growth suppression and cytodifferentiation of mammary carcinoma cells.
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| Santra M, Eichstetter I, Iozzo RV.
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| J Biol Chem 275(45):35153-61. 2000
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| 27 | BGN, DCN, EPYC, FMOD, KERA, LUM, OMD, PRELP, OGN
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| Super-motifs and evolution of tandem leucine-rich repeats within the small proteoglycans--biglycan, decorin, lumican, fibromodulin, PRELP, keratocan, osteoadherin, epiphycan, and osteoglycin.
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| Matsushima N, Ohyanagi T, Tanaka T, Kretsinger RH.
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| Proteins 38(2):210-25. 2000
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| 28 | DCN
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| Molecular basis for the association of group IIA phospholipase A(2) and decorin in human atherosclerotic lesions.
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| Sartipy P, Johansen B, Gâsvik K, Hurt-Camejo E.
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| Circ Res. 86(6):707-14. 2000
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| 29 | DCN
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| Expression of proteoglycan decorin in neural retina.
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| Inatani M, et al.
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| Invest Ophthalmol Vis Sci 40(8):1783-91 1999
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| 30 | DCN
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| Decorin is a biological ligand for the epidermal growth factor receptor.
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| Iozzo RV, Moscatello DK, McQuillan DJ, Eichstetter I.
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| J Biol Chem. 274(8):4489-92. 1999
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| 31 | DCN
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| Decorin suppresses tumor cell growth by activating the epidermal growth factor receptor.
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| Moscatello DK, Santra M, Mann DM, McQuillan DJ, Wong AJ, Iozzo RV.
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| J Clin Invest 101(2):406-12. 1998
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| 32 | DCN
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| Decorin core protein fragment Leu155-Val260 interacts with TGF-beta but does not compete for decorin binding to type I collagen
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| Schönherr E, Broszat M, Brandan E, Bruckner P, Kresse H.
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| Arch Biochem Biophys. 355(2):241-8. 1998
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| 33 | DCN
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| The proteoglycan decorin links low density lipoproteins with collagen type I.
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| PentikŠinen MO, et al.
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| J Biol Chem 272 : 7633-7638. 1997
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| 34 | DCN
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| Localization of a binding site for the proteoglycan decorin on collagen XIV (undulin).
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| Ehnis T, Dieterich W, Bauer M, Kresse H, Schuppan D.
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| J Biol Chem. 272(33):20414-9. 1997
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| 35 | DCN
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| Degradation of decorin by matrix metalloproteinases: identification of the cleavage sites, kinetic analyses and transforming growth factor-beta1 release.
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| Imai K, Hiramatsu A, Fukushima D, Pierschbacher MD, Okada Y.
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| Biochem J. 322 ( Pt 3):809-14. 1997
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| 36 | BGN, DCN, FMOD
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| Single-strand conformation polymorphism analysis of human decorin, biglycan and fibromodulin cDNAs.
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| Sztrolovics R, et al.
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| Matrix Biol 14 : 307-312. 1994
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| 37 | DCN
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| The murine decorin. Complete cDNA cloning, genomic organization, chromosomal assignment, and expression during organogenesis and tissue differentiation.
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| Scholzen T, Solursh M, Suzuki S, Reiter R, Morgan JL, Buchberg AM, Siracusa LD, Iozzo RV.
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| J Biol Chem 269(45):28270-81. 1994
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| 38 | DCN
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| Length polymorphism within a complex dinucleotide repeat in the human decorin (DCN) gene.
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| Briggs MD, et al.
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| Hum Mol Genet 2 : 1087. 1993
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| 39 | DCN
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| Human decorin gene : intron-exon junctions and chromosomal localization.
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| Vetter U, et al.
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| Genomics 15 : 161-168. 1993
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| 40 | DCN
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| The human decorin gene : intron-exon organization, discovery of two alternatively spliced exons in the 5' untranslated region, and mapping of the gene to chromosome 12q23.
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| Danielson KG, et al.
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| Genomics 15 : 146-160. 1993
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| 41 | DCN
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| Interaction of heparin cofactor II with biglycan and decorin.
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| Whinna HC, Choi HU, Rosenberg LC, Church FC.
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| J Biol Chem. 268(6):3920-4. 1993
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| 42 | DCN
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| Expression of decorin in human tissues and cell lines and defined chromosomal assignment of the gene locus (DCN).
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| Pulkkinen L, Alitalo T, Krusius T, Peltonen L.
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| Cytogenet Cell Genet 60(2):107-11. 1992
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| 43 | DCN
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| The proteoglycan decorin binds C1q and inhibits the activity of the C1 complex.
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| Krumdieck R, Höök M, Rosenberg LC, Volanakis JE.
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| J Immunol. 149(11):3695-701. 1992
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| 44 | DCN
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| Interactions between thrombospondin and the small proteoglycan decorin: interference with cell attachment.
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| Winnemöller M, Schön P, Vischer P, Kresse H.
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| Eur J Cell Biol. 59(1):47-55. 1992
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| 45 | DCN
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| Binding of the proteoglycan decorin to collagen type VI.
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| Bidanset DJ, Guidry C, Rosenberg LC, Choi HU, Timpl R, Hook M.
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| J Biol Chem. 267(8):5250-6. 1992
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| 46 | DCN
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| Gene expression and localization of the human decorin gene (DCN).
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| Alitalo T, et al.
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| (HGM11) Cytogenet Cell Genet 58 : 1976. 1991
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| 47 | DCN, BGN
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| In situ localization of decorin and biglycan on chromosomes 12 and X.
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| Just W, et al.
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| (HGM11) Cytogenet Cell Genet 58 : 1977. 1991
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| 48 | COL2A1, DCN
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| Decorin interacts with fibrillar collagen of embryonic and adult human skin.
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| Fleischmajer R, Fisher LW, MacDonald ED, Jacobs L Jr, Perlish JS, Termine JD.
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| J Struct Biol 106(1):82-90. 1991
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| 49 | DCN, BGN
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| Localization of PGI (Biglycan, BGN) and PGII (Decorin, DCN, PG-40) genes on human chromosomes Xq13-qter and 12q, respectively.
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| McBride OW, et al.
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| Genomics 6 : 219-225. 1990
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| 50 | DCN
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| Deficient expression of the gene coding for decorin in a lethal form of Marfan syndrome.
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| Pulkkinen L, Kainulainen K, Krusius T, Makinen P, Schollin J, Gustavsson KH, Peltonen L.
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| J Biol Chem 265(29):17780-5. 1990
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| 51 | DCN
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| Deduced protein sequence of bone small proteoglycan I (biglycan) shows homology with proteoglycan II (decorin) and several nonconnective tissue proteins in a variety of species.
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| Fisher LW, Termine JD, Young MF.
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| J Biol Chem 264(8):4571-6. 1989
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| 52 | DCN
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| Primary structure of an extracellular matrix proteoglycan core protein deduced from cloned cDNA.
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| Krusius T, Ruoslahti E.
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| Proc Natl Acad Sci U S A 83(20):7683-7. 1986
|