1 | DCLK1
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| Role of DCLK1 in oncogenic signaling (Review)
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| Lu Q, Feng H, Chen H, Weygant N, Du J, Yan Z, Cao Z
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| Int J Oncol. Nov;61(5):137. doi: 10.3892/ijo.2022.5427. Epub 2022 Sep 23 2022
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2 | DCLK1
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| Targeting Doublecortin-Like Kinase 1 (DCLK1)-Regulated SARS-CoV-2 Pathogenesis in COVID-19
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| Undi RB, Larabee JL, Filiberti A, Ulahannan S, Aravindan S, Stroberg E, Barton LM, Duval EJ, Mukhopadhyay S, Henthorn JC, Akins D, Houchen CW, Huycke MM, Ali N.
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| J Virol. Sep 14;96(17):e0096722. doi: 10.1128/jvi.00967-22. Epub 2022 Aug 9. 2022
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3 | DCLK1
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| Autoregulatory control of microtubule binding in doublecortin-like kinase 1.
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| Agulto RL, Rogers MM, Tan TC, Ramkumar A, Downing AM, Bodin H, Castro J, Nowakowski DW, Ori-McKenney KM.
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| Elife Jul 26;10:e60126. doi: 10.7554/eLife.60126 2021
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4 | DCLK1
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| Dclk1 in tuft cells promotes inflammation-driven epithelial restitution and mitigates chronic colitis
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| Yi J, Bergstrom K, Fu J, Shan X, McDaniel JM, McGee S, Qu D, Houchen CW, Liu X, Xia L.
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| Cell Death Differ. C 2019 Sep;26(9):1656-1669. doi: 10.1038/s41418-018-0237-x. Epub 2018 Nov 26 2019
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5 | DCLK1
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| DCLK1 Plays a Metastatic-Promoting Role in Human Breast Cancer Cells
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| Liu H, Wen T, Zhou Y, Fan X, Du T, Gao T, Li L, Liu J, Yang L, Yao J, Ge Y, An G.
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| Biomed Res Int. May 15;2019:1061979. doi: 10.1155/2019/1061979 2019
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6 | DCLK1
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| Functional implication of Dclk1 and Dclk1-expressing cells in cancer
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| Westphalen CB, Quante M, Wang TC.
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| Small GTPases. Jul 3;8(3):164-171. doi: 10.1080/21541248.2016.1208792. Epub 2016 Jul 26. 2017
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7 | DCLK1
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| Doublecortin-like kinase 1-positive enterocyte - a new cell type in human intestine.
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| Leppänen J, Helminen O, Huhta H, Kauppila JH, Miinalainen I, Ronkainen VP, Saarnio J, Lehenkari PP, Karttunen TJ.
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| APMIS PMIS. 2016 Sep 28. doi: 10.1111/apm.12599. [Epub ahead of print]
2016
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8 | DCLK1
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| Biochemical and Structural Insights into Doublecortin-like Kinase Domain 1.
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| Patel O, Dai W, Mentzel M, Griffin MD, Serindoux J, Gay Y, Fischer S, Sterle S, Kropp A, Burns CJ, Ernst M, Buchert M, Lucet IS.
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| Structure 24(9):1550-61. doi: 10.1016/j.str.2016.07.008. Epub 2016 Aug 18.
2016
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9 | DCLK1
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| DCLK1 is up-regulated and associated with metastasis and prognosis in colorectal cancer.
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| Gao T, Wang M, Xu L, Wen T, Liu J, An G.
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| J Cancer Res Clin Oncol 142(10):2131-40. doi: 10.1007/s00432-016-2218-0. Epub 2016 Aug 12.
2016
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10 | DCLK1, MAP7D1
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| DCLK1 phosphorylates the microtubule-associated protein MAP7D1 to promote axon elongation in cortical neurons.
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| Koizumi H, Fujioka H, Togashi K, Thompson J, Yates JR 3rd, Gleeson JG, Emoto K.
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| Dev Neurobiol ev Neurobiol. 2016 Aug 9. doi: 10.1002/dneu.22428. [Epub ahead of print]
2016
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11 | DCLK1
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| Functional implication of Dclk1 and Dclk1-expressing cells in cancer.
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| Westphalen CB, Quante M, Wang TC.
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| Small GTPases mall GTPases. 2016 Jul 26:1-8. [Epub ahead of print]
2016
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12 | DCLK1, KIF1A
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| Microtubule-binding protein doublecortin-like kinase 1 (DCLK1) guides kinesin-3-mediated cargo transport to dendrites.
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| Lipka J, Kapitein LC, Jaworski J, Hoogenraad CC.
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| EMBO J 35(3):302-18. doi: 10.15252/embj.201592929. Epub 2016 Jan 12.
2016
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13 | DCLK1
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| Plasma DCLK1 is a marker of hepatocellular carcinoma (HCC): Targeting DCLK1 prevents HCC tumor xenograft growth via a microRNA-dependent mechanism.
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| Sureban SM, Madhoun MF, May R, Qu D, Ali N, Fazili J, Weygant N, Chandrakesan P, Ding K, Lightfoot SA, Houchen CW.
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| Oncotarget 6(35):37200-15. doi: 10.18632/oncotarget.5808.
2015
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14 | DCLK1, JDP2
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| Nuclear translocation of doublecortin-like protein kinase and phosphorylation of a transcription factor JDP2.
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| Nagamine T, Nomada S, Onouchi T, Kameshita I, Sueyoshi N.
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| Biochem Biophys Res Commun 446(1):73-8. doi: 10.1016/j.bbrc.2014.02.075. Epub 2014 Feb 25.
2014
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15 | DCLK1
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| DCLK1 facilitates intestinal tumor growth via enhancing pluripotency and epithelial mesenchymal transition.
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| Chandrakesan P, Weygant N, May R, Qu D, Chinthalapally HR, Sureban SM, Ali N, Lightfoot SA, Umar S, Houchen CW.
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| Oncotarget 5(19):9269-80.
2014
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16 | ANK2, ARSG, CDH13, DCLK1, GRM8, RIMBP2, SLC16A6
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| Expression and replication studies to identify new candidate genes involved in normal hearing function.
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| Girotto G, Vuckovic D, Buniello A, Lorente-Cánovas B, Lewis M, Gasparini P, Steel KP.
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| PLoS One 9(1):e85352. doi: 10.1371/journal.pone.0085352. eCollection 2014. Erratum in: PLoS One. 2014;9(3):e91446.
2014
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17 | DCLK1, RUNX2
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| The microtubule-associated protein DCAMKL1 regulates osteoblast function via repression of Runx2.
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| Zou W, Greenblatt MB, Brady N, Lotinun S, Zhai B, de Rivera H, Singh A, Sun J, Gygi SP, Baron R, Glimcher LH, Jones DC.
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| J Exp Med 210(9):1793-806. doi: 10.1084/jem.20111790. Epub 2013 Aug 5.
2013
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18 | DCLK1
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| Dclk1 distinguishes between tumor and normal stem cells in the intestine
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| Nakanishi Y, Seno H, Fukuoka A, Ueo T, Yamaga Y, Maruno T, Nakanishi N, Kanda K, Komekado H, Kawada M, Isomura A, Kawada K, Sakai Y, Yanagita M, Kageyama R, Kawaguchi Y, Taketo MM, Yonehara S, Chiba T.
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| Nat Genet. Jan;45(1):98-103. doi: 10.1038/ng.2481. Epub 2012 Dec 2. 2013
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19 | DCLK1, DCX, KIF1A
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| Molecular basis for specific regulation of neuronal kinesin-3 motors by doublecortin family proteins.
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| Liu JS, Schubert CR, Fu X, Fourniol FJ, Jaiswal JK, Houdusse A, Stultz CM, Moores CA, Walsh CA.
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| Mol Cell 47(5):707-21. doi: 10.1016/j.molcel.2012.06.025. Epub 2012 Aug 1. 2012
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20 | DCLK1, DCX
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| A novel role for doublecortin and doublecortin-like kinase in regulating growth cone microtubules.
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| Jean DC, Baas PW, Black MM.
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| Hum Mol Genet 21(26):5511-27. doi: 10.1093/hmg/dds395. Epub 2012 Sep 21.
2012
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21 | DCLK1
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| Doublecortin and doublecortin-like are expressed in overlapping and non-overlapping neuronal cell population: implications for neurogenesis.
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| Saaltink DJ, Håvik B, Verissimo CS, Lucassen PJ, Vreugdenhil E.
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| J Comp Neurol 520(13):2805-23. doi: 10.1002/cne.23144.
2012
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22 | CMIP, DCLK1, GRM8, PTPRD
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| Hearing function and thresholds: a genome-wide association study in European isolated populations identifies new loci and pathways.
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| Girotto G, Pirastu N, Sorice R, Biino G, Campbell H, d'Adamo AP, Hastie ND, Nutile T, Polasek O, Portas L, Rudan I, Ulivi S, Zemunik T, Wright AF, Ciullo M, Hayward C, Pirastu M, Gasparini P.
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| J Med Genet 48(6):369-74. doi: 10.1136/jmg.2010.088310. Epub 2011 Apr 14.
2011
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23 | DCLK1
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| Gastric tuft cells express DCLK1 and are expanded in hyperplasia.
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| Saqui-Salces M, Keeley TM, Grosse AS, Qiao XT, El-Zaatari M, Gumucio DL, Samuelson LC, Merchant JL.
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| Histochem Cell Biol 136(2):191-204. doi: 10.1007/s00418-011-0831-1. Epub 2011 Jun 18.
2011
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24 | DCLK1
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| Silencing of the microtubule-associated proteins doublecortin-like and doublecortin-like kinase-long induces apoptosis in neuroblastoma cells.
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| Verissimo CS, Molenaar JJ, Meerman J, Puigvert JC, Lamers F, Koster J, Danen EH, van de Water B, Versteeg R, Fitzsimons CP, Vreugdenhil E.
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| Endocr Relat Cancer 17(2):399-414. doi: 10.1677/ERC-09-0301. Print 2010 Jun.
2010
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25 | DCLK1
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| Variants in doublecortin- and calmodulin kinase like 1, a gene up-regulated by BDNF, are associated with memory and general cognitive abilities.
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| Le Hellard S, Håvik B, Espeseth T, Breilid H, Løvlie R, Luciano M, Gow AJ, Harris SE, Starr JM, Wibrand K, Lundervold AJ, Porteous DJ, Bramham CR, Deary IJ, Reinvang I, Steen VM.
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| PLoS One 4(10):e7534. doi: 10.1371/journal.pone.0007534.
2009
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26 | DCLK1, DCLK2
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| Alternative transcripts of Dclk1 and Dclk2 and their expression in doublecortin knockout mice.
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| Tuy FP, Saillour Y, Kappeler C, Chelly J, Francis F.
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| Dev Neurosci 30(1-3):171-86.
2008
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27 | DCLK1
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| The microtubule-associated protein doublecortin-like regulates the transport of the glucocorticoid receptor in neuronal progenitor cells.
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| Fitzsimons CP, Ahmed S, Wittevrongel CF, Schouten TG, Dijkmans TF, Scheenen WJ, Schaaf MJ, de Kloet ER, Vreugdenhil E.
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| Mol Endocrinol 22(2):248-62. Epub 2007 Nov 1.
2008
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28 | DCLK1
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| Doublecortin-like, a microtubule-associated protein expressed in radial glia, is crucial for neuronal precursor division and radial process stability.
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| Vreugdenhil E, Kolk SM, Boekhoorn K, Fitzsimons CP, Schaaf M, Schouten T, Sarabdjitsingh A, Sibug R, Lucassen PJ.
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| Eur J Neurosci 25(3):635-48.
2007
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29 | DCLK1
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| Doublecortin-like kinase functions with doublecortin to mediate fiber tract decussation and neuronal migration.
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| Koizumi H, Tanaka T, Gleeson JG.
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| Neuron 49(1):55-66.
2006
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30 | DCLK1
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| Doublecortin-like kinase controls neurogenesis by regulating mitotic spindles and M phase progression.
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| Shu T, Tseng HC, Sapir T, Stern P, Zhou Y, Sanada K, Fischer A, Coquelle FM, Reiner O, Tsai LH.
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| Neuron 49(1):25-39.
2006
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31 | DCLK1
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| Functional differences between two DCLK splice variants.
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| Engels BM, Schouten TG, van Dullemen J, Gosens I, Vreugdenhil E.
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| Brain Res Mol Brain Res 120(2):103-14.
2004
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32 | DCLK1
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| Alternative splice variants of doublecortin-like kinase are differentially expressed and have different kinase activities.
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| Burgess HA, Reiner O.
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| J Biol Chem 277(20):17696-705. Epub 2002 Mar 7. 2002
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33 | DCLK1, DCX
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| Doublecortin mutations cluster in evolutionarily conserved functional domains.
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| Sapir T, Horesh D, Caspi M, Atlas R, Burgess HA, Wolf SG, Francis F, Chelly J, Elbaum M, Pietrokovski S, Reiner O.
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| Hum Mol Genet 9(5):703-12. 2000
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34 | DCLK1, MICU2
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| DCAMKL1 encodes a protein kinase with homology to doublecortin that regulates microtubule polymerization.
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| Lin PT, Gleeson JG, Corbo JC, Flanagan L, Walsh CA.
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| J Neurosci 20(24):9152-61. 2000
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35 | DCLK1
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| DCAMKL1, a brain-specific transmembrane protein on 13q12.3 that is similar to doublecortin.
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| Sossey-Alaoui K, et al.
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| Genomics 56(1):121-6. 1999
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36 | DCLK1
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| Genomic Structure, Chromosomal Mapping, and Expression Pattern of Human DCAMKL1 (KIAA0369), a Homologue of DCX (XLIS).
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| Matsumoto N, et al.
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| Genomics 56(2):179-183. 1999
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37 | DCLK1
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| Expression and chromosomal localization of KIAA0369, a putative kinase structurally related to Doublecortin.
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| Omori Y, et al.
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| J Hum Genet 43(3):169-77. 1998
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38 | ADAMTS3, AKAP6, ALMS1, ANKRD28, AREL1, ARHGEF10, ARHGEF11, ARHGEF17, ARNT2, BAZ2A, CABIN1, CAST, CHD9, CIC, CLEC16A, CLOCK, CTNND1, DCLK1, DDX46, DIDO1, DNAH9, DNM3, DOCK3, DYNC1H1, ECM29, ENTPD4, EPB41L1, EZH1, FRMPD4, GCC2, HECW1, HERC2, HISPPD1, HUWE1, IGSF1, KAT6B, KHNYN, KIAA0319, KIAA0355, KIAA0379, KIF3B, KMT2B, LBA1, MADD, MAST4, MCF2L, MDN1, MTMR3, MYO6, N4BP3, NACAD, NRCAM, PCDH9, PCDHGA8, PCDHGC3, PDZD2, PER2, PFAS, PLEKHM1, PLXNB2, PRORP, PRUNE2, PTPRN2, RAPGEF2, RIMBP2, RIMS1, RIPOR2, RUSC2, SALL2, SEC16A, SEMA3C, SEMA3E, SETD1A, SFRS14, SNPH, SPECC1L, SPTBN2, SR140, SRCAP, SRRM2, SYNJ2, TECPR2, TLN2, TRIM66, TTC37, UBR2, WNK1, XPO6, ZBTB39, ZBTB5, ZFYVE16, ZFYVE26, ZMYM3, ZNF518A, ZNF609, ZNF629, ZNF646
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| Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.
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| Nagase T, Ishikawa K, Nakajima D, Ohira M, Seki N, Miyajima N, Tanaka A,Kotani H, Nomura N, Ohara O.
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| DNA Res 4(2):141-50. 1997
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