| 1 | DCC, NTN1, TUBB3
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| Human TUBB3 Mutations Disrupt Netrin Attractive Signaling
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| Huang H, Yang T, Shao Q, Majumder T, Mell K, Liu G.
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| Neuroscience. Mar 15;374:155-171. doi: 10.1016/j.neuroscience.2018.01.046. Epub 2018 Jan 31. 2018
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| 2 | DCC, NTN1, UNC5C
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| Unc5C and DCC act downstream of Ctip2 and Satb2 and contribute to corpus callosum formation.
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| Srivatsa S, Parthasarathy S, Britanova O, Bormuth I, Donahoo AL, Ackerman SL, Richards LJ, Tarabykin V.
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| Nat Commun 5:3708. doi: 10.1038/ncomms4708.
2014
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| 3 | DCC, NTN1, UNC5C
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| Netrin 1 and Dcc signalling are required for confinement of central axons within the central nervous system.
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| Laumonnerie C, Da Silva RV, Kania A, Wilson SI.
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| Development 141(3):594-603. doi: 10.1242/dev.099606.
2014
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| 4 | DCC, DSCAM, MAPK8, NTN1, UNC5C
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| c-Jun N-terminal kinase 1 (JNK1) is required for coordination of netrin signaling in axon guidance.
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| Qu C, Li W, Shao Q, Dwyer T, Huang H, Yang T, Liu G.
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| J Biol Chem 288(3):1883-95. doi: 10.1074/jbc.M112.417881. Epub 2012 Dec 6.
2013
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| 5 | DCC, UNC5C
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| unc5c haploinsufficient phenotype: striking similarities with the dcc haploinsufficiency model.
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| Auger ML, Schmidt ER, Manitt C, Dal-Bo G, Pasterkamp RJ, Flores C.
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| Eur J Neurosci 38(6):2853-63. doi: 10.1111/ejn.12270. Epub 2013 Jun 5.
2013
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| 6 | DCC
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| Deleted in colorectal carcinoma suppresses metastasis in p53-deficient mammary tumours.
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| Krimpenfort P, Song JY, Proost N, Zevenhoven J, Jonkers J, Berns A.
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| Nature 482(7386):538-41. doi: 10.1038/nature10790.
2012
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| 7 | DCC, DSCAM, NTN1, UNC5C
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| Down syndrome cell adhesion molecule (DSCAM) associates with uncoordinated-5C (UNC5C) in netrin-1-mediated growth cone collapse.
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| Purohit AA, Li W, Qu C, Dwyer T, Shao Q, Guan KL, Liu G.
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| J Biol Chem 287(32):27126-38. doi: 10.1074/jbc.M112.340174. Epub 2012 Jun 8.
2012
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| 8 | DCC, MYO10, NEO1
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| Differential regulation of myosin X movements by its cargos, DCC and neogenin.
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| Liu Y, Peng Y, Dai PG, Du QS, Mei L, Xiong WC.
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| J Cell Sci 125(Pt 3):751-62. doi: 10.1242/jcs.094946. Epub 2012 Feb 20.
2012
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| 9 | DCC, MMVC
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| A novel DCC mutation and genetic heterogeneity in congenital mirror movements.
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| Depienne C, Cincotta M, Billot S, Bouteiller D, Groppa S, Brochard V, Flamand C, Hubsch C, Meunier S, Giovannelli F, Klebe S, Corvol JC, Vidailhet M, Brice A, Roze E.
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| Neurology 76(3):260-4.
2011
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| 10 | DCC, PSEN1, ROBO1
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| Presenilin-dependent receptor processing is required for axon guidance.
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| Bai G, Chivatakarn O, Bonanomi D, Lettieri K, Franco L, Xia C, Stein E, Ma L, Lewcock JW, Pfaff SL.
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| Cell 144(1):106-18.
2011
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| 11 | DCC, MMVC
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| Mutations in DCC cause congenital mirror movements.
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| Srour M, Rivière JB, Pham JM, Dubé MP, Girard S, Morin S, Dion PA, Asselin G, Rochefort D, Hince P, Diab S, Sharafaddinzadeh N, Chouinard S, Théoret H, Charron F, Rouleau GA.
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| Science 328(5978):592.
2010
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| 12 | DCC
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| Transmembrane receptor DCC associates with protein synthesis machinery and regulates translation.
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| Tcherkezian J, Brittis PA, Thomas F, Roux PP, Flanagan JG.
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| Cell 141(4):632-44. Epub 2010 Apr 29.PMID: 20434207 2010
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| 13 | DCC, EPHB1, NTNG1, SEMA5A, SLIT3
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| Axon guidance and synaptic maintenance: preclinical markers for neurodegenerative disease and therapeutics.
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| Lin L, Lesnick TG, Maraganore DM, Isacson O.
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| Trends Neurosci 32(3):142-9. Epub 2009 Jan 21. Review.PMID: 19162339 2009
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| 14 | DCC
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| DCC promoter hypermethylation in esophageal squamous cell carcinoma.
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| Park HL, Kim MS, Yamashita K, Westra W, Carvalho AL, Lee J, Jiang WW, Baek JH, Liu J, Osada M, Moon CS, Califano JA, Mori M, Sidransky D.
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| Int J Cancer 122(11):2498-502.PMID: 18302152 2008
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| 15 | DCC, NTN1
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| The dependence receptor DCC requires lipid raft localization for cell death signaling.
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| Furne C, Corset V, Herincs Z, Cahuzac N, Hueber AO, Mehlen P.
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| Proc Natl Acad Sci U S A 103(11):4128-33. Epub 2006 Mar 6. 2006
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| 16 | DCC
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| DCC regulates cell adhesion in human colon cancer derived HT-29 cells and associates with ezrin.
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| Martin M, Simon-Assmann P, Kedinger M, Martin M, Mangeat P, Real FX, Fabre M.
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| Eur J Cell Biol 85(8):769-83. Epub 2006 Jun 8. 2006
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| 17 | DCC, MAPK1, MAPK3, NTN1
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| Netrin-1-mediated axon outgrowth requires deleted in colorectal cancer-dependent MAPK activation.
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| Forcet C, Stein E, Pays L, Corset V, Llambi F, Tessier-Lavigne M, Mehlen P.
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| Nature 417(6887):443-7. 2002
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| 18 | APPL1, DCC
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| Mediation of the DCC apoptotic signal by DIP13 alpha.
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| Liu J, Yao F, Wu R, Morgan M, Thorburn A, Finley RL Jr, Chen YQ.
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| J Biol Chem 277(29):26281-5. 2002
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| 19 | DCC, NTN1
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| Binding of DCC by netrin-1 to mediate axon guidance independent of adenosine A2B receptor activation.
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| Stein E, Zou Y, Poo M, Tessier-Lavigne M.
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| Science 291(5510):1976-82. 2001
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| 20 | DCC
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| The dependence receptor DCC (deleted in colorectal cancer) defines an alternative mechanism for caspase activation.
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| Forcet C, Ye X, Granger L, Corset V, Shin H, Bredesen DE, Mehlen P.
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| Proc Natl Acad Sci U S A 98(6):3416-3421. 2001
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| 21 | DCC, NTN1, UNC5C
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| Netrin-1 acts as a survival factor via its receptors UNC5H and DCC.
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| Llambi F, Causeret F, Bloch-Gallego E, Mehlen P.
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| EMBO J 20(11):2715-2722. 2001
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| 22 | DCC, NTN1, ROBO1
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| Hierarchical organization of guidance receptors: silencing of netrin attraction by slit through a Robo/DCC receptor complex.
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| Stein E, Tessier-Lavigne M.
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| Science 291(5510):1928-38. 2001
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| 23 | DCC, SMAD4
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| Homozygous deletions inactivate DCC, but not MADH4/DPC4/SMAD4, in a subset of pancreatic and biliary cancers.
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| Hilgers W, Song JJ, Haye M, Hruban RR, Kern SE, Fearon ER.
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| Genes Chromosomes Cancer 27(4):353-7. 2000
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| 24 | BCL2, DCC
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| Chromosome 18 breakpoint in t(11;18)(q21;q21) translocation associated with MALT lymphoma is proximal to BCL2 and distal to DCC.
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| Stoffel A, et al.
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| Genes Chromosomes Cancer 24 : 156-159. 1999
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| 25 | DCC
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| Loss of expression of the gene deleted in colon carcinoma (DCC) is closely related to histologic differentiation and lymph node metastasis in endometrial carcinoma.
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| Saegusa M, et al.
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| Cancer 85(2):453-64. 1999
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| 26 | NCOA3, DCC
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| Specific chromosomal aberrations and amplification of the AIB1 nuclear receptor coactivator gene in pancreatic carcinomas.
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| Ghadimi BM, et al.
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| Am J Pathol 154(2):525-36. 1999
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| 27 | DCC, NTN1, UNC5C
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| Attraction versus repulsion: modular receptors make the difference in axon guidance.
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| Seeger MA, Beattie CE.
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| Cell 97(7):821-4. Review. No abstract available 1999
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| 28 | DCC
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| The DCC gene product induces apoptosis by a mechanism requiring receptor proteolysis.
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| Mehlen P, et al.
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| Nature 395 : 801-804. 1998
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| 29 | DCC
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| DCC protein expression in hematopoietic cell populations and its relation to leukemogenesis.
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| Inokuchi K, et al.
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| J Clin Invest 97 : 852-857. 1996
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| 30 | LOH18CR1, DCC, SMAD4
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| Evaluation of candidate tumour suppressor genes on chromosome 18 in colorectal cancers.
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| Thiagalingam S, et al.
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| Nat Genet 13 : 343-346. 1996
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| 31 | DCC, TSG8A, TSG8B, LOH18CR1
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| Allelic loss on chromosomes 8p, 22q and 18q (DCC) in human prostate cancer.
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| Crundwell MC, et al.
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| Int J Cancer 69 : 295-300. 1996
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| 32 | DCC
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| UNC-40, a C. elegans homolog of DCC (Deleted in Colorectal Cancer), is required in motile cells responding to UNC-6 netrin cues.
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| Chan SSY, et al.
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| Cell 87 : 187-195. 1996
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| 33 | DCC
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| Deleted in colorectal cancer (DCC) encodes a netrin receptor.
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| Keino-Masu K, et al.
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| Cell 87 : 175-185. 1996
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| 34 | DCC, LOH18CR1
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| DCC expression is altered by multiple mechanisms in brain tumours.
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| Ekstrand BC, et al.
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| Oncogene 11 : 2393-2402. 1995
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| 35 | DCC
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| Cloning of the mouse homologue of the deleted in colorectal cancer gene (mDCC) and its expression in the developing mouse embryo.
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| Cooper HM, et al.
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| Oncogene 11 : 2243-2254. 1995
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| 36 | DCC
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| The DCC gene suppresses the malignant phenotype of transformed human epithelial cells.
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| Klingelhutz AJ, et al.
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| Oncogene 10 : 1581-1586. 1995
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| 37 | TSG9A, TSG17A, LOH18CR1, ST8, DCC
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| Consistent chromosome abnormalities in adenocarcinoma of the pancreas.
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| Griffin CA, et al.
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| Cancer Res 55 : 2394-2399. 1995
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| 38 | DCC
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| The DCC gene : structural analysis and mutations in colorectal carcinomas.
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| Cho KR, et al.
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| Genomics 19 : 525-531. 1994
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| 39 | DCC, LOH18CR1
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| Point mutations and allelic deletion of tumor suppressor gene DCC in human esophageal squamous cell carcinomas and their relation to metastasis.
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| Miyake S, et al.
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| Cancer Res 54 : 3007-3010. 1994
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| 40 | LOH18CR1, DCC
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| DCC gene alteration in human endometrial carcinomas.
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| Gima T, et al.
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| Int J Cancer 57 : 480-485. 1994
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| 41 | DCC
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| Frequent allelic deletions and loss of expression characterize the DCC gene in male germ cell tumors.
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| Murty VVVS, et al.
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| Oncogene 9 : 3227-3231. 1994
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| 42 | DCC, SERPINB2, DEL18QD
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| Molecular analysis of the 18q- syndrome--and correlation with phenotype.
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| Kline AD, et al.
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| Am J Hum Genet 52 : 895-906. 1993
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| 43 | DCC
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| Decreased expression of DCC mRNA in human colorectal cancers.
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| Itoh F, et al.
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| Int J Cancer 53 : 260-263. 1993
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| 44 | DCC, LOH18CR1
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| Frequent loss of expression and loss of heterozygosity of the putative tumor suppressor gene DCC in prostatic carcinomas.
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| Gao X, et al.
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| Cancer Res 53 : 2723-2727. 1993
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| 45 | DCC
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| SAM 1.1 and JOSH 4.4 : two RFLPs within the human DCC gene.
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| Simons JW, et al.
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| Hum Mol Genet 1 : 352. 1992
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| 46 | DCC
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| Dinucleotide repeat polymorphism in the human DCC gene at chromosome 18q21.
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| Risinger JI, et al.
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| Hum Mol Genet 1 : 657. 1992
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| 47 | DCC
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| HindIII polymorphism in the DCC gene.
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| Devilee P, et al.
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| Nucleic Acids Res 19 : 6965. 1991
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| 48 | LOH18CR1, DCC
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| Identification of a chromosome 18q gene that is altered in colorectal cancers.
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| Fearon ER, et al.
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| Science 247 : 49-56. 1990
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| 49 | BCL2, DCC
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| Malignant lymphoma of mucosa-associated lymphoid tissue.
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| Isaacson PG, et al.
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| Histopathology 11 : 445-462. 1987
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