Citations for
1CDC7, DBF4
Molecular mechanism of activation of human Cdc7 kinase: bipartite interaction with Dbf4/activator of S phase kinase (ASK) activation subunit stimulates ATP binding and substrate recognition.
Kitamura R, Fukatsu R, Kakusho N, Cho YS, Taniyama C, Yamazaki S, Toh GT, Yanagi K, Arai N, Chang HJ, Masai H.
J Biol Chem 286(26):23031-43. Epub 2011 May 2. 2011
2DBF4, PSIP1
Transcriptional co-activator LEDGF interacts with Cdc7-activator of S-phase kinase (ASK) and stimulates its enzymatic activity.
Hughes S, Jenkins V, Dar MJ, Engelman A, Cherepanov P.
J Biol Chem 285(1):541-54. Epub 2009 Oct 28. 2010
3CDC7, DBF4
Dbf4 regulates the Cdc5 Polo-like kinase through a distinct non-canonical binding interaction.
Chen YC, Weinreich M.
J Biol Chem 285(53):41244-54. Epub 2010 Oct 29. 2010
4CDC7, DBF4
Cdc7p-Dbf4p regulates mitotic exit by inhibiting Polo kinase.
Miller CT, Gabrielse C, Chen YC, Weinreich M.
PLoS Genet 5(5):e1000498. Epub 2009 May 29. 2009
5DBF4
Asymmetric bidirectional replication at the human DBF4 origin.
Romero J, Lee H.
Nat Struct Mol Biol 15(7):722-9. Epub 2008 Jun 8. 2008
6CDC7, DBF4, MCM2
Inhibition of Cdc7/Dbf4 kinase activity affects specific phosphorylation sites on MCM2 in cancer cells.
Charych DH, Coyne M, Yabannavar A, Narberes J, Chow S, Wallroth M, Shafer C, Walter AO.
J Cell Biochem 104(3):1075-86. 2008
7ADAMTS6, AURKB, CCNB1, CENPE, CRMP1, DBF4, DCLK3, PTTG1
A diagnostic marker set for invasion, proliferation, and aggressiveness of prolactin pituitary tumors.
Wierinckx A, Auger C, Devauchelle P, Reynaud A, Chevallier P, Jan M, Perrin G, Fèvre-Montange M, Rey C, Figarella-Branger D, Raverot G, Belin MF, Lachuer J, Trouillas J.
Endocr Relat Cancer 14(3):887-900.PMID: 17914117 2007
8DBF4
Human Dbf4/ASK promoter is activated through the Sp1 and MluI cell-cycle box (MCB) transcription elements.
Wu X, Lee H.
Oncogene 21(51):7786-96. 2002
9DBF4
Identification, characterization and chromosomal localization of the cognate human and murine DBF4 genes.
Lepke M, Putter V, Staib C, Kneissl M, Berger C, Hoehn K, Nanda I, Schmid M, Grummt F.
Mol Gen Genet 262(2):220-9 1999
10DBF4
A novel growth- and cell cycle-regulated protein, ASK, activates human Cdc7-related kinase and is essential for G1/S transition in mammalian cells.
Kumagai H, Sato N, Yamada M, Mahony D, Seghezzi W, Lees E, Arai K, Masai H.
Mol Cell Biol 19(7):5083-95. 1999