| 1 | DAPK1, DDX20
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| Death-associated protein kinase 1 suppresses hepatocellular carcinoma cell migration and invasion by upregulation of DEAD-box helicase 20.
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| Huang Y, Wang C, Li K, Ye Y, Shen A, Guo L, Chen P, Meng C, Wang Q, Yang X, Huang Z, Xing X, Lin Y, Liu X, Peng J, Lin Y.
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| Cancer Sci. Aug;111(8):2803-2813. doi: 10.1111/cas.14499. Epub 2020 Jun 26. 2020
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| 2 | DAPK1, ITPRIP
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| DANGER is involved in high glucose-induced radioresistance through inhibiting DAPK-mediated anoikis in non-small cell lung cancer.
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| Kwon T, Youn H, Son B, Kim D, Seong KM, Park S, Kim W, Youn B.
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| Oncotarget 7(6):7193-206. doi: 10.18632/oncotarget.6887.
2016
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| 3 | DAPK1, DAPK2
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| DAPK2 regulates oxidative stress in cancer cells by preserving mitochondrial function.
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| Schlegel CR, Georgiou ML, Misterek MB, Stöcker S, Chater ER, Munro CE, Pardo OE, Seckl MJ, Costa-Pereira AP.
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| Cell Death Dis 6:e1671. doi: 10.1038/cddis.2015.31.
2015
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| 4 | ATF6, CEBPB, DAPK1
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| Regulation of the death-associated protein kinase 1 expression and autophagy via ATF6 requires apoptosis signal-regulating kinase 1.
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| Gade P, Manjegowda SB, Nallar SC, Maachani UB, Cross AS, Kalvakolanu DV.
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| Mol Cell Biol 34(21):4033-48. doi: 10.1128/MCB.00397-14. Epub 2014 Aug 18.
2014
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| 5 | DAPK1, DAPK2, DAPK3
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| DAPK2 positively regulates motility of neutrophils and eosinophils in response to intermediary chemoattractants.
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| Geering B, Stoeckle C, Rozman S, Oberson K, Benarafa C, Simon HU.
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| J Leukoc Biol 95(2):293-303. doi: 10.1189/jlb.0813462. Epub 2013 Oct 25.
2014
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| 6 | DAPK1, DAPK2
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| Structure of the Dimeric Autoinhibited Conformation of DAPK2, a Pro-Apoptotic Protein Kinase.
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| Patel AK, Yadav RP, Majava V, Kursula I, Kursula P.
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| J Mol Biol 409(3):369-83. Epub 2011 Apr 8.
2011
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| 7 | DAPK1, PIN1
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| Death-associated protein kinase 1 phosphorylates Pin1 and inhibits its prolyl isomerase activity and cellular function.
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| Lee TH, Chen CH, Suizu F, Huang P, Schiene-Fischer C, Daum S, Zhang YJ, Goate A, Chen RH, Zhou XZ, Lu KP.
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| Mol Cell 42(2):147-59. Epub 2011 Apr 14.
2011
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| 8 | DAPK1, DAPK2
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| DAPK activates MARK1/2 to regulate microtubule assembly, neuronal differentiation, and tau toxicity.
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| Wu PR, Tsai PI, Chen GC, Chou HJ, Huang YP, Chen YH, Lin MY, Kimchi A, Chien CT, Chen RH.
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| Cell Death Differ ell Death Differ. 2011 Feb 11. [Epub ahead of print]
2011
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| 9 | DAPK1
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| GTP binding to the ROC domain of DAP-kinase regulates its function through intramolecular signalling.
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| Carlessi R, Levin-Salomon V, Ciprut S, Bialik S, Berissi H, Albeck S, Peleg Y, Kimchi A.
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| EMBO Rep 12(9):917-23. doi: 10.1038/embor.2011.126.
2011
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| 10 | DAPK1, GRIN2B
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| DAPK1 Interaction with NMDA Receptor NR2B Subunits Mediates Brain Damage in Stroke.
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| Tu W, Xu X, Peng L, Zhong X, Zhang W, Soundarapandian MM, Balel C, Wang M, Jia N, Zhang W, Lew F, Chan SL, Chen Y, Lu Y.
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| Cell 140(2):222-234.PMID: 20141836 2010
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| 11 | CUL3, DAPK1, KLHL20, RBX1
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| The Cullin 3 substrate adaptor KLHL20 mediates DAPK ubiquitination to control interferon responses.
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| Lee YR, Yuan WC, Ho HC, Chen CH, Shih HM, Chen RH.
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| EMBO J 29(10):1748-61. Epub 2010 Apr 13. 2010
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| 12 | DAPK1, PPP2CA, UNC5B
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| The dependence receptor UNC5H2/B triggers apoptosis via PP2A-mediated dephosphorylation of DAP kinase.
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| Guenebeaud C, Goldschneider D, Castets M, Guix C, Chazot G, Delloye-Bourgeois C, Eisenberg-Lerner A, Shohat G, Zhang M, Laudet V, Kimchi A, Bernet A, Mehlen P.
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| Mol Cell 40(6):863-76.
2010
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| 13 | DAPK1, ITPRIP
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| Death-associated protein kinase-mediated cell death modulated by interaction with DANGER.
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| Kang BN, Ahmad AS, Saleem S, Patterson RL, Hester L, Doré S, Snyder SH.
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| J Neurosci 30(1):93-8. doi: 10.1523/JNEUROSCI.3974-09.2010.
2010
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| 14 | BECN1, DAPK1
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| DAP-kinase-mediated phosphorylation on the BH3 domain of beclin 1 promotes dissociation of beclin 1 from Bcl-XL and induction of autophagy.
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| Zalckvar E, Berissi H, Mizrachy L, Idelchuk Y, Koren I, Eisenstein M, Sabanay H, Pinkas-Kramarski R, Kimchi A.
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| EMBO Rep 10(3):285-92. Epub 2009 Jan 30.
2009
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| 15 | DAPK1
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| Aberrant methylation of the death-associated protein kinase 1 (DAPK1) CpG island in chronic myeloid leukemia.
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| Qian J, Wang YL, Lin J, Yao DM, Xu WR, Wu CY.
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| Eur J Haematol 82(2):119-23. Epub 2008 Nov 6.
2009
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| 16 | CEBPB, DAPK1
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| Critical role for transcription factor C/EBP-beta in regulating the expression of death-associated protein kinase 1.
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| Gade P, Roy SK, Li H, Nallar SC, Kalvakolanu DV.
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| Mol Cell Biol 28(8):2528-48. Epub 2008 Feb 4.
2008
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| 17 | DAPK1, NEO1, RGMA, RGMB
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| Neogenin regulates neuronal survival through DAP kinase.
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| Fujita Y, Taniguchi J, Uchikawa M, Endo M, Hata K, Kubo T, Mueller BK, Yamashita T.
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| Cell Death Differ 15(10):1593-608. Epub 2008 Jun 27.PMID: 18583991 2008
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| 18 | DAPK1
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| DAP kinase mediates the phosphorylation of tropomyosin-1 downstream of the ERK pathway, which regulates the formation of stress fibers in response to oxidative stress.
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| Houle F, Poirier A, Dumaresq J, Huot J.
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| J Cell Sci 120(Pt 20):3666-77. Epub 2007 Sep 25.
2007
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| 19 | DAPK1
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| Downregulation of death-associated protein kinase 1 (DAPK1) in chronic lymphocytic leukemia.
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| Raval A, Tanner SM, Byrd JC, Angerman EB, Perko JD, Chen SS, Hackanson B, Grever MR, Lucas DM, Matkovic JJ, Lin TS, Kipps TJ, Murray F, Weisenburger D, Sanger W, Lynch J, Watson P, Jansen M, Yoshinaga Y, Rosenquist R, de Jong PJ, Coggill P, Beck S, Lynch H, de la Chapelle A, Plass C.
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| Cell 129(5):879-90.
2007
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| 20 | DAPK1
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| Regulation of death-associated protein kinase. Stabilization by HSP90 heterocomplexes.
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| Zhang L, Nephew KP, Gallagher PJ.
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| J Biol Chem 282(16):11795-804. Epub 2007 Feb 26.
2007
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| 21 | CDKN2A,DAPK1,GSRP1
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| The power and the promise of DNA methylation markers.
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| Laird PW.
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| Nat Rev Cancer 3(4):253-66. Review. 2003
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| 22 | DAPK1
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| DAP-kinase induces apoptosis by suppressing integrin activity and disrupting matrix survival signals.
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| Wang WJ, Kuo JC, Yao CC, Chen RH.
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| J Cell Biol 159(1):169-79. 2002
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| 23 | DAPK1
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| Patterns of gene promoter methylation in squamous cell cancer of the head and neck.
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| Hasegawa M, Nelson HH, Peters E, Ringstrom E, Posner M, Kelsey KT.
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| Oncogene 21(27):4231-6. 2002
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| 24 | DAPK1
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| The pro-apoptotic function of death-associated protein kinase is controlled by a unique inhibitory autophosphorylation-based mechanism.
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| Shohat G, Spivak-Kroizman T, Cohen O, Bialik S, Shani G, Berrisi H, Eisenstein M, Kimchi A.
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| J Biol Chem 276(50):47460-7. Epub 2001 Sep 28.
2001
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| 25 | CTSD, DAP, DAP3, DAPK1, EIF4G2
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| Death associated proteins (DAPs): from gene identification to the analysis of their apoptotic and tumor suppressive functions.
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| Levy-Strumpf N, et al.
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| Oncogene 17(25):3331-40. Review. 1998
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| 26 | DAPK1
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| DAP-kinase is a Ca2+/calmodulin-dependent, cytoskeletal-associated protein kinase, with cell death-inducing functions that depend on its catalytic activity.
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| Cohen O, et al.
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| EMBO J 16 : 998-1008. 1997
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| 27 | DAP, DAPK1
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| Assignment of DAP1 and DAPK-genes that positively mediate programmed cell death triggered by IFN-gamma-to chromosome regions 5p12.2 and 9q34.1, respectively.
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| Feinstein E, et al.
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| Genomics 29 : 305-307. 1995
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| 28 | DAPK1
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| Identification of a novel serine/threonine kinase and a novel 15-kD protein as potential mediators of the gamma interferon-induced cell death.
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| Deiss LP, Feinstein E, Berissi H, Cohen O, Kimchi A.
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| Genes Dev 9(1):15-30. 1995
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