1 | DAP3, PRLTS7
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| Bi-allelic variants in DAP3 result in reduced assembly of the mitoribosomal small subunit with altered apoptosis and a Perrault-syndrome-spectrum phenotype
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| Smith TB, Kopajtich R, Demain LAM, Rea A, Thomas HB, Schiff M, Beetz C, Joss S, Conway GS, Shukla A, Yeole M, Radhakrishnan P, Azzouz H, Ben Chehida A, Elmaleh-Bergès M, Glasgow RIC, Thompson K, Oláhová M, He L, Jenkinson EM, Jahic A, Belyantseva IA, Barzik M, Urquhart JE, O'Sullivan J, Williams SG, Bhaskar SS, Carrera S, Blakes AJM, Banka S, Yue WW, Ellingford JM, Houlden H; DDD Study; Munro KJ, Friedman TB, Taylor RW, Prokisch H, O'Keefe RT, Newman WG.
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| Am J Hum Genet. Jan 2;112(1):59-74. doi: 10.1016/j.ajhg.2024.11.007. Epub 2024 Dec 18. 2025
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2 | DAP3
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| Identification of DAP3 as candidate prognosis marker and potential therapeutic target for hepatocellular carcinoma
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| Yuan LX, Yue ZQ, Ma QR, Zhang P, Xiao F, Chen L.
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| Front Immunol. Feb 20;16:1528853. doi: 10.3389/fimmu.2025.1528853. 2025
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3 | DAP3
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| Multilayered control of splicing regulatory networks by DAP3 leads to widespread alternative splicing changes in cancer.
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| Han J, An O, Ren X, Song Y, Tang SJ, Shen H, Ke X, Ng VHE, Tay DJT, Tan HQ, Kappei D, Yang H, Chen L.
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| Nat Commun. Apr 4;13(1):1793. doi: 10.1038/s41467-022-29400-7. 2022
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4 | DAP1, DAP3
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| Expression of Death Associated Proteins DAP1 and DAP3 in Human Pancreatic Cancer.
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| Sui L, Ye L, Sanders AJ, Yang Y, Hao C, Hargest R, Jiang WG.
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| Anticancer Res. May;41(5):2357-2362. doi: 10.21873/anticanres.15010. 2021
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5 | ADARB1, DAP3
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| Suppression of adenosine-to-inosine (A-to-I) RNA editome by death associated protein 3 (DAP3) promotes cancer progression.
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| Han J, An O, Hong H, Chan THM, Song Y, Shen H, Tang SJ, Lin JS, Ng VHE, Tay DJT, Molias FB, Pitcheshwar P, Tan HQ, Yang H, Chen L
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| Sci Adv. Jun 17;6(25):eaba5136. doi: 10.1126/sciadv.aba5136. 2020
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6 | DAP3
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| Death-associated Protein 3 Regulates Mitochondrial-encoded Protein Synthesis and Mitochondrial Dynamics.
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| Xiao L, Xian H, Lee KY, Xiao B, Wang H, Yu F, Shen HM, Liou YC.
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| J Biol Chem. Oct 9;290(41):24961-74. doi: 10.1074/jbc.M115.673343. Epub 2015 Aug 25. 2015
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7 | DAP3
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| The role of death-associated protein 3 in apoptosis, anoikis and human cancer.
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| Wazir U, Orakzai MM, Khanzada ZS, Jiang WG, Sharma AK, Kasem A, Mokbel K.
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| Cancer Cell Int. Apr 10;15:39. doi: 10.1186/s12935-015-0187-z. 2015
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8 | DAP3
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| The mRNA expression of DAP3 in human breast cancer: correlation with clinicopathological parameters.
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| Wazir U, Jiang WG, Sharma AK, Mokbel K.
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| Anticancer Res. Feb;32(2):671-4. 2012
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9 | DAP3
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| Identification of DELE, a novel DAP3-binding protein which is crucial for death receptor-mediated apoptosis induction.
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| Harada T, Iwai A, Miyazaki T.
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| Apoptosis poptosis. 2010 Jun 19. [Epub ahead of print]PMID: 20563667 2010
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10 | DAP3, NR4A1
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| Critical function of death-associated protein 3 in T cell receptor-mediated apoptosis induction.
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| Tosa N, Iwai A, Tanaka T, Kumagai T, Nitta T, Chiba S, Maeda M, Takahama Y, Uede T, Miyazaki T.
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| Biochem Biophys Res Commun 395(3):356-60. Epub 2010 Apr 8.PMID: 20381457 2010
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11 | DAP3, MAVS
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| IPS-1 is crucial for DAP3-mediated anoikis induction by caspase-8 activation.
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| Li HM, Fujikura D, Harada T, Uehara J, Kawai T, Akira S, Reed JC, Iwai A, Miyazaki T.
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| Cell Death Differ 16(12):1615-21. Epub 2009 Jul 31.PMID: 19644511 2009
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12 | DAP3
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| Death-associated protein 3 is overexpressed in human thyroid oncocytic tumours.
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| Jacques C, Fontaine JF, Franc B, Mirebeau-Prunier D, Triau S, Savagner F, Malthiery Y.
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| Br J Cancer 101(1):132-8. Epub 2009 Jun 16.PMID: 19536094 2009
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13 | DAP3
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| Identification of phosphorylation sites in mammalian mitochondrial ribosomal protein DAP3.
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| Miller JL, Koc H, Koc EC.
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| Protein Sci 17(2):251-60.PMID: 18227431 2008
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14 | DAP3
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| Death-associated protein 3 regulates cellular senescence through oxidative stress response.
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| Murata Y, Wakoh T, Uekawa N, Sugimoto M, Asai A, Miyazaki T, Maruyama M.
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| FEBS Lett 580(26):6093-9. Epub 2006 Oct 12.PMID: 17056041 2006
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15 | DAP3
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| Functional role of death-associated protein 3 (DAP3) in anoikis.
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| Miyazaki T, Shen M, Fujikura D, Tosa N, Kim HR, Kon S, Uede T, Reed JC.
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| J Biol Chem 279(43):44667-72. Epub 2004 Aug 9.PMID: 15302871 2004
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16 | DAP3, TNFSF10, DAPK3
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| TRAIL-induced apoptosis is independent of the mitochondrial apoptosis mediator DAP3.
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| Berger T, Kretzler M.
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| Biochem Biophys Res Commun 297(4):880-4. 2002
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17 | DAP3, NR3C1
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| Functional interaction between the pro-apoptotic DAP3 and the glucocorticoid receptor.
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| Hulkko SM, Zilliacus J.
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| Biochem Biophys Res Commun 295(3):749-55. 2002
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18 | DAP3
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| A conserved N-terminal sequence targets human DAP3 to mitochondria.
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| Morgan CJ, Jacques C, Savagner F, Tourmen Y, Mirebeau DP, Malthiery Y, Reynier P.
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| Biochem Biophys Res Commun 280(1):177-81. 2001
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19 | DAP3, MRPS30
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| A new face on apoptosis: death-associated protein 3 and PDCD9 are mitochondrial ribosomal proteins.
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| Cavdar Koc E, Ranasinghe A, Burkhart W, Blackburn K, Koc H, Moseley A, Spremulli LL.
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| FEBS Lett 492(1-2):166-70. 2001
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20 | MRP63, MRPL51, MRPL10, MRPL11, MRPL12, MRPL13, MRPL14, MRPL16, MRPL17, MRPL19, MRPL2, MRPL20, MRPL24, MRPL27, MRPL3, MRPL30, MRPL32, MRPL33, MRPL34, MRPL36, MRPL38, MRPL39, MRPL4, MRPL40, MRPL41, MRPL43, MRPL9, MRPS11, MRPS11P1, MRPS14, MRPS15, MRPS16, MRPS18A, MRPS2, MRPS21, MRPS22, MRPS23, MRPS24, MRPS25, MRPS26, MRPS5, MRPS6, MRPS7, IMP3, IMP4, MRPL1, MRPL15, MRPL22, MRPL23, MRPL37, MRPL42, MRPS12, MRPS17, MRPS28, DAP3, MRPS30, MRPL51
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| The human mitochondrial ribosomal protein genes: mapping of 54 genes to the chromosomes and implications for human disorders.
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| Kenmochi N, Suzuki T, Uechi T, Magoori M, Kuniba M, Higa S, Watanabe K,Tanaka T.
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| Genomics 77(1-2):65-70. 2001
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21 | DAP3
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| Structure-function analysis of an evolutionary conserved protein, DAP3, which mediates TNF-alpha- and Fas-induced cell death.
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| Kissil JL, et al.
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| EMBO J 18 : 353-362. 1999
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22 | CTSD, DAP, DAP3, DAPK1, EIF4G2
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| Death associated proteins (DAPs): from gene identification to the analysis of their apoptotic and tumor suppressive functions.
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| Levy-Strumpf N, et al.
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| Oncogene 17(25):3331-40. Review. 1998
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23 | DAP3
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| Assignment of death associated protein 3 (DAP3) to human chromosome 1q21 by in situ hybridization.
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| Kissil JL, Kimchi A.
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| Cytogenet Cell Genet 77(3-4):252. 1997
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24 | DAP3
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| Isolation of DAP3, a novel mediator of interferon-gamma-induced cell death.
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| Kissil JL, et al.
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| J Biol Chem 270 : 27932-27936. 1995
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