1 | DACT3, DVL2
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| Disruption of the Dapper3 gene aggravates ureteral obstruction-mediated renal fibrosis by amplifying Wnt/β-catenin signaling.
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| Xue H, Xiao Z, Zhang J, Wen J, Wang Y, Chang Z, Zhao J, Gao X, Du J, Chen YG.
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| J Biol Chem 288(21):15006-14. doi: 10.1074/jbc.M113.458448. Epub 2013 Apr 11.
2013
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2 | DACT1, DACT2, DACT3
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| All Dact (Dapper/Frodo) scaffold proteins dimerize and exhibit conserved interactions with Vangl, Dvl, and serine/threonine kinases.
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| Kivimäe S, Yang XY, Cheyette BN.
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| BMC Biochem 12:33.
2011
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3 | DACT1, DACT2, DACT3
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| Dact1-3 mRNAs exhibit distinct expression domains during tooth development.
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| Kettunen P, Kivimäe S, Keshari P, Klein OD, Cheyette BN, Luukko K.
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| Gene Expr Patterns 10(2-3):140-3. Epub 2010 Feb 17.PMID: 20170752 2010
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4 | DACT3
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| DACT3 is an epigenetic regulator of Wnt/beta-catenin signaling in colorectal cancer and is a therapeutic target of histone modifications.
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| Jiang X, Tan J, Li J, Kivimäe S, Yang X, Zhuang L, Lee PL, Chan MT, Stanton LW, Liu ET, Cheyette BN, Yu Q.
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| Cancer Cell 13(6):529-41.
2008
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5 | DACT1, DACT2, DACT3
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| Dapper1 is a nucleocytoplasmic shuttling protein that negatively modulates Wnt signaling in the nucleus.
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| Gao X, Wen J, Zhang L, Li X, Ning Y, Meng A, Chen YG.
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| J Biol Chem 283(51):35679-88. Epub 2008 Oct 20.
2008
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6 | DACT2, DACT3
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| Three Dact gene family members are expressed during embryonic development and in the adult brains of mice.
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| Fisher DA, Kivimäe S, Hoshino J, Suriben R, Martin PM, Baxter N, Cheyette BN.
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| Dev Dyn 235(9):2620-30. 2006
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7 | DACT1, DACT2, DACT3
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| Three Dact gene family members are expressed during embryonic development and in the adult brains of mice.
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| Fisher DA, Kivimäe S, Hoshino J, Suriben R, Martin PM, Baxter N, Cheyette BN.
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| Dev Dyn 235(9):2620-30.PMID: 16881060 2006
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8 | DACT1, DACT2, DACT3
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| Dapper, a Dishevelled-associated antagonist of beta-catenin and JNK signaling, is required for notochord formation.
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| Cheyette BN, Waxman JS, Miller JR, Takemaru K, Sheldahl LC, Khlebtsova N, Fox EP, Earnest T, Moon RT.
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| Dev Cell 2(4):449-61.
2002
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