| 1 | CYP2R1
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| Low-Frequency Synonymous Coding Variation in CYP2R1 Has Large Effects on Vitamin D Levels and Risk of Multiple Sclerosis.
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| Manousaki D, Dudding T, Haworth S, Hsu YH, Liu CT, Medina-Gómez C, Voortman T, van der Velde N, Melhus H, Robinson-Cohen C, Cousminer DL, Nethander M, Vandenput L, Noordam R, Forgetta V, Greenwood CMT, Biggs ML, Psaty BM, Rotter JI, Zemel BS, Mitchell JA, Taylor B, Lorentzon M, Karlsson M, Jaddoe VVW, Tiemeier H, Campos-Obando N, Franco OH, Utterlinden AG, Broer L, van Schoor NM, Ham AC, Ikram MA, Karasik D, de Mutsert R, Rosendaal FR, den Heijer M, Wang TJ, Lind L, Orwoll ES, Mook-Kanamori DO, Michaëlsson K, Kestenbaum B, Ohlsson C, Mellström D, de Groot LCPGM, Grant SFA, Kiel DP, Zillikens MC, Rivadeneira F, Sawcer S, Timpson NJ, Richards JB.
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| Am J Hum Genet 101(2):227-238. doi: 10.1016/j.ajhg.2017.06.014. Epub 2017 Jul 27.
2017
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| 2 | CYP2R1, GC
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| Genetic Variation in CYP2R1 and GC Genes Associated With Vitamin D Deficiency Status.
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| Slater NA, Rager ML, Havrda DE, Harralson AF.
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| J Pharm Pract 30(1):31-36. doi: 10.1177/0897190015585876. Epub 2016 Jul 9.
2017
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| 3 | CYP27A1, CYP2R1
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| Role of local bioactivation of vitamin D by CYP27A1 and CYP2R1 in the control of cell growth in normal endometrium and endometrial carcinoma.
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| Bergadà L, Pallares J, Vittoria Arcidiacono M, Cardus A, Santacana M, Valls J, Cao G, Fernàndez E, Dolcet X, Dusso AS, Matias-Guiu X.
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| Lab Invest ab Invest. 2014 Apr 14. doi: 10.1038/labinvest.2014.57. [Epub ahead of print] 2014
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| 4 | CYP247B1, CYP24A1, CYP2R1
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| Vitamin D hydroxylases CYP2R1, CYP27B1 and CYP24A1 in renal cell carcinoma.
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| Urbschat A, Paulus P, von Quernheim QF, Brück P, Badenhoop K, Zeuzem S, Ramos-Lopez E.
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| Eur J Clin Invest 43(12):1282-90. doi: 10.1111/eci.12176. Epub 2013 Oct 12.
2013
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| 5 | CYP24A1, CYP2R1
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| DNA methylation levels of CYP2R1 and CYP24A1 predict vitamin D response variation.
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| Zhou Y, Zhao LJ, Xu X, Ye A, Travers-Gustafson D, Zhou B, Wang HW, Zhang W, Lee Hamm L, Deng HW, Recker RR, Lappe JM.
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| J Steroid Biochem Mol Biol Steroid Biochem Mol Biol. 2013 Oct 12. pii: S0960-0760(13)00197-0. doi: 10.1016/j.jsbmb.2013.10.004. [Epub ahead of print]
2013
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| 6 | CYP2R1
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| CYP2R1 is a major, but not exclusive, contributor to 25-hydroxyvitamin D production in vivo.
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| Zhu JG, Ochalek JT, Kaufmann M, Jones G, Deluca HF.
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| Proc Natl Acad Sci U S A 110(39):15650-5. doi: 10.1073/pnas.1315006110. Epub 2013 Sep 9.
2013
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| 7 | CYP2R1
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| Altered bone status in unilateral testicular cancer survivors: Role of CYP2R1 and its luteinizing hormone-dependency.
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| Foresta C, Selice R, De Toni L, Di Mambro A, Carraro U, Plebani M, Garolla A.
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| J Endocrinol Invest 36(6):379-84. doi: 10.3275/8650. Epub 2012 Oct 9.
2013
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| 8 | CYP27A1, CYP2R1
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| Vitamin D 25-hydroxylase - Four decades of searching, are we there yet?
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| Zhu J, DeLuca HF.
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| Arch Biochem Biophys 523(1):30-6. doi: 10.1016/j.abb.2012.01.013. Epub 2012 Jan 31. Review.
2012
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| 9 | CYP2R1
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| Bone mineral density and testicular failure: evidence for a role of vitamin D 25-hydroxylase in human testis.
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| Foresta C, Strapazzon G, De Toni L, Perilli L, Di Mambro A, Muciaccia B, Sartori L, Selice R.
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| J Clin Endocrinol Metab 96(4):E646-52. doi: 10.1210/jc.2010-1628. Epub 2011 Jan 26.
2011
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| 10 | CYP2R1, VDHR
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| Structural analysis of CYP2R1 in complex with vitamin D3.
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| Strushkevich N, Usanov SA, Plotnikov AN, Jones G, Park HW.
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| J Mol Biol 380(1):95-106. doi: 10.1016/j.jmb.2008.03.065. Epub 2008 Apr 8.
2008
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| 11 | CYP2R1
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| CYP2R1 (vitamin D 25-hydroxylase) gene is associated with susceptibility to type 1 diabetes and vitamin D levels in Germans.
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| Ramos-Lopez E, Brück P, Jansen T, Herwig J, Badenhoop K.
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| Diabetes Metab Res Rev 23(8):631-6.
2007
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| 12 | CYP1B1, CYP1A1, CYP2U1, CYP2E1, CYP2W1, CYP4B1, CYP4X1, CYP2R1
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| Expression patterns of mouse and human CYP orthologs (families 1-4) during development and in different adult tissues.
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| Choudhary D, Jansson I, Stoilov I, Sarfarazi M, Schenkman JB.
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| Arch Biochem Biophys 436(1):50-61. 2005
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| 13 | CYP2R1, VDHR
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| Genetic evidence that the human CYP2R1 enzyme is a key vitamin D 25-hydroxylase.
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| Cheng JB, Levine MA, Bell NH, Mangelsdorf DJ, Russell DW.
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| Proc Natl Acad Sci U S A 101(20):7711-5. Epub 2004 May 05. 2004
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| 14 | CYP2R1
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| De-orphanization of cytochrome P450 2R1: a microsomal vitamin D 25-hydroxilase.
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| Cheng JB, Motola DL, Mangelsdorf DJ, Russell DW.
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| J Biol Chem 278(39):38084-93. Epub 2003 Jul 16. 2003
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