| 1 | CYP2D6
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| Identification of genetic variants of human cytochrome P450 2D6 with impaired mitochondrial targeting.
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| Sangar MC, Anandatheerthavarada HK, Martin MV, Guengerich FP, Avadhani NG.
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| Mol Genet Metab 99(1):90-7. Epub .PMID: 19781968 2010
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| 2 | CYP2D6, CYP2D6DM
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| CYP2D6 polymorphism in relation to tramadol metabolism: a study of faroese patients.
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| Halling J, Weihe P, Brosen K.
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| Ther Drug Monit 30(3):271-5. 2008
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| 3 | CYP2D6, CYP2E1, GSTM1
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| Role of CYP2D6, CYP1A1, CYP2E1, GSTT1, and GSTM1 genes in the susceptibility to acute leukemias.
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| Aydin-Sayitoglu M, Hatirnaz O, Erensoy N, Ozbek U.
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| Am J Hematol 81(3):162-70. 2006
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| 4 | CYP2D6, CYP2D6DM, CYP2D7P1
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| A frameshift mutation and alternate splicing in human brain generate a functional form of the pseudogene cytochrome P4502D7 that demethylates codeine to morphine.
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| Pai HV, Kommaddi RP, Chinta SJ, Mori T, Boyd MR, Ravindranath V.
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| J Biol Chem 279(26):27383-9. Epub 2004 Mar 29. 2004
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| 5 | CYP2D6
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| Polymorphisms of the CYP2D6 gene increase susceptibility to ankylosing spondylitis.
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| Brown MA, Edwards S, Hoyle E, Campbell S, Laval S, Daly AK, Pile KD, Calin A, Ebringer A, Weeks DE, Wordsworth BP.
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| Hum Mol Genet 9(11):1563-6. 2000
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| 6 | CYP2D6, NAGA, SREBF2, TSG22C
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| Refinement of an ovarian cancer tumour suppressor gene locus on chromosome arm 22q and mutation analysis of CYP2D6, SREBP2 and NAGA.
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| Bryan EJ, Thomas NA, Palmer K, Dawson E, Englefield P, Campbell IG.
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| Int J Cancer 87(6):798-802. 2000
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| 7 | CYP2D6, GSTM1, NAT2
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| Genetic polymorphism of CYP2D6, GSTM1 and NAT2 and susceptibility to haematological neoplasias.
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| Lemos MC, et al.
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| Carcinogenesis 20(7):1225-9 1999
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| 8 | CYP2D6
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| Mutation involving cytochrome P450IID6 in two Japanese patients with neuroleptic malignant syndrome.
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| Kawanishi C, Shimoda Y, Fujimaki J, Onishi H, Suzuki K, Hanihara T, Sugiyama N, Kosaka K.
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| J Neurol Sci 160 : 102-104. 1998
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| 9 | CYP24A1, CYP26A1, CYP27A1, CYP27B1, CYP2A, CYP2@, CYP2A13, CYP2A6, CYP2A7, CYP2A7P1, CYP2B, CYP2B6, CYP2B7P1, CYP2C@, CYP2C18, CYP2C19, CYP2C8, CYP2C9, CYP2D@, CYP2D6, CYP2D7P1, CYP2D7P2, CYP2D8P1, CYP2D8P2, CYP2E1, CYP2F1, CYP2F1P, CYP2G1P, CYP2G2P, CYP2J2, CYP2S1, CYP2T2P, CYP2T3P
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| Molecular genetics of the human cytochrome P450 monooxygenase superfamily.
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| Smith G, Stubbins MJ, Harries LW, Wolf CR.
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| Xenobiotica 28(12):1129-65. Review. No abstract available. 1998
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| 10 | CYP2D6
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| An inactive cytochrome P450 CYP2D6 allele containing a deletion and a base substitution.
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| Daly AK, et al.
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| Hum Genet 95 : 337-341. 1995
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| 11 | CYP2D6
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| A nonsense mutation in the cytochrome P450 CYP2D6 gene identified in a Caucasian with an enzyme deficiency.
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| Broly F, et al.
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| Hum Genet 96 : 601-603 1995
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| 12 | CYP2D6
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| Homologous unequal cross-over involving a 2.8 kb direct repeat as a mechanism for the generation of allelic variants of the human cytochrome P450 CYP2D6 gene.
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| Steen VM, et al.
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| Hum Mol Genet 4 : 2251-2257. 1995
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| 13 | CYP2D6
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| A BamHI polymorphism in the human cytochrome P450 gene, CYP2D6.
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| Morimoto Y, et al.
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| Clin Genet 47 : 103-104. 1995
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| 14 | CYP2D6, CYP2D6DM
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| Identification of a new variant CYP2D6 allele with a single base deletion in exon 3 and its association with the poor metabolizer phenotype.
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| Saxena R, Shaw GL, Relling MV, Frame JN, Moir DT, Evans WE, Caporaso N, Weiffenbach B.
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| Hum Mol Genet 3 : 923-926. 1994
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| 15 | CYP2D6, CYP2D6DM
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| DNA haplotype-dependent differences in the amino acid sequence of debrisoquine 4-hydroxylase (CYP2D6) : evidence for two major allozymes in extensive metabolisers.
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| Panserat S, et al.
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| Hum Genet 94 : 401-406. 1994
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| 16 | CYP2D6
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| Localization of the CYP2D gene locus to human chromosome 22q13.1 by polymerase chain reaction, in situ hybridization, and linkage analysis.
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| Gough AC, et al.
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| Genomics 15 : 430-432. 1993
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| 17 | CYP2D6
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| Inherited amplification of an active gene in the cytochrome P450 CYP2D locus as a cause of ultrarapid metabolism of debrisoquine.
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| Johansson I, et al.
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| Proc Natl Acad Sci U S A 90 : 11825-11829. 1993
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| 18 | CYP2D6
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| A novel cytochrome P-450IID6 mutant gene associated with Parkinson's disease.
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| Tsuneoka Y, et al.
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| J Biochem (Tokyo) 114 : 263-266. 1993
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| 19 | CYP2D6
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| DNA haplotype dependency of debrisoquine 4-hydroxylase (CYP2D6) expression among extensive metabolisers.
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| Mura C, et al.
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| Hum Genet 92 : 367-372. 1993
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| 20 | CYP2D6
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| Debrisoquine hydroxylase gene polymorphism and susceptibility to Parkinson's disease.
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| Smith CAD, et al.
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| Lancet 339 : 1375-1377. 1992
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| 21 | CYP2D6
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| Relationship between the debrisoquine hydroxylase polymorphism and cancer susceptibility.
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| Wolf CR, et al.
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| Carcinogenesis 13 : 1035-1038. 1992
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| 22 | CYP2D6
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| Dinucleotide repeat polymorphism at the debrisoquine 4-hydroxylase (CYP2D) locus.
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| Trofatter JA, et al.
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| Nucleic Acids Res 19 : 2802. 1991
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| 23 | CYP2D6
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| Deletion of the entire cytochrome P450 CYP2D6 gene as a cause of impaired drug metabolism in poor metabolizers of the debrisoquine/sparteine polymorphism.
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| Gaedigk A, et al.
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| Am J Hum Genet 48 : 943-950. 1991
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| 24 | CYP2D6, CYP2D6DM
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| Debrisoquine/sparteine hydroxylation genotype and phenotype : analysis of common mutations and alleles of CYP2D6 in a european population.
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| Broly F, et al.
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| DNA Cell Biol 10 : 545-558. 1991
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| 25 | CYP2D6
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| NcoI RFLP in the pseudogene (CYP2D8P) of the human debrisoquine 4-hydroxylase locus.
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| Mura C, et al.
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| Nucleic Acids Res 19 : 1162. 1991
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| 26 | CYP2D6
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| Dinucleotide repeat polymorphism at the human debrisoquine 4-hydroxylase (CYP2D) locus.
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| Polymeropoulos MH, et al.
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| Nucleic Acids Res 19 : 1961. 1991
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| 27 | CYP2D6, CYP2D6DM
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| Genotyping of poor metabolisers of debrisoquine by allele-specific PCR amplification.
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| Heim M, et al.
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| Lancet 336 : 529-532. 1990
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| 28 | CYP2D6
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| Xba1 16-plus 9-kilobase DNA restriction fragments identify a mutant allele for debrisoquin hydroxylase: report of a family study.
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| Evans WE, et al.
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| Mol Pharmacol 37 : 639-642. 1990
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| 29 | CYP2D6, CYP2D6DM
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| Multiple mutations of the human cytochrome P450IID6 gene (CYP2D6) in poor metabolizers of debrisoquine. Study of the functional significance of individual mutations by expression of chimeric genes.
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| Kagimoto M, et al.
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| J Biol Chem 265 : 17209-17214. 1990
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| 30 | CYP2D6
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| Identification of the primary gene defect at the cytochrome P450 CYP2D locus.
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| Gough AC, et al.
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| Nature 347 : 773-776. 1990
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| 31 | CYP2D6, CYP2D6DM
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| The human CYP2D locus associated with a common genetic defect in drug oxidation: A G1934-A base change in intron 3 of a mutant CYP2D6 allele results in an aberrant 3' splice recognition site.
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| Hanioka N, et al.
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| Am J Hum Genet 47 : 994-1001. 1990
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| 32 | XRCC6, CYP2D6
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| Localization of TSHR gene and cytochrome p450 IID subfamily on chromosome 22 by linkage analysis.
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| Mitchell AL, et al.
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| (HGM10) Cytogenet Cell Genet 51 : 1045. 1989
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| 33 | CYP2D6, CYP2D8P2
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| The human debrisoquine 4-hydroxylase (CYP2D) locus : sequence and identification of the polymorphic CYP2D6 gene, a related gene, and a pseudogene.
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| Kimura S, et al.
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| Am J Hum Genet 45 : 889-904. 1989
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| 34 | CYP2D6, CYP2D6DM
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| Characterization of the common genetic defect in humans deficient in debrisoquine metabolism.
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| Gonzalez FJ, et al.
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| Nature 331 : 442-446. 1988
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| 35 | CYP2D6
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| Human debrisoquine 4-hydroxylase (P450IID1) : cDNA and deduced amino acid sequence and assignment of CYP2D locus to chromosome 22.
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| Gonzalez FJ, et al.
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| Genomics 2 : 174-179. 1988
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| 36 | CYP2D6
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| Chromosomal assignment of human cytochrome P-450 (debrisoquine/spartein type) to chromosome 22.
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| Eichelbaum M, et al.
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| (HGM9) Cytogenet Cell Genet 46 : 610. 1987
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