Citations for
1CYP2C9
Massively parallel characterization of CYP2C9 variant enzyme activity and abundance
Amorosi CJ, Chiasson MA, McDonald MG, Wong LH, Sitko KA, Boyle G, Kowalski JP, Rettie AE, Fowler DM, Dunham MJ.
Am J Hum Genet. Sep 2;108(9):1735-1751. doi: 10.1016/j.ajhg.2021.07.001. Epub 2021 Jul 26. 2021
2CYP2C9
Impact of CYP2C9-Interacting Drugs on Warfarin Pharmacogenomics.
Agrawal S, Heiss MS, Fenter RB, Abramova TV, Perera MA, Pacheco JA, Smith ME, Rasmussen-Torvik LJ, George AL Jr.
Clin Transl Sci. Sep;13(5):941-949. doi: 10.1111/cts.12781. Epub 2020 Apr 9. 2020
3CYP2C9
Estimation of Interindividual Variability of Pharmacokinetics of CYP2C9 Substrates in Humans
Chiba K, Shimizu K, Kato M, Miyazaki T, Nishibayashi T, Terada K, Sugiyama Y.
J Pharm Sci. Sep;106(9):2695-2703. doi: 10.1016/j.xphs.2017.04.021. Epub 2017 Apr 21. 2017
4CYP2C19, CYP2C8, CYP2C9
Genetic Polymorphisms and in Vitro Functional Characterization of CYP2C8, CYP2C9, and CYP2C19 Allelic Variants
Hiratsuka M.
Biol Pharm Bull. 39(11):1748-1759. doi: 10.1248/bpb.b16-00605. 2016
5CYP2C19, CYP2C9
Impact of genetic polymorphisms in CYP2C9 and CYP2C19 on the pharmacokinetics of clinically used drugs
Hirota T, Eguchi S, Ieiri I.
Drug Metab Pharmacokinet. 28(1):28-37. doi: 10.2133/dmpk.dmpk-12-rv-085. Epub 2012 Nov 20. 2013
6CYP2C9, VKORC1
Influence of CYP2C9 and VKORC1 on patient response to warfarin: a systematic review and meta-analysis.
Jorgensen AL, FitzGerald RJ, Oyee J, Pirmohamed M, Williamson PR.
PLoS One 7(8):e44064. doi: 10.1371/journal.pone.0044064. Epub 2012 Aug 29. Review. 2012
7CYP2C9, CYP4F2, VKORC1
A genome-wide association study confirms VKORC1, CYP2C9, and CYP4F2 as principal genetic determinants of warfarin dose.
Takeuchi F, McGinnis R, Bourgeois S, Barnes C, Eriksson N, Soranzo N, Whittaker P, Ranganath V, Kumanduri V, McLaren W, Holm L, Lindh J, Rane A, Wadelius M, Deloukas P.
PLoS Genet 5(3):e1000433. Epub 2009 Mar 20. 2009
8CYP2C9, VKORC1
Warfarin pharmacogenetics: CYP2C9 and VKORC1 genotypes predict different sensitivity and resistance frequencies in the Ashkenazi and Sephardi Jewish populations.
Scott SA, Edelmann L, Kornreich R, Desnick RJ.
Am J Hum Genet 82(2):495-500. Epub 2008 Jan 17. 2008
9CYP2C9, VKORC1
Polymorphisms in the VKORC1 gene are strongly associated with warfarin dosage requirements in patients receiving anticoagulation.
Li T, Lange LA, Li X, Susswein L, Bryant B, Malone R, Lange EM, Huang TY, Stafford DW, Evans JP.
J Med Genet 43(9):740-4. Epub 2006 Apr 12. 2006
10CYP2C9
Clinical relevance of genetic polymorphisms in the human CYP2C9 gene.
Schwarz UI.
Eur J Clin Invest 33 Suppl 2:23-30. Review. 2003
11CYP2B6, CYP2C9, CYP3A4
Expression of CYP3A4, CYP2B6, and CYP2C9 is regulated by the vitamin D receptor pathway in primary human hepatocytes.
Drocourt L, Ourlin JC, Pascussi JM, Maurel P, Vilarem MJ.
J Biol Chem 277(28):25125-32. 2002
12CYP2C18, CYP2C19, CYP2C8, CYP2C9
The human CYP2C locus: a prototype for intergenic and exon repetition splicing events.
Finta C, Zaphiropoulos PG.
Genomics 63(3):433-438. 2000
13CYP2C9
Cytochrome P4502C9: an enzyme of major importance in human drug metabolism.
Miners JO, Birkett DJ.
Br J Clin Pharmacol 45(6):525-38. Review. 1998
14CYP24A1, CYP26A1, CYP27A1, CYP27B1, CYP2A, CYP2@, CYP2A13, CYP2A6, CYP2A7, CYP2A7P1, CYP2B, CYP2B6, CYP2B7P1, CYP2C@, CYP2C18, CYP2C19, CYP2C8, CYP2C9, CYP2D@, CYP2D6, CYP2D7P1, CYP2D7P2, CYP2D8P1, CYP2D8P2, CYP2E1, CYP2F1, CYP2F1P, CYP2G1P, CYP2G2P, CYP2J2, CYP2S1, CYP2T2P, CYP2T3P
Molecular genetics of the human cytochrome P450 monooxygenase superfamily.
Smith G, Stubbins MJ, Harries LW, Wolf CR.
Xenobiotica 28(12):1129-65. Review. No abstract available. 1998
15CYP2C18, CYP2C19, CYP2C8, CYP2C9
A 2.4-megabase physical map spanning the CYP2C gene cluster on chromosome 10q24.
Gray IC, Nobile C, Muresu R, Ford S, Spurr NK.
Genomics 28(2):328-32. 1995
16CYP2C18, CYP2C19, CYP2C8, CYP2C9
Fluorescence in situ hybridization analysis of chromosomal localization of three human cytochrome P450 2C genes (CYP2C8, 2C9, and 2C10) at 10q24.1.
Inoue K, et al.
Jpn J Hum Genet 39 : 337-343. 1994
17CYP2C18, CYP2C9
Gene structure and upstream regulatory regions of human CYP2C9 and CYP2C18.
de Morais SM, Schweikl H, Blaisdell J, Goldstein JA.
Biochem Biophys Res Commun 194(1):194-201. 1993
18CYP2C9
Six-base deletion occurring in messages of human cytochrome P-450 in the CYP2C subfamily results in reduction of tolbutamide hydroxylase activity.
Ohgiya S, Komori M, Ohi H, Shiramatsu K, Shinriki N, Kamataki T.
Biochem Int 27(6):1073-81. 1992
19CYP2C9, CYP2C19
Cloning and expression of complementary DNAs for multiple members of the human cytochromosome P450IIC subfamily.
Romkes M, et al.
Biochemistry 30 : 3247-3255. 1991
20CYP2C9
Human cytochrome P-450 PB-I : a multigene family involved in mephenytoin and steroid oxidations that maps to chromosome 10.
Meehan RR, Gosden JR, Rout D, Hastie ND, Friedberg T, Adesnik M, Buckland R, van Heyningen V, Fletcher J, Spurr NK, et al.
Am J Hum Genet 42 : 26-37. 1988