| 1 | CHRNA6, CHRNB3, CYP2A6
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| Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior.
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| Thorgeirsson TE, Gudbjartsson DF, Surakka I, Vink JM, Amin N, Geller F, Sulem P, Rafnar T, Esko T, Walter S, Gieger C, Rawal R, Mangino M, Prokopenko I, Mägi R, Keskitalo K, Gudjonsdottir IH, Gretarsdottir S, Stefansson H, Thompson JR, Aulchenko YS, Nelis M, Aben KK, den Heijer M, Dirksen A, Ashraf H, Soranzo N, Valdes AM, Steves C, Uitterlinden AG, Hofman A, Tönjes A, Kovacs P, Hottenga JJ, Willemsen G, Vogelzangs N, Döring A, Dahmen N, Nitz B, Pergadia ML, Saez B, De Diego V, Lezcano V, Garcia-Prats MD, Ripatti S, Perola M, Kettunen J, Hartikainen AL, Pouta A, Laitinen J, Isohanni M, Huei-Yi S, Allen M, Krestyaninova M, Hall AS, Jones GT, van Rij AM, Mueller T, Dieplinger B, Haltmayer M, Jonsson S, Matthiasson SE, Oskarsson H, Tyrfingsson T, Kiemeney LA, Mayordomo JI, Lindholt JS, Pedersen JH, Franklin WA, Wolf H, Montgomery GW, Heath AC, Martin NG, Madden PA, Giegling I, Rujescu D, Järvelin MR, Salomaa V, Stumvoll M, Spector TD, Wichmann HE, Metspalu A, Samani NJ, Penninx BW, Oostra BA, Boomsma DI, Tiemeier H, van Duijn CM, Kaprio J, Gulcher JR; ENGAGE Consortium, McCarthy MI, Peltonen L, Thorsteinsdottir U, Stefansson K.
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| Nat Genet 42(5):448-53. Epub 2010 Apr 25.
2010
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| 2 | CYP2A6
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| The mRNA expression of cytochrome P450 isoforms in human gastric tissue.
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| Canturk P, Caner V, Oruc N, Akarca US, Tepeli E, Cetin OG, Zencir S, Topcu Z.
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| Hepatogastroenterology 57(98):372-6.PMID: 20583446 2010
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| 3 | CYP2A6
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| Hepatic CYP2A6 levels and nicotine metabolism: impact of genetic, physiological, environmental, and epigenetic factors.
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| Al Koudsi N, Hoffmann EB, Assadzadeh A, Tyndale RF.
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| Eur J Clin Pharmacol 66(3):239-51. Epub 2009 Dec 9.PMID: 20012030 2010
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| 4 | CYP2A6
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| Structure, function, regulation and polymorphism of human cytochrome P450 2A6.
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| Di YM, Chow VD, Yang LP, Zhou SF.
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| Curr Drug Metab 10(7):754-80.PMID: 19702528 2009
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| 5 | CYP2A6
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| Gene-gene interactions of CYP2A6 and MAOA polymorphisms on smoking behavior in Chinese male population.
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| Tang X, Guo S, Sun H, Song X, Jiang Z, Sheng L, Zhou D, Hu Y, Chen D.
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| Pharmacogenet Genomics 19(5):345-52.PMID: 19415821 2009
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| 6 | CYP2A6
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| CYP2A6 polymorphisms and risk for tobacco-related cancers.
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| Rossini A, de Almeida Simão T, Albano RM, Pinto LF.
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| Pharmacogenomics 9(11):1737-52. Review.PMID: 19018727 2008
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| 7 | CYP2A6
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| Novel and established CYP2A6 alleles impair in vivo nicotine metabolism in a population of Black African descent.
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| Mwenifumbo JC, Al Koudsi N, Ho MK, Zhou Q, Hoffmann EB, Sellers EM, Tyndale RF.
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| Hum Mutat 29(5):679-88.PMID: 18360915 2008
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| 8 | CYP2A6, CYP2B6
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| Gene-gene interactions between CYP2B6 and CYP2A6 in nicotine metabolism.
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| Ring HZ, Valdes AM, Nishita DM, Prasad S, Jacob P 3rd, Tyndale RF, Swan GE, Benowitz NL.
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| Pharmacogenet Genomics 17(12):1007-15.PMID: 18004205 2007
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| 9 | CYP2A6
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| Genetic polymorphism of CYP2A6 as one of the potential determinants of tobacco-related cancer risk.
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| Kamataki T, Fujieda M, Kiyotani K, Iwano S, Kunitoh H.
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| Biochem Biophys Res Commun 338(1):306-10. Epub 2005 Sep 15. Review. 2005
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| 10 | CYP2A6
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| Novel human CYP2A6 alleles confound gene deletion analysis.
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| Nakajima M, Yoshida R, Fukami T, McLeod HL, Yokoi T.
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| FEBS Lett 569(1-3):75-81. 2004
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| 11 | CYP2A6
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| Identification of a single nucleotide polymorphism in the TATA box of the CYP2A6 gene: impairment of its promoter activity.
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| Pitarque M, von Richter O, Oke B, Berkkan H, Oscarson M, Ingelman-Sundberg M.
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| Biochem Biophys Res Commun 284(2):455-60. 2001
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| 12 | CYP2A13, CYP2A6, CYP2A7, CYP2A7P1, CYP2B, CYP2B7P1, CYP2F1, CYP2F1P, CYP2G1P, CYP2T2P
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| Organization, structure and evolution of the CYP2 gene cluster on human chromosome 19.
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| Hoffman SM, Nelson DR, Keeney DS.
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| Pharmacogenetics 11(8):687-98. Review. 2001
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| 13 | CYP2A13, CYP2A6, CYP2A7
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| Human cytochrome P450 CYP2A13: predominant expression in the respiratory tract and its high efficiency metabolic activation of a tobacco-specific carcinogen, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.
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| Su T, Bao Z, Zhang QY, Smith TJ, Hong JY, Ding X.
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| Cancer Res 60(18):5074-9. 2000
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| 14 | CYP2A6
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| CYP2A6: a human coumarin 7-hydroxylase.
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| Pelkonen O, Rautio A, Raunio H, Pasanen M.
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| Toxicology 144(1-3):139-47. Review. 2000
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| 15 | CYP2A6
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| Homologous unequal cross-over within the human CYP2A gene cluster as a mechanism for the deletion of the entire CYP2A6 gene associated with the poor metabolizer phenotype.
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| Nunoya Ki, Yokoi T, Takahashi Y, Kimura K, Kinoshita M, Kamataki T.
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| J Biochem (Tokyo) 126(2):402-7 1999
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| 16 | CYP2A6
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| CYP2A6 gene deletion reduces susceptibility to lung cancer.
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| Miyamoto M, Umetsu Y, Dosaka-Akita H, Sawamura Y, Yokota J, Kunitoh H, Nemoto N, Sato K, Ariyoshi N, Kamataki T.
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| Biochem Biophys Res Commun 261(3):658-60 1999
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| 17 | CYP2A6
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| Identification and characterisation of novel polymorphisms in the CYP2A locus: implications for nicotine metabolism.
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| Oscarson M, McLellan RA, Gullsten H, Agundez JA, Benitez J, Rautio A, Raunio H, Pelkonen O, Ingelman-Sundberg M.
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| FEBS Lett 460(2):321-7 1999
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| 18 | CYP2A6
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| Genotyping of human cytochrome P450 2A6 (CYP2A6), a nicotine C-oxidase.
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| Oscarson M, Gullsten H, Rautio A, Bernal ML, Sinues B, Dahl ML, Stengard JH, Pelkonen O, Raunio H, Ingelman-Sundberg M.
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| FEBS Lett 438 : 201-205. 1998
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| 19 | CYP24A1, CYP26A1, CYP27A1, CYP27B1, CYP2A, CYP2@, CYP2A13, CYP2A6, CYP2A7, CYP2A7P1, CYP2B, CYP2B6, CYP2B7P1, CYP2C@, CYP2C18, CYP2C19, CYP2C8, CYP2C9, CYP2D@, CYP2D6, CYP2D7P1, CYP2D7P2, CYP2D8P1, CYP2D8P2, CYP2E1, CYP2F1, CYP2F1P, CYP2G1P, CYP2G2P, CYP2J2, CYP2S1, CYP2T2P, CYP2T3P
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| Molecular genetics of the human cytochrome P450 monooxygenase superfamily.
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| Smith G, Stubbins MJ, Harries LW, Wolf CR.
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| Xenobiotica 28(12):1129-65. Review. No abstract available. 1998
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| 20 | CYP2A6
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| A genetic polymorphism in coumarin 7-hydroxylation : sequence of the human CYP2A genes and identification of variant CYP2A6 alleles.
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| Fernandez-Salguero P, et al.
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| Am J Hum Genet 57 : 651-660. 1995
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| 21 | CYP2A6, CYP2B7P1, CYP2T2P, CYP2T3P, CYP2T3P
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| The CYP2A gene subfamily: species differences, regulation, catalytic activities and role in chemical carcinogenesis.
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| Fernandez-Salguero P, Gonzalez FJ.
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| Pharmacogenetics 5 Spec No:S123-8. Review. 1995
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| 22 | CYP2A6, CYP2B7P1, CYP2F1P, CYP2T2P, CYP2T3P
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| A genetic polymorphism in coumarin 7-hydroxylation: sequence of the human CYP2A genes and identification of variant CYP2A6 alleles.
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| Fernandez-Salguero P, Hoffman SM, Cholerton S, Mohrenweiser H, Raunio H, Rautio A, Pelkonen O, Huang JD, Evans WE, Idle JR, et al.
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| Am J Hum Genet 57(3):651-60. 1995
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| 23 | CYP2A13, CYP2A6, CYP2A7, CYP2A7P1
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| An XmnI RFLP for CYP2A on chromosome 19.
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| McCure JA, et al.
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| Nucleic Acids Res 19 : 5089. 1991
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| 24 | CYP2A6
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| The CYP2A3 gene product catalyzes coumarin 7-hydroxylation in human liver microsomes.
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| Yamano S, Tatsuno J, Gonzalez FJ.
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| Biochemistry 29(5):1322-9. 1990
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| 25 | CYP2A6
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| cDNA and deduced amino acid sequences of human P450 IIA3 (CYP2A3).
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| Yamano S, Nagata K, Yamazoe Y, Kato R, Gelboin HV, Gonzalez FJ.
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| Nucleic Acids Res 17(12):4888. No abstract available. 1989
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