Citations for
1CXCL1, CXCL2
CXCL1 and CXCL2 Inhibit the Axon Outgrowth in a Time- and Cell-Type-Dependent Manner in Adult Rat Dorsal Root Ganglia Neurons.
Deftu AT, Ciorescu R, Gheorghe RO, Mihăilescu D, Ristoiu V.
Neurochem Res 44(9):2215-2229. doi: 10.1007/s11064-019-02861-x. Epub 2019 Aug 17. 2019
2CXCL1
CXCL1 stimulates migration and invasion in ER‑negative breast cancer cells via activation of the ERK/MMP2/9 signaling axis.
Yang C, Yu H, Chen R, Tao K, Jian L, Peng M, Li X, Liu M, Liu S.
Int J Oncol 55(3):684-696. doi: 10.3892/ijo.2019.4840. Epub 2019 Jul 15. 2019
3CXCL1
CXC chemokine ligand 1 mediates adiponectin-induced angiogenesis in ovarian cancer.
Ouh YT, Cho HW, Lee JK, Choi SH, Choi HJ, Hong JH.
Tumour Biol 42(4):1010428319842699. doi: 10.1177/1010428319842699. 2019
4BSG, CXCL1
CD147 Promotes CXCL1 Expression and Modulates Liver Fibrogenesis.
Shi WP, Ju D, Li H, Yuan L, Cui J, Luo D, Chen ZN, Bian H.
Int J Mol Sci 19(4). pii: E1145. doi: 10.3390/ijms19041145. 2018
5CXCL1
Bronchial epithelial cells produce CXCL1 in response to LPS and TNFα: A potential role in the pathogenesis of COPD.
Inui T, Watanabe M, Nakamoto K, Sada M, Hirata A, Nakamura M, Honda K, Ogawa Y, Takata S, Yokoyama T, Saraya T, Kurai D, Wada H, Ishii H, Takizawa H.
Exp Lung Res 44(7):323-331. doi: 10.1080/01902148.2018.1520936. Epub 2019 Jan 24. 2018
6ACKR1, CXCL1, CXCL2
Distinct Compartmentalization of the Chemokines CXCL1 and CXCL2 and the Atypical Receptor ACKR1 Determine Discrete Stages of Neutrophil Diapedesis.
Girbl T, Lenn T, Perez L, Rolas L, Barkaway A, Thiriot A, Del Fresno C, Lynam E, Hub E, Thelen M, Graham G, Alon R, Sancho D, von Andrian UH, Voisin MB, Rot A, Nourshargh S.
Immunity 49(6):1062-1076.e6. doi: 10.1016/j.immuni.2018.09.018. Epub 2018 Nov 13. 2018
7CXCL1, CXCL2
Chemokine (C-X-C motif) ligand 1 and CXCL2 produced by tumor promote the generation of monocytic myeloid-derived suppressor cells.
Shi H, Han X, Sun Y, Shang C, Wei M, Ba X, Zeng X.
Cancer Sci 109(12):3826-3839. doi: 10.1111/cas.13809. Epub 2018 Nov 8. 2018
8CXCL1
Inflammation-induced Gro1 triggers senescence in neuronal progenitors: effects of estradiol.
Zonis S, Breunig JJ, Mamelak A, Wawrowsky K, Bresee C, Ginzburg N, Chesnokova V.
J Neuroinflammation 15(1):260. doi: 10.1186/s12974-018-1298-y. 2018
9CXCL1
CXCL1 derived from tumor-associated macrophages promotes breast cancer metastasis via activating NF-κB/SOX4 signaling.
Wang N, Liu W, Zheng Y, Wang S, Yang B, Li M, Song J, Zhang F, Zhang X, Wang Q, Wang Z.
Cell Death Dis 9(9):880. doi: 10.1038/s41419-018-0876-3. 2018
10CXCL1
Chemokine (C-X-C motif) ligand 1 is associated with tumor progression and poor prognosis in patients with colorectal cancer.
Zhuo C, Wu X, Li J, Hu D, Jian J, Chen C, Zheng X, Yang C.
Biosci Rep 38(4). pii: BSR20180580. doi: 10.1042/BSR20180580. Print 2018 Aug 31. 2018
11CXCL1, CXCL2, CXCR2, NLRP3
CXCL1 and CXCL2 Regulate NLRP3 Inflammasome Activation via G-Protein-Coupled Receptor CXCR2.
Boro M, Balaji KN.
J Immunol 199(5):1660-1671. doi: 10.4049/jimmunol.1700129. Epub 2017 Jul 24. 2017
12CXCL1
CXCL1 from tumor-associated lymphatic endothelial cells drives gastric cancer cell into lymphatic system via activating integrin β1/FAK/AKT signaling.
Wang Z, Wang Z, Li G, Wu H, Sun K, Chen J, Feng Y, Chen C, Cai S, Xu J, He Y.
Cancer Lett 385:28-38. doi: 10.1016/j.canlet.2016.10.043. Epub 2016 Nov 8. 2017
13CXCL1, IL8, STAT3
Endoplasmic Reticulum Stress and Chemokine Production in Cystic Fibrosis Airway Cells: Regulation by STAT3 Modulation.
Tang AC, Saferali A, He G, Sandford AJ, Strug LJ, Turvey SE.
J Infect Dis 215(2):293-302. doi: 10.1093/infdis/jiw516. 2017
14CXCL1
Tumor-Derived CXCL1 Promotes Lung Cancer Growth via Recruitment of Tumor-Associated Neutrophils.
Yuan M, Zhu H, Xu J, Zheng Y, Cao X, Liu Q.
J Immunol Res 2016:6530410. doi: 10.1155/2016/6530410. Epub 2016 Jun 29. 2016
15CXCL1
CXCL1 mediates obesity-associated adipose stromal cell trafficking and function in the tumour microenvironment.
Zhang T, Tseng C, Zhang Y, Sirin O, Corn PG, Li-Ning-Tapia EM, Troncoso P, Davis J, Pettaway C, Ward J, Frazier ML, Logothetis C, Kolonin MG.
Nat Commun 7:11674. doi: 10.1038/ncomms11674. 2016
16CXCL1
CXCL1/MGSA Is a Novel Glycosaminoglycan (GAG)-binding Chemokine: STRUCTURAL EVIDENCE FOR TWO DISTINCT NON-OVERLAPPING BINDING DOMAINS.
Sepuru KM, Rajarathnam K.
J Biol Chem 291(8):4247-55. doi: 10.1074/jbc.M115.697888. Epub 2015 Dec 31. 2016
17CXCL1
Urine CXCL1 as a biomarker for tumor detection and outcome prediction in bladder cancer.
Nakashima M, Matsui Y, Kobayashi T, Saito R, Hatahira S, Kawakami K, Nakamura E, Nishiyama H, Ogawa O.
Cancer Biomark 15(4):357-64. doi: 10.3233/CBM-150472. 2015
18CXCL1, CXCR2
Chemokine CXCL1-Mediated Neutrophil Trafficking in the Lung: Role of CXCR2 Activation.
Sawant KV, Xu R, Cox R, Hawkins H, Sbrana E, Kolli D, Garofalo RP, Rajarathnam K.
J Innate Immun 7(6):647-58. doi: 10.1159/000430914. Epub 2015 Jul 1. 2015
19CXCL1
Urinary CXCL1: a novel predictor of IgA nephropathy progression.
Zhao Y, Zhu L, Zhou T, Zhang Q, Shi S, Liu L, Lv J, Zhang H.
PLoS One 10(3):e0119033. doi: 10.1371/journal.pone.0119033. eCollection 2015. 2015
20CXCL1, CXCL2
NF-κB and STAT1 control CXCL1 and CXCL2 gene transcription.
Burke SJ, Lu D, Sparer TE, Masi T, Goff MR, Karlstad MD, Collier JJ.
Am J Physiol Endocrinol Metab 306(2):E131-49. doi: 10.1152/ajpendo.00347.2013. Epub 2013 Nov 26. 2014
21CXCL1
CXCL1 regulation in human pulmonary epithelial cells by tumor necrosis factor.
Shieh JM, Tsai YJ, Tsou CJ, Wu WB.
Cell Physiol Biochem 34(4):1373-84. doi: 10.1159/000366344. Epub 2014 Oct 2. 2014
22CXCL1
CXCL1 contributes to host defense in polymicrobial sepsis via modulating T cell and neutrophil functions.
Jin L, Batra S, Douda DN, Palaniyar N, Jeyaseelan S.
J Immunol 193(7):3549-58. doi: 10.4049/jimmunol.1401138. Epub 2014 Aug 29. 2014
23CXCL1
Neutrophils recruited by chemoattractants in vivo induce microvascular plasma protein leakage through secretion of TNF.
Finsterbusch M, Voisin MB, Beyrau M, Williams TJ, Nourshargh S.
J Exp Med 211(7):1307-14. doi: 10.1084/jem.20132413. Epub 2014 Jun 9. 2014
24CXCL1, CXCL2
Mast cell and macrophage chemokines CXCL1/CXCL2 control the early stage of neutrophil recruitment during tissue inflammation.
De Filippo K, Dudeck A, Hasenberg M, Nye E, van Rooijen N, Hartmann K, Gunzer M, Roers A, Hogg N.
Blood 121(24):4930-7. doi: 10.1182/blood-2013-02-486217. Epub 2013 May 3. 2013
25CXCL1, CXCL10, ICAM1, IL1A
IL-1 alpha regulates CXCL1, CXCL10 and ICAM1 in network form in oral keratinocytes.
Wu T, Du R, Hong Y, Jia L, Zeng Q, Cheng B.
Clin Lab 59(9-10):1105-11. 2013
26CXCL1, IL6ST
Elevated CXCL1 expression in gp130-deficient endothelial cells impairs neutrophil migration in mice.
Yao L, Yago T, Shao B, Liu Z, Silasi-Mansat R, Setiadi H, Lupu F, McEver RP.
Blood 122(23):3832-42. doi: 10.1182/blood-2012-12-473835. Epub 2013 Sep 30. 2013
27CXCL1, CXCL2, LSP1
Different microvascular permeability responses elicited by the CXC chemokines MIP-2 and KC during leukocyte recruitment: role of LSP1.
Lei X, Hossain M, Qadri SM, Liu L.
Biochem Biophys Res Commun 423(3):484-9. doi: 10.1016/j.bbrc.2012.05.146. Epub 2012 Jun 5. 2012
28CXCL1, IL17A
IL-17 regulates CXCL1 mRNA stability via an AUUUA/tristetraprolin-independent sequence.
Datta S, Novotny M, Pavicic PG Jr, Zhao C, Herjan T, Hartupee J, Hamilton T.
J Immunol 184(3):1484-91. Epub 2009 Dec 30.PMID: 20042592 2010
29CXCL1
Identification of GRO1 as a critical determinant for mutant p53 gain of function.
Yan W, Chen X.
J Biol Chem 284(18):12178-87. Epub 2009 Mar 3.PMID: 19258312 2009
30CXCL1
Neuroprotection and remyelination after autoimmune demyelination in mice that inducibly overexpress CXCL1.
Omari KM, Lutz SE, Santambrogio L, Lira SA, Raine CS.
Am J Pathol 174(1):164-76. Epub 2008 Dec 18.PMID: 19095949 2009
31CCL4, CXCL1, IL8, PROK1
Prokineticin 1 induces CCL4, CXCL1 and CXCL8 in human monocytes but not in macrophages and dendritic cells.
Monnier J, Quillien V, Piquet-Pellorce C, Leberre C, Preisser L, Gascan H, Samson M.
Eur Cytokine Netw 19(4):166-75.PMID: 19103522 2008
32CXCL1, CXCL2
Involvement of KC, MIP-2, and MCP-1 in leukocyte infiltration following injection of necrotic cells into the peritoneal cavity.
Tanimoto N, Terasawa M, Nakamura M, Kegai D, Aoshima N, Kobayashi Y, Nagata K.
Biochem Biophys Res Commun 361(2):533-6. Epub 2007 Jul 23. 2007
33CXCL1
The chemokine growth-regulated oncogene 1 (Gro-1) links RAS signaling to the senescence of stromal fibroblasts and ovarian tumorigenesis.
Yang G, Rosen DG, Zhang Z, Bast RC Jr, Mills GB, Colacino JA, Mercado-Uribe I, Liu J.
Proc Natl Acad Sci U S A 103(44):16472-7. Epub 2006 Oct 23. 2006
34IL8, CXCL1
IL-8/CXCL8 and growth-related oncogene alpha/CXCL1 induce chondrocyte hypertrophic differentiation.
Merz D, Liu R, Johnson K, Terkeltaub R.
J Immunol 171(8):4406-15. 2003
35CD74, DEFA5, DEFA6, ESD, CXCL1, IGHG3, IGLL2, LCN2, REG3A, PI3, REG1A, S100A9, S100P
Ulcerative colitis and Crohn's disease : distinctive gene expression profiles and novel susceptibility candidate genes.
Lawrance IC, Fiocchi C, Chakravarti S.
Hum Mol Genet 10(5):445-56. 2001
36CXCL1, CXCL2
Identification of known and novel genes in activated monocytes from patients with rheumatoid arthritis.
Stuhlmuller B, Ungethum U, Scholze S, Martinez L, Backhaus M, Kraetsch HG, Kinne RW, Burmester GR.
Arthritis Rheum 43(4):775-90. 2000
37CXCL1
Neutrophil gelatinase B potentiates interleukin-8 tenfold by aminoterminal processing, whereas it degrades CTAP-III, PF-4, and GRO-alpha and leaves RANTES and MCP-2 intact.
Van den Steen PE, Proost P, Wuyts A, Van Damme J, Opdenakker G.
Blood 96(8):2673-81.PMID: 11023497 2000
38CXCL1, CXCL2, CXCL3
Identification of three related human GRO genes encoding cytokine functions.
Haskill S, et al.
Proc Natl Acad Sci U S A 87 : 7732-7736. 1990
39CXCL1
Mouse melanoma growth stimulatory activity gene is polymorphic and syntenic with Kit, Rumpwhite, Patch and recessive spotting loci on chromosome 5.
Sakaguchi AY, et al.
(HGM10) Cytogenet Cell Genet 51 : 1072. 1989
40CXCL1
A ScaI RFLP demonstrated for the GRO gene on chromosome 4.
Beck JS, et al.
Nucleic Acids Res 17 : 8895. 1989
41CXCL1
Functional diversity of gro gene expression in human fibroblats and mammary epithelial cells.
Anisowicz A, et al.
Proc Natl Acad Sci U S A 85 : 9645-9649. 1988
42CXCL1
Molecular characterization and chromosomal mapping of melanoma growth stimulatory activity, a growth factor structurally related to beta-thrombo-globulin.
Richmond A, et al.
EMBO J 7 : 2025-2033. 1988
43CXCL1
Constitutive over-expression of a growth-regulated gene in transformed Chinese hamster and human cells.
Anisowicz A, et al.
Proc Natl Acad Sci U S A 84 : 7188-7192. 1987