Citations for
1CX3CL1, CX3CR1
CX3CR1 is required for airway inflammation by promoting T helper cell survival and maintenance in inflamed lung.
Mionnet C, Buatois V, Kanda A, Milcent V, Fleury S, Lair D, Langelot M, Lacoeuille Y, Hessel E, Coffman R, Magnan A, Dombrowicz D, Glaichenhaus N, Julia V.
Nat Med 16(11):1305-12. Epub 2010 Oct 31. 2010
2CX3CL1
Down-regulation of fractalkine inhibits the in vitro and in vivo angiogenesis of the hepatocellular carcinoma HepG2 cells.
Li F, Wang Z, Liu Y, Li J.
Oncol Rep 24(3):669-75. 2010
3CX3CL1
Requirements for leukocyte transmigration via the transmembrane chemokine CX3CL1.
Schwarz N, Pruessmeyer J, Hess FM, Dreymueller D, Pantaler E, Koelsch A, Windoffer R, Voss M, Sarabi A, Weber C, Sechi AS, Uhlig S, Ludwig A.
Cell Mol Life Sci 67(24):4233-48. Epub 2010 Jun 18. 2010
4CX3CL1
Distinct role of the intracellular C-terminus for subcellular expression, shedding and function of the murine transmembrane chemokine CX3CL1.
Andrzejewski MG, Koelsch A, Kogel T, Dreymueller D, Schwarz N, Ludwig A.
Biochem Biophys Res Commun 395(2):178-84. Epub 2010 Mar 27. 2010
5CX3CL1, CX3CR1
Role of CX3CL1/fractalkine in osteoclast differentiation and bone resorption.
Koizumi K, Saitoh Y, Minami T, Takeno N, Tsuneyama K, Miyahara T, Nakayama T, Sakurai H, Takano Y, Nishimura M, Imai T, Yoshie O, Saiki I.
J Immunol 183(12):7825-31. Epub . 2009
6CX3CL1
Constitutive endocytosis of the chemokine CX3CL1 prevents its degradation by cell surface metalloproteases.
Huang YW, Su P, Liu GY, Crow MR, Chaukos D, Yan H, Robinson LA.
J Biol Chem 284(43):29644-53. Epub 2009 Sep 1. 2009
7CX3CL1
CX3CL1/fractalkine shedding by human hepatic stellate cells: contribution to chronic inflammation in the liver.
Bourd-Boittin K, Basset L, Bonnier D, L'helgoualc'h A, Samson M, Théret N.
J Cell Mol Med 13(8A):1526-35. Epub 2009 May 11. 2009
8CX3CL1, RETN
Resistin up-regulates fractalkine expression in human endothelial cells: lack of additive effect with TNF-alpha.
Manduteanu I, Dragomir E, Calin M, Pirvulescu M, Gan AM, Stan D, Simionescu M.
Biochem Biophys Res Commun 381(1):96-101. Epub 2009 Feb 11. 2009
9CX3CL1, CX3CR1
Functional adhesiveness of the CX3CL1 chemokine requires its aggregation. Role of the transmembrane domain.
Hermand P, Pincet F, Carvalho S, Ansanay H, Trinquet E, Daoudi M, Combadière C, Deterre P.
J Biol Chem 283(44):30225-34. Epub 2008 Aug 25. 2008
10CCL14, CX3CL1
CX3CL1 and CCL14 regulate extracellular matrix and adhesion molecules in the trophoblast: potential roles in human embryo implantation.
Hannan NJ, Salamonsen LA.
Biol Reprod 79(1):58-65. Epub 2008 Mar 26. 2008
11CX3CL1
Cytokine expression profiling of the myocardium reveals a role for CX3CL1 (fractalkine) in heart failure.
Husberg C, Nygård S, Finsen AV, Damås JK, Frigessi A, Oie E, Waehre A, Gullestad L, Aukrust P, Yndestad A, Christensen G.
J Mol Cell Cardiol 45(2):261-9. Epub 2008 May 28. 2008
12CX3CR1, CX3CL1
The CX3CL1-CX3CR1 system and psoriasis.
Plant D, Young HS, Watson RE, Worthington J, Griffiths CE.
Exp Dermatol 15(11):900-3. 2006
13CCL14, CCL4, CX3CL1
The chemokines, CX3CL1, CCL14, and CCL4, promote human trophoblast migration at the feto-maternal interface.
Hannan NJ, Jones RL, White CA, Salamonsen LA.
Biol Reprod 74(5):896-904. Epub 2006 Feb 1. 2006
14CX3CL1
Fractalkine (CX3CL1) stimulated by nuclear factor kappaB (NF-kappaB)-dependent inflammatory signals induces aortic smooth muscle cell proliferation through an autocrine pathway.
Chandrasekar B, Mummidi S, Perla RP, Bysani S, Dulin NO, Liu F, Melby PC.
Biochem J 373(Pt 2):547-58. 2003
15CX3CL1, ADAM10
The disintegrin-like metalloproteinase ADAM10 is involved in constitutive cleavage of CX3CL1 (fractalkine) and regulates CX3CL1-mediated cell-cell adhesion.
Hundhausen C, Misztela D, Berkhout TA, Broadway N, Saftig P, Reiss K, Hartmann D, Fahrenholz F, Postina R, Matthews V, Kallen KJ, Rose-John S, Ludwig A.
Blood 102(4):1186-95. Epub 2003 Apr 24. 2003
16CX3CL1
Fractalkine is expressed by smooth muscle cells in response to IFN-gamma and TNF-alpha and is modulated by metalloproteinase activity.
Ludwig A, Berkhout T, Moores K, Groot P, Chapman G.
J Immunol 168(2):604-12. 2002
17CCL17, CCL22, CX3CL1
Linked chromosome 16q13 chemokines, macrophage-derived chemokine, fractalkine, and thymus- and activation-regulated chemokine, are expressed in human atherosclerotic lesions.
Greaves DR, Hakkinen T, Lucas AD, Liddiard K, Jones E, Quinn CM, Senaratne J, Green FR, Tyson K, Boyle J, Shanahan C, Weissberg PL, Gordon S, Yla-Hertualla S.
Arterioscler Thromb Vasc Biol 21(6):923-9. 2001
18CX3CL1, CX3CR1
Molecular determinants of receptor binding and signaling by the CX3C chemokine fractalkine.
Mizoue LS, Sullivan SK, King DS, Kledal TN, Schwartz TW, Bacon KB, Handel TM.
J Biol Chem 276(36):33906-14. 2001
19ADAM17, CX3CL1
Tumor necrosis factor-alpha-converting enzyme (ADAM17) mediates the cleavage and shedding of fractalkine (CX3CL1).
Garton KJ, Gough PJ, Blobel CP, Murphy G, Greaves DR, Dempsey PJ, Raines EW.
J Biol Chem 276(41):37993-8001. 2001
20CX3CR1, CX3CL1
Solution structure and dynamics of the CX3C chemokine domain of fractalkine and its interaction with an N-terminal fragment of CX3CR1.
Mizoue LS, et al.
Biochemistry 38(5):1402-14. 1999
21CX3CL1
Fractalkine and macrophage-derived chemokine: T cell-attracting chemokines expressed in T cell area dendritic cells.
Kanazawa N, et al.
Eur J Immunol 29(6):1925-32. 1999
22CX3CL1
Fractalkine, a CX3C chemokine, is expressed by dendritic cells and is up-regulated upon dendritic cell maturation.
Papadopoulos EJ, Sassetti C, Saeki H, Yamada N, Kawamura T, Fitzhugh DJ, Saraf MA, Schall T, Blauvelt A, Rosen SD, Hwang ST.
Eur J Immunol 29(8):2551-9 1999
23ABCC11, ABCC6P1, ABCC6P2, ACYP2, APOB48R, CCL22, CCP110, CDC37, CIAPIN1, CLN3, COQ9, CX3CL1, CXCR3, DDX28, DHX38, DOK4, EARS2, EARS2, EIF3CL, GDE1, GTF3C1, LKAP, MAZ, NOMO1, NOMO2, NPIP, NUPR1, ORIPL, PMFBP1, RBKH, SLC7A5P1, TCCK, UBFD1, XPO6, ZG16, ZP2
Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q.
Loftus BJ, Kim UJ, Sneddon VP, Kalush F, Brandon R, Fuhrmann J, Mason T,Crosby ML, Barnstead M, Cronin L, Deslattes Mays A, Cao Y, Xu RX, Kang HL,Mitchell S, Eichler EE, Harris PC, Venter JC, Adams MD.
Genomics 60(3):295-308. 1999
24CCL17, CCL22, CX3CL1
Human chemokines fractalkine (SCYD1), MDC (SCYA22) and TARC (SCYA17) are clustered on chromosome 16q13.
Nomiyama H, et al.
Cytogenet Cell Genet 81 : 10-11. 1998
25CX3CL1
Neurotactin, a membrane-anchored chemokine upregulated in brain inflammation.
Pan Y, Lloyd C, Zhou H, Dolich S, Deeds J, Gonzalo JA, Vath J, Gosselin M, Ma J, Dussault B, Woolf E, Alperin G, Culpepper J, Gutierrez-Ramos JC, Gearing D.
Nature 387(6633):611-7. 1997
26CX3CR1, CX3CL1
A new class of membrane-bound chemokine with a CX3C motif.
Bazan JF, Bacon KB, Hardiman G, Wang W, Soo K, Rossi D, Greaves DR, Zlotnik A, Schall TJ.
Nature 385(6617):640-4. 1997