Citations for
1CUL2, CUL4B, CUL5
Association of mRNA expression levels of Cullin family members with prognosis in breast cancer: An online database analysis.
Liu A, Zhang S, Shen Y, Lei R, Wang Y.
Medicine (Baltimore) Aug;98(31):e16625. doi: 10.1097/MD.0000000000016625 2019
2CUL2
Novel Class of Viral Ankyrin Proteins Targeting the Host E3 Ubiquitin Ligase Cullin-2.
Odon V, Georgana I, Holley J, Morata J, Maluquer de Motes C.
J Virol. Nov 12;92(23):e01374-18. doi: 10.1128/JVI.01374-18. Print 2018 Dec 1 2018
3CUL2, ELOB, ELOC, PTCH1, ZYG11B
The C-terminal cytoplasmic tail of hedgehog receptor Patched1 is a platform for E3 ubiquitin ligase complexes.
Yamaki Y, Kagawa H, Hatta T, Natsume T, Kawahara H.
Mol Cell Biochem. Mar;414(1-2):1-12. doi: 10.1007/s11010-015-2643-4. Epub 2016 Feb 17 2016
4CUL2, DCUN1D1, SQSTM1
Regulation of glucose metabolism by p62/SQSTM1 through HIF1α.
Chen K, Zeng J, Xiao H, Huang C, Hu J, Yao W, Yu G, Xiao W, Xu H, Ye Z.
J Cell Sci. Feb 15;129(4):817-30. doi: 10.1242/jcs.178756. Epub 2016 Jan 7 2016
5CUL2, ELOB, ELOC, VHL
Insights into Cullin-RING E3 ubiquitin ligase recruitment: structure of the VHL-EloBC-Cul2 complex.
Nguyen HC, Yang H, Fribourgh JL, Wolfe LS, Xiong Y.
Structure Mar 3;23(3):441-449. doi: 10.1016/j.str.2014.12.014. Epub 2015 Feb 5 2015
6CUL2, DCUN1D1
DCNL1 functions as a substrate sensor and activator of cullin 2-RING ligase.
Heir P, Sufan RI, Greer SN, Poon BP, Lee JE, Ohh M.
Mol Cell Biol. Apr;33(8):1621-31. doi: 10.1128/MCB.01342-12. Epub 2013 Feb 11 2013
7CUL2, HIF1A, UBXN7
UBXN7 docks on neddylated cullin complexes using its UIM motif and causes HIF1α accumulation.
Bandau S, Knebel A, Gage ZO, Wood NT, Alexandru G.
BMC Biol Apr 26;10:36. doi: 10.1186/1741-7007-10-36 2012
8CUL2, PRAME
The tumour antigen PRAME is a subunit of a Cul2 ubiquitin ligase and associates with active NFY promoters.
Costessi A, Mahrour N, Tijchon E, Stunnenberg R, Stoel MA, Jansen PW, Sela D, Martin-Brown S, Washburn MP, Florens L, Conaway JW, Conaway RC, Stunnenberg HG.
EMBO J 30(18):3786-98. doi: 10.1038/emboj.2011.262. 2011
9CUL2, CUL5
Cullin-5 and cullin-2 play a role in the development of neuromuscular junction and the female germ line of Drosophila.
Ayyub C.
J Genet. Aug;90(2):239-49. doi: 10.1007/s12041-011-0062-1 2011
10CUL2, CUL5
Cullin-5 and cullin-2 play a role in the development of neuromuscular junction and the female germ line of Drosophila.
Ayyub C.
J Genet. Aug;90(2):239-49. doi: 10.1007/s12041-011-0062-1 2011
11CUL2
CUL2 is required for the activity of hypoxia-inducible factor and vasculogenesis.
Maeda Y, Suzuki T, Pan X, Chen G, Pan S, Bartman T, Whitsett JA.
J Biol Chem 283(23):16084-92. Epub 2008 Mar 27. 2008
12CAND1, CUL1, CUL2, CUL3, CUL4A, CUL4B
TIP120A associates with cullins and modulates ubiquitin ligase activity.
Min KW, Hwang JW, Lee JS, Park Y, Tamura TA, Yoon JB.
J Biol Chem 278(18):15905-10. Epub 2003 Feb 27. 2003
13CUL2, ELOC, HIF1A, VHL
Activation of HIF1alpha ubiquitination by a reconstituted von Hippel-Lindau (VHL) tumor suppressor complex.
Kamura T, Sato S, Iwai K, Czyzyk-Krzeska M, Conaway RC, Conaway JW.
Proc Natl Acad Sci U S A 97(19):10430-5. 2000
14CUL2, VBP1
Genomic organization and chromosomal localization of the human CUL2 gene and the role of von hippel-lindau tumor suppressor-binding protein (CUL2 and VBP1) mutation and loss in renal-cell carcinoma development.
Clifford SC, et al.
Genes Chromosomes Cancer 26(1):20-8. 1999
15CUL2, NEDD8, VHL
The von Hippel-Lindau tumor suppressor gene product promotes, but is not essential for, NEDD8 conjugation to cullin-2.
Wada H, Yeh ET, Kamitani T.
J Biol Chem 274(50):36025-9. 1999
16CUL2, CUL4A, NEDD8
Identification of NEDD8-conjugation site in human cullin-2.
Wada H, Yeh ET, Kamitani T.
Biochem Biophys Res Commun 257(1):100-5. 1999
17CUL2, ELOB, ELOC, VHL
Regulation of hypoxia-inducible mRNAs by the von Hippel-Lindau tumor suppressor protein requires binding to complexes containing elongins B/C and Cul2.
Lonergan KM, Iliopoulos O, Ohh M, Kamura T, Conaway RC, Conaway JW, Kaelin WG Jr.
Mol Cell Biol 18(2):732-41. 1998
18CUL2, VHL
The von Hippel-Lindau tumor-suppressor gene product forms a stable complex with human CUL-2, a member of the Cdc53 family of proteins.
Pause A, et al.
Proc Natl Acad Sci U S A 94 : 2156-2161. 1997
19CUL1, CUL2, CUL3, CUL4A, CUL4B, CUL5
cul-1 is required for cell cycle exit in C. elegans and identifies a novel gene family.
Kipreos ET, Lander LE, Wing JP, He WW, Hedgecock EM.
Cell 85(6):829-39. 1996