1 | CUL2, CUL4B, CUL5
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| Association of mRNA expression levels of Cullin family members with prognosis in breast cancer: An online database analysis.
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| Liu A, Zhang S, Shen Y, Lei R, Wang Y.
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| Medicine (Baltimore) Aug;98(31):e16625. doi: 10.1097/MD.0000000000016625 2019
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2 | CUL2
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| Novel Class of Viral Ankyrin Proteins Targeting the Host E3 Ubiquitin Ligase Cullin-2.
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| Odon V, Georgana I, Holley J, Morata J, Maluquer de Motes C.
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| J Virol. Nov 12;92(23):e01374-18. doi: 10.1128/JVI.01374-18. Print 2018 Dec 1 2018
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3 | CUL2, ELOB, ELOC, PTCH1, ZYG11B
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| The C-terminal cytoplasmic tail of hedgehog receptor Patched1 is a platform for E3 ubiquitin ligase complexes.
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| Yamaki Y, Kagawa H, Hatta T, Natsume T, Kawahara H.
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| Mol Cell Biochem. Mar;414(1-2):1-12. doi: 10.1007/s11010-015-2643-4. Epub 2016 Feb 17 2016
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4 | CUL2, DCUN1D1, SQSTM1
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| Regulation of glucose metabolism by p62/SQSTM1 through HIF1α.
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| Chen K, Zeng J, Xiao H, Huang C, Hu J, Yao W, Yu G, Xiao W, Xu H, Ye Z.
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| J Cell Sci. Feb 15;129(4):817-30. doi: 10.1242/jcs.178756. Epub 2016 Jan 7 2016
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5 | CUL2, ELOB, ELOC, VHL
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| Insights into Cullin-RING E3 ubiquitin ligase recruitment: structure of the VHL-EloBC-Cul2 complex.
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| Nguyen HC, Yang H, Fribourgh JL, Wolfe LS, Xiong Y.
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| Structure Mar 3;23(3):441-449. doi: 10.1016/j.str.2014.12.014. Epub 2015 Feb 5 2015
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6 | CUL2, DCUN1D1
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| DCNL1 functions as a substrate sensor and activator of cullin 2-RING ligase.
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| Heir P, Sufan RI, Greer SN, Poon BP, Lee JE, Ohh M.
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| Mol Cell Biol. Apr;33(8):1621-31. doi: 10.1128/MCB.01342-12. Epub 2013 Feb 11 2013
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7 | CUL2, HIF1A, UBXN7
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| UBXN7 docks on neddylated cullin complexes using its UIM motif and causes HIF1α accumulation.
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| Bandau S, Knebel A, Gage ZO, Wood NT, Alexandru G.
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| BMC Biol Apr 26;10:36. doi: 10.1186/1741-7007-10-36 2012
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8 | CUL2, PRAME
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| The tumour antigen PRAME is a subunit of a Cul2 ubiquitin ligase and associates with active NFY promoters.
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| Costessi A, Mahrour N, Tijchon E, Stunnenberg R, Stoel MA, Jansen PW, Sela D, Martin-Brown S, Washburn MP, Florens L, Conaway JW, Conaway RC, Stunnenberg HG.
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| EMBO J 30(18):3786-98. doi: 10.1038/emboj.2011.262. 2011
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9 | CUL2, CUL5
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| Cullin-5 and cullin-2 play a role in the development of neuromuscular junction and the female germ line of Drosophila.
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| Ayyub C.
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| J Genet. Aug;90(2):239-49. doi: 10.1007/s12041-011-0062-1 2011
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10 | CUL2, CUL5
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| Cullin-5 and cullin-2 play a role in the development of neuromuscular junction and the female germ line of Drosophila.
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| Ayyub C.
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| J Genet. Aug;90(2):239-49. doi: 10.1007/s12041-011-0062-1 2011
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11 | CUL2
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| CUL2 is required for the activity of hypoxia-inducible factor and vasculogenesis.
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| Maeda Y, Suzuki T, Pan X, Chen G, Pan S, Bartman T, Whitsett JA.
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| J Biol Chem 283(23):16084-92. Epub 2008 Mar 27. 2008
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12 | CAND1, CUL1, CUL2, CUL3, CUL4A, CUL4B
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| TIP120A associates with cullins and modulates ubiquitin ligase activity.
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| Min KW, Hwang JW, Lee JS, Park Y, Tamura TA, Yoon JB.
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| J Biol Chem 278(18):15905-10. Epub 2003 Feb 27. 2003
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13 | CUL2, ELOC, HIF1A, VHL
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| Activation of HIF1alpha ubiquitination by a reconstituted von Hippel-Lindau (VHL) tumor suppressor complex.
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| Kamura T, Sato S, Iwai K, Czyzyk-Krzeska M, Conaway RC, Conaway JW.
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| Proc Natl Acad Sci U S A 97(19):10430-5. 2000
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14 | CUL2, VBP1
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| Genomic organization and chromosomal localization of the human CUL2 gene and the role of von hippel-lindau tumor suppressor-binding protein (CUL2 and VBP1) mutation and loss in renal-cell carcinoma development.
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| Clifford SC, et al.
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| Genes Chromosomes Cancer 26(1):20-8. 1999
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15 | CUL2, NEDD8, VHL
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| The von Hippel-Lindau tumor suppressor gene product promotes, but is not essential for, NEDD8 conjugation to cullin-2.
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| Wada H, Yeh ET, Kamitani T.
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| J Biol Chem 274(50):36025-9. 1999
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16 | CUL2, CUL4A, NEDD8
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| Identification of NEDD8-conjugation site in human cullin-2.
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| Wada H, Yeh ET, Kamitani T.
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| Biochem Biophys Res Commun 257(1):100-5. 1999
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17 | CUL2, ELOB, ELOC, VHL
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| Regulation of hypoxia-inducible mRNAs by the von Hippel-Lindau tumor suppressor protein requires binding to complexes containing elongins B/C and Cul2.
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| Lonergan KM, Iliopoulos O, Ohh M, Kamura T, Conaway RC, Conaway JW, Kaelin WG Jr.
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| Mol Cell Biol 18(2):732-41. 1998
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18 | CUL2, VHL
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| The von Hippel-Lindau tumor-suppressor gene product forms a stable complex with human CUL-2, a member of the Cdc53 family of proteins.
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| Pause A, et al.
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| Proc Natl Acad Sci U S A 94 : 2156-2161. 1997
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19 | CUL1, CUL2, CUL3, CUL4A, CUL4B, CUL5
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| cul-1 is required for cell cycle exit in C. elegans and identifies a novel gene family.
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| Kipreos ET, Lander LE, Wing JP, He WW, Hedgecock EM.
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| Cell 85(6):829-39. 1996
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