| 1 | CTSB, CTSS, CTSZ
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| Combined deletion of cathepsin protease family members reveals compensatory mechanisms in cancer.
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| Akkari L, Gocheva V, Quick ML, Kester JC, Spencer AK, Garfall AL, Bowman RL, Joyce JA.
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| Genes Dev 30(2):220-32. doi: 10.1101/gad.270439.115.
2016
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| 2 | CTSZ
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| Distinct functions of macrophage-derived and cancer cell-derived cathepsin Z combine to promote tumor malignancy via interactions with the extracellular matrix.
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| Akkari L, Gocheva V, Kester JC, Hunter KE, Quick ML, Sevenich L, Wang HW, Peters C, Tang LH, Klimstra DS, Reinheckel T, Joyce JA.
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| Genes Dev 28(19):2134-50. doi: 10.1101/gad.249599.114.
2014
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| 3 | CTSZ
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| Characterization of cathepsin X in colorectal cancer development and progression.
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| Jechorek D, Votapek J, Meyer F, Kandulski A, Roessner A, Franke S.
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| Pathol Res Pract 210(12):822-9. doi: 10.1016/j.prp.2014.08.014. Epub 2014 Sep 18.
2014
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| 4 | CTSZ
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| Association of CTSZ rs34069356 and MC3R rs6127698 gene polymorphisms with pulmonary tuberculosis.
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| Hashemi M, Eskandari-Nasab E, Moazeni-Roodi A, Naderi M, Sharifi-Mood B, Taheri M.
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| Int J Tuberc Lung Dis 17(9):1224-8. doi: 10.5588/ijtld.12.0762. Epub 2013 Jul 3.
2013
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| 5 | CTSL, CTSZ
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| Cathepsins L and Z are critical in degrading polyglutamine-containing proteins within lysosomes.
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| Bhutani N, Piccirillo R, Hourez R, Venkatraman P, Goldberg AL.
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| J Biol Chem 287(21):17471-82. doi: 10.1074/jbc.M112.352781. Epub 2012 Mar 27.
2012
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| 6 | CTSZ, MC3R
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| Polymorphisms in MC3R promoter and CTSZ 3'UTR are associated with tuberculosis susceptibility.
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| Adams LA, Möller M, Nebel A, Schreiber S, van der Merwe L, van Helden PD, Hoal EG.
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| Eur J Hum Genet 19(6):676-81. Epub 2011 Feb 2.
2011
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| 7 | CTSZ
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| Cellular senescence induced by cathepsin X downregulation.
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| Kraus S, Bunsen T, Schuster S, Cichoń MA, Tacke M, Reinheckel T, Sommerhoff CP, Jochum M, Nägler DK.
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| Eur J Cell Biol 90(8):678-86. Epub 2011 May 26.
2011
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| 8 | BLMH, CTSZ
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| Cysteine proteases bleomycin hydrolase and cathepsin Z mediate N-terminal proteolysis and toxicity of mutant huntingtin.
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| Ratovitski T, Chighladze E, Waldron E, Hirschhorn RR, Ross CA.
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| J Biol Chem 286(14):12578-89. Epub 2011 Feb 10.
2011
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| 9 | CTSZ, ITGAL, ITGB2
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| Cathepsin X cleavage of the beta2 integrin regulates talin-binding and LFA-1 affinity in T cells.
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| Jevnikar Z, Obermajer N, Doljak B, Turk S, Gobec S, Svajger U, Hailfinger S, Thome M, Kos J.
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| J Leukoc Biol 90(1):99-109. Epub 2011 Mar 31. 2011
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| 10 | CTSB, CTSZ
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| Synergistic antitumor effects of combined cathepsin B and cathepsin Z deficiencies on breast cancer progression and metastasis in mice.
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| Sevenich L, Schurigt U, Sachse K, Gajda M, Werner F, Müller S, Vasiljeva O, Schwinde A, Klemm N, Deussing J, Peters C, Reinheckel T.
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| Proc Natl Acad Sci U S A 107(6):2497-502. Epub 2010 Jan 21.
2010
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| 11 | CTSZ, ITGB2
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| Cathepsin X cleaves the beta2 cytoplasmic tail of LFA-1 inducing the intermediate affinity form of LFA-1 and alpha-actinin-1 binding.
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| Jevnikar Z, Obermajer N, Pecar-Fonović U, Karaoglanovic-Carmona A, Kos J.
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| Eur J Immunol 39(11):3217-27.
2009
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| 12 | CTSZ, MC3R
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| Mapping of a novel susceptibility locus suggests a role for MC3R and CTSZ in human tuberculosis.
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| Cooke GS, Campbell SJ, Bennett S, Lienhardt C, McAdam KP, Sirugo G, Sow O, Gustafson P, Mwangulu F, van Helden P, Fine P, Hoal EG, Hill AV.
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| Am J Respir Crit Care Med 178(2):203-7. Epub 2008 Apr 17. Erratum in: Am J Respir Crit Care Med. 2009 Apr 1;179(7):624.
2008
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| 13 | CTSZ
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| RGD-dependent binding of procathepsin X to integrin alphavbeta3 mediates cell-adhesive properties.
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| Lechner AM, Assfalg-Machleidt I, Zahler S, Stoeckelhuber M, Machleidt W, Jochum M, Nägler DK.
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| J Biol Chem 281(51):39588-97. Epub 2006 Oct 25.
2006
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| 14 | CTSL, CTSZ
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| Recombinant human cathepsin X is a carboxymonopeptidase only: a comparison with cathepsins B and L.
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| Puzer L, Cotrin SS, Cezari MH, Hirata IY, Juliano MA, Stefe I, Turk D, Turk B, Juliano L, Carmona AK.
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| Biol Chem 386(11):1191-5. 2005
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| 15 | CTSZ, GNAS, TH1L
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| Characterization of TH1 and CTSZ, two non-imprinted genes downstream of GNAS1 in chromosome 20q13.
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| Bonthron DT, Hayward BE, Moran V, Strain L.
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| Hum Genet 107(2):165-75. 2000
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| 16 | CTSZ
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| Murine and human cathepsin Z: cDNA-cloning, characterization of the genes and chromosomal localization.
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| Deussing J, von Olshausen I, Peters C.
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| Biochim Biophys Acta 1491(1-3):93-106. 2000
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| 17 | CTSZ
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| Human cathepsin X: A cysteine protease with unique carboxypeptidase activity.
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| Nagler DK, Zhang R, Tam W, Sulea T, Purisima EO, Menard R.
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| Biochemistry 38(39):12648-54. 1999
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| 18 | CTSZ
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| Cathepsin Z, a novel human cysteine proteinase with a short propeptide domain and a unique chromosomal location.
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| Santamaria I, et al.
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| J Biol Chem 273 : 16816-16823. 1998
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| 19 | CTSZ
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| Human cathepsin X: a novel cysteine protease of the papain family with a very short proregion and unique insertions.
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| Nagler DK, Menard R.
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| FEBS Lett 434(1-2):135-9. 1998
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