Citations for
1CTSB, CTSS, CTSZ
Combined deletion of cathepsin protease family members reveals compensatory mechanisms in cancer.
Akkari L, Gocheva V, Quick ML, Kester JC, Spencer AK, Garfall AL, Bowman RL, Joyce JA.
Genes Dev 30(2):220-32. doi: 10.1101/gad.270439.115. 2016
2CTSS
Cathepsin S silencing induces apoptosis of human hepatocellular carcinoma cells.
Wang X, Xiong L, Yu G, Li D, Peng T, Luo D, Xu J.
Am J Transl Res 7(1):100-10. eCollection 2015. 2015
3CTSS, LRP1
Cardiomyocyte intracellular cholesteryl ester accumulation promotes tropoelastin physical alteration and degradation: Role of LRP1 and cathepsin S.
Samouillan V, Revuelta-López E, Dandurand J, Nasarre L, Badimon L, Lacabanne C, Llorente-Cortés V.
Int J Biochem Cell Biol 55:209-19. doi: 10.1016/j.biocel.2014.09.005. Epub 2014 Sep 16. 2014
4CTSS, F2RL1
Cathepsin S causes inflammatory pain via biased agonism of PAR2 and TRPV4.
Zhao P, Lieu T, Barlow N, Metcalf M, Veldhuis NA, Jensen DD, Kocan M, Sostegni S, Haerteis S, Baraznenok V, Henderson I, Lindström E, Guerrero-Alba R, Valdez-Morales EE, Liedtke W, McIntyre P, Vanner SJ, Korbmacher C, Bunnett NW.
J Biol Chem 289(39):27215-34. doi: 10.1074/jbc.M114.599712. Epub 2014 Aug 12. Erratum in: J Biol Chem. 2014 Dec 26;289(52):35858. 2014
5CTSS
Cathepsin S controls adipocytic and osteoblastic differentiation, bone turnover, and bone microarchitecture.
Rauner M, Föger-Samwald U, Kurz MF, Brünner-Kubath C, Schamall D, Kapfenberger A, Varga P, Kudlacek S, Wutzl A, Höger H, Zysset PK, Shi GP, Hofbauer LC, Sipos W, Pietschmann P.
Bone 64:281-7. doi: 10.1016/j.bone.2014.04.022. Epub 2014 Apr 26. 2014
6CTSS
Cathepsin S-mediated autophagic flux in tumor-associated macrophages accelerate tumor development by promoting M2 polarization.
Yang M, Liu J, Shao J, Qin Y, Ji Q, Zhang X, Du J.
Mol Cancer 13:43. doi: 10.1186/1476-4598-13-43. 2014
7CTSS
Tear cathepsin S as a candidate biomarker for Sjögren's syndrome.
Hamm-Alvarez SF, Janga SR, Edman MC, Madrigal S, Shah M, Frousiakis SE, Renduchintala K, Zhu J, Bricel S, Silka K, Bach D, Heur M, Christianakis S, Arkfeld DG, Irvine J, Mack WJ, Stohl W.
Arthritis Rheumatol 66(7):1872-81. doi: 10.1002/art.38633. 2014
8CTSS
Peripheral role of cathepsin S in Th1 cell-dependent transition of nerve injury-induced acute pain to a chronic pain state.
Zhang X, Wu Z, Hayashi Y, Okada R, Nakanishi H.
J Neurosci 34(8):3013-22. doi: 10.1523/JNEUROSCI.3681-13.2014. 2014
9CTSS, IFI30
γ-Interferon-inducible lysosomal thiol reductase (GILT) maintains phagosomal proteolysis in alternatively activated macrophages.
Balce DR, Allan ER, McKenna N, Yates RM.
J Biol Chem 289(46):31891-904. doi: 10.1074/jbc.M114.584391. Epub 2014 Sep 24. 2014
10CTSS
The intrinsic microglial molecular clock controls synaptic strength via the circadian expression of cathepsin S.
Hayashi Y, Koyanagi S, Kusunose N, Okada R, Wu Z, Tozaki-Saitoh H, Ukai K, Kohsaka S, Inoue K, Ohdo S, Nakanishi H.
Sci Rep 3:2744. doi: 10.1038/srep02744. 2013
11CTSS, IFI30
GILT expression in B cells diminishes cathepsin S steady-state protein expression and activity.
Phipps-Yonas H, Semik V, Hastings KT.
Eur J Immunol 43(1):65-74. doi: 10.1002/eji.201242379. Epub 2012 Nov 26. 2013
12CTSS
The proinflammatory cytokines interleukin-1α and tumor necrosis factor α promote the expression and secretion of proteolytically active cathepsin S from human chondrocytes.
Caglič D, Repnik U, Jedeszko C, Kosec G, Miniejew C, Kindermann M, Vasiljeva O, Turk V, Wendt KU, Sloane BF, Goldring MB, Turk B.
Biol Chem 394(2):307-16. doi: 10.1515/hsz-2012-0283. 2013
13CTSS
Cathepsin S from both tumor and tumor-associated cells promote cancer growth and neovascularization.
Small DM, Burden RE, Jaworski J, Hegarty SM, Spence S, Burrows JF, McFarlane C, Kissenpfennig A, McCarthy HO, Johnston JA, Walker B, Scott CJ.
Int J Cancer 133(9):2102-12. doi: 10.1002/ijc.28238. Epub 2013 May 29. 2013
14CTSK, CTSS
Cathepsin S cannibalism of cathepsin K as a mechanism to reduce type I collagen degradation.
Barry ZT, Platt MO.
J Biol Chem 287(33):27723-30. doi: 10.1074/jbc.M111.332684. Epub 2012 Jun 22. 2012
15CTSS
Cleavage of nidogen-1 by cathepsin S impairs its binding to basement membrane partners.
Sage J, Leblanc-Noblesse E, Nizard C, Sasaki T, Schnebert S, Perrier E, Kurfurst R, Brömme D, Lalmanach G, Lecaille F.
PLoS One 7(8):e43494. doi: 10.1371/journal.pone.0043494. Epub 2012 Aug 28. 2012
16CTSB, CTSK, CTSL, CTSS
Cysteine cathepsin S processes leptin, inactivating its biological activity.
Oliveira M, Assis DM, Paschoalin T, Miranda A, Ribeiro EB, Juliano MA, Brömme D, Christoffolete MA, Barros NM, Carmona AK.
J Endocrinol 214(2):217-24. doi: 10.1530/JOE-12-0108. Epub 2012 May 31. 2012
17CTSS
Cathepsin S deficiency results in abnormal accumulation of autophagosomes in macrophages and enhances Ang II-induced cardiac inflammation.
Pan L, Li Y, Jia L, Qin Y, Qi G, Cheng J, Qi Y, Li H, Du J.
PLoS One 7(4):e35315. doi: 10.1371/journal.pone.0035315. Epub 2012 Apr 30. 2012
18CTSS
Silencing cathepsin S gene expression inhibits growth, invasion and angiogenesis of human hepatocellular carcinoma in vitro.
Fan Q, Wang X, Zhang H, Li C, Fan J, Xu J.
Biochem Biophys Res Commun 425(4):703-10. doi: 10.1016/j.bbrc.2012.07.013. 2012
19CTSB, CTSS
Cathepsins (S and B) and their inhibitor Cystatin C in immune cells: modulation by interferon-β and role played in cell migration.
Staun-Ram E, Miller A.
J Neuroimmunol 232(1-2):200-6. doi: 10.1016/j.jneuroim.2010.10.015. Epub 2010 Nov 26. 2011
20CTSK, CTSL, CTSS
Cathepsins in human obesity: changes in energy balance predominantly affect cathepsin s in adipose tissue and in circulation.
Naour N, Rouault C, Fellahi S, Lavoie ME, Poitou C, Keophiphath M, Eberlé D, Shoelson S, Rizkalla S, Bastard JP, Rabasa-Lhoret R, Clément K, Guerre-Millo M.
J Clin Endocrinol Metab 95(4):1861-8. Epub 2010 Feb 17. 2010
21CTSS
Upregulation of cathepsin S in psoriatic keratinocytes.
Schönefuss A, Wendt W, Schattling B, Schulten R, Hoffmann K, Stuecker M, Tigges C, Lübbert H, Stichel C.
Exp Dermatol 19(8):e80-8. doi: 10.1111/j.1600-0625.2009.00990.x. 2010
22CTSH, CTSS
Levels of cathepsins S and H in pleural fluids of inflammatory and neoplastic origin.
Bunatova K, Obermajer N, Kotyza J, Pesek M, Kos J.
Int J Biol Markers 24(1):47-51. 2009
23CTSS
Cathepsin S genotypes are associated with Apo-A1 and HDL-cholesterol in lean and obese French populations.
Spielmann N, Mutch DM, Rousseau F, Tores F, Hager J, Bertrais S, Basdevant A, Tounian P, Dubern B, Galan P, Clément K.
Clin Genet 74(2):155-63. Epub 2008 Jun 28. 2008
24CTSS
Cathepsin S controls angiogenesis and tumor growth via matrix-derived angiogenic factors.
Wang B, Sun J, Kitamoto S, Yang M, Grubb A, Chapman HA, Kalluri R, Shi GP.
J Biol Chem 281(9):6020-9. Epub 2005 Dec 19. 2006
25CTSS, NEB, NEM2
Cathepsin s promotes human preadipocyte differentiation: possible involvement of fibronectin degradation.
Taleb S, Cancello R, ClŽment K, Lacasa D.
Endocrinology 147(10):4950-9. Epub 2006 Jul 6. 2006
26CTSS
Specific role for cathepsin S in the generation of antigenic peptides in vivo.
Pluger EB, Boes M, Alfonso C, Schroter CJ, Kalbacher H, Ploegh HL, Driessen C.
Eur J Immunol 32(2):467-76. 2002
27CTSS
Cathepsin S inhibitor prevents autoantigen presentation and autoimmunity.
Saegusa K, Ishimaru N, Yanagi K, Arakaki R, Ogawa K, Saito I, Katunuma N, Hayashi Y.
J Clin Invest 110(3):361-9. 2002
28CTSS
Cathepsin S in tumours, regional lymph nodes and sera of patients with lung cancer: relation to prognosis.
Kos J, Sekirnik A, Kopitar G, Cimerman N, Kayser K, Stremmer A, Fiehn W, Werle B.
Br J Cancer 85(8):1193-200. 2001
29CTSS
Human cathepsin S gene (CTSS) promoter -25G/A polymorphism.
Cao H, Hegele RA.
J Hum Genet 45(2):94-5. 2000
30CTSS
Essential role for cathepsin S in MHC class II-associated invariant chain processing and peptide loading.
Riese RJ, et al.
Immunity 4 : 357-366. 1996
31CTSS
Human cathepsin S : chromosomal localization, gene structure, and tissue distribution.
Shi GP, et al.
J Biol Chem 269 : 11530-11536. 1994
32CTSS
Molecular cloning and expression of human alveolar macrophage cathepsin S, an elastinolytic cysteine protease.
Shi GP, Munger JS, Meara JP, Rich DH, Chapman HA.
J Biol Chem 267(11):7258-62. 1992
33CTSS
Phylogenetic conservation of cysteine proteinases. Cloning and expression of a cDNA coding for human cathepsin S.
Wiederanders B, Bromme D, Kirschke H, von Figura K, Schmidt B, Peters C.
J Biol Chem 267(19):13708-13. 1992