1 | CTSS, RAB27A
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| Rab27a Contributes to Cathepsin S Secretion in Lacrimal Gland Acinar Cells.
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| Fu R, Edman MC, Hamm-Alvarez SF.
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| Int J Mol Sci. Feb 5;22(4):1630. doi: 10.3390/ijms22041630. 2021
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2 | CTSB, CTSS, CTSZ
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| Combined deletion of cathepsin protease family members reveals compensatory mechanisms in cancer.
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| Akkari L, Gocheva V, Quick ML, Kester JC, Spencer AK, Garfall AL, Bowman RL, Joyce JA.
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| Genes Dev 30(2):220-32. doi: 10.1101/gad.270439.115.
2016
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3 | CTSS
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| Cathepsin S silencing induces apoptosis of human hepatocellular carcinoma cells.
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| Wang X, Xiong L, Yu G, Li D, Peng T, Luo D, Xu J.
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| Am J Transl Res 7(1):100-10. eCollection 2015.
2015
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4 | CTSS, LRP1
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| Cardiomyocyte intracellular cholesteryl ester accumulation promotes tropoelastin physical alteration and degradation: Role of LRP1 and cathepsin S.
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| Samouillan V, Revuelta-López E, Dandurand J, Nasarre L, Badimon L, Lacabanne C, Llorente-Cortés V.
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| Int J Biochem Cell Biol 55:209-19. doi: 10.1016/j.biocel.2014.09.005. Epub 2014 Sep 16.
2014
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5 | CTSS, F2RL1
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| Cathepsin S causes inflammatory pain via biased agonism of PAR2 and TRPV4.
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| Zhao P, Lieu T, Barlow N, Metcalf M, Veldhuis NA, Jensen DD, Kocan M, Sostegni S, Haerteis S, Baraznenok V, Henderson I, Lindström E, Guerrero-Alba R, Valdez-Morales EE, Liedtke W, McIntyre P, Vanner SJ, Korbmacher C, Bunnett NW.
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| J Biol Chem 289(39):27215-34. doi: 10.1074/jbc.M114.599712. Epub 2014 Aug 12. Erratum in: J Biol Chem. 2014 Dec 26;289(52):35858.
2014
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6 | CTSS
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| Cathepsin S controls adipocytic and osteoblastic differentiation, bone turnover, and bone microarchitecture.
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| Rauner M, Föger-Samwald U, Kurz MF, Brünner-Kubath C, Schamall D, Kapfenberger A, Varga P, Kudlacek S, Wutzl A, Höger H, Zysset PK, Shi GP, Hofbauer LC, Sipos W, Pietschmann P.
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| Bone 64:281-7. doi: 10.1016/j.bone.2014.04.022. Epub 2014 Apr 26.
2014
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7 | CTSS
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| Cathepsin S-mediated autophagic flux in tumor-associated macrophages accelerate tumor development by promoting M2 polarization.
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| Yang M, Liu J, Shao J, Qin Y, Ji Q, Zhang X, Du J.
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| Mol Cancer 13:43. doi: 10.1186/1476-4598-13-43.
2014
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8 | CTSS
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| Tear cathepsin S as a candidate biomarker for Sjögren's syndrome.
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| Hamm-Alvarez SF, Janga SR, Edman MC, Madrigal S, Shah M, Frousiakis SE, Renduchintala K, Zhu J, Bricel S, Silka K, Bach D, Heur M, Christianakis S, Arkfeld DG, Irvine J, Mack WJ, Stohl W.
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| Arthritis Rheumatol 66(7):1872-81. doi: 10.1002/art.38633.
2014
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9 | CTSS
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| Peripheral role of cathepsin S in Th1 cell-dependent transition of nerve injury-induced acute pain to a chronic pain state.
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| Zhang X, Wu Z, Hayashi Y, Okada R, Nakanishi H.
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| J Neurosci 34(8):3013-22. doi: 10.1523/JNEUROSCI.3681-13.2014.
2014
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10 | CTSS, IFI30
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| γ-Interferon-inducible lysosomal thiol reductase (GILT) maintains phagosomal proteolysis in alternatively activated macrophages.
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| Balce DR, Allan ER, McKenna N, Yates RM.
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| J Biol Chem 289(46):31891-904. doi: 10.1074/jbc.M114.584391. Epub 2014 Sep 24.
2014
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11 | CTSS
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| The intrinsic microglial molecular clock controls synaptic strength via the circadian expression of cathepsin S.
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| Hayashi Y, Koyanagi S, Kusunose N, Okada R, Wu Z, Tozaki-Saitoh H, Ukai K, Kohsaka S, Inoue K, Ohdo S, Nakanishi H.
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| Sci Rep 3:2744. doi: 10.1038/srep02744.
2013
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12 | CTSS, IFI30
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| GILT expression in B cells diminishes cathepsin S steady-state protein expression and activity.
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| Phipps-Yonas H, Semik V, Hastings KT.
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| Eur J Immunol 43(1):65-74. doi: 10.1002/eji.201242379. Epub 2012 Nov 26.
2013
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13 | CTSS
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| The proinflammatory cytokines interleukin-1α and tumor necrosis factor α promote the expression and secretion of proteolytically active cathepsin S from human chondrocytes.
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| Caglič D, Repnik U, Jedeszko C, Kosec G, Miniejew C, Kindermann M, Vasiljeva O, Turk V, Wendt KU, Sloane BF, Goldring MB, Turk B.
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| Biol Chem 394(2):307-16. doi: 10.1515/hsz-2012-0283.
2013
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14 | CTSS
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| Cathepsin S from both tumor and tumor-associated cells promote cancer growth and neovascularization.
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| Small DM, Burden RE, Jaworski J, Hegarty SM, Spence S, Burrows JF, McFarlane C, Kissenpfennig A, McCarthy HO, Johnston JA, Walker B, Scott CJ.
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| Int J Cancer 133(9):2102-12. doi: 10.1002/ijc.28238. Epub 2013 May 29.
2013
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15 | CTSK, CTSS
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| Cathepsin S cannibalism of cathepsin K as a mechanism to reduce type I collagen degradation.
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| Barry ZT, Platt MO.
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| J Biol Chem 287(33):27723-30. doi: 10.1074/jbc.M111.332684. Epub 2012 Jun 22.
2012
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16 | CTSS
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| Cleavage of nidogen-1 by cathepsin S impairs its binding to basement membrane partners.
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| Sage J, Leblanc-Noblesse E, Nizard C, Sasaki T, Schnebert S, Perrier E, Kurfurst R, Brömme D, Lalmanach G, Lecaille F.
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| PLoS One 7(8):e43494. doi: 10.1371/journal.pone.0043494. Epub 2012 Aug 28.
2012
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17 | CTSB, CTSK, CTSL, CTSS
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| Cysteine cathepsin S processes leptin, inactivating its biological activity.
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| Oliveira M, Assis DM, Paschoalin T, Miranda A, Ribeiro EB, Juliano MA, Brömme D, Christoffolete MA, Barros NM, Carmona AK.
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| J Endocrinol 214(2):217-24. doi: 10.1530/JOE-12-0108. Epub 2012 May 31.
2012
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18 | CTSS
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| Cathepsin S deficiency results in abnormal accumulation of autophagosomes in macrophages and enhances Ang II-induced cardiac inflammation.
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| Pan L, Li Y, Jia L, Qin Y, Qi G, Cheng J, Qi Y, Li H, Du J.
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| PLoS One 7(4):e35315. doi: 10.1371/journal.pone.0035315. Epub 2012 Apr 30.
2012
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19 | CTSS
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| Silencing cathepsin S gene expression inhibits growth, invasion and angiogenesis of human hepatocellular carcinoma in vitro.
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| Fan Q, Wang X, Zhang H, Li C, Fan J, Xu J.
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| Biochem Biophys Res Commun 425(4):703-10. doi: 10.1016/j.bbrc.2012.07.013.
2012
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20 | CTSB, CTSS
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| Cathepsins (S and B) and their inhibitor Cystatin C in immune cells: modulation by interferon-β and role played in cell migration.
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| Staun-Ram E, Miller A.
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| J Neuroimmunol 232(1-2):200-6. doi: 10.1016/j.jneuroim.2010.10.015. Epub 2010 Nov 26.
2011
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21 | CTSK, CTSL, CTSS
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| Cathepsins in human obesity: changes in energy balance predominantly affect cathepsin s in adipose tissue and in circulation.
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| Naour N, Rouault C, Fellahi S, Lavoie ME, Poitou C, Keophiphath M, Eberlé D, Shoelson S, Rizkalla S, Bastard JP, Rabasa-Lhoret R, Clément K, Guerre-Millo M.
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| J Clin Endocrinol Metab 95(4):1861-8. Epub 2010 Feb 17. 2010
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22 | CTSS
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| Upregulation of cathepsin S in psoriatic keratinocytes.
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| Schönefuss A, Wendt W, Schattling B, Schulten R, Hoffmann K, Stuecker M, Tigges C, Lübbert H, Stichel C.
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| Exp Dermatol 19(8):e80-8. doi: 10.1111/j.1600-0625.2009.00990.x.
2010
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23 | CTSH, CTSS
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| Levels of cathepsins S and H in pleural fluids of inflammatory and neoplastic origin.
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| Bunatova K, Obermajer N, Kotyza J, Pesek M, Kos J.
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| Int J Biol Markers 24(1):47-51.
2009
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24 | CTSS
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| Cathepsin S genotypes are associated with Apo-A1 and HDL-cholesterol in lean and obese French populations.
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| Spielmann N, Mutch DM, Rousseau F, Tores F, Hager J, Bertrais S, Basdevant A, Tounian P, Dubern B, Galan P, Clément K.
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| Clin Genet 74(2):155-63. Epub 2008 Jun 28.
2008
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25 | CTSS
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| Cathepsin S controls angiogenesis and tumor growth via matrix-derived angiogenic factors.
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| Wang B, Sun J, Kitamoto S, Yang M, Grubb A, Chapman HA, Kalluri R, Shi GP.
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| J Biol Chem 281(9):6020-9. Epub 2005 Dec 19. 2006
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26 | CTSS, NEB, NEM2
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| Cathepsin s promotes human preadipocyte differentiation: possible involvement of fibronectin degradation.
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| Taleb S, Cancello R, Clment K, Lacasa D.
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| Endocrinology 147(10):4950-9. Epub 2006 Jul 6. 2006
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27 | CTSS
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| Specific role for cathepsin S in the generation of antigenic peptides in vivo.
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| Pluger EB, Boes M, Alfonso C, Schroter CJ, Kalbacher H, Ploegh HL, Driessen C.
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| Eur J Immunol 32(2):467-76. 2002
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28 | CTSS
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| Cathepsin S inhibitor prevents autoantigen presentation and autoimmunity.
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| Saegusa K, Ishimaru N, Yanagi K, Arakaki R, Ogawa K, Saito I, Katunuma N, Hayashi Y.
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| J Clin Invest 110(3):361-9. 2002
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29 | CTSS
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| Cathepsin S in tumours, regional lymph nodes and sera of patients with lung cancer: relation to prognosis.
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| Kos J, Sekirnik A, Kopitar G, Cimerman N, Kayser K, Stremmer A, Fiehn W, Werle B.
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| Br J Cancer 85(8):1193-200. 2001
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30 | CTSS
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| Human cathepsin S gene (CTSS) promoter -25G/A polymorphism.
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| Cao H, Hegele RA.
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| J Hum Genet 45(2):94-5. 2000
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31 | CTSS
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| Essential role for cathepsin S in MHC class II-associated invariant chain processing and peptide loading.
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| Riese RJ, et al.
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| Immunity 4 : 357-366. 1996
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32 | CTSS
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| Human cathepsin S : chromosomal localization, gene structure, and tissue distribution.
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| Shi GP, et al.
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| J Biol Chem 269 : 11530-11536. 1994
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33 | CTSS
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| Molecular cloning and expression of human alveolar macrophage cathepsin S, an elastinolytic cysteine protease.
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| Shi GP, Munger JS, Meara JP, Rich DH, Chapman HA.
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| J Biol Chem 267(11):7258-62. 1992
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34 | CTSS
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| Phylogenetic conservation of cysteine proteinases. Cloning and expression of a cDNA coding for human cathepsin S.
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| Wiederanders B, Bromme D, Kirschke H, von Figura K, Schmidt B, Peters C.
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| J Biol Chem 267(19):13708-13. 1992
|