Citations for
1CTSK
Cathepsin K Contributes to Cavitation and Collagen Turnover in Pulmonary Tuberculosis.
Kubler A, Larsson C, Luna B, Andrade BB, Amaral EP, Urbanowski M, Orandle M, Bock K, Ammerman NC, Cheung LS, Winglee K, Halushka M, Park JK, Sher A, Friedland JS, Elkington PT, Bishai WR.
J Infect Dis Infect Dis. 2015 Sep 27. pii: jiv458. [Epub ahead of print] 2015
2CTSK, MMP9
Matrix-metalloproteinase-9 is cleaved and activated by cathepsin K.
Christensen J, Shastri VP.
BMC Res Notes 8:322. doi: 10.1186/s13104-015-1284-8. 2015
3CTSK
Deficiency of cathepsin K prevents inflammation and bone erosion in rheumatoid arthritis and periodontitis and reveals its shared osteoimmune role.
Hao L, Zhu G, Lu Y, Wang M, Jules J, Zhou X, Chen W.
FEBS Lett 589(12):1331-9. doi: 10.1016/j.febslet.2015.04.008. Epub 2015 Apr 17. 2015
4CTSK
Structural basis of collagen fiber degradation by cathepsin K.
Aguda AH, Panwar P, Du X, Nguyen NT, Brayer GD, Brömme D.
Proc Natl Acad Sci U S A 111(49):17474-9. doi: 10.1073/pnas.1414126111. Epub 2014 Nov 24. 2014
5CTSK
Increased fracture callus mineralization and strength in cathepsin K knockout mice.
Gentile MA, Soung do Y, Horrell C, Samadfam R, Drissi H, Duong LT.
Bone 66:72-81. doi: 10.1016/j.bone.2014.04.032. Epub 2014 Jun 10. Erratum in: Bone. 2015 Feb;71:264. 2014
6CTSK, PYCD
Cathepsin K analysis in a pycnodysostosis cohort: demographic, genotypic and phenotypic features.
Arman A, Bereket A, Coker A, Kiper PÖ, Güran T, Ozkan B, Atay Z, Akçay T, Haliloglu B, Boduroglu K, Alanay Y, Turan S.
Orphanet J Rare Dis 9:60. doi: 10.1186/1750-1172-9-60. 2014
7CTSK
Exome sequencing identifies CTSK mutations in patients originally diagnosed as intermediate osteopetrosis.
Pangrazio A, Puddu A, Oppo M, Valentini M, Zammataro L, Vellodi A, Gener B, Llano-Rivas I, Raza J, Atta I, Vezzoni P, Superti-Furga A, Villa A, Sobacchi C.
Bone 59:122-6. doi: 10.1016/j.bone.2013.11.014. Epub 2013 Nov 20. 2014
8CTSK
Cathepsin K knockout alleviates pressure overload-induced cardiac hypertrophy.
Hua Y, Xu X, Shi GP, Chicco AJ, Ren J, Nair S.
Hypertension 61(6):1184-92. doi: 10.1161/HYPERTENSIONAHA.111.00947. Epub 2013 Mar 25. 2013
9CTSK
Osteoclast-specific cathepsin K deletion stimulates S1P-dependent bone formation.
Lotinun S, Kiviranta R, Matsubara T, Alzate JA, Neff L, Lüth A, Koskivirta I, Kleuser B, Vacher J, Vuorio E, Horne WC, Baron R.
J Clin Invest 123(2):666-81. doi: 10.1172/JCI64840. Epub 2013 Jan 16. 2013
10CTSK, MARCKS, PRKCD
Protein kinase C-delta deficiency perturbs bone homeostasis by selective uncoupling of cathepsin K secretion and ruffled border formation in osteoclasts.
Cremasco V, Decker CE, Stumpo D, Blackshear PJ, Nakayama KI, Nakayama K, Lupu TS, Graham DB, Novack DV, Faccio R.
J Bone Miner Res 27(12):2452-63. doi: 10.1002/jbmr.1701. 2012
11CTSK, CTSS
Cathepsin S cannibalism of cathepsin K as a mechanism to reduce type I collagen degradation.
Barry ZT, Platt MO.
J Biol Chem 287(33):27723-30. doi: 10.1074/jbc.M111.332684. Epub 2012 Jun 22. 2012
12CLU, CTSK
Clusterin is a specific stabilizer and liberator of extracellular cathepsin K.
Novinec M, Lenarčič B, Baici A.
FEBS Lett 586(7):1062-6. doi: 10.1016/j.febslet.2012.03.004. Epub 2012 Mar 10. 2012
13CTSK
Cathepsin K deficiency reduces elastase perfusion-induced abdominal aortic aneurysms in mice.
Sun J, Sukhova GK, Zhang J, Chen H, Sjöberg S, Libby P, Xia M, Xiong N, Gelb BD, Shi GP.
Arterioscler Thromb Vasc Biol 32(1):15-23. doi: 10.1161/ATVBAHA.111.235002. Epub 2011 Aug 4. 2012
14CTSB, CTSK, CTSL, CTSS
Cysteine cathepsin S processes leptin, inactivating its biological activity.
Oliveira M, Assis DM, Paschoalin T, Miranda A, Ribeiro EB, Juliano MA, Brömme D, Christoffolete MA, Barros NM, Carmona AK.
J Endocrinol 214(2):217-24. doi: 10.1530/JOE-12-0108. Epub 2012 May 31. 2012
15CTSK
Structure-activity analysis of cathepsin K/chondroitin 4-sulfate interactions.
Cherney MM, Lecaille F, Kienitz M, Nallaseth FS, Li Z, James MN, Brömme D.
J Biol Chem 286(11):8988-98. Epub 2010 Dec 30. 2011
16CTSK, SIGLEC15
Siglec-15, a member of the sialic acid-binding lectin, is a novel regulator for osteoclast differentiation.
Hiruma Y, Hirai T, Tsuda E.
Biochem Biophys Res Commun 409(3):424-9. Epub 2011 May 8. 2011
17CTSK, CTSL, CTSS
Cathepsins in human obesity: changes in energy balance predominantly affect cathepsin s in adipose tissue and in circulation.
Naour N, Rouault C, Fellahi S, Lavoie ME, Poitou C, Keophiphath M, Eberlé D, Shoelson S, Rizkalla S, Bastard JP, Rabasa-Lhoret R, Clément K, Guerre-Millo M.
J Clin Endocrinol Metab 95(4):1861-8. Epub 2010 Feb 17. 2010
18CTSK
Cathepsin K activity-dependent regulation of osteoclast actin ring formation and bone resorption.
Wilson SR, Peters C, Saftig P, Brömme D.
J Biol Chem 284(4):2584-92. Epub 2008 Nov 21. 2009
19CTSK, PYCD
Cathepsin K: a therapeutic target for bone diseases.
Zhao Q, Jia Y, Xiao Y.
Biochem Biophys Res Commun 380(4):721-3. Epub 2009 Jan 27. Review. 2009
20CTSK, NFATC1, TNFSF11
Identification of NFAT binding sites that mediate stimulation of cathepsin K promoter activity by RANK ligand.
Balkan W, Martinez AF, Fernandez I, Rodriguez MA, Pang M, Troen BR.
Gene 446(2):90-8. Epub 2009 Jun 27. 2009
21CTSK
Cathepsin K inhibitors prevent matrix-derived growth factor degradation by human osteoclasts.
Fuller K, Lawrence KM, Ross JL, Grabowska UB, Shiroo M, Samuelsson B, Chambers TJ.
Bone 42(1):200-11. Epub 2007 Sep 26.PMID: 17962093 2008
22CTSK
Cathepsin K in melanoma invasion.
Quintanilla-Dieck MJ, Codriansky K, Keady M, Bhawan J, Rünger TM.
J Invest Dermatol 128(9):2281-8. Epub 2008 Mar 27. 2008
23CTSK, PYCD
Novel pycnodysostosis mouse model uncovers cathepsin K function as a potential regulator of osteoclast apoptosis and senescence.
Chen W, Yang S, Abe Y, Li M, Wang Y, Shao J, Li E, Li YP.
Hum Mol Genet 16(4):410-23. Epub 2007 Jan 8. 2007
24CTSK
Role of cathepsin K in the turnover of the dermal extracellular matrix during scar formation.
Runger TM, Quintanilla-Dieck MJ, Bhawan J.
J Invest Dermatol 127(2):293-7. Epub 2006 Aug 31. 2007
25CTSK
The regulation of cathepsin K gene expression.
Troen BR.
Ann N Y Acad Sci 1068:165-72. Review. 2006
26CTSK
Human osteoblasts produce cathepsin K.
Mandelin J, Hukkanen M, Li TF, Korhonen M, Liljestrom M, Sillat T, Hanemaaijer R, Salo J, Santavirta S, Konttinen YT.
Bone 38(6):769-77. Epub 2005 Dec 5. 2006
27NFATC1, TNFSF11, CTSK
NFATc1 expression in the developing heart valves is responsive to the RANKL pathway and is required for endocardial expression of cathepsin K.
Lange AW, Yutzey KE.
Dev Biol 292(2):407-17. 2006
28CTSK
Cathepsin K mRNA and protein expression in prostate cancer progression.
Brubaker KD, Vessella RL, True LD, Thomas R, Corey E.
J Bone Miner Res 18(2):222-30. 2003
29CTSK
Cathepsin k is a critical protease in synovial fibroblast-mediated collagen degradation.
Hou WS, Li Z, Gordon RE, Chan K, Klein MJ, Levy R, Keysser M, Keyszer G, Bromme D.
Am J Pathol 159(6):2167-77. 2001
30CTSK
Novel mutations of the cathepsin K gene in patients with pycnodysostosis and their characterization.
Fujita Y, Nakata K, Yasui N, Matsui Y, Kataoka E, Hiroshima K, Shiba RI, Ochi T.
J Clin Endocrinol Metab 85(1):425-31. 2000
31CTSK, PYCD
Characterization of novel cathepsin K mutations in the pro and mature polypeptide regions causing pycnodysostosis.
Hou WS, et al.
J Clin Invest 103(5):731-8. 1999
32CTSB, CTSH, CTSK, CTSL
Cathepsin expression during skeletal development.
Soderstrom M, et al.
Biochim Biophys Acta 1446(1-2):35-46 1999
33CTSK, PYCD
Mutations of CTSK result in pycnodysostosis via a reduction in cathepsin K protein.
Ho N, Punturieri A, Wilkin D, Szabo J, Johnson M, Whaley J, Davis J, Clark A, Weiss S, Francomano C.
J Bone Miner Res 14(10):1649-53 1999
34CTSK
Impaired osteoclastic bone resorption leads to osteopetrosis in cathepsin-K-deficient mice.
Saftig P, et al.
Proc Natl Acad Sci U S A 95 : 13453-13458. 1998
35CTSK
Genomic organization and chromosome localization of the human cathepsin K gene (CTSK).
Rood JA, Van Horn S, Drake FH, Gowen M, Debouck C.
Genomics 41 : 169-176. 1997
36CTSK
Structure and chromosomal assignment of the human cathepsin K gene.
Gelb BD, Shi GP, Heller M, Weremowicz S, Morton C, Desnick RJ, Chapman HA.
Genomics 41 : 258-262. 1997
37PYCD, CTSK
Pycnodysostosis, a lysosomal disease caused by cathepsin K deficiency.
Gelb BD, Shi GP, Chapman HA, Desnick RJ.
Science 273 : 1236-1238. 1996
38CTSK, PYCD
A nonsense mutation in the cathepsin K gene observed in a family with pycnodysostosis.
Johnson MR, Polymeropoulos MH, Vos HL, Ortiz de Luna RI, Francomano CA.
Genome Res 6 : 1050 -1055. 1996
39CTSK
Human cathepsin O2, a novel cysteine protease highly expressed in osteoclastomas and ovary molecular cloning, sequencing and tissue distribution.
Bromme D, Okamoto K.
Biol Chem Hoppe Seyler 376(6):379-84. 1995
40CTSK
Cloning and complete coding sequence of a novel human cathepsin expressed in giant cells of osteoclastomas.
Li YP, Alexander M, Wucherpfennig AL, Yelick P, Chen W, Stashenko P.
J Bone Miner Res 10(8):1197-202. 1995
41CTSK
Molecular cloning of human cDNA for cathepsin K: novel cysteine proteinase predominantly expressed in bone.
Inaoka T, Bilbe G, Ishibashi O, Tezuka K, Kumegawa M, Kokubo T.
Biochem Biophys Res Commun 206(1):89-96. 1995