| 1 | CTRB1, CTRB2 |
| A 584 bp deletion in CTRB2 inhibits chymotrypsin B2 activity and secretion and confers risk of pancreatic cancer. | |
| Jermusyk A, Zhong J, Connelly KE, Gordon N, Perera S, Abdolalizadeh E, Zhang T, O'Brien A, Hoskins JW, Collins I, Eiser D, Yuan C; PanScan Consortium; PanC4 Consortium, Risch HA, Jacobs EJ, Li D, Du M, Stolzenberg-Solomon RZ, Klein AP, Smith JP, Wolpin BM, Chanock SJ, Shi J, Petersen GM, Westlake CJ, Amundadottir LT. | |
| Am J Hum Genet. Oct 7;108(10):1852-1865. doi: 10.1016/j.ajhg.2021.09.002. Epub 2021 Sep 23. 2021 | |
| 2 | CTRB1, CTRB2 |
| Chronic pancreatitis: an update on genetic risk factors. | |
| Weiss FU, Skube ME, Lerch MM. | |
| Curr Opin Gastroenterol. Sep;34(5):322-329. doi: 10.1097/MOG.0000000000000461. 2018 | |
| 3 | CFH, CTRB1, PELI3 |
| Protective coding variants in CFH and PELI3 and a variant near CTRB1 are associated with age-related macular degeneration† | |
| Yu Y, Wagner EK, Souied EH, Seitsonen S, Immonen IJ, Häppölä P, Raychaudhuri S, Daly MJ, Seddon JM. | |
| Hum Mol Genet. Dec 1;25(23):5276-5285. doi: 10.1093/hmg/ddw336. 2016 | |
| 4 | CTRB1, CTRB2 |
| Genome-wide association study identifies multiple susceptibility loci for pancreatic cancer. | |
| Wolpin BM, Rizzato C, Kraft P, Kooperberg C, Petersen GM, Wang Z, Arslan AA, Beane-Freeman L, Bracci PM, Buring J, Canzian F, Duell EJ, Gallinger S, Giles GG, Goodman GE, Goodman PJ, Jacobs EJ, Kamineni A, Klein AP, Kolonel LN, Kulke MH, Li D, Malats N, Olson SH, Risch HA, Sesso HD, Visvanathan K, White E, Zheng W, Abnet CC, Albanes D, Andreotti G, Austin MA, Barfield R, Basso D, Berndt SI, Boutron-Ruault MC, Brotzman M, Büchler MW, Bueno-de-Mesquita HB, Bugert P, Burdette L, Campa D, Caporaso NE, Capurso G, Chung C, Cotterchio M, Costello E, Elena J, Funel N, Gaziano JM, Giese NA, Giovannucci EL, Goggins M, Gorman MJ, Gross M, Haiman CA, Hassan M, Helzlsouer KJ, Henderson BE, Holly EA, Hu N, Hunter DJ, Innocenti F, Jenab M, Kaaks R, Key TJ, Khaw KT, Klein EA, Kogevinas M, Krogh V, Kupcinskas J, Kurtz RC, LaCroix A, Landi MT, Landi S, Le Marchand L, Mambrini A, Mannisto S, Milne RL, Nakamura Y, Oberg AL, Owzar K, Patel AV, Peeters PH, Peters U, Pezzilli R, Piepoli A, Porta M, Real FX, Riboli E, Rothman N, Scarpa A, Shu XO, Silverman DT, Soucek P, Sund M, Talar-Wojnarowska R, Taylor PR, Theodoropoulos GE, Thornquist M, Tjønneland A, Tobias GS, Trichopoulos D, Vodicka P, Wactawski-Wende J, Wentzensen N, Wu C, Yu H, Yu K, Zeleniuch-Jacquotte A, Hoover R, Hartge P, Fuchs C, Chanock SJ, Stolzenberg-Solomon RS, Amundadottir LT. | |
| Nat Genet. Sep;46(9):994-1000. doi: 10.1038/ng.3052. Epub 2014 Aug 3. 2014 | |
| 5 | CTRB1, CTRB2 |
| The CTRB1/2 locus affects diabetes susceptibility and treatment via the incretin pathway. | |
| t Hart LM, Fritsche A, Nijpels G, van Leeuwen N, Donnelly LA, Dekker JM, Alssema M, Fadista J, Carlotti F, Gjesing AP, Palmer CN, van Haeften TW, Herzberg-Schäfer SA, Simonis-Bik AM, Houwing-Duistermaat JJ, Helmer Q, Deelen J, Guigas B, Hansen T, Machicao F, Willemsen G, Heine RJ, Kramer MH, Holst JJ, de Koning EJ, Häring HU, Pedersen O, Groop L, de Geus EJ, Slagboom PE, Boomsma DI, Eekhoff EM, Pearson ER, Diamant M. | |
| Diabetes. Sep;62(9):3275-81. doi: 10.2337/db13-0227. Epub 2013 May 14 2013 | |
| 6 | CTRB1, CTRB2 |
| Genomic cloning and partial characterization of human chymotrypsinogen gene. | |
| Hou DX, et al. | |
| Jpn J Hum Genet 38 : 371-380. 1993 | |
| 7 | CTRB1, CDH1 |
| Regional assignment of the human loci for uvomorulin (UVO) and chymotrypsinogen (CTRB) with the help of two overlapping deletions on the long arm of chromosome 16. | |
| Natt E, et al. | |
| Cytogenet Cell Genet 50 : 145-148. 1989 | |
| 8 | TAT, HP, CTRB1 |
| Tyrosine aminotransferase and chymotrypsinogen B are linked to haptoglobin on human chromosome 16q : comparison of genetic and physical distances. | |
| Westphal EM, Burmeister M, Wienker TF, Lehrach H, Bender K, Scherer G. | |
| Genomics 1 : 313-319. 1987 | |
| 9 | TAT, CTRB1 |
| Tyrosine aminotransferase (TAT) and chymotrypsinogen B (CTRB) are linked to HP on human chromosome 16q: comparison of genetical and physical distances. | |
| Westphal EM, et al. | |
| (HGM9) Cytogenet Cell Genet 46 : 714. 1987 | |
| 10 | CTRB1 |
| Chromosomal assignments of human genes for serine proteases trypsin, chymotrypsin B, and elastase. | |
| Honey NK, et al. | |
| Somat Cell Mol Genet 10 : 369-376. 1984 | |
| 11 | PUT1, CTRB1 |
| Studies on the linkage relationship between a new polymorphic membrane polypeptide and HLA loci. | |
| Hamaguchi H, et al. | |
| (HGM7) Cytogenet Cell Genet 37 : 485-486. 1984 | |
| 12 | CTRB1 |
| The chymotrypsinogen B gene (CTRB) is on human chromosome 16. | |
| Sakaguchi AY, et al. | |
| Cytogenet Cell Genet 32 : 313. 1982 | |