| 1 | CTNNB1, RUVBL1
|
| RUVBL1-modulated chromatin remodeling alters the transcriptional activity of oncogenic CTNNB1 in uveal melanoma.
|
| Zhang C, Wu S.
|
| Cell Death Discov. Apr 19;9(1):132. doi: 10.1038/s41420-023-01429-7. 2023
|
| 2 | CTNNB1, TBX4
|
| Heterozygous CTNNB1 and TBX4 variants in a patient with abnormal lung growth, pulmonary hypertension, microcephaly, and spasticity.
|
| Karolak JA, Szafranski P, Kilner D, Patel C, Scurry B, Kinning E, Chandler K, Jhangiani SN, Coban Akdemir ZH, Lupski JR, Popek E, Stankiewicz P.
|
| Clin Genet 96(4):366-370. doi: 10.1111/cge.13605. Epub 2019 Jul 22.
2019
|
| 3 | CTNNB1, TCF4, ZNF433
|
| ZNF433 positively regulates the beta-catenin/ TCF pathway in prostate cancer and enhances the tumorigenicity of cancer cells
|
| Gu S, Hou P, Liu K, Niu X, Wei B, Mao F, Xu Z.
|
| Onco Targets Ther. Feb 1;12:1031-1039. doi: 10.2147/OTT.S178150. 2019
|
| 4 | CTNNB1, MACF1
|
| Mechanical unloading reduces microtubule actin crosslinking factor 1 expression to inhibit β-catenin signaling and osteoblast proliferation.
|
| Yin C, Zhang Y, Hu L, Tian Y, Chen Z, Li D, Zhao F, Su P, Ma X, Zhang G, Miao Z, Wang L, Qian A, Xian CJ.
|
| J Cell Physiol 233(7):5405-5419. doi: 10.1002/jcp.26374. Epub 2018 Jan 23.
2018
|
| 5 | CTNNB1, LEF1, SMAD3, WNT1
|
| The transcription factor Lef1 switches partners from β-catenin to Smad3 during muscle stem cell quiescence.
|
| Aloysius A, DasGupta R, Dhawan J.
|
| Sci Signal 11(540). pii: eaan3000. doi: 10.1126/scisignal.aan3000.
2018
|
| 6 | CTNNB1, ODF2
|
| ODF2 maintains centrosome cohesion by restricting β-catenin accumulation.
|
| Yang K, Tylkowski MA, Hüber D, Contreras CT, Hoyer-Fender S.
|
| J Cell Sci. Oct 24;131(20):jcs220954. doi: 10.1242/jcs.220954 2018
|
| 7 | CTNNB1, FHL2
|
| FHL2 promotes tubular epithelial-to-mesenchymal transition through modulating β-catenin signalling.
|
| Cai T, Sun D, Duan Y, Qiu Y, Dai C, Yang J, He W.
|
| J Cell Mol Med. Mar;22(3):1684-1695. doi: 10.1111/jcmm.13446. Epub 2017 Nov 29. 2018
|
| 8 | CTNNB1, EVR7
|
| Defects in the Cell Signaling Mediator β-Catenin Cause the Retinal Vascular Condition FEVR.
|
| Panagiotou ES, Sanjurjo Soriano C, Poulter JA, Lord EC, Dzulova D, Kondo H, Hiyoshi A, Chung BH, Chu YW, Lai CHY, Tafoya ME, Karjosukarso D, Collin RWJ, Topping J, Downey LM, Ali M, Inglehearn CF, Toomes C.
|
| Am J Hum Genet 100(6):960-968. doi: 10.1016/j.ajhg.2017.05.001.
2017
|
| 9 | CTNNB1, SRCIN1
|
| A Critical Role of Presynaptic Cadherin/Catenin/p140Cap Complexes in Stabilizing Spines and Functional Synapses in the Neocortex.
|
| Li MY, Miao WY, Wu QZ, He SJ, Yan G, Yang Y, Liu JJ, Taketo MM, Yu X.
|
| Neuron 94(6):1155-1172.e8. doi: 10.1016/j.neuron.2017.05.022.
2017
|
| 10 | CTNNB1, TCF7L2
|
| A Critical Role for β-Catenin in Modulating Levels of Insulin Secretion from β-Cells by Regulating Actin Cytoskeleton and Insulin Vesicle Localization.
|
| Sorrenson B, Cognard E, Lee KL, Dissanayake WC, Fu Y, Han W, Hughes WE, Shepherd PR.
|
| J Biol Chem 291(50):25888-25900.
2016
|
| 11 | CDH5, CTNNB1
|
| The RNA-binding protein quaking maintains endothelial barrier function and affects VE-cadherin and β-catenin protein expression.
|
| de Bruin RG, van der Veer EP, Prins J, Lee DH, Dane MJ, Zhang H, Roeten MK, Bijkerk R, de Boer HC, Rabelink TJ, van Zonneveld AJ, van Gils JM.
|
| Sci Rep 6:21643. doi: 10.1038/srep21643.
2016
|
| 12 | CTNNB1, HDAC7, RUNX2
|
| Histone deacetylase 7 (Hdac7) suppresses chondrocyte proliferation and β-catenin activity during endochondral ossification.
|
| Bradley EW, Carpio LR, Olson EN, Westendorf JJ.
|
| J Biol Chem 290(1):118-26. doi: 10.1074/jbc.M114.596247. Epub 2014 Nov 11. 2015
|
| 13 | CTNNB1, YAP1
|
| Cell adhesion. Mechanical strain induces E-cadherin-dependent Yap1 and β-catenin activation to drive cell cycle entry.
|
| Benham-Pyle BW, Pruitt BL, Nelson WJ.
|
| Science 348(6238):1024-7. doi: 10.1126/science.aaa4559.
2015
|
| 14 | CTNNB1
|
| Distinct adhesion-independent functions of β-catenin control stage-specific sensory neurogenesis and proliferation.
|
| Gay MH, Valenta T, Herr P, Paratore-Hari L, Basler K, Sommer L.
|
| BMC Biol 13:24. doi: 10.1186/s12915-015-0134-4.
2015
|
| 15 | CTNNB1
|
| Differential requirements for β-catenin in murine prostate cancer originating from basal versus luminal cells.
|
| Lu TL, Chen CM.
|
| J Pathol 236(3):290-301. doi: 10.1002/path.4521. Epub 2015 Apr 8.
2015
|
| 16 | CTNNB1, GSK3B
|
| Glucose deprivation triggers protein kinase C-dependent β-catenin proteasomal degradation.
|
| Choi SW, Song JK, Yim YS, Yun HG, Chun KH.
|
| J Biol Chem 290(15):9863-73. doi: 10.1074/jbc.M114.606756. Epub 2015 Feb 17.
2015
|
| 17 | CTNNB1, HSPH1
|
| HSP105 recruits protein phosphatase 2A to dephosphorylate β-catenin.
|
| Yu N, Kakunda M, Pham V, Lill JR, Du P, Wongchenko M, Yan Y, Firestein R, Huang X.
|
| Mol Cell Biol 35(8):1390-400. doi: 10.1128/MCB.01307-14. Epub 2015 Feb 2.
2015
|
| 18 | CTNNB1, MRD19
|
| De novo mutations in beta-catenin (CTNNB1) appear to be a frequent cause of intellectual disability: expanding the mutational and clinical spectrum.
|
| Kuechler A, Willemsen MH, Albrecht B, Bacino CA, Bartholomew DW, van Bokhoven H, van den Boogaard MJ, Bramswig N, Büttner C, Cremer K, Czeschik JC, Engels H, van Gassen K, Graf E, van Haelst M, He W, Hogue JS, Kempers M, Koolen D, Monroe G, de Munnik S, Pastore M, Reis A, Reuter MS, Tegay DH, Veltman J, Visser G, van Hasselt P, Smeets EE, Vissers L, Wieland T, Wissink W, Yntema H, Zink AM, Strom TM, Lüdecke HJ, Kleefstra T, Wieczorek D.
|
| Hum Genet 134(1):97-109. doi: 10.1007/s00439-014-1498-1. Epub 2014 Oct 19. 2015
|
| 19 | CDH1, CTNNB1, PROM1
|
| CD133 expression correlates with membrane beta-catenin and E-cadherin loss from human hair follicle placodes during morphogenesis.
|
| Gay DL, Yang CC, Plikus MV, Ito M, Rivera C, Treffeisen E, Doherty L, Spata M, Millar SE, Cotsarelis G.
|
| J Invest Dermatol 135(1):45-55. doi: 10.1038/jid.2014.292. Epub 2014 Jul 10.
2015
|
| 20 | AURKA, CTNNB1, VHL
|
| β-catenin links von Hippel-Lindau to aurora kinase A and loss of primary cilia in renal cell carcinoma.
|
| Dere R, Perkins AL, Bawa-Khalfe T, Jonasch D, Walker CL.
|
| J Am Soc Nephrol 26(3):553-64. doi: 10.1681/ASN.2013090984. Epub 2014 Oct 13.
2015
|
| 21 | BEX2, CTNNB1
|
| Β-catenin is involved in Bex2 down-regulation induced glioma cell invasion/migration inhibition.
|
| Nie E, Zhang X, Xie S, Shi Q, Hu J, Meng Q, Zhou X, Yu R.
|
| Biochem Biophys Res Commun 456(1):494-9. doi: 10.1016/j.bbrc.2014.11.113. Epub 2014 Dec 6.
2015
|
| 22 | CTNNB1, ELAVL1, HSF1
|
| HSF1 regulation of β-catenin in mammary cancer cells through control of HuR/elavL1 expression.
|
| Chou SD, Murshid A, Eguchi T, Gong J, Calderwood SK.
|
| Oncogene ncogene. 2014 Jun 23. doi: 10.1038/onc.2014.177. [Epub ahead of print]
2014
|
| 23 | CTNNB1, TRAF4
|
| TRAF4 participates in Wnt/β-catenin signaling in breast cancer by upregulating β-catenin and mediating its translocation to the nucleus.
|
| Wang A, Wang J, Ren H, Yang F, Sun L, Diao K, Zhao Z, Song M, Cui Z, Wang E, Wei M, Mi X.
|
| Mol Cell Biochem 395(1-2):211-9. doi: 10.1007/s11010-014-2127-y. Epub 2014 Jul 3.
2014
|
| 24 | CTNNB1, MMP7
|
| Matrilysin (MMP-7) catalytic activity regulates β-catenin localization and signaling activation in lung epithelial cells.
|
| Rims CR, McGuire JK.
|
| Exp Lung Res 40(3):126-36. doi: 10.3109/01902148.2014.890681. 2014
|
| 25 | CTNNB1
|
| Targeting β-catenin signaling for therapeutic intervention in MEN1-deficient pancreatic neuroendocrine tumours.
|
| Jiang X, Cao Y, Li F, Su Y, Li Y, Peng Y, Cheng Y, Zhang C, Wang W, Ning G.
|
| Nat Commun 5:5809. doi: 10.1038/ncomms6809.
2014
|
| 26 | CTNNB1, DICER1
|
| β-catenin mediates stress resilience through Dicer1/microRNA regulation.
|
| Dias C, Feng J, Sun H, Shao NY, Mazei-Robison MS, Damez-Werno D, Scobie K, Bagot R, LaBonté B, Ribeiro E, Liu X, Kennedy P, Vialou V, Ferguson D, Peńa C, Calipari ES, Koo JW, Mouzon E, Ghose S, Tamminga C, Neve R, Shen L, Nestler EJ.
|
| Nature 516(7529):51-5. doi: 10.1038/nature13976. Epub 2014 Nov 12.
2014
|
| 27 | CTNNB1
|
| β-catenin contributes to lung tumor development induced by EGFR mutations.
|
| Nakayama S, Sng N, Carretero J, Welner R, Hayashi Y, Yamamoto M, Tan AJ, Yamaguchi N, Yasuda H, Li D, Soejima K, Soo RA, Costa DB, Wong KK, Kobayashi SS.
|
| Cancer Res 74(20):5891-902. doi: 10.1158/0008-5472.CAN-14-0184. Epub 2014 Aug 27.
2014
|
| 28 | CTNNB1, SIRT2
|
| SIRT2 interacts with β-catenin to inhibit Wnt signaling output in response to radiation-induced stress.
|
| Nguyen P, Lee S, Lorang-Leins D, Trepel J, Smart DK.
|
| Mol Cancer Res 12(9):1244-53. doi: 10.1158/1541-7786.MCR-14-0223-T. Epub 2014 May 27.
2014
|
| 29 | CTNNB1
|
| β-Catenin is required for hair-cell differentiation in the cochlea.
|
| Shi F, Hu L, Jacques BE, Mulvaney JF, Dabdoub A, Edge AS.
|
| J Neurosci 34(19):6470-9. doi: 10.1523/JNEUROSCI.4305-13.2014.
2014
|
| 30 | CTNNB1, SKP2
|
| E3-ligase Skp2 regulates β-catenin expression and maintains hematopoietic stem cell homing.
|
| Wang J, Han F, Lee SW, Wu J, Chan CH, Zhang X, Gao Y, Su HK, Feng ZZ, Xu DZ, Lin HK.
|
| Biochem Biophys Res Commun 445(3):566-71. doi: 10.1016/j.bbrc.2014.02.042. Epub 2014 Feb 18.
2014
|
| 31 | CTNNB1, SGK1
|
| Serum and glucocorticoid-regulated kinase 1 promotes vascular smooth muscle cell proliferation via regulation of β-catenin dynamics.
|
| Zhong W, Oguljahan B, Xiao Y, Nelson J, Hernandez L, Garcia-Barrio M, Francis SC.
|
| Cell Signal 26(12):2765-72. doi: 10.1016/j.cellsig.2014.08.002. Epub 2014 Aug 22.
2014
|
| 32 | COPS5, CTNNB1, SIAH1
|
| The β-catenin E3 ubiquitin ligase SIAH-1 is regulated by CSN5/JAB1 in CRC cells.
|
| Jumpertz S, Hennes T, Asare Y, Vervoorts J, Bernhagen J, Schütz AK.
|
| Cell Signal 26(9):2051-9. doi: 10.1016/j.cellsig.2014.05.013. Epub 2014 May 29.
2014
|
| 33 | CTNNB1, SMAD2
|
| Unfolded protein response is required for the definitive endodermal specification of mouse embryonic stem cells via Smad2 and β-catenin signaling.
|
| Xu H, Tsang KS, Wang Y, Chan JC, Xu G, Gao WQ.
|
| J Biol Chem 289(38):26290-301. doi: 10.1074/jbc.M114.572560. Epub 2014 Aug 4.
2014
|
| 34 | CREBBP, CTNNB1, TDG
|
| Thymine DNA glycosylase promotes transactivation of β-catenin/TCFs by cooperating with CBP.
|
| Jia Y, Nie F, Du A, Chen Z, Qin Y, Huang T, Song X, Li L.
|
| J Mol Cell Biol 6(3):231-9. doi: 10.1093/jmcb/mju014. Epub 2014 Apr 18.
2014
|
| 35 | CTNNB1, RSPO1
|
| Wnt/Rspondin/β-catenin signals control axonal sorting and lineage progression in Schwann cell development.
|
| Grigoryan T, Stein S, Qi J, Wende H, Garratt AN, Nave KA, Birchmeier C, Birchmeier W.
|
| Proc Natl Acad Sci U S A 110(45):18174-9. doi: 10.1073/pnas.1310490110. Epub 2013 Oct 22.
2013
|
| 36 | ARRB1, CTNNB1, EDN1
|
| β-arrestin-1 is a nuclear transcriptional regulator of endothelin-1-induced β-catenin signaling.
|
| Rosanň L, Cianfrocca R, Tocci P, Spinella F, Di Castro V, Spadaro F, Salvati E, Biroccio AM, Natali PG, Bagnato A.
|
| Oncogene 32(42):5066-77. doi: 10.1038/onc.2012.527. Epub 2012 Dec 3.
2013
|
| 37 | CDH5, CTNNB1, CTNND1
|
| p120-catenin and β-catenin differentially regulate cadherin adhesive function.
|
| Oas RG, Nanes BA, Esimai CC, Vincent PA, García AJ, Kowalczyk AP.
|
| Mol Biol Cell 24(6):704-14. doi: 10.1091/mbc.E12-06-0471. Epub 2013 Jan 16.
2013
|
| 38 | CTNNB1
|
| CTNNB1 in mesenchyme regulates epithelial cell differentiation during Müllerian duct and postnatal uterine development.
|
| Stewart CA, Wang Y, Bonilla-Claudio M, Martin JF, Gonzalez G, Taketo MM, Behringer RR.
|
| Mol Endocrinol 27(9):1442-54. doi: 10.1210/me.2012-1126. Epub 2013 Jul 31.
2013
|
| 39 | CTNNB1
|
| Thymic epithelial β-catenin is required for adult thymic homeostasis and function.
|
| Liang CC, You LR, Yen JJ, Liao NS, Yang-Yen HF, Chen CM.
|
| Immunol Cell Biol 91(8):511-23. doi: 10.1038/icb.2013.34. Epub 2013 Jul 16.
2013
|
| 40 | CTNNB1
|
| β-Catenin is critical for cerebellar foliation and lamination.
|
| Wen J, Yang HB, Zhou B, Lou HF, Duan S.
|
| PLoS One 8(5):e64451. doi: 10.1371/journal.pone.0064451. Print 2013.
2013
|
| 41 | BRMS1L, CTNNB1, FSHB, GNRH1
|
| β-catenin regulates GnRH-induced FSHβ gene expression.
|
| Wang Q, Chikina M, Zaslavsky E, Pincas H, Sealfon SC.
|
| Mol Endocrinol 27(2):224-37. doi: 10.1210/me.2012-1310. Epub 2012 Dec 4.
2013
|
| 42 | CTNNB1, ZMIZ2
|
| Identification of a novel role of ZMIZ2 protein in regulating the activity of the Wnt/β-catenin signaling pathway.
|
| Lee SH, Zhu C, Peng Y, Johnson DT, Lehmann L, Sun Z.
|
| J Biol Chem 288(50):35913-24. doi: 10.1074/jbc.M113.529727. Epub 2013 Oct 30.
2013
|
| 43 | CCND1, CTNNB1, GLI1, SULF2, WNT1
|
| Activation of the transcription factor GLI1 by WNT signaling underlies the role of SULFATASE 2 as a regulator of tissue regeneration
|
| Nakamura I, Fernandez-Barrena MG, Ortiz-Ruiz MC, Almada LL, Hu C, Elsawa SF, Mills LD, Romecin PA, Gulaid KH, Moser CD, Han JJ, Vrabel A, Hanse EA, Akogyeram NA, Albrecht JH, Monga SPS, Sanderson SO, Prieto J, Roberts LR, Fernandez-Zapico ME.
|
| J Biol Chem. Jul 19;288(29):21389-21398. doi: 10.1074/jbc.M112.443440. Epub 2013 Jun 5. 2013
|
| 44 | CTNNB1, WNT4
|
| CTNNB1 signaling in sertoli cells downregulates spermatogonial stem cell activity via WNT4.
|
| Boyer A, Yeh JR, Zhang X, Paquet M, Gaudin A, Nagano MC, Boerboom D.
|
| PLoS One 7(1):e29764. doi: 10.1371/journal.pone.0029764. Epub 2012 Jan 12.
2012
|
| 45 | CTNNB1, KCNA5
|
| Activation of voltage gated K⁺ channel Kv1.5 by β-catenin.
|
| Munoz C, Tóvolli RH, Sopjani M, Alesutan I, Lam RS, Seebohm G, Föller M, Lang F.
|
| Biochem Biophys Res Commun 417(2):692-6. doi: 10.1016/j.bbrc.2011.11.156. Epub 2011 Dec 7.
2012
|
| 46 | CTNNB1
|
| A dual function for canonical Wnt/β-catenin signaling in the developing mammalian cochlea.
|
| Jacques BE, Puligilla C, Weichert RM, Ferrer-Vaquer A, Hadjantonakis AK, Kelley MW, Dabdoub A.
|
| Development 139(23):4395-404. doi: 10.1242/dev.080358.
2012
|
| 47 | CDX4, CTNNB1, FGF2, HOXA10
|
| β-Catenin activates the HOXA10 and CDX4 genes in myeloid progenitor cells.
|
| Bei L, Shah C, Wang H, Huang W, Roy R, Eklund EA.
|
| J Biol Chem 287(47):39589-601. doi: 10.1074/jbc.M112.402172. Epub 2012 Oct 4.
2012
|
| 48 | CTNNB1, SIRT1, ZG16B
|
| SIRT1 inhibits proliferation of pancreatic cancer cells expressing pancreatic adenocarcinoma up-regulated factor (PAUF), a novel oncogene, by suppression of β-catenin.
|
| Cho IR, Koh SS, Malilas W, Srisuttee R, Moon J, Choi YW, Horio Y, Oh S, Chung YH.
|
| Biochem Biophys Res Commun 423(2):270-5. doi: 10.1016/j.bbrc.2012.05.107. Epub 2012 May 26.
2012
|
| 49 | CDH5, CTNNB1, PTPN11
|
| The tyrosine phosphatase SHP2 regulates recovery of endothelial adherens junctions through control of β-catenin phosphorylation.
|
| Timmerman I, Hoogenboezem M, Bennett AM, Geerts D, Hordijk PL, van Buul JD.
|
| Mol Biol Cell 23(21):4212-25. doi: 10.1091/mbc.E12-01-0038. Epub 2012 Sep 5.
2012
|
| 50 | BCL2L1, BIRC5, CTNNB1, TBX5, YAP1, YES1
|
| β-Catenin-driven cancers require a YAP1 transcriptional complex for survival and tumorigenesis.
|
| Rosenbluh J, Nijhawan D, Cox AG, Li X, Neal JT, Schafer EJ, Zack TI, Wang X, Tsherniak A, Schinzel AC, Shao DD, Schumacher SE, Weir BA, Vazquez F, Cowley GS, Root DE, Mesirov JP, Beroukhim R, Kuo CJ, Goessling W, Hahn WC.
|
| Cell 151(7):1457-73. doi: 10.1016/j.cell.2012.11.026. Epub 2012 Dec 13. Erratum in: Cell. 2013 Mar 28;153(1):267-70.
2012
|
| 51 | AMH, CTNNB1
|
| β-Catenin is essential for Müllerian duct regression during male sexual differentiation.
|
| Kobayashi A, Stewart CA, Wang Y, Fujioka K, Thomas NC, Jamin SP, Behringer RR.
|
| Development 138(10):1967-75. Epub 2011 Apr 13.
2011
|
| 52 | CTNNB1, HDAC6, PRKCA
|
| PKC alpha regulates Sendai virus-mediated interferon induction through HDAC6 and β-catenin.
|
| Zhu J, Coyne CB, Sarkar SN.
|
| EMBO J 30(23):4838-49. doi: 10.1038/emboj.2011.351.
2011
|
| 53 | CTNNB1, TCF4, ZEB1
|
| β-catenin/TCF4 complex induces the epithelial-to-mesenchymal transition (EMT)-activator ZEB1 to regulate tumor invasiveness.
|
| Sánchez-Tilló E, de Barrios O, Siles L, Cuatrecasas M, Castells A, Postigo A.
|
| Proc Natl Acad Sci U S A 108(48):19204-9. doi: 10.1073/pnas.1108977108. Epub 2011 Nov 11. 2011
|
| 54 | ARHGEF7, CTNNB1, SCRIB
|
| β-Pix modulates actin-mediated recruitment of synaptic vesicles to synapses.
|
| Sun Y, Bamji SX.
|
| J Neurosci 31(47):17123-33. doi: 10.1523/JNEUROSCI.2359-11.2011.
2011
|
| 55 | AXIN2, CEP250, CTNNB1
|
| Conductin/axin2 and Wnt signalling regulates centrosome cohesion.
|
| Hadjihannas MV, Brückner M, Behrens J.
|
| EMBO Rep 11(4):317-24. Epub 2010 Mar 19.PMID: 20300119 2010
|
| 56 | APC, CTNNB1, DISC1, DLG4, FZD1, GSK3B, NEUROD1, PRICKLE1, SFRP1, SYN1, WNT1, WNT3, WNT3A, WNT5A, WNT7A
|
| Emerging roles of Wnts in the adult nervous system.
|
| Inestrosa NC, Arenas E.
|
| Nat Rev Neurosci. 11(2):77-86. 2010
|
| 57 | CTNNB1, DKK3
|
| Dkk3, downregulated in cervical cancer, functions as a negative regulator of beta-catenin.
|
| Lee EJ, Jo M, Rho SB, Park K, Yoo YN, Park J, Chae M, Zhang W, Lee JH.
|
| Int J Cancer 124(2):287-97.
2009
|
| 58 | CTNNB1, MEN1
|
| Nuclear-cytoplasmic shuttling of menin regulates nuclear translocation of {beta}-catenin.
|
| Cao Y, Liu R, Jiang X, Lu J, Jiang J, Zhang C, Li X, Ning G.
|
| Mol Cell Biol 29(20):5477-87. Epub 2009 Aug 3.
2009
|
| 59 | CTNNB1
|
| Multiple roles of beta-catenin in controlling the neurogenic niche for midbrain dopamine neurons.
|
| Tang M, Miyamoto Y, Huang EJ.
|
| Development. 136(12):2027-38. 2009
|
| 60 | AMER1, CTNNB1, WT1
|
| Wilms tumor genetics: mutations in WT1, WTX, and CTNNB1 account for only about one-third of tumors.
|
| Ruteshouser EC, Robinson SM, Huff V.
|
| Genes Chromosomes Cancer 47(6):461-70. 2008
|
| 61 | LRP6, GSK3A, GSK3B, CTNNB1, AXIN1
|
| LRP6 transduces a canonical Wnt signal independently of Axin degradation by inhibiting GSK3's phosphorylation of beta-catenin.
|
| Cselenyi CS, Jernigan KK, Tahinci E, Thorne CA, Lee LA, Lee E.
|
| Proc Natl Acad Sci U S A 105(23):8032-7. Epub 2008 May 28. 2008
|
| 62 | CTNNB1, SOX9
|
| Stabilization of beta-catenin in XY gonads causes male-to-female sex-reversal.
|
| Maatouk DM, DiNapoli L, Alvers A, Parker KL, Taketo MM, Capel B.
|
| Hum Mol Genet 17(19):2949-55. Epub 2008 Jul 9.
2008
|
| 63 | CTNNB1
|
| Unique phenotype of hepatocellular cancers with exon-3 mutations in beta-catenin gene.
|
| Cieply B, Zeng G, Proverbs-Singh T, Geller DA, Monga SP.
|
| Hepatology epatology. 2008 Oct 24. [Epub ahead of print]
2008
|
| 64 | CTNNB1
|
| Specific mutations in the beta-catenin gene (CTNNB1) correlate with local recurrence in sporadic desmoid tumors.
|
| Lazar AJ, Tuvin D, Hajibashi S, Habeeb S, Bolshakov S, Mayordomo-Aranda E, Warneke CL, Lopez-Terrada D, Pollock RE, Lev D.
|
| Am J Pathol 173(5):1518-27. Epub 2008 Oct 2.
2008
|
| 65 | CTNNB1
|
| Beta-catenin signalling in mesenchymal islet-derived precursor cells.
|
| Ikonomou L, Geras-Raaka E, Raaka BM, Gershengorn MC.
|
| Cell Prolif 41(3):474-91. Epub 2008 Apr 14.
2008
|
| 66 | CTNNB1
|
| Beta-catenin is required for memory consolidation.
|
| Maguschak KA, Ressler KJ.
|
| Nat Neurosci. 11(11):1319-26 2008
|
| 67 | CTNNB1, PSEN1, PTPRF
|
| Presenilin/gamma-secretase-mediated cleavage regulates association of leukocyte-common antigen-related (LAR) receptor tyrosine phosphatase with beta-catenin.
|
| Haapasalo A, Kim DY, Carey BW, Turunen MK, Pettingell WH, Kovacs DM.
|
| J Biol Chem 282(12):9063-72. Epub 2007 Jan 26. 2007
|
| 68 | CTNNB1, GLIS2
|
| The Kruppel-like zinc finger protein Glis2 functions as a negative modulator of the Wnt/beta-catenin signaling pathway.
|
| Kim YS, Kang HS, Jetten AM.
|
| FEBS Lett 581(5):858-64. Epub 2007 Feb 2. 2007
|
| 69 | CTNNB1,ISL1
|
| Beta-catenin directly regulates Islet1 expression in cardiovascular progenitors and is required for multiple aspects of cardiogenesis.
|
| Lin L, Cui L, Zhou W, Dufort D, Zhang X, Cai CL, Bu L, Yang L, Martin J, Kemler R, Rosenfeld MG, Chen J, Evans SM.
|
| Proc Natl Acad Sci U S A 104(22):9313-8. Epub 2007 May 22. 2007
|
| 70 | VHL, CTNNB1
|
| The von Hippel-Lindau tumor suppressor gene product represses oncogenic beta-catenin signaling in renal carcinoma cells.
|
| Peruzzi B, Athauda G, Bottaro DP.
|
| Proc Natl Acad Sci U S A 103(39):14531-6. Epub 2006 Sep 18. 2006
|
| 71 | MED12, CTNNB1
|
| Mediator is a transducer of Wnt/beta-catenin signaling.
|
| Kim S, Xu X, Hecht A, Boyer TG.
|
| J Biol Chem 281(20):14066-75. Epub 2006 Mar 24. 2006
|
| 72 | APC, CTNNB1, WNT1, AXIN2
|
| Wnt pathway mutations selected by optimal beta-catenin signaling for tumorigenesis.
|
| Cho KH, Baek S, Sung MH.
|
| FEBS Lett 580(15):3665-70. Epub 2006 Jun 5. 2006
|
| 73 | WNT1, CTNNB1
|
| The ups and downs of Wnt signaling in prevalent neurological disorders.
|
| De Ferrari GV, Moon RT.
|
| Oncogene 25(57):7545-53. Review. 2006
|
| 74 | CTNNB1
|
| Functional interaction between beta-catenin and FOXO in oxidative stress signaling.
|
| Essers MA, de Vries-Smits LM, Barker N, Polderman PE, Burgering BM, Korswagen HC.
|
| Science 308(5725):1181-4. 2005
|
| 75 | HDGC, CDH1, CTNNB1
|
| Gastric cancer: new genetic developments.
|
| Lynch HT, Grady W, Suriano G, Huntsman D.
|
| J Surg Oncol 90(3):114-33; discussion 133. 2005
|
| 76 | AXIN1, CTNNB1
|
| Mutations of beta-catenin and AXIN I genes are a late event in human hepatocellular carcinogenesis.
|
| Park JY, Park WS, Nam SW, Kim SY, Lee SH, Yoo NJ, Lee JY, Park CK.
|
| Liver Int 25(1):70-6. 2005
|
| 77 | CTNNA1, CTNNA2, CTNNB1, JUP
|
| Expression of Catenin family members CTNNA1, CTNNA2, CTNNB1 and JUP in the primate prefrontal cortex and hippocampus.
|
| Smith A, Bourdeau I, Wang J, Bondy CA.
|
| Brain Res Mol Brain Res 135(1-2):225-31.
2005
|
| 78 | CTNNB1
|
| Identification of a role for beta-catenin in the establishment of a bipolar mitotic spindle.
|
| Kaplan DD, Meigs TE, Kelly P, Casey PJ.
|
| J Biol Chem 279(12):10829-32. Epub 2004 Jan 26. 2004
|
| 79 | SOX9, CTNNB1
|
| Interactions between Sox9 and beta-catenin control chondrocyte differentiation.
|
| Akiyama H, Lyons JP, Mori-Akiyama Y, Yang X, Zhang R, Zhang Z, Deng JM, Taketo MM, Nakamura T, Behringer RR, McCrea PD, de Crombrugghe B.
|
| Genes Dev 18(9):1072-87. 2004
|
| 80 | ETV4, JUN, SPP1, CTNNB1
|
| Ets gene PEA3 cooperates with beta-catenin-Lef-1 and c-Jun in regulation of osteopontin transcription.
|
| El-Tanani M, Platt-Higgins A, Rudland PS, Campbell FC.
|
| J Biol Chem 279(20):20794-806. Epub 2004 Feb 27. 2004
|
| 81 | PIN1, CTNNB1
|
| PIN1 overexpression and beta-catenin gene mutations are distinct oncogenic events in human hepatocellular carcinoma.
|
| Pang R, Yuen J, Yuen MF, Lai CL, Lee TK, Man K, Poon RT, Fan ST, Wong CM, Ng IO, Kwong YL, Tse E.
|
| Oncogene 23(23):4182-6. 2004
|
| 82 | APC, CTNNB1
|
| The Wnt/beta-catenin pathway regulates cardiac valve formation.
|
| Hurlstone AF, Haramis AP, Wienholds E, Begthel H, Korving J, Van Eeden F, Cuppen E, Zivkovic D, Plasterk RH, Clevers H.
|
| Nature 425(6958):633-7. 2003
|
| 83 | CTNNB1
|
| Beta-catenin inhibits cell growth of a malignant mesothelioma cell line, NCI-H28, with a 3p21.3 homozygous deletion.
|
| Usami N, Sekido Y, Maeda O, Yamamoto K, Minna JD, Hasegawa Y, Yoshioka H, Imaizumi M, Ueda Y, Takahashi M, Shimokata K.
|
| Oncogene 22(39):7923-30. 2003
|
| 84 | APC, BTRC, CTNNB1
|
| APC/CTNNB1 (beta-catenin) pathway alterations in human prostate cancers.
|
| Gerstein AV, Almeida TA, Zhao G, Chess E, Shih IeM, Buhler K, Pienta K, Rubin MA, Vessella R, Papadopoulos N.
|
| Genes Chromosomes Cancer 34(1):9-16. 2002
|
| 85 | CTNNB1, MMP14
|
| Identification of membrane-type matrix metalloproteinase-1 as a target of the beta-catenin/Tcf4 complex in human colorectal cancers.
|
| Takahashi M, Tsunoda T, Seiki M, Nakamura Y, Furukawa Y.
|
| Oncogene 21(38):5861-7. 2002
|
| 86 | CTNNB1
|
| beta-Catenin controls hair follicle morphogenesis and stem cell differentiation in the skin.
|
| Huelsken J, Vogel R, Erdmann B, Cotsarelis G, Birchmeier W.
|
| Cell 105(4):533-45. 2001
|
| 87 | CDH1, CTNNB1
|
| The structure of the beta-catenin/E-cadherin complex and the molecular basis of diverse ligand recognition by beta-catenin.
|
| Huber AH, Weis WI.
|
| Cell 105(3):391-402. 2001
|
| 88 | CTNNB1
|
| Constitutive activation of the Wnt signaling pathway by CTNNB1 (beta-catenin) mutations in a subset of human lung adenocarcinoma.
|
| Sunaga N, Kohno T, Kolligs FT, Fearon ER, Saito R, Yokota J.
|
| Genes Chromosomes Cancer 30(3):316-21. 2001
|
| 89 | CTNNB1
|
| beta-catenin expression in pilomatrixomas. Relationship with beta-catenin gene mutations and comparison with beta-catenin expression in normal hair follicles.
|
| Moreno-Bueno G, Gamallo C, Pérez-Gallego L, Contreras F, Palacios J.
|
| Br J Dermatol 145(4):576-81.
2001
|
| 90 | CTNNB1, STK11
|
| Somatic mutations of LKB1 and beta-catenin genes in gastrointestinal polyps from patients with Peutz-Jeghers syndrome.
|
| Miyaki M, Iijima T, Hosono K, Ishii R, Yasuno M, Mori T, Toi M, Hishima T, Shitara N, Tamura K, Utsunomiya J, Kobayashi N, Kuroki T, Iwama T.
|
| Cancer Res 60(22):6311-3. 2000
|
| 91 | CTNNB1
|
| Activation of the beta-catenin gene by interstitial deletions involving exon 3 as an early event in colorectal tumorigenesis.
|
| Murata M, Iwao K, Miyoshi Y, Nagasawa Y, Yabu M, Himeno S, Imanishi K, Ohsawa M, Wada H, Tominaga S, Shimano T, Kobayashi T, Nakamura Y.
|
| Cancer Lett 159(1):73-8. 2000
|
| 92 | APC, CTNNB1, FAP
|
| Target genes of beta-catenin-T cell-factor/lymphoid-enhancer-factor signaling in human colorectal carcinomas.
|
| Mann B, et al.
|
| Proc Natl Acad Sci U S A 96 : 1603-1608. 1999
|
| 93 | CTNNB1
|
| A common human skin tumour is caused by activating mutations in beta-catenin.
|
| Chan EF, et al.
|
| Nat Genet 21(4):410-3. 1999
|
| 94 | CTNNB1
|
| Mutations of the beta-catenin gene in endometrial carcinomas.
|
| Kobayashi K, et al.
|
| Jpn J Cancer Res 90(1):55-9. 1999
|
| 95 | CTNNB1
|
| Beta-catenin accumulation and mutation of the CTNNB1 gene in hepatoblastoma.
|
| Blaker H, et al.
|
| Genes Chromosomes Cancer 25(4):399-402. 1999
|
| 96 | APC, CTNNB1, FAP
|
| Germline mutations are frequent in the APC gene but absent in the beta-catenin gene in familial adenomatous polyposis patients.
|
| Cao X, et al.
|
| Genes Chromosomes Cancer 25(4):396-8. 1999
|
| 97 | CTNNB1
|
| Frequent mutation and nuclear localization of beta-catenin in anaplastic thyroid carcinoma.
|
| Garcia-Rostan G, et al.
|
| Cancer Res 59(8):1811-5. 1999
|
| 98 | CTNNB1
|
| Mutational analysis of beta-catenin gene in Japanese ovarian carcinomas: frequent mutations in endometrioid carcinomas.
|
| Sagae S, et al.
|
| Jpn J Cancer Res 90(5):510-5. 1999
|
| 99 | CTNNB1
|
| Biology of presenilins as causative molecules for Alzheimer disease.
|
| Nishimura M, et al.
|
| Clin Genet 55(4):219-25. Review. 1999
|
| 100 | CTNNB1
|
| Frequent somatic mutations of the beta-catenin gene in intestinal-type gastric cancer.
|
| Park WS, Oh RR, Park JY, Lee SH, Shin MS, Kim YS, Kim SY, Lee HK, Kim PJ, Oh ST, Yoo NJ, Lee JY.
|
| Cancer Res 59(17):4257-60 1999
|
| 101 | CTNNB1
|
| Mutational activation of the beta-catenin proto-oncogene is a common event in the development of Wilms' tumors.
|
| Koesters R, Ridder R, Kopp-Schneider A, Betts D, Adams V, Niggli F, Briner J, von Knebel Doeberitz M.
|
| Cancer Res 59(16):3880-2 1999
|
| 102 | APC, CTNNB1, FAP
|
| Frequent mutation of beta-catenin and APC genes in primary colorectal tumors from patients with hereditary nonpolyposis colorectal cancer.
|
| Miyaki M, Iijima T, Kimura J, Yasuno M, Mori T, Hayashi Y, Koike M, Shitara N, Iwama T, Kuroki T.
|
| Cancer Res 59(18):4506-9 1999
|
| 103 | CTNNB1
|
| Predominance of beta-catenin mutations and beta-catenin dysregulation in sporadic aggressive fibromatosis (desmoid tumor).
|
| Tejpar S, Nollet F, Li C, Wunder JS, Michils G, dal Cin P, Van Cutsem E, Bapat B, van Roy F, Cassiman JJ, Alman BA.
|
| Oncogene 18(47):6615-20 1999
|
| 104 | CTNNB1
|
| Mutations in the beta-catenin gene (CTNNB1) in endometrioid ovarian carcinomas.
|
| Palacios J, et al.
|
| Cancer Res 58 : 1344-1347. 1998
|
| 105 | CTNNB1
|
| A beta-catenin mutation in a sporadic colorectal tumor of the RER phenotype and absence fo beta-catenin germline mutations in FAP patients.
|
| Mller O, et al.
|
| Genes Chromosomes Cancer 22 : 37-41. 1998
|
| 106 | CTNNB1, DLEC1
|
| Beta-catenin mutations in human prostate cancer.
|
| Voeller HJ, et al.
|
| Cancer Res 58 : 2520-2523. 1998
|
| 107 | APC, AXIN1, CTNNB1, GSK3B
|
| Axin, an inhibitor of the Wnt signalling pathway, interacts with beta-catenin, GSK-3beta and APC and reduces the beta-catenin level.
|
| Nakamura T, Hamada F, Ishidate T, Anai K, Kawahara K, Toyoshima K, Akiyama T.
|
| Genes Cells 3 : 395-403. 1998
|
| 108 | AXIN1, CTNNB1, GSK3B
|
| Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3beta and beta-catenin and promotes GSK-3beta-dependent phosphorylation of beta-catenin.
|
| Ikeda S, et al.
|
| EMBO J 17 : 1371-1384. 1998
|
| 109 | CTNNB1, DLEC1
|
| Beta-catenin mutation in carcinoma of the uterine endometrium.
|
| Fukuchi T, Sakamoto M, Tsuda H, Maruyama K, Nozawa S, Hirohashi S.
|
| Cancer Res 58 : 3526-3528. 1998
|
| 110 | CTNNB1
|
| De novo hair follicle morphogenesis and hair tumors in mice expressing a truncated beta-catenin in skin.
|
| Gat U, et al.
|
| Cell 95 : 605-614. 1998
|
| 111 | CTNNB1
|
| Frequent mutations in the beta-catenin gene in desmoid tumors from patients without familial adenomatous polyposis.
|
| Miyoshi Y, et al.
|
| Oncol Res 10(11-12):591-4. 1998
|
| 112 | CTNNB1, RUVBL2
|
| Pontin52, an interaction partner of beta-catenin, binds to the TATA box binding protein.
|
| Bauer A, Huber O, Kemler R.
|
| Proc Natl Acad Sci U S A 95(25):14787-92. 1998
|
| 113 | APC, CTNNB1, LEF1, FAP
|
| Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC.
|
| Morin PJ, et al.
|
| Science 275 : 1787-1790. 1997
|
| 114 | CTNNB1
|
| Stabilization of beta-catenin by genetic defects in melanoma cell lines.
|
| Rubinfeld B, et al.
|
| Science 275 : 1790-1792. 1997
|
| 115 | APC, CTNNB1, TCF7L2, FAP
|
| Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma.
|
| Korinek V, et al.
|
| Science 275 : 1784-1787. 1997
|
| 116 | CTNNB1
|
| Characterization of the human beta-catenin gene.
|
| Norris AL, et al.
|
| Mamm Genome 7 : 160-162. 1996
|
| 117 | CTNNB1
|
| Genomic organization of the human beta-catenin gene (CTNNB1).
|
| Nollet F, et al.
|
| Genomics 32 : 413-424. 1996
|
| 118 | CTNNB1
|
| The gene for the APC-binding protein beta-catenin (CTNNB1) maps to chromosome 3p22, a region frequently altered in human malignancies.
|
| Trent JM, et al.
|
| Cytogenet Cell Genet 71 : 343-344. 1995
|
| 119 | CTNNB1
|
| Assignment of the human beta-catenin gene (CTNNB1) to 3p22-p21.3 by fluorescence in situ hybridization.
|
| Van Hengel J, et al.
|
| Cytogenet Cell Genet 70 : 68-70. 1995
|
| 120 | CTNNB1
|
| Yeast artificial chromosome cloning of the beta-catenin locus on human chromosome 3p21-22.
|
| Bailey A, et al.
|
| Chromosome Res 3 : 201-203. 1995
|
| 121 | CTNNB1, ERBB2
|
| c-erbB-2 gene product directly associates with beta-catenin and plakoglobin.
|
| Kanai Y, Ochiai A, Shibata T, Oyama T, Ushijima S, Akimoto S, Hirohashi S.
|
| Biochem Biophys Res Commun 208(3):1067-72.
1995
|
| 122 | CTNNB1
|
| Localization of the human beta-catenin gene (CTNNB1) to 3p21 : a region implicated in tumor development.
|
| Kraus C, et al.
|
| Genomics 23 : 272-274. 1994
|
| 123 | APC, CTNNB1, CTNND1, JUP, KPNA3, ARVCF, CTNND2, KPNA2, PKP4, PKP1, PKP2, SPAG6
|
| A repeating amino acid motif shared by proteins with diverse cellular roles.
|
| Peifer M, et al.
|
| Cell 76(5):789-91. No abstract available 1994
|