| 1 | CTH
|
| Hydrogen sulfide-producing cystathionine γ-lyase is critical in the progression of kidney fibrosis.
|
| Han SJ, Noh MR, Jung JM, Ishii I, Yoo J, Kim JI, Park KM.
|
| Free Radic Biol Med 112:423-432. doi: 10.1016/j.freeradbiomed.2017.08.017. Epub 2017 Aug 24.
2017
|
| 2 | CTH
|
| Cystathionine γ-lyase is expressed in human atherosclerotic plaque microvessels and is involved in micro-angiogenesis.
|
| van den Born JC, Mencke R, Conroy S, Zeebregts CJ, van Goor H, Hillebrands JL.
|
| Sci Rep 6:34608. doi: 10.1038/srep34608.
2016
|
| 3 | CTH
|
| DNA methylation in cystathionine-γ-lyase (CSE) gene promoter induced by ox-LDL in macrophages and in apoE knockout mice.
|
| Du HP, Li J, You SJ, Wang YL, Wang F, Cao YJ, Hu LF, Liu CF.
|
| Biochem Biophys Res Commun 469(3):776-82. doi: 10.1016/j.bbrc.2015.11.132. Epub 2015 Dec 12.
2016
|
| 4 | CTH, NOX4
|
| Transcriptional Regulation of Cystathionine-γ-Lyase in Endothelial Cells by NADPH Oxidase 4-Dependent Signaling.
|
| Mistry RK, Murray TV, Prysyazhna O, Martin D, Burgoyne JR, Santos C, Eaton P, Shah AM, Brewer AC.
|
| J Biol Chem 291(4):1774-88. doi: 10.1074/jbc.M115.685578. Epub 2015 Nov 30.
2016
|
| 5 | CTH, NOX4
|
| Transcriptional Regulation of Cystathionine-γ-Lyase in Endothelial Cells by NADPH Oxidase 4-Dependent Signaling.
|
| Mistry RK, Murray TV, Prysyazhna O, Martin D, Burgoyne JR, Santos C, Eaton P, Shah AM, Brewer AC.
|
| J Biol Chem 291(4):1774-88. doi: 10.1074/jbc.M115.685578. Epub 2015 Nov 30.
2016
|
| 6 | CBS, CTH
|
| The H2S-generating enzymes cystathionine β-synthase and cystathionine γ-lyase play a role in vascular development during normal lung alveolarization.
|
| Madurga A, Golec A, Pozarska A, Ishii I, Mižíková I, Nardiello C, Vadász I, Herold S, Mayer K, Reichenberger F, Fehrenbach H, Seeger W, Morty RE.
|
| Am J Physiol Lung Cell Mol Physiol 309(7):L710-24. doi: 10.1152/ajplung.00134.2015. Epub 2015 Jul 31.
2015
|
| 7 | CTH
|
| Role of the cystathionine γ lyase/hydrogen sulfide pathway in human melanoma progression.
|
| Panza E, De Cicco P, Armogida C, Scognamiglio G, Gigantino V, Botti G, Germano D, Napolitano M, Papapetropoulos A, Bucci M, Cirino G, Ianaro A.
|
| Pigment Cell Melanoma Res 28(1):61-72. doi: 10.1111/pcmr.12312. Epub 2014 Oct 6.
2015
|
| 8 | CTH
|
| Regulation of cystathionine gamma-lyase/H₂S system and its pathological implication.
|
| Zhao K, Li H, Li S, Yang G.
|
| Front Biosci (Landmark Ed) 19:1355-69. Review.
2014
|
| 9 | CBS, CTH
|
| CBS and CSE are critical for maintenance of mitochondrial function and glucocorticoid production in adrenal cortex.
|
| Wang CN, Liu YJ, Duan GL, Zhao W, Li XH, Zhu XY, Ni X.
|
| Antioxid Redox Signal 21(16):2192-207. doi: 10.1089/ars.2013.5682. Epub 2014 May 27.
2014
|
| 10 | CTH
|
| Regulation of cystathionine γ-lyase in mammalian cells by hypoxia.
|
| Wang M, Guo Z, Wang S.
|
| Biochem Genet 52(1-2):29-37. doi: 10.1007/s10528-013-9624-7. Epub 2013 Jul 13.
2014
|
| 11 | CTH
|
| Cystathionine γ-lyase protects against renal ischemia/reperfusion by modulating oxidative stress.
|
| Bos EM, Wang R, Snijder PM, Boersema M, Damman J, Fu M, Moser J, Hillebrands JL, Ploeg RJ, Yang G, Leuvenink HG, van Goor H.
|
| J Am Soc Nephrol 24(5):759-70. doi: 10.1681/ASN.2012030268. Epub 2013 Feb 28.
2013
|
| 12 | CTH
|
| Characterization of hydrogen sulfide and its synthases, cystathionine β-synthase and cystathionine γ-lyase, in human prostatic tissue and cells.
|
| Guo H, Gai JW, Wang Y, Jin HF, Du JB, Jin J.
|
| Urology 79(2):483.e1-5.
2012
|
| 13 | CTH
|
| Protein phosphorylation involved in the gene expression of the hydrogen sulphide producing enzyme cystathionine γ-lyase in the pancreatic β-cell.
|
| Taniguchi S, Kimura T, Umeki T, Kimura Y, Kimura H, Ishii I, Itoh N, Naito Y, Yamamoto H, Niki I.
|
| Mol Cell Endocrinol 350(1):31-8. Epub 2011 Nov 25.
2012
|
| 14 | CTH
|
| Is cystathionine gamma-lyase protein expressed in the heart?
|
| Fu M, Zhang W, Yang G, Wang R.
|
| Biochem Biophys Res Commun 428(4):469-74. doi: 10.1016/j.bbrc.2012.10.084. Epub 2012 Oct 30.
2012
|
| 15 | CTH, SP1
|
| Specificity protein-1 as a critical regulator of human cystathionine gamma-lyase in smooth muscle cells.
|
| Yang G, Pei Y, Teng H, Cao Q, Wang R.
|
| J Biol Chem 286(30):26450-60. Epub 2011 Jun 9.
2011
|
| 16 | CTH
|
| A critical life-supporting role for cystathionine γ-lyase in the absence of dietary cysteine supply.
|
| Mani S, Yang G, Wang R.
|
| Free Radic Biol Med 50(10):1280-7. Epub 2011 Feb 24.
2011
|
| 17 | CTH, CTHD
|
| Ancient origin of the CTH alelle carrying the c.200C>T (p.T67I) variant in patients with cystathioninuria.
|
| Espinós C, García-Cazorla A, Martínez-Rubio D, Martínez-Martínez E, Vilaseca MA, Pérez-Dueñas B, Kožich V, Palau F, Artuch R.
|
| Clin Genet 78(6):554-9. doi: 10.1111/j.1399-0004.2010.01431.x.
2010
|
| 18 | CTH, CTHD
|
| Cystathionine gamma-lyase deficiency and overproliferation of smooth muscle cells.
|
| Yang G, Wu L, Bryan S, Khaper N, Mani S, Wang R.
|
| Cardiovasc Res 86(3):487-95. Epub 2010 Jan 5.
2010
|
| 19 | CTH, CTHD
|
| Cystathionine gamma-lyase: Clinical, metabolic, genetic, and structural studies.
|
| Kraus JP, Hasek J, Kozich V, Collard R, Venezia S, Janosíková B, Wang J, Stabler SP, Allen RH, Jakobs C, Finn CT, Chien YH, Hwu WL, Hegele RA, Mudd SH.
|
| Mol Genet Metab 97(4):250-9. Epub 2009 Apr 9.
2009
|
| 20 | CTH
|
| Structural basis for the inhibition mechanism of human cystathionine gamma-lyase, an enzyme responsible for the production of H(2)S.
|
| Sun Q, Collins R, Huang S, Holmberg-Schiavone L, Anand GS, Tan CH, van-den-Berg S, Deng LW, Moore PK, Karlberg T, Sivaraman J.
|
| J Biol Chem 284(5):3076-85. Epub 2008 Nov 19.
2009
|
| 21 | CTH
|
| H2S as a physiologic vasorelaxant: hypertension in mice with deletion of cystathionine gamma-lyase.
|
| Yang G, Wu L, Jiang B, Yang W, Qi J, Cao K, Meng Q, Mustafa AK, Mu W, Zhang S, Snyder SH, Wang R.
|
| Science 322(5901):587-90.
2008
|
| 22 | CBS, CTH
|
| Comparative localization of cystathionine beta-synthase and cystathionine gamma-lyase in retina: differences between amphibians and mammals.
|
| Pong WW, Stouracova R, Frank N, Kraus JP, Eldred WD.
|
| J Comp Neurol 505(2):158-65. 2007
|
| 23 | CTH
|
| Pro-apoptotic effect of endogenous H2S on human aorta smooth muscle cells.
|
| Yang G, Wu L, Wang R.
|
| FASEB J 20(3):553-5. Epub 2006 Jan 17.
2006
|
| 24 | CTH
|
| Single nucleotide polymorphism in CTH associated with variation in plasma homocysteine concentration.
|
| Wang J, Huff AM, Spence JD, Hegele RA.
|
| Clin Genet 65(6):483-6. 2004
|
| 25 | CTH
|
| Cystathionine gamma-lyase overexpression inhibits cell proliferation via a H2S-dependent modulation of ERK1/2 phosphorylation and p21Cip/WAK-1.
|
| Yang G, Cao K, Wu L, Wang R.
|
| J Biol Chem 279(47):49199-205. Epub 2004 Sep 3. 2004
|
| 26 | CTH, CTHD
|
| Genomic basis of cystathioninuria (MIM 219500) revealed by multiple mutations in cystathionine gamma-lyase (CTH).
|
| Wang J, Hegele RA.
|
| Hum Genet 112(4):404-8. Epub 2003 Feb 6. 2003
|
| 27 | CTH
|
| Cloning and nucleotide sequence of human liver cDNA encoding for cystathionine gamma-lyase.
|
| Lu Y, O'Dowd BF, Orrego H, Israel Y.
|
| Biochem Biophys Res Commun 189(2):749-58. 1992
|
| 28 | CTH
|
| Cystathionine metabolism in neuroblastoma.
|
| Klein CE, Roberts B, Holcenberg J, Glode LM.
|
| Cancer 62(2):291-8. 1988
|
| 29 | CTH
|
| High performance liquid chromatography determination of cystathionase activity in human and rabbit lenses.
|
| Bergad PL, Rathbun WB.
|
| Ophthalmic Res 18(6):343-8. 1986
|