Citations for
1CSF3R, SCNH
A Truncated G-CSFR Inhibits Apoptosis Induced by Neutrophil Elastase G185R Mutant: Implication for Understanding CSF3R Mutations in Severe Congenital Neutropenia.
Qiu Y, Zhang Y, Hu N, Dong F.
J Biol Chem Biol Chem. 2017 Jan 10. pii: jbc.M116.755157. doi: 10.1074/jbc.M116.755157. [Epub ahead of print] 2017
2CSF3R, SCNH
Granulocyte colony-stimulating factor receptor signaling in severe congenital neutropenia, chronic neutrophilic leukemia, and related malignancies.
Dwivedi P, Greis KD.
Exp Hematol 46:9-20. doi: 10.1016/j.exphem.2016.10.008. Review. 2017
3CSF3, CSF3R, SCNH
GM-CSF stimulates granulopoiesis in a congenital neutropenia patient with loss-of-function biallelic heterozygous CSF3R mutations.
Klimiankou M, Klimenkova O, Uenalan M, Zeidler A, Mellor-Heineke S, Kandabarau S, Skokowa J, Zeidler C, Welte K.
Blood 126(15):1865-7. doi: 10.1182/blood-2015-07-661264. No abstract available. 2015
4ASXL1, CSF3R, SETBP1
ASXL1 mutations are frequent and prognostically detrimental in CSF3R-mutated chronic neutrophilic leukemia.
Elliott MA, Pardanani A, Hanson CA, Lasho TL, Finke CM, Belachew AA, Tefferi A.
Am J Hematol 90(7):653-6. doi: 10.1002/ajh.24031. 2015
5CSF3, CSF3R
G-CSF supports long-term muscle regeneration in mouse models of muscular dystrophy.
Hayashiji N, Yuasa S, Miyagoe-Suzuki Y, Hara M, Ito N, Hashimoto H, Kusumoto D, Seki T, Tohyama S, Kodaira M, Kunitomi A, Kashimura S, Takei M, Saito Y, Okata S, Egashira T, Endo J, Sasaoka T, Takeda S, Fukuda K.
Nat Commun 6:6745. doi: 10.1038/ncomms7745. Erratum in: Nat Commun. 2015;6:7295. 2015
6CSF3R, SCNH
Inherited biallelic CSF3R mutations in severe congenital neutropenia.
Triot A, Järvinen PM, Arostegui JI, Murugan D, Kohistani N, Dapena Díaz JL, Racek T, Puchałka J, Gertz EM, Schäffer AA, Kotlarz D, Pfeifer D, Díaz de Heredia Rubio C, Ozdemir MA, Patiroglu T, Karakukcu M, Sánchez de Toledo Codina J, Yagüe J, Touw IP, Unal E, Klein C.
Blood 123(24):3811-7. doi: 10.1182/blood-2013-11-535419. 2014
7CSF3R, FBXW7, GSK3B
E3 ubiquitin ligase Fbw7 negatively regulates granulocytic differentiation by targeting G-CSFR for degradation.
Lochab S, Pal P, Kapoor I, Kanaujiya JK, Sanyal S, Behre G, Trivedi AK.
Biochim Biophys Acta 1833(12):2639-52. doi: 10.1016/j.bbamcr.2013.06.018. 2013
8CSF3R
Oncogenic CSF3R mutations in chronic neutrophilic leukemia and atypical CML.
Maxson JE, Gotlib J, Pollyea DA, Fleischman AG, Agarwal A, Eide CA, Bottomly D, Wilmot B, McWeeney SK, Tognon CE, Pond JB, Collins RH, Goueli B, Oh ST, Deininger MW, Chang BH, Loriaux MM, Druker BJ, Tyner JW.
N Engl J Med 368(19):1781-90. doi: 10.1056/NEJMoa1214514. 2013
9CSF3R
The granulocyte-colony stimulating factor receptor (G-CSFR) interacts with retinoic acid receptors (RARs) in the regulation of myeloid differentiation.
Chee LC, Hendy J, Purton LE, McArthur GA.
J Leukoc Biol 93(2):235-43. doi: 10.1189/jlb.1211609. 2013
10CSF3R, SCNH
An acquired CSF3R mutation in an adult chronic idiopathic neutropenia patient who developed acute myeloid leukaemia.
Ikewaki J, Kawano R, Sato T, Imamura T, Kohno K, Ogata M, Ohtsuka E, Kadota J.
Br J Haematol 157(2):264-6. doi: 10.1111/j.1365-2141.2011.08968.x. No abstract available. 2012
11CSF3R, USP17L6P
The deubiquitinating enzyme DUB2A enhances CSF3 signalling by attenuating lysosomal routing of the CSF3 receptor.
Meenhuis A, Verwijmeren C, Roovers O, Touw IP.
Biochem J 434(2):343-51. 2011
12CSF3R, PRDX4, PTPN1
Peroxiredoxin-controlled G-CSF signalling at the endoplasmic reticulum-early endosome interface.
Palande K, Roovers O, Gits J, Verwijmeren C, Iuchi Y, Fujii J, Neel BG, Karisch R, Tavernier J, Touw IP.
J Cell Sci 124(Pt 21):3695-705. doi: 10.1242/jcs.089656. 2011
13CSF3, CSF3R
G-CSF and its receptor in myeloid malignancy.
Beekman R, Touw IP.
Blood 115(25):5131-6. doi: 10.1182/blood-2010-01-234120. Review. 2010
14CSF3R, SCNH
An activating mutation in the CSF3R gene induces a hereditary chronic neutrophilia.
Plo I, Zhang Y, Le Couédic JP, Nakatake M, Boulet JM, Itaya M, Smith SO, Debili N, Constantinescu SN, Vainchenker W, Louache F, de Botton S.
J Exp Med 206(8):1701-7. Epub 2009 Jul 20.PMID: 19620628 2009
15CSF3R, SOCS3
Site-specific ubiquitination determines lysosomal sorting and signal attenuation of the granulocyte colony-stimulating factor receptor.
Wölfler A, Irandoust M, Meenhuis A, Gits J, Roovers O, Touw IP.
Traffic 10(8):1168-79. Epub 2009 May 12.PMID: 19453968 2009
16CSF3R
Zebrafish granulocyte colony-stimulating factor receptor signaling promotes myelopoiesis and myeloid cell migration.
Liongue C, Hall CJ, O'Connell BA, Crosier P, Ward AC.
Blood 113(11):2535-46. Epub 2009 Jan 12.PMID: 19139076 2009
17CSF3R, SCNH
Functional interaction between mutations in the granulocyte colony-stimulating factor receptor in severe congenital neutropenia.
Ward AC, Gits J, Majeed F, Aprikyan AA, Lewis RS, O'Sullivan LA, Freedman M, Shigdar S, Touw IP, Dale DC, Dror Y.
Br J Haematol 142(4):653-6.PMID: 18513286 2008
18CSF3R, SCNH
G-CSFR ubiquitination critically regulates myeloid cell survival and proliferation.
Ai J, Druhan LJ, Loveland MJ, Avalos BR.
PLoS One 3(10):e3422. Epub 2008 Oct 16.PMID: 18923646 2008
19CSF3R, SCNH
G-CSF receptor mutations in patients with congenital neutropenia.
Germeshausen M, Skokowa J, Ballmaier M, Zeidler C, Welte K.
Curr Opin Hematol 15(4):332-7. Review.PMID: 18536571 2008
20CSF3R, SCNH
Incidence of CSF3R mutations in severe congenital neutropenia and relevance for leukemogenesis: Results of a long-term survey.
Germeshausen M, Ballmaier M, Welte K.
Blood 109(1):93-9. Epub 2006 Sep 19. 2007
21CSF3R
Unique structural determinants for Stat3 recruitment and activation by the granulocyte colony-stimulating factor receptor at phosphotyrosine ligands 704 and 744.
Shao H, Xu X, Jing N, Tweardy DJ.
J Immunol 176(5):2933-41. 2006
22CSF3R
A functional single-nucleotide polymorphism of the G-CSF receptor gene predisposes individuals to high-risk myelodysplastic syndrome.
Wolfler A, Erkeland SJ, Bodner C, Valkhof M, Renner W, Leitner C, Olipitz W, Pfeilstocker M, Tinchon C, Emberger W, Linkesch W, Touw IP, Sill H.
Blood 105(9):3731-6. Epub 2005 Jan 11. 2005
23CSF3R, PBX1, TCF3
The gene encoding the granulocyte colony-stimulating factor receptor is a target for deregulation in pre-B ALL by the t(1;19)-specific oncoprotein E2A-Pbx1.
de Lau WB, Hurenkamp J, Berendes P, Touw IP, Clevers HC, van Dijk MA.
Oncogene 17 : 503-510. 1998
24CSF3R, SCNH
Clinical relevance of point mutations in the cytoplasmic domain of the granulocyte colony-stimulating factor receptor gene in patients with severe congenital neutropenia.
Tidow N, Pilz C, Teichmann B, Muller-Brechlin A, Germeshausen M, Kasper B, Rauprich P, Sykora KW, Welte K.
Blood 89 : 2369-2375. 1997
25CSF3R
A point mutation in the granulocyte colony-stimulating factor receptor (G-CSF-R) gene in a case of acute myeloid leukemia results in the overexpression of a novel G-CSF-R isoform.
Dong F, van Paassen M, van Buitenen C, Hoefsloot LH, Lowenberg B, Touw IP.
Blood 85 : 902-911. 1995
26CSF3R, SCNH
Mutations in the gene for the granulocyte colony-stimulating-factor receptor in patients with acute myeloid leukemia preceded by severe congenital neutropenia.
Dong F, Brynes RK, Tidow N, Welte K, Lowenberg B, Touw IP.
N Engl J Med 333 : 487-493. 1995
27CSF3, CSF3R, SCNH
Identification of a nonsense mutation in the granulocyte-colony-stimulating factor receptor in severe congenital neutropenia.
Dong F, Hoefsloot LH, Schelen AM, Broeders CA, Meijer Y, Veerman AJ, Touw IP, Lowenberg B.
Proc Natl Acad Sci U S A 91 : 4480-4484. 1994
28CSF3R
Molecular cloning of cDNAs for the human granulocyte colony-stimulating factor receptor from HL-60 and mapping of the gene to chromosome region 1p32-34.
Tweardy DJ, Anderson K, Cannizzaro LA, Steinman RA, Croce CM, Huebner K.
Blood 79 : 1148-1154. 1992
29CSF3R
Assignment of the human granulocyte colony-stimulating factor receptor gene (CSF3R) to chromosome 1 at region p35-p34.3.
Inazawa J, Fukunaga R, Seto Y, Nakagawa H, Misawa S, Abe T, Nagata S.
Genomics 10 : 1075-1078. 1991
30CSF3R
Three different mRNAs encoding human granulocyte colony-stimulating factor receptor.
Fukunaga R, Seto Y, Mizushima S, Nagata S.
Proc Natl Acad Sci U S A 87 : 8702-8706. 1990