| 1 | CSF2
|
| The microbiota protects against respiratory infection via GM-CSF signaling.
|
| Brown RL, Sequeira RP, Clarke TB.
|
| Nat Commun 8(1):1512. doi: 10.1038/s41467-017-01803-x.
2017
|
| 2 | CSF2, DPP4
|
| DPP4 truncated GM-CSF and IL-3 manifest distinct receptor-binding and regulatory functions compared with their full-length forms.
|
| O'Leary HA, Capitano M, Cooper S, Mantel C, Boswell HS, Kapur R, Ramdas B, Chan R, Deng L, Qu CK, Broxmeyer HE.
|
| Leukemia 31(11):2468-2478. doi: 10.1038/leu.2017.98. Epub 2017 Mar 27.
2017
|
| 3 | CSF2
|
| Stimulatory versus suppressive effects of GM-CSF on tumor progression in multiple cancer types.
|
| Hong IS.
|
| Exp Mol Med 48(7):e242. doi: 10.1038/emm.2016.64. Review.
2016
|
| 4 | CSF1, CSF2, IL33
|
| Interleukin-33 stimulates GM-CSF and M-CSF production by human endothelial cells.
|
| Montanari E, Stojkovic S, Kaun C, Lemberger CE, de Martin R, Rauscher S, Gröger M, Maurer G, Neumayer C, Huk I, Huber K, Demyanets S, Wojta J.
|
| Thromb Haemost 116(2):317-27. doi: 10.1160/TH15-12-0917. Epub 2016 May 12.
2016
|
| 5 | CSF2, RNF13
|
| Enhanced metastasis in RNF13 knockout mice is mediated by a reduction in GM-CSF levels.
|
| Cheng H, Wang A, Meng J, Zhang Y, Zhu D.
|
| Protein Cell 6(10):746-56. doi: 10.1007/s13238-015-0188-7. Epub 2015 Jul 22.
2015
|
| 6 | CSF2
|
| The Cytokine GM-CSF Drives the Inflammatory Signature of CCR2+ Monocytes and Licenses Autoimmunity.
|
| Croxford AL, Lanzinger M, Hartmann FJ, Schreiner B, Mair F, Pelczar P, Clausen BE, Jung S, Greter M, Becher B.
|
| Immunity 43(3):502-14. doi: 10.1016/j.immuni.2015.08.010. Epub 2015 Sep 1.
2015
|
| 7 | CSF1, CSF2
|
| Specific Contributions of CSF-1 and GM-CSF to the Dynamics of the Mononuclear Phagocyte System.
|
| Louis C, Cook AD, Lacey D, Fleetwood AJ, Vlahos R, Anderson GP, Hamilton JA.
|
| J Immunol 195(1):134-44. doi: 10.4049/jimmunol.1500369. Epub 2015 May 27.
2015
|
| 8 | CSF2, MAFB
|
| MafB antagonizes phenotypic alteration induced by GM-CSF in microglia.
|
| Koshida R, Oishi H, Hamada M, Takahashi S.
|
| Biochem Biophys Res Commun 463(1-2):109-15. doi: 10.1016/j.bbrc.2015.05.036. Epub 2015 May 19.
2015
|
| 9 | CSF2
|
| Granulocyte/Macrophage Colony-stimulating Factor-dependent Dendritic Cells Restrain Lean Adipose Tissue Expansion.
|
| Pamir N, Liu NC, Irwin A, Becker L, Peng Y, Ronsein GE, Bornfeldt KE, Duffield JS, Heinecke JW.
|
| J Biol Chem 290(23):14656-67. doi: 10.1074/jbc.M115.645820. Epub 2015 Apr 30.
2015
|
| 10 | CSF2, TRAF6
|
| TRAF6 is required for the GM-CSF-induced JNK, p38 and Akt activation.
|
| Wang Y, Zhou C, Huo J, Ni Y, Zhang P, Lu C, Jing B, Xiao F, Chen W, Li W, Zhang P, Zhang L.
|
| Mol Immunol 65(2):224-9. doi: 10.1016/j.molimm.2015.01.012. Epub 2015 Feb 17.
2015
|
| 11 | CSF2, PPARG
|
| Induction of the nuclear receptor PPAR-γ by the cytokine GM-CSF is critical for the differentiation of fetal monocytes into alveolar macrophages.
|
| Schneider C, Nobs SP, Kurrer M, Rehrauer H, Thiele C, Kopf M.
|
| Nat Immunol 15(11):1026-37. doi: 10.1038/ni.3005. Epub 2014 Sep 28.
2014
|
| 12 | CSF2
|
| Periodic fever, aphthous stomatitis, pharyngitis and cervical adenopathy syndrome is associated with activation of GM-CSF and burst-like expression of IL-8 in peripheral blood.
|
| Ling E, Israeli M, Klein T, Amir J, Harel L.
|
| Mod Rheumatol 24(6):997-1000. doi: 10.3109/14397595.2014.895122. Epub 2014 Mar 26.
2014
|
| 13 | CCND1, CCNE1, CSF2
|
| GM-CSF induces cyclin D1 expression and proliferation of endothelial progenitor cells via PI3K and MAPK signaling.
|
| Qiu C, Xie Q, Zhang D, Chen Q, Hu J, Xu L.
|
| Cell Physiol Biochem 33(3):784-95. doi: 10.1159/000358652. Epub 2014 Mar 7.
2014
|
| 14 | CSF2
|
| GM-CSF as a therapeutic target in inflammatory diseases.
|
| van Nieuwenhuijze A, Koenders M, Roeleveld D, Sleeman MA, van den Berg W, Wicks IP.
|
| Mol Immunol 56(4):675-82. doi: 10.1016/j.molimm.2013.05.002. Epub 2013 Aug 8. Review.
2013
|
| 15 | CSF2, IL21
|
| The cytokines IL-21 and GM-CSF have opposing regulatory roles in the apoptosis of conventional dendritic cells.
|
| Wan CK, Oh J, Li P, West EE, Wong EA, Andraski AB, Spolski R, Yu ZX, He J, Kelsall BL, Leonard WJ.
|
| Immunity 38(3):514-27. doi: 10.1016/j.immuni.2013.02.011. Epub 2013 Feb 28.
2013
|
| 16 | CSF2, IL2
|
| NF-κB controls Il2 and Csf2 expression during T cell development and activation process.
|
| Li Y, Ohms SJ, Sun C, Fan J.
|
| Mol Biol Rep 40(2):1685-92. doi: 10.1007/s11033-012-2219-2. Epub 2012 Oct 20.
2013
|
| 17 | CSF2, IL2
|
| Depletion of c-Rel from cytokine gene promoters is required for chromatin reassembly and termination of gene responses to T cell activation.
|
| Poke FS, Upcher WR, Sprod OR, Young A, Brettingham-Moore KH, Holloway AF.
|
| PLoS One 7(7):e41734. doi: 10.1371/journal.pone.0041734. Epub 2012 Jul 30.
2012
|
| 18 | CSF2
|
| GM-CSF controls nonlymphoid tissue dendritic cell homeostasis but is dispensable for the differentiation of inflammatory dendritic cells.
|
| Greter M, Helft J, Chow A, Hashimoto D, Mortha A, Agudo-Cantero J, Bogunovic M, Gautier EL, Miller J, Leboeuf M, Lu G, Aloman C, Brown BD, Pollard JW, Xiong H, Randolph GJ, Chipuk JE, Frenette PS, Merad M.
|
| Immunity 36(6):1031-46. doi: 10.1016/j.immuni.2012.03.027.
2012
|
| 19 | CSF2, IKL2
|
| IL-2 and GM-CSF are regulated by DNA demethylation during activation of T cells, B cells and macrophages.
|
| Li Y, Ohms SJ, Shannon FM, Sun C, Fan JY.
|
| Biochem Biophys Res Commun 419(4):748-53. doi: 10.1016/j.bbrc.2012.02.094. Epub 2012 Feb 24.
2012
|
| 20 | CSF2
|
| Control of macrophage lineage populations by CSF-1 receptor and GM-CSF in homeostasis and inflammation.
|
| Lenzo JC, Turner AL, Cook AD, Vlahos R, Anderson GP, Reynolds EC, Hamilton JA.
|
| Immunol Cell Biol 90(4):429-40. doi: 10.1038/icb.2011.58. Epub 2011 Jul 5.
2012
|
| 21 | CSF2, TNF
|
| GM-CSF and TNFα modulate protein expression of human neutrophils visualized by fluorescence two-dimensional difference gel electrophoresis.
|
| Langereis JD, Franciosi L, Ulfman LH, Koenderman L.
|
| Cytokine 56(2):422-9. Epub 2011 Aug 27.
2011
|
| 22 | CSF2
|
| GMCSF in the absence of other cytokines sustains human dendritic cell precursors with T cell regulatory activity and capacity to differentiate into functional dendritic cells.
|
| Chitta S, Santambrogio L, Stern LJ.
|
| Immunol Lett 116(1):41-54. Epub 2007 Dec 10.PMID: 18166231 2008
|
| 23 | CASC3, CSF2
|
| FLIP and MAPK play crucial roles in the MLN51-mediated hyperproliferation of fibroblast-like synoviocytes in the pathogenesis of rheumatoid arthritis.
|
| Ha JE, Choi YE, Jang J, Yoon CH, Kim HY, Bae YS.
|
| FEBS J 275(14):3546-55.
2008
|
| 24 | CSF2, IL1A, IL12B, IL15, IL17A, IL18, IL23A, IL6
|
| Cytokines in the pathogenesis of rheumatoid arthritis.
|
| McInnes IB, Schett G.
|
| Nat Rev Immunol 7(6):429-42. Review. 2007
|
| 25 | CSF2
|
| Role of protein kinase C in expression of granulocyte-colony stimulating factor and granulocyte macrophage-colony stimulating factor in lung cancer cells.
|
| Uemura Y, Kobayashi M, Nakata H, Kubota T, Saito T, Bandobashi K, Taguchi H.
|
| Int J Mol Med 16(5):873-81. 2005
|
| 26 | CSF2, IL13, IL3, IL4, IL4R, IL9, IRF1, TCF7
|
| A second-generation association study of the 5q31 cytokine gene cluster and the interleukin-4 receptor in asthma.
|
| Kauppi P, Lindblad-Toh K, Sevon P, Toivonen HT, Rioux JD, Villapakkam A, Laitinen LA, Hudson TJ, Kere J, Laitinen T.
|
| Genomics 77(1/2):35-42. 2001
|
| 27 | CSF2, MMP14, MMP2
|
| Granulocyte-macrophage colony-stimulating factor upregulates matrix metalloproteinase-2 (MMP-2) and membrane type-1 MMP (MT1-MMP) in human head and neck cancer cells.
|
| Tomita T, Fujii M, Tokumaru Y, Imanishi Y, Kanke M, Yamashita T, Ishiguro R, Kanzaki J, Kameyama K, Otani Y.
|
| Cancer Lett 156(1):83-91. 2000
|
| 28 | ADRA2A, ADRB1, AGTR1, CAFG, CD36, CETP, CSF1, CSF2, CYP11B2, ECE1, EDN1, EDNRA, EDNRB, EGR1, F2R, FGA, FGB, FHBL1, HGF, ICAM1, IGF1, IL1A, IL6, LPA, MGP, MSR1, MTTP, NOS2, NOS3, PDGFA, PDGFRA, SELP, TGFB1, TNF, VCAM1, VDR
|
| Sequence diversity in 36 candidate genes for cardiovascular disorders.
|
| Cambien F, Poirier O, Nicaud V, Herrmann SM, Mallet C, Ricard S, Behague I, Hallet V, Blanc H, Loukaci V, Thillet J, Evans A, Ruidavets JB, Arveiler D, Luc G, Tiret L.
|
| Am J Hum Genet 65(1):183-91. 1999
|
| 29 | NF1, CSF2
|
| Nf1 deficiency causes Ras-mediated granulocyte/macrophage colony stimulating factor hypersensitivity and chronic myeloid leukaemia.
|
| Largaespada DA, et al.
|
| Nat Genet 12 : 137-143. 1996
|
| 30 | EGR1, IL9, CSF2, TSG5D
|
| Physical mapping of the minimal region of loss in 5q- chromosome. (chromosome 5/deletion/leukemia).
|
| Fairman J, et al.
|
| Proc Natl Acad Sci U S A 92 : 7406-7410. 1995
|
| 31 | IL10, IFNG, CSF2
|
| Selective expression of interleukin 10, interferon gamma, and granulocyte-macrophage colony-stimulating factor in ovarian cancer biopsies.
|
| Pisa P, et al.
|
| Proc Natl Acad Sci U S A 89 : 7708-7712. 1992
|
| 32 | IL5, CSF2
|
| Expression of interleukin-5 and granulocyte-macrophage colony-stimulating factor in human peripheral blood mononuclear cells after activation with phorbol myristate acetate.
|
| Staynov DZ, et al.
|
| Immunology 75 : 196-201. 1992
|
| 33 | CSF2, IL3
|
| Linkage mapping of the human CSF2 and IL3 genes.
|
| Frolova EI, et al.
|
| Proc Natl Acad Sci U S A 88 : 4821-4824. 1991
|
| 34 | CSF2, IL3
|
| Molecular organization of the cytokine gene cluster, involving the human IL-3, IL-4, IL-5, and GM-CSF genes, on human chromosome 5.
|
| van Leeuwen BH, et al.
|
| Blood 73 : 1142-1148. 1989
|
| 35 | CSF2, IL3
|
| The human genes for GM-CSF and IL 3 are closely linked in tandem on chromosome 5.
|
| Yang YC, et al.
|
| Blood 71 : 958-961. 1988
|
| 36 | CSF2, IL3
|
| Close genetic and physical linkage between the murine haemopoietic growth factor genes GM-CSF and multi-CSF (IL3).
|
| Barlow DP, et al.
|
| EMBO J 6 : 617-623. 1987
|
| 37 | CSF2
|
| Genomic cloning, characterization, and multilineage growth-promoting activity of human granulocyte-macrophage colony-stimulating factor.
|
| Kaushansky K, et al.
|
| Proc Natl Acad Sci U S A 83 : 3101-3105. 1986
|
| 38 | CSF2
|
| Molecular cloning and expression of cDNA for human granulocyte colony-stimulating factor.
|
| Nagata S, et al.
|
| Nature 319 : 415-418. 1986
|
| 39 | CSF1R, CSF2
|
| Evidence for the involvement of GM-CSF and FMS in the deletion (5q) in myeloid disorders.
|
| Le Beau MM, et al.
|
| Science 231 : 984-987. 1986
|
| 40 | CSF2
|
| The human gene encoding GM-CSF is at 5q21-q32, the chromosome region deleted in the 5q- anomaly.
|
| Huebner K, Isobe M, Croce CM, Golde DW, Kaufman SE, Gasson JC.
|
| Science 230 : 1282-1285. 1985
|